Gene: CD164

8763
DFNA66|MGC-24|MGC-24v|MUC-24|endolyn
CD164 molecule
protein-coding
6q21
Ensembl:ENSG00000135535 MIM:603356 Vega:OTTHUMG00000015339 UniprotKB:Q04900
NG_051926.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.900e-1 (AD)  4.613e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
UBXN40.92
TMED100.917
MARCH70.912
TMED70.911
PICALM0.911
COPB10.909
CAPZA10.906
RAB100.901
TNPO10.896
LMAN10.896

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.718
OR4F29-0.69
HES5-0.186
SPRR2A-0.143
SPRR2D-0.135
PTGDR2-0.134
HMHB1-0.125
KRTAP10-6-0.121
ARSF-0.115
OR10T2-0.114

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CD164 mRNA"19114083
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of CD164 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of CD164 mRNA"21346803
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
C0293704-toluidine4-toluidine results in decreased expression of CD164 mRNA27638505
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of CD164 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CD164 gene27153756
D000485AllergensAllergens results in increased expression of CD164 protein18180381
D000485AllergensDasatinib inhibits the reaction [Allergens results in increased expression of CD164 protein]18180381
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CD164 mRNA16483693
C006632arsenic trioxidearsenic trioxide results in decreased expression of CD164 mRNA19128835
C547126AZM551248AZM551248 results in increased expression of CD164 mRNA22323515
D004958EstradiolEstradiol results in increased expression of CD164 mRNA18556351
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of CD164 mRNA18556351
C006780bisphenol Abisphenol A affects the expression of CD164 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of CD164 mRNA25181051
D002065BuspironeBuspirone results in decreased expression of CD164 mRNA24136188
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of CD164 mRNA23650126
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD164 gene20938992
D019327Copper SulfateCopper Sulfate results in decreased expression of CD164 mRNA19549813
D000069439DasatinibDasatinib inhibits the reaction [Allergens results in increased expression of CD164 protein]18180381
D000069439DasatinibDasatinib results in decreased expression of CD164 protein18180381
D004237DiuronDiuron results in increased expression of CD164 mRNA21551480
D004391DustDust results in decreased expression of CD164 mRNA17805423
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CD164 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD164 mRNA17942748
D005419FlavonoidsFlavonoids results in increased expression of CD164 mRNA18035473
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD164 gene20938992
D005557FormaldehydeFormaldehyde results in increased expression of CD164 mRNA23649840
C056933fumonisin B1fumonisin B1 results in increased expression of CD164 mRNA16221962
C039281furanfuran results in decreased expression of CD164 mRNA26194646
C039281furanfuran results in increased methylation of CD164 gene22079235
D005839GentamicinsGentamicins results in increased expression of CD164 mRNA22061828
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CD164 mRNA20044591
C492448ICG 001ICG 001 results in decreased expression of CD164 mRNA26191083
C410337K 7174K 7174 results in increased expression of CD164 mRNA24086573
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CD164 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CD164 mRNA26272509
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
C051752nefazodonenefazodone results in decreased expression of CD164 mRNA24136188
C012655nimesulidenimesulide results in decreased expression of CD164 mRNA24136188
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD164 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CD164 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of CD164 mRNA20813756
C006253pirinixic acidpirinixic acid results in increased expression of CD164 mRNA16221962
C045362prochlorazprochloraz results in increased expression of CD164 mRNA21470553
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of CD164 mRNA18556351
C513428pyrachlostrobinpyrachlostrobin results in increased expression of CD164 mRNA27029645
D012402RotenoneRotenone results in increased expression of CD164 mRNA23186747
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CD164 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD164 mRNA17942748
D014212TretinoinTretinoin results in increased expression of CD164 mRNA21934132
D014635Valproic AcidValproic Acid results in increased expression of CD164 mRNA28001369

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI17077324  24094005  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0006955immune response-TAS9763543  
GO:0007155cell adhesion-IDA10491205  
GO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-IDA10491205  
GO:0007162negative regulation of cell adhesion-NAS10878358  
GO:0007165signal transduction-TAS9763543  
GO:0007275multicellular organism development-TAS9680353  
GO:0007517muscle organ development-IEA-  
GO:0008285negative regulation of cell proliferation-NAS10878358  
GO:0030097hemopoiesis-NAS11027692  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0005764lysosome-IBA21873635  
GO:0005764lysosome-IDA11027692  
GO:0005765lysosomal membrane-IEA-  
GO:0005768endosome-IBA21873635  
GO:0005768endosome-IDA11027692  26197441  
GO:0005886plasma membrane-IDA10491205  26197441  
GO:0005887integral component of plasma membrane-NAS11027692  
GO:0010008endosome membrane-IEA-  
GO:0031410cytoplasmic vesicle-IBA21873635  
KEGG ID KEGG Term
hsa04142Lysosome
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29133146Association of genetic polymorphisms with erythrocyte traits: Verification of SNPs reported in a previous GWAS in a Japanese population. (2018 Feb 5)Seiki TGene