Gene: NAPG

8774
GAMMASNAP
NSF attachment protein gamma
protein-coding
18p11.22
Ensembl:ENSG00000134265 MIM:603216 Vega:OTTHUMG00000179119 UniprotKB:Q99747
NC_000018.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.983e-1 (AD)  5.160e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
WDR470.98
ATP6V1A0.979
CLTC0.978
VPS350.977
UBE2K0.977
CAND10.976
PJA20.975
SLC25A460.974
SRPK20.974
ATP6V1C10.972

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.581
OR4F29-0.544
CSAG1-0.464
MTRNR2L10-0.406
MTRNR2L6-0.4
HEY2-0.395
MTRNR2L9-0.387
MYL3-0.386
RNF135-0.383
RHOD-0.377

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of NAPG mRNA19933214
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of NAPG mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of NAPG mRNA"21346803
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to NAPG protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NAPG protein]26598702
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of NAPG mRNA21298039
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to NAPG protein]26598702
D001280AtrazineAtrazine results in increased expression of NAPG mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NAPG mRNA21632981|2623829
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NAPG mRNA21715664|2222880
C006780bisphenol Abisphenol A results in decreased expression of NAPG mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of NAPG gene28505145
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NAPG mRNA28628672
C013418bromfenacoumbromfenacoum results in decreased expression of NAPG protein28903499
D019256Cadmium Chloride[nickel chloride co-treated with Cadmium Chloride] results in decreased expression of NAPG mRNA19187980
D003042CocaineCocaine affects the expression of NAPG mRNA20187946
D019327Copper SulfateCopper Sulfate results in increased expression of NAPG mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of NAPG mRNA20106945
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NAPG mRNA28628672
C000944dicrotophosdicrotophos results in decreased expression of NAPG mRNA28302478
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NAPG mRNA22079256
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NAPG mRNA17942748
C082360fipronilfipronil results in increased expression of NAPG mRNA23962444
D005839GentamicinsGentamicins results in decreased expression of NAPG mRNA22061828
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NAPG mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NAPG mRNA28628672
C410337K 7174K 7174 results in increased expression of NAPG mRNA24086573
C017461lead nitrate[nickel chloride co-treated with lead nitrate] results in decreased expression of NAPG mRNA19187980
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of NAPG mRNA28001369
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of NAPG mRNA"20188158
C063855microcystin RRmicrocystin RR results in decreased expression of NAPG protein19111056
C051752nefazodonenefazodone results in increased expression of NAPG mRNA24136188
D009532NickelNickel results in increased expression of NAPG mRNA25583101
C022838nickel chloride[nickel chloride co-treated with Cadmium Chloride] results in decreased expression of NAPG mRNA19187980
C022838nickel chloride[nickel chloride co-treated with lead nitrate] results in decreased expression of NAPG mRNA19187980
D010269ParaquatParaquat results in decreased expression of NAPG mRNA21371552
D010936Plant ExtractsPlant Extracts results in increased expression of NAPG mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NAPG mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of NAPG mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in decreased expression of NAPG mRNA23608068
D012524SarinSarin results in decreased expression of NAPG protein28973502
C080703SK&F 83959SK&F 83959 results in increased expression of NAPG protein25852303
C009277sodium arsenatesodium arsenate results in increased expression of NAPG mRNA23922661
D012969Sodium FluorideSodium Fluoride results in decreased expression of NAPG protein28918527
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NAPG mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NAPG mRNA17942748
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of NAPG protein"25852303
D014520UrethaneUrethane results in increased expression of NAPG mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased methylation of NAPG gene29154799
D014635Valproic AcidValproic Acid results in increased expression of NAPG mRNA23179753|2627250
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of NAPG gene25560391
C025643vinclozolinvinclozolin affects the expression of NAPG mRNA19015723
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NAPG mRNA"27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005483soluble NSF attachment protein activity-IBA21873635  
GO:0005515protein binding-IPI11278501  
GO:0019905syntaxin binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006886intracellular protein transport-IBA21873635  
GO:0006891intra-Golgi vesicle-mediated transport-TAS8455721  
GO:0050821protein stabilization-NAS11278501  
GO:0061025membrane fusion-TAS8455721  
GO:0065003protein-containing complex assembly-NAS11278501  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IDA11278501  
GO:0005765lysosomal membrane-HDA17897319  
GO:0031201SNARE complex-IBA21873635  
GO:0043209myelin sheath-IEA-  
GO:0070062extracellular exosome-HDA18570454  19056867  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-199977ER to Golgi Anterograde TransportTAS
R-HSA-199991Membrane TraffickingTAS
R-HSA-204005COPII-mediated vesicle transportTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-446203Asparagine N-linked glycosylationTAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6807878COPI-mediated anterograde transportTAS
R-HSA-6811434COPI-dependent Golgi-to-ER retrograde trafficTAS
R-HSA-6811438Intra-Golgi trafficTAS
R-HSA-6811440Retrograde transport at the Trans-Golgi-NetworkTAS
R-HSA-6811442Intra-Golgi and retrograde Golgi-to-ER trafficTAS
R-HSA-8856688Golgi-to-ER retrograde transportTAS
R-HSA-948021Transport to the Golgi and subsequent modificationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
11494440[State of the upper respiratory tract in patients with stage I arterial hypertension]. (2001)Voronin IMTer Arkh