Gene: NR1I2

8856
BXR|ONR1|PAR|PAR1|PAR2|PARq|PRR|PXR|SAR|SXR
nuclear receptor subfamily 1 group I member 2
protein-coding
3q13.33
Ensembl:ENSG00000144852 MIM:603065 Vega:OTTHUMG00000159400 UniprotKB:O75469
NG_011856.1
PubMed
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.156e-1 (AD)  9.980e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg16327381chr3:119498036NR1I2Promoter1.215e-5Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADAT20.556
ARMC20.551
RINT10.55
ZNF6110.55
EDEM10.547
EFCAB60.547
NBPF150.546
PIGL0.541
CMPK20.536
FAM122C0.535

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TMEM253-0.297
ETV4-0.289
SERPINC1-0.246
HIGD1B-0.242
SLC25A48-0.242
REP15-0.24
C7orf61-0.228
PLA2G5-0.225
OLIG1-0.223
WNT7B-0.22

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00163Vitamin ESmall Molecule59-02-9Approved|NutraceuticalTarget
DB00239OxiconazoleSmall Molecule64211-45-6ApprovedTarget
DB00252PhenytoinSmall Molecule57-41-0ApprovedTarget
DB00255DiethylstilbestrolSmall Molecule56-53-1Approved|InvestigationalTarget
DB00257ClotrimazoleSmall Molecule23593-75-1ApprovedTarget
DB00312PentobarbitalSmall Molecule76-74-4Approved|InvestigationalTarget
DB00396ProgesteroneSmall Molecule57-83-0ApprovedTarget
DB00421SpironolactoneSmall Molecule52-01-7ApprovedTarget
DB00431LindaneSmall Molecule58-89-9Approved|WithdrawnTarget
DB00499FlutamideSmall Molecule13311-84-7Approved|InvestigationalTarget
DB00503RitonavirSmall Molecule155213-67-5Approved|InvestigationalTarget
DB00530ErlotinibSmall Molecule183321-74-6Approved|InvestigationalTarget
DB00531CyclophosphamideSmall Molecule50-18-0Approved|InvestigationalTarget
DB00532MephenytoinSmall Molecule50-12-4Investigational|WithdrawnTarget
DB00564CarbamazepineSmall Molecule298-46-4Approved|InvestigationalTarget
DB00675TamoxifenSmall Molecule10540-29-1ApprovedTarget
DB00682WarfarinSmall Molecule81-81-2ApprovedTarget
DB00754EthotoinSmall Molecule86-35-1ApprovedTarget
DB00783EstradiolSmall Molecule50-28-2Approved|InvestigationalTarget
DB00834MifepristoneSmall Molecule84371-65-3Approved|InvestigationalTarget
DB00849MethylphenobarbitalSmall Molecule115-38-8ApprovedTarget
DB00977Ethinyl EstradiolSmall Molecule57-63-6ApprovedTarget
DB01026KetoconazoleSmall Molecule65277-42-1Approved|InvestigationalTarget
DB01039FenofibrateSmall Molecule49562-28-9ApprovedTarget
DB01045RifampicinSmall Molecule13292-46-1ApprovedTarget
DB01068ClonazepamSmall Molecule1622-61-3Approved|IllicitTarget
DB01110MiconazoleSmall Molecule22916-47-8Approved|InvestigationalTarget
DB01115NifedipineSmall Molecule21829-25-4ApprovedTarget
DB01127EconazoleSmall Molecule27220-47-9ApprovedTarget
DB01138SulfinpyrazoneSmall Molecule57-96-5ApprovedTarget
DB01174PhenobarbitalSmall Molecule50-06-6Approved|InvestigationalTarget
DB01181IfosfamideSmall Molecule3778-73-2ApprovedTarget
DB01220RifaximinSmall Molecule80621-81-4Approved|InvestigationalTarget
DB01229PaclitaxelSmall Molecule33069-62-4ApprovedTarget
DB01234DexamethasoneSmall Molecule50-02-2Approved|InvestigationalTarget
DB01248DocetaxelSmall Molecule114977-28-5Approved|InvestigationalTarget
DB01393BezafibrateSmall Molecule41859-67-0Approved|InvestigationalTarget
DB01645GenisteinSmall Molecule446-72-0InvestigationalTarget
DB01708PrasteroneSmall Molecule53-43-0Approved|Investigational|NutraceuticalTarget
DB01892HyperforinSmall Molecule11079-53-1NutraceuticalTarget
DB02709ResveratrolSmall Molecule501-36-0Approved|Experimental|InvestigationalTarget
DB02789PregnenoloneSmall Molecule-Approved|Experimental|InvestigationalTarget
DB04216QuercetinSmall Molecule117-39-5Experimental|InvestigationalTarget
DB04466SR12813Small Molecule126411-39-0ExperimentalTarget
DB04468AfimoxifeneSmall Molecule68392-35-8InvestigationalTarget
DB04824PhenolphthaleinSmall Molecule77-09-8Approved|WithdrawnTarget
DB04930PermethrinSmall Molecule52645-53-1Approved|InvestigationalTarget
DB06777Chenodeoxycholic acidSmall Molecule474-25-9ApprovedTarget
DB07080N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB07931HexestrolSmall Molecule84-16-2WithdrawnTarget
DB08604TriclosanSmall Molecule3380-34-5Approved|InvestigationalTarget
DB08864RilpivirineSmall Molecule500287-72-9ApprovedTarget
DB11087Pyrethrum extractSmall MoleculeApprovedTarget
DB11605MyrrhSmall Molecule9000-45-7ApprovedTarget
DB12582PiperineSmall Molecule94-62-2InvestigationalTarget
DB13179TroleandomycinSmall Molecule2751-09-9ApprovedTarget
DB13873Fenofibric acidSmall Molecule42017-89-0ApprovedTarget
DB13952Estradiol acetateSmall Molecule4245-41-4Approved|InvestigationalTarget
DB13953Estradiol benzoateSmall Molecule50-50-0Approved|InvestigationalTarget
DB13954Estradiol cypionateSmall Molecule313-06-4Approved|InvestigationalTarget
DB13955Estradiol dienanthateSmall Molecule7732-97-0Approved|InvestigationalTarget
DB13956Estradiol valerateSmall Molecule979-32-8Approved|InvestigationalTarget
DB14001alpha-Tocopherol succinateSmall Molecule4345-03-3Approved|NutraceuticalTarget
DB14002D-alpha-Tocopherol acetateSmall Molecule58-95-7Approved|NutraceuticalTarget
ID Drug Name Action PubMed
C06571910-hydroxywarfarin10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein20735727
C06571910-hydroxywarfarin[10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP2C9 mRNA20735727
C06571910-hydroxywarfarin[10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA20735727
C5171131,1-bis(4-hydroxyphenyl)cyclohexane"1,1-bis(4-hydroxyphenyl)cyclohexane binds to and results in increased activity of NR1I2 protein"20869355
C5720521-((2-methylbenzofuran-3-yl)methyl)-3-(thiophen-2-ylmethyl)urea1-((2-methylbenzofuran-3-yl)methyl)-3-(thiophen-2-ylmethyl)urea results in increased activity of NR1I2 protein26187274
C0150681-(3-chlorophenyl)piperazine1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
C0150681-(3-chlorophenyl)piperazine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
C03133813-cis-retinal13-cis-retinal promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I2 protein"23899473|2618727
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I2 protein"23850985
C1067461,5-benzothiazepine"[1,5-benzothiazepine analog co-treated with RXRA] results in increased activity of NR1I2 protein"21315811
C1067461,5-benzothiazepine"1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]"21315811
C00136317 alpha-hydroperoxypregnenolone17 alpha-hydroperoxypregnenolone binds to and results in increased activity of NR1I2 protein16054614
C5203221-methyl-2-phenylindole1-methyl-2-phenylindole binds to and results in increased activity of NR1I2 protein20869355
C0293501-naphthol1-naphthol results in increased activity of NR1I2 protein27665777
C0549192,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased activity of NR1I2 protein"25542188
C0549172,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid"2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid results in increased activity of NR1I2 protein"25542188
C5411312,2',3,3',4,4',5-heptachlorobiphenyl"2,2',3,3',4,4',5-heptachlorobiphenyl results in increased activity of NR1I2 protein"25680588
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl binds to and results in increased activity of NR1I2 protein"20024649
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased activity of NR1I2 protein"24812009
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of NR1I2 mRNA"22664347
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of NR1I2 mRNA"23770461
C0297902,2',3',4,4',5-hexachlorobiphenyl"NR1I2 gene mutant form inhibits the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP2B1 protein]"23770461
C0297902,2',3',4,4',5-hexachlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of CYP2B1 mRNA]"23770461
C0666752,2',3,5,5',6-hexachlorobiphenyl"2,2',3,5,5',6-hexachlorobiphenyl results in increased activity of NR1I2 protein"24812009|2568058
C4776942,2',4,4',5-brominated diphenyl ether"2,2',4,4',5-brominated diphenyl ether results in increased activity of NR1I2 protein"25680588
C4776942,2',4,4',5-brominated diphenyl ether"[2,2',4,4'-tetrabromodiphenyl ether co-treated with 2,2',4,4',5-brominated diphenyl ether co-treated with pentabrominated diphenyl ether 100 co-treated with hexabrominated diphenyl ether 153 co-treated with hexabromodiphenyl ether 154] results in increased activity of NR1I2 protein"25680588
C5112952,2',4,4'-tetrabromodiphenyl ether"[2,2',4,4'-tetrabromodiphenyl ether co-treated with 2,2',4,4',5-brominated diphenyl ether co-treated with pentabrominated diphenyl ether 100 co-treated with hexabrominated diphenyl ether 153 co-treated with hexabromodiphenyl ether 154] results in increased activity of NR1I2 protein"25680588
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased activity of NR1I2 protein"17324954|2421815
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased activity of NR1I2 protein"17324954
C5112952,2',4,4'-tetrabromodiphenyl ether"NR1I2 protein promotes the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP2B10 mRNA]"17324954
C5112952,2',4,4'-tetrabromodiphenyl ether"NR1I2 protein promotes the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP3A11 mRNA]"17324954
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane binds to and results in increased activity of NR1I2 protein"20869355
C0024622,2-di(4-methacryloxyphenyl)propane"2,2-di(4-methacryloxyphenyl)propane binds to and results in increased activity of NR1I2 protein"20869355
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl binds to and results in increased activity of NR1I2 protein"16054614
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl results in increased activity of NR1I2 protein"15885729|2568058
C4898272,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate"2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate binds to and results in increased activity of NR1I2 protein"21115097
C4898272,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate"2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate binds to and results in increased activity of NR1I2 protein"21115097
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased activity of NR1I2 protein"15885729
C0359762,4,2',4'-tetrachlorobiphenyl"2,4,2',4'-tetrachlorobiphenyl results in increased activity of NR1I2 protein"25680588
C0817662,4,4'-trichlorobiphenyl"2,4,4'-trichlorobiphenyl results in increased expression of NR1I2 mRNA"23770461
C0817662,4,4'-trichlorobiphenyl"NR1I2 gene mutant form inhibits the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP2B1 protein]"23770461
C0817662,4,4'-trichlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP2B1 mRNA]"23770461
C0817662,4,4'-trichlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,4,4'-trichlorobiphenyl results in increased expression of CYP3A23/3A1 mRNA]"23770461
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl binds to and results in increased activity of NR1I2 protein"16054614
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of NR1I2 protein"15885729|2568058
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of NR1I2 mRNA"22664347
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of NR1I2 mRNA"23770461
C0140242,4,5,2',4',5'-hexachlorobiphenyl"NR1I2 gene mutant form inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 protein]"23770461
C0140242,4,5,2',4',5'-hexachlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 mRNA]"23770461
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of NR1I2 protein"25680588
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl binds to and results in increased activity of NR1I2 protein"20024649
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl results in increased activity of NR1I2 protein"25680588
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl results in increased expression of NR1I2 mRNA"23770461
C0098282,4,5,2',5'-pentachlorobiphenyl"NR1I2 gene mutant form inhibits the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP2B1 protein]"23770461
C0098282,4,5,2',5'-pentachlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP2B1 mRNA]"23770461
C0104222,4,6-trichlorophenyl 4-nitrophenyl ether"2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of NR1I2 protein"21115097
C0104222,4,6-trichlorophenyl 4-nitrophenyl ether"2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of NR1I2 protein"21115097
C56225124-norcholan-2,3,24-tryl-2,3,23-sulfuric acid"24-norcholan-2,3,24-tryl-2,3,23-sulfuric acid binds to and results in increased activity of NR1I2 protein"21141967
C0094072,5,2',5'-tetrachlorobiphenyl"2,5,2',5'-tetrachlorobiphenyl results in increased expression of NR1I2 mRNA"23770461
C0094072,5,2',5'-tetrachlorobiphenyl"NR1I2 gene mutant form inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP2B1 protein]"23770461
C0094072,5,2',5'-tetrachlorobiphenyl"NR1I2 gene mutant form promotes the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP2B1 mRNA]"23770461
C0149532-acetyltributylcitrate2-acetyltributylcitrate results in increased activity of NR1I2 protein21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate promotes the reaction [NCOA1 protein binds to NR1I2 protein]21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate promotes the reaction [NCOA2 protein binds to NR1I2 protein]21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate results in increased activity of NR1I2 protein21742782
C0149532-acetyltributylcitrateNR1I2 protein affects the reaction [2-acetyltributylcitrate results in increased expression of CYP3A4 mRNA]21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate results in increased activity of NR1I2 protein21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate results in increased activity of NR1I2 protein21742782
C0149532-acetyltributylcitrate2-acetyltributylcitrate results in increased activity of NR1I2 protein21742782
C5762612-ethylhexyl 2,3,4,5-tetrabromobenzoate"2-ethylhexyl 2,3,4,5-tetrabromobenzoate metabolite results in increased activity of NR1I2 protein"27506419
C5762612-ethylhexyl 2,3,4,5-tetrabromobenzoate"2-ethylhexyl 2,3,4,5-tetrabromobenzoate results in increased activity of NR1I2 protein"27506419
C5422232-phenylindole2-phenylindole binds to and results in increased activity of NR1I2 protein20869355
C0043692-phenylphenol2-phenylphenol binds to and results in increased activity of NR1I2 protein21115097
C0106423,3',5-triiodothyroacetic acid"3,3',5-triiodothyroacetic acid results in increased activity of NR1I2 protein"25455453
C0106423,3',5-triiodothyroacetic acid"[3,3',5-triiodothyroacetic acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"25455453
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in increased activity of NR1I2 protein"25542144
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA"25542144
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"25542144
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of NR1I2 mRNA]"19467301
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I2 mRNA"25424564
C0230353,4,5,3',4'-pentachlorobiphenyl"AHR2 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NR1I2 mRNA]"25424564
C0168343,5-xylenol"3,5-xylenol analog results in increased activity of NR1I2 protein"27665777
C0414773-hydroxyflavone3-hydroxyflavone binds to and results in increased activity of NR1I2 protein26238175
C0414773-hydroxyflavone3-hydroxyflavone promotes the reaction [NCOA1 protein binds to NR1I2 protein]26238175
C0414773-hydroxyflavone3-hydroxyflavone promotes the reaction [NCOA2 protein binds to NR1I2 protein]26238175
C0414773-hydroxyflavone3-hydroxyflavone promotes the reaction [NCOA3 protein binds to NR1I2 protein]26238175
C0414773-hydroxyflavone3-hydroxyflavone results in increased activity of NR1I2 protein26238175
C0414773-hydroxyflavone3-hydroxyflavone results in increased activity of NR1I2 protein26238175
C4558603-ketolithocholic acid3-ketolithocholic acid binds to and results in increased activity of NR1I2 protein15489543
C0473683-methylquercetin3-methylquercetin binds to and results in increased activity of NR1I2 protein26238175
C0473683-methylquercetin3-methylquercetin results in increased activity of NR1I2 protein26238175
C0462303-oxocholan-24-oic acid3-oxocholan-24-oic acid results in increased activity of NR1I2 protein15708356
C4171904-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine"4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine binds to and results in increased activity of NR1I2 protein"15673846
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of NR1I2 mRNA"18648102
C5310564,5,6,7-tetrachlorophthalide"4,5,6,7-tetrachlorophthalide binds to and results in increased activity of NR1I2 protein"21115097
C5162844-cumylphenol4-cumylphenol binds to and results in increased activity of NR1I2 protein20869355
C5162844-cumylphenol4-cumylphenol promotes the reaction [bisphenol A results in increased activity of NR1I2 protein]22214767
C5162844-cumylphenol4-cumylphenol promotes the reaction [bisphenol B results in increased activity of NR1I2 protein]22214767
C5162844-cumylphenol4-cumylphenol results in increased activity of NR1I2 protein22214767
C5162844-cumylphenolbisphenol A promotes the reaction [4-cumylphenol results in increased activity of NR1I2 protein]22214767
C5162844-cumylphenolbisphenol B promotes the reaction [4-cumylphenol results in increased activity of NR1I2 protein]22214767
C0598534'-hydroxywarfarin4'-hydroxywarfarin binds to and results in increased activity of NR1I2 protein20735727
C0598534'-hydroxywarfarin[4'-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP2C9 mRNA20735727
C0598534'-hydroxywarfarin[4'-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA20735727
C0415944-nonylphenol4-nonylphenol binds to and results in increased activity of NR1I2 protein20869355
C0415944-nonylphenol4-nonylphenol binds to NR1I2 protein15792627
C0415944-nonylphenol4-nonylphenol promotes the reaction [NR1I2 protein results in increased expression of CYP3A23/3A1 mRNA]17483497
C0415944-nonylphenol4-nonylphenol results in increased activity of NR1I2 protein17483497|2568058
C0415944-nonylphenol4-nonylphenol promotes the reaction [NR1I2 protein results in increased expression of CYP3A23/3A1 mRNA]17483497
C0415944-nonylphenol4-nonylphenol results in increased activity of NR1I2 protein17483497
C0415944-nonylphenol4-nonylphenol binds to NR1I2 protein15792627
C0415944-nonylphenol4-nonylphenol results in increased activity of NR1I2 protein25680588
C0415944-nonylphenol4-nonylphenol results in increased activity of NR1I2 protein16013040
C0804174-octylphenol4-octylphenol affects the activity of NR1I2 protein20024649
C0124385-p-methylphenyl-5-phenylhydantoin5-p-methylphenyl-5-phenylhydantoin binds to and results in increased activity of NR1I2 protein15039302
C4750936-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime"6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I2 protein"27732639
C4750936-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime"6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I2 protein"23899473
C4750936-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime"6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I2 protein"16857725
C1118556-formylindolo(3,2-b)carbazole"6-formylindolo(3,2-b)carbazole binds to and results in increased activity of NR1I2 protein"21291553
C0662097-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine"[7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine co-treated with RXRA] results in increased activity of NR1I2 protein"21315811
C0662097-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine"7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]"21315811
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of NR1I2 mRNA"27160211
C0313909-cis-retinal9-cis-retinal promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
C023717acacetinacacetin results in increased activity of NR1I2 protein25455453
D000082AcetaminophenAcetaminophen results in decreased expression of NR1I2 mRNA21420995|2906747
D000082AcetaminophenAcetaminophen results in decreased expression of NR1I2 protein29067470
D000082AcetaminophenNR1I2 protein affects the reaction [CYP3A4 protein results in increased metabolism of Acetaminophen]19460945
D000082AcetaminophenAcetaminophen affects the expression of NR1I2 mRNA17562736
D000082AcetaminophenGHRHR protein affects the reaction [NR1I2 protein affects the susceptibility to Acetaminophen]17521389
D000082AcetaminophenNR1I2 gene mutant form results in decreased uptake of Acetaminophen16141365
D000082AcetaminophenNR1I2 protein affects the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]16141365
D000082AcetaminophenNR1I2 protein affects the susceptibility to Acetaminophen17521389
D000082AcetaminophenNR1I2 protein results in increased susceptibility to Acetaminophen16141365
C473838acetyl triethyl citrateacetyl triethyl citrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21742782
C473838acetyl triethyl citrateacetyl triethyl citrate results in increased activity of NR1I2 protein21742782
C064882acifluorfen-methylacifluorfen-methyl binds to and results in increased activity of NR1I2 protein21115097
C064882acifluorfen-methylacifluorfen-methyl binds to and results in increased activity of NR1I2 protein21115097
C084829adiphenineadiphenine results in increased activity of NR1I2 protein25455453
C016601afimoxifeneafimoxifene binds to and results in increased activity of NR1I2 protein16054614
C016601afimoxifeneafimoxifene results in increased activity of NR1I2 protein15885729
D016604Aflatoxin B1Aflatoxin B1 affects the expression of NR1I2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]21641981
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of NR1I2 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of NR1I2 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased activity of NR1I2 protein21641981
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of NR1I2 mRNA21994236
C027955aflatoxin G1aflatoxin G1 promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]21641981
C027955aflatoxin G1aflatoxin G1 results in increased activity of NR1I2 protein21641981
D016607Aflatoxin M1Aflatoxin M1 promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]21641981
D016607Aflatoxin M1Aflatoxin M1 results in increased activity of NR1I2 protein21641981
C000188alachloralachlor binds to and results in increased activity of NR1I2 protein21115097
C000188alachloralachlor results in increased activity of NR1I2 protein16565514
C000188alachloralachlor binds to and results in increased activity of NR1I2 protein21115097
C000188alachloralachlor binds to and results in increased activity of NR1I2 protein14613717
C000188alachloralachlor binds to and results in increased activity of NR1I2 protein16054614
D000452AldrinAldrin binds to and results in increased activity of NR1I2 protein21115097
D000452AldrinAldrin results in increased activity of NR1I2 protein15548381
C103303alitretinoinalitretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
C004471allyl isothiocyanateallyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]25069801
C004471allyl isothiocyanateallyl isothiocyanate binds to and results in decreased activity of NR1I2 protein25069801
D0435825-alpha-Dihydroprogesterone5-alpha-Dihydroprogesterone binds to and results in increased activity of NR1I2 protein21291553
D0435825-alpha-Dihydroprogesterone5-alpha-Dihydroprogesterone binds to and results in increased activity of NR1I2 protein16054614|2129155
D0435825-alpha-Dihydroprogesterone5-alpha-Dihydroprogesterone affects the activity of NR1I2 protein15846226
D0435825-alpha-DihydroprogesteroneNR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with Methacholine Chloride]17159084
D0435825-alpha-DihydroprogesteroneNR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide]17159084
D0435825-alpha-Dihydroprogesterone5-alpha-Dihydroprogesterone binds to and results in increased activity of NR1I2 protein21291553
D013196DihydrotestosteroneDihydrotestosterone binds to and results in increased activity of NR1I2 protein14613717
D013196DihydrotestosteroneDihydrotestosterone binds to and results in increased activity of NR1I2 protein16054614
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein21115097
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in increased activity of NR1I2 protein25680588
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein21115097
D00690717-alpha-Hydroxypregnenolone17-alpha-Hydroxypregnenolone binds to and results in increased activity of NR1I2 protein21291553
C069512alpha-methylepininealpha-methylepinine results in decreased expression of NR1I2 mRNA21871945
C069512alpha-methylepininesulforafan inhibits the reaction [alpha-methylepinine results in decreased expression of NR1I2 mRNA]21871945
D024502alpha-Tocopherolalpha-Tocopherol promotes the reaction [NR1I2 results in increased expression of CPT1A mRNA]17936189
D000577AmidesAmides analog binds to and results in increased activity of NR1I2 protein15872116
D000577AmidesAmides analog binds to and results in increased activity of NR1I2 protein15872116
D000616AminoglutethimideAminoglutethimide results in increased activity of NR1I2 protein21068194
D000638AmiodaroneAmiodarone results in increased expression of NR1I2 mRNA24489787
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NR1I2 mRNA16483693
D000661AmphetamineAmphetamine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
D000661Amphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Amphetamine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
C095108amprenavirNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]18799805
C003530androst-16-en-3-olandrost-16-en-3-ol binds to and results in increased activity of NR1I2 protein21291553
C034744androst-5-en-3-olandrost-5-en-3-ol binds to and results in increased activity of NR1I2 protein21291553
C000658androstan-3-olandrostan-3-ol promotes the reaction [NR1I2 protein binds to NCOA1 protein]15833898
D000732AndrostanolsAndrostanols binds to and results in increased activity of NR1I2 protein16054614|2086935
D000732AndrostanolsAndrostanols binds to and results in increased activity of NR1I2 protein16054614
C435690anilofosanilofos binds to and results in increased activity of NR1I2 protein21115097
C435690anilofosanilofos binds to and results in increased activity of NR1I2 protein21115097
D001032ApazoneApazone results in increased activity of NR1I2 protein25455453
D047310ApigeninApigenin results in increased activity of NR1I2 protein25455453
C026987aroclor 1260aroclor 1260 results in increased activity of NR1I2 protein24812009
C026987aroclor 1260NR1I2 gene mutant form results in increased susceptibility to aroclor 126026612838
C015001arsenitearsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]22159698
C031327artemisinineartemisinine binds to and results in increased activity of NR1I2 protein15761118
C031327artemisinine[artemisinine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with NR1I2 protein] results in increased expression of G6PC mRNA24204015
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA24204015
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of NR1I2 protein26616219
D000069059Atorvastatin CalciumNR1I2 protein promotes the reaction [Atorvastatin Calcium results in decreased expression of GCK protein]26616219
D000069059Atorvastatin CalciumNR1I2 protein promotes the reaction [Atorvastatin Calcium results in decreased expression of SLC2A2 protein]26616219
D000069059Atorvastatin CalciumAtorvastatin Calcium binds to and results in increased activity of NR1I2 protein15986414
D000069059Atorvastatin CalciumAtorvastatin Calcium promotes the reaction [Dietary Fats results in increased expression of NR1I2 protein]26616219
D001393AzolesAzoles affects the activity of NR1I2 protein21333771
D001393Azoles[Azoles affects the activity of NR1I2 protein] which affects the expression of CYP3A421333771
D001507BeclomethasoneBeclomethasone results in increased activity of NR1I2 protein21068194
C005947benefinbenefin results in increased activity of NR1I2 protein20143881
C480688benfuresatebenfuresate binds to and results in increased activity of NR1I2 protein21115097
C061004benidipinebenidipine results in increased activity of NR1I2 protein27732883
C005298benoxinatebenoxinate results in increased activity of NR1I2 protein25455453
C001847bensulidebensulide results in increased activity of NR1I2 protein20143881
C037925benthiocarbbenthiocarb binds to and results in increased activity of NR1I2 protein21115097
C037925benthiocarbbenthiocarb binds to and results in increased activity of NR1I2 protein21115097
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein"23845848
C017228benzo(a)pyrene 7,8-dihydrodiol"[benzo(a)pyrene 7,8-dihydrodiol binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"23845848
C002615benzo(c)phenanthrenebenzo(c)phenanthrene binds to and results in increased activity of NR1I2 protein23845848
C002615benzo(c)phenanthrene[benzo(c)phenanthrene binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA23845848
C026153benzo(c)phenanthrene 3,4-dihydrodiol"benzo(c)phenanthrene 3,4-dihydrodiol binds to and results in increased activity of NR1I2 protein"23845848
C026153benzo(c)phenanthrene 3,4-dihydrodiol"[benzo(c)phenanthrene 3,4-dihydrodiol binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"23845848
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of NR1I2 protein25680588
D019324beta-NaphthoflavoneNR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]28428138
D019324beta-NaphthoflavonePregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]28428138
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of NR1I2 mRNA20607812
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of NR1I2 protein25680588
C047723benzophenonebenzophenone binds to and results in increased activity of NR1I2 protein14613717
C047723benzophenonebenzophenone binds to and results in increased activity of NR1I2 protein16054614
D001564Benzo(a)pyreneBenzo(a)pyrene binds to and results in increased activity of NR1I2 protein23845848
D001564Benzo(a)pyrene[Benzo(a)pyrene binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA23845848
D001564Benzo(a)pyreneNR1I2 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of AHR mRNA]28428138
D001564Benzo(a)pyreneNR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]28428138
D001564Benzo(a)pyreneNR1I2 protein results in decreased susceptibility to Benzo(a)pyrene18381355
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to and results in increased activity of NR1I2 protein"23845848
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"[7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"23845848
D001599BerberineBerberine results in increased activity of NR1I2 protein21524698
D001599Berberine[Berberine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA21524698
C068337bergamottinbergamottin results in increased activity of NR1I2 protein21924250
D019207beta Carotenebeta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
D019207beta Carotenebeta Carotene results in increased activity of NR1I2 protein15949683
D004958EstradiolEstradiol binds to and results in increased activity of NR1I2 protein16054614|2222339
D004958EstradiolEstradiol promotes the reaction [NR1I2 protein binds to MED1 protein]15650019
D004958EstradiolEstradiol promotes the reaction [NR1I2 protein binds to NCOA1 protein]15650019
D004958EstradiolEstradiol results in increased activity of NR1I2 protein15650019
D004958EstradiolEstradiol binds to and results in increased activity of NR1I2 protein16054614
D004958EstradiolEstradiol binds to and results in increased activity of NR1I2 protein21291553
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein21115097
D001629BezafibrateBezafibrate binds to and results in increased activity of NR1I2 protein20024649
C050421bifenoxbifenox binds to and results in increased activity of NR1I2 protein21115097
C050421bifenoxbifenox binds to and results in increased activity of NR1I2 protein21115097
C099952bifenthrinbifenthrin results in increased activity of NR1I2 protein19249324
C099952bifenthrinbifenthrin results in increased activity of NR1I2 protein19249324
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of NR1I2 protein15718292
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of NR1I2 protein15718292
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of NR1I2 protein15718292
D001647Bile Acids and SaltsNR1I2 protein affects the chemical synthesis of Bile Acids and Salts15684063
D001647Bile Acids and SaltsNR1I2 protein affects the susceptibility to Bile Acids and Salts15619241
D001647Bile Acids and SaltsNR1I2 protein results in decreased susceptibility to Bile Acids and Salts15684063
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of NR1I2 protein15718292
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of NR1I2 protein15718292
D001647Bile Acids and SaltsNR1I2 protein results in increased metabolism of Bile Acids and Salts15725701
D001663BilirubinBilirubin results in increased expression of NR1I2 mRNA18706437
D001663BilirubinNR1I2 protein affects the abundance of Bilirubin15726644
D001663BilirubinNR1I2 protein affects the transport of Bilirubin15726644
C018465bioallethrinbioallethrin results in increased activity of NR1I2 protein19249324
C018465bioallethrinbioallethrin results in increased activity of NR1I2 protein19249324
C002842bioresmethrinbioresmethrin results in increased activity of NR1I2 protein19249324
C002842bioresmethrinbioresmethrin results in increased activity of NR1I2 protein19249324
C576262bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate"bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate binds to and results in increased activity of NR1I2 protein"27506419
C576262bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate"bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate inhibits the reaction [rifaximin results in increased activity of NR1I2 protein]"27506419
C576262bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate"bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate metabolite binds to and results in increased activity of NR1I2 protein"27506419
C000595304bis(2-propylheptyl)phthalatebis(2-propylheptyl)phthalate results in increased activity of NR1I2 protein27551952
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone binds to and results in decreased activity of NR1I2 protein20869355
C006780bisphenol Abisphenol A affects the expression of NR1I2 mRNA25038724
C006780bisphenol A4-cumylphenol promotes the reaction [bisphenol A results in increased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A affects the activity of NR1I2 protein20024649
C006780bisphenol Abisphenol A analog results in increased activity of NR1I2 protein22214767
C006780bisphenol Abisphenol A binds to and results in increased activity of NR1I2 protein16054614|2086935
C006780bisphenol Abisphenol A inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A promotes the reaction [4-cumylphenol results in increased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]22214767
C006780bisphenol Abisphenol A promotes the reaction [NCOA1 protein binds to NR1I2 protein]11581012
C006780bisphenol Abisphenol A promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]11581012
C006780bisphenol Abisphenol A results in increased activity of NR1I2 protein15650019|2122790
C006780bisphenol A[bisphenol A results in increased activity of NR1I2 protein] which results in increased expression of ABCB1A mRNA24755147
C006780bisphenol A[bisphenol A results in increased activity of NR1I2 protein] which results in increased expression of CD36 mRNA24755147
C006780bisphenol A[bisphenol A results in increased activity of NR1I2 protein] which results in increased expression of CYP3A11 mRNA24755147
C006780bisphenol ANR1I2 protein results in increased susceptibility to bisphenol A27177772
C006780bisphenol ANR1I2 protein results in increased susceptibility to bisphenol A24755147
C006780bisphenol Abisphenol A results in decreased expression of NR1I2 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of NR1I2 protein24552547
C006780bisphenol Abisphenol A results in increased activity of NR1I2 protein25680588
C492482bisphenol B4-cumylphenol promotes the reaction [bisphenol B results in increased activity of NR1I2 protein]22214767
C492482bisphenol Bbisphenol B promotes the reaction [4-cumylphenol results in increased activity of NR1I2 protein]22214767
C492482bisphenol Bbisphenol B results in increased activity of NR1I2 protein22214767
C083642bitertanolbitertanol binds to and results in increased activity of NR1I2 protein21115097
C083642bitertanolbitertanol binds to and results in increased activity of NR1I2 protein21115097
D020126Brefeldin ABrefeldin A results in decreased expression of NR1I2 mRNA25616597
D001962Bromcresol PurpleBromcresol Purple binds to and results in decreased activity of NR1I2 protein20869355
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR1I2 mRNA22079614
C006820bromperidolbromperidol results in increased activity of NR1I2 protein25455453
D001979Bromthymol BlueBromthymol Blue binds to and results in increased activity of NR1I2 protein20869355
D019819BudesonideBudesonide results in increased activity of NR1I2 protein25455453
D019819Budesonide[Budesonide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D019819BudesonideBudesonide results in increased expression of NR1I2 mRNA19562681
C071704bupirimatebupirimate results in increased activity of NR1I2 protein16565514|2192425
D002065BuspironeBuspirone results in increased expression of NR1I2 mRNA24136188
C487162butafenacilbutafenacil results in increased activity of NR1I2 protein22206814
C004605butambenbutamben binds to and results in increased activity of NR1I2 protein21291553
C549110butamifosbutamifos binds to and results in increased activity of NR1I2 protein21115097
C549110butamifosbutamifos metabolite binds to and results in increased activity of NR1I2 protein21115097
C549110butamifosbutamifos binds to and results in increased activity of NR1I2 protein21115097
C549110butamifosbutamifos metabolite binds to and results in increased activity of NR1I2 protein21115097
C017125butoconazolebutoconazole results in increased activity of NR1I2 protein25455453
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of NR1I2 mRNA17627975
C027561butylbenzyl phthalatebutylbenzyl phthalate results in increased activity of NR1I2 protein27551952
C444649cafenstrolecafenstrole binds to and results in increased activity of NR1I2 protein21115097
D002215Captan"[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein"25028461
D002220CarbamazepineCarbamazepine binds to and results in increased activity of NR1I2 protein14977870
D002220CarbamazepineCarbamazepine results in increased activity of NR1I2 protein12065438|1711280
D002220CarbamazepineCarbamazepine results in increased expression of NR1I2 mRNA17112801
D002220CarbamazepineCarbamazepine results in increased expression of NR1I2 protein18473823
D002220Carbamazepine[Carbamazepine binds to NR1I2 protein] which results in increased expression of CYP3A415371980
C012227carbamazepine epoxidecarbamazepine epoxide results in increased activity of NR1I2 protein17112801
D012721CarbarylCarbaryl results in increased expression of NR1I2 mRNA22310298
D012721CarbarylCarbaryl results in increased activity of NR1I2 protein27665777
C086276cerivastatincerivastatin results in increased activity of NR1I2 protein15802384
D002635Chenodeoxycholic AcidChenodeoxycholic Acid analog binds to and results in increased activity of NR1I2 protein17963371
D002635Chenodeoxycholic AcidChenodeoxycholic Acid binds to and results in increased activity of NR1I2 protein17963371
D002635Chenodeoxycholic AcidChenodeoxycholic Acid metabolite results in increased activity of NR1I2 protein27871908
D002635Chenodeoxycholic AcidChenodeoxycholic Acid binds to and results in increased activity of NR1I2 protein21291553
C473711Chir 99021Chir 99021 binds to and results in increased activity of NR1I2 protein26259606
D002706ChlordanChlordan binds to and results in increased activity of NR1I2 protein16054614|2111509
D002706ChlordanChlordan promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]12417264
D002706ChlordanChlordan results in increased activity of NR1I2 protein12417264|1554838
D002706ChlordanChlordan binds to and results in increased activity of NR1I2 protein21115097
D002706ChlordanNR1I2 affects the susceptibility to Chlordan20403969
D002706ChlordanChlordan binds to and results in increased activity of NR1I2 protein16054614
D002706ChlordanChlordan results in increased activity of NR1I2 protein25680588
D007631ChlordeconeChlordecone binds to and results in increased activity of NR1I2 protein16054614
D007631ChlordeconeChlordecone results in increased activity of NR1I2 protein15548381
D002709Chlorfenvinphos[Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein25028461
C054410chlormethoxynilchlormethoxynil binds to and results in increased activity of NR1I2 protein21115097
C054410chlormethoxynilchlormethoxynil binds to and results in increased activity of NR1I2 protein21115097
C004659chlorobenzilatechlorobenzilate binds to and results in increased activity of NR1I2 protein21115097
C004659chlorobenzilatechlorobenzilate binds to and results in increased activity of NR1I2 protein21115097
C004663chloropropylatechloropropylate binds to and results in increased activity of NR1I2 protein21115097
C004663chloropropylatechloropropylate binds to and results in increased activity of NR1I2 protein21115097
D002746ChlorpromazineChlorpromazine analog results in increased expression of NR1I2 mRNA15924885
D002746Chlorpromazine[Chlorpromazine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D002748ChlorprophamChlorpropham binds to and results in increased activity of NR1I2 protein21115097
D002748Chlorpropham[Maleic Hydrazide co-treated with Chlorpropham] results in increased activity of NR1I2 protein25028461
D004390ChlorpyrifosChlorpyrifos binds to and results in increased activity of NR1I2 protein16054614|2111509
D004390ChlorpyrifosChlorpyrifos results in increased activity of NR1I2 protein15548381
D004390ChlorpyrifosChlorpyrifos binds to and results in increased activity of NR1I2 protein21115097
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein"21141967
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"cholan-2,3,24-tryl-2,3,24-trisulfate results in increased expression of NR1I2 mRNA"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]"21599020
C561233cholan-2,3,24-tryl-2,3,24-trisulfate"cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein"21599020
D002777CholestanolsCholestanols results in increased activity of NR1I2 protein15718292
D002777CholestanolsCholestanols results in increased activity of NR1I2 protein15718292
D002777CholestanolsCholestanols results in increased activity of NR1I2 protein15718292
D002777CholestanolsCholestanols results in increased activity of NR1I2 protein15718292
D002777CholestanolsCholestanols results in increased activity of NR1I2 protein15718292
D002784CholesterolNR1I2 protein affects the metabolism of Cholesterol15684063
D002784CholesterolNR1I2 protein affects the metabolism of and results in decreased activity of and results in decreased susceptibility to Cholesterol15710871
D002791Cholesterol, Dietary"NR1I2 protein results in decreased susceptibility to Cholesterol, Dietary metabolite"15671183
D019826Cholic AcidCholic Acid metabolite results in increased activity of NR1I2 protein27871908
D019826Cholic AcidCholic Acid results in increased activity of NR1I2 protein27871908
D019826Cholic AcidCholic Acid results in increased expression of NR1I2 mRNA25582706
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of NR1I2 mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR1I2 mRNA18488193
D002922CiguatoxinsCiguatoxins affects the expression of NR1I2 mRNA18353800
D002927CimetidineCimetidine results in decreased expression of NR1I2 protein22733800
D002927Cimetidine[Monocrotophos co-treated with Cimetidine] results in increased expression of NR1I2 protein22733800
D002990ClobetasolClobetasol results in increased activity of NR1I2 protein25455453
D002990Clobetasol[Clobetasol results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D002994ClofibrateClofibrate results in increased expression of NR1I2 mRNA17627975
D002994ClofibrateClofibrate results in decreased expression of NR1I2 mRNA20607812
D002994ClofibrateClofibrate results in increased expression of NR1I2 protein15826607
D002994ClofibrateDactinomycin inhibits the reaction [Clofibrate results in increased expression of NR1I2 protein]15826607
D002996ClomipheneClomiphene results in increased activity of NR1I2 protein25455453
D002996Clomiphene[Clomiphene results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D002998ClonazepamClonazepam binds to and results in increased activity of NR1I2 protein20024649
D003010ClorgylineClorgyline results in increased activity of NR1I2 protein25455453
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein27732639
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein28259787
D003022ClotrimazoleClotrimazole binds to and results in increased activity of NR1I2 protein14977870|1584971
D003022ClotrimazoleClotrimazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]17998298
D003022ClotrimazoleClotrimazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein12065438|1554838
D003022ClotrimazoleClotrimazole results in increased expression of NR1I2 mRNA17998298
D003022ClotrimazoleDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]12695351
D003022ClotrimazoleNR1I2 protein affects the reaction [Clotrimazole results in increased expression of and results in increased activity of CYP2B6 protein]12695351
D003022ClotrimazoleNR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]12695351
D003022ClotrimazoleNR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP3A4 mRNA]27507784
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein12049174|1691904
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein23899473|2773263
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein25680588
D003022ClotrimazoleClotrimazole results in increased activity of NR1I2 protein11836020
D003024ClozapineClozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
D003024Clozapine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D005576ColforsinColforsin results in increased activity of NR1I2 protein27732639
D005576ColforsinColforsin results in increased activity of NR1I2 protein27732639
D005576ColforsinColforsin results in increased expression of NR1I2 mRNA20211155
D005576Colforsintributyltin inhibits the reaction [Colforsin results in increased expression of NR1I2 mRNA]20211155
D019327Copper SulfateCopper Sulfate results in increased expression of NR1I2 mRNA19549813
D003345CorticosteroneCorticosterone binds to and results in increased activity of NR1I2 protein16054614
D003345CorticosteroneCorticosterone promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]11581012
D003345CorticosteroneCorticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]12072427
D003345CorticosteroneKetoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]12072427
D003345CorticosteroneCorticosterone binds to and results in increased activity of NR1I2 protein16054614
D003348CortisoneCortisone binds to and results in increased activity of NR1I2 protein21291553
C037886cryptotanshinonecryptotanshinone results in increased activity of NR1I2 protein18805405
C029892cupric chloridecupric chloride results in increased expression of NR1I2 protein19616320
D003471CuprizoneCuprizone results in increased expression of NR1I2 mRNA26577399
D003474CurcuminCurcumin results in increased activity of NR1I2 protein17210444
C002488cyanophenphoscyanophenphos binds to and results in increased activity of NR1I2 protein21115097
C002488cyanophenphoscyanophenphos binds to and results in increased activity of NR1I2 protein21115097
D003520CyclophosphamideCyclophosphamide binds to and results in increased activity of NR1I2 protein18839173
D003520CyclophosphamideCyclophosphamide results in increased activity of NR1I2 protein20041327
D003520Cyclophosphamide[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
D003520Cyclophosphamide[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D003520CyclophosphamideNR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]20041327
D016572CyclosporineCyclosporine affects the expression of NR1I2 mRNA24973091
D016572CyclosporineCyclosporine results in decreased expression of NR1I2 mRNA20106945
D016572CyclosporineCyclosporine results in increased expression of NR1I2 mRNA25562108|2798913
D016572CyclosporineCyclosporine results in decreased expression of NR1I2 mRNA19770486
C052570cyfluthrincyfluthrin binds to and results in increased activity of NR1I2 protein21115097
C052570cyfluthrincyfluthrin results in increased activity of NR1I2 protein19249324|2220681
C052570cyfluthrincyfluthrin results in increased activity of NR1I2 protein polymorphism19249324
C052570cyfluthrincyfluthrin binds to and results in increased activity of NR1I2 protein21115097
C052570cyfluthrincyfluthrin results in increased activity of NR1I2 protein19249324
C037304cyhalothrinCES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein]19249324
C037304cyhalothrincyhalothrin binds to and results in increased activity of NR1I2 protein21115097
C037304cyhalothrincyhalothrin results in increased activity of NR1I2 protein19249324
C037304cyhalothrincyhalothrin results in increased activity of NR1I2 protein polymorphism19249324
C037304cyhalothrin[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein25028461
C037304cyhalothrincyhalothrin binds to and results in increased activity of NR1I2 protein21115097
C037304cyhalothrincyhalothrin results in increased activity of NR1I2 protein19249324
C017160cypermethrincypermethrin binds to and results in increased activity of NR1I2 protein16054614|2111509
C017160cypermethrincypermethrin results in increased activity of NR1I2 protein15548381|2220681
C017160cypermethrincypermethrin results in increased expression of NR1I2 mRNA22310298
C017160cypermethrincypermethrin binds to and results in increased activity of NR1I2 protein21115097
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of ABCC3 mRNA]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of ABCC3 protein]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of AHR mRNA]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of CD36 mRNA]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of CDKN1A mRNA]28058446
C093628cyproconazole[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of CYP2B10 protein]28058446
C093628cyproconazole[NR1I3 protein co-treated with NR1I2 protein] affects the reaction [cyproconazole results in increased expression of CYP2B10 mRNA]28058446
C108338cyprodinil[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein25028461
D017373Cyproterone AcetateCyproterone Acetate binds to and results in increased activity of NR1I2 protein16054614
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein"21115097
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid binds to and results in increased activity of NR1I2 protein"21115097
D003609DactinomycinDactinomycin inhibits the reaction [ochratoxin A results in decreased expression of NR1I2 mRNA]26341324
D003609DactinomycinDactinomycin inhibits the reaction [Clofibrate results in increased expression of NR1I2 protein]15826607
D003609DactinomycinDactinomycin inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]20599767
D003609DactinomycinDactinomycin inhibits the reaction [perfluorodecanoic acid results in increased expression of NR1I2 protein]15826607
C004742daidzeindaidzein binds to and results in increased activity of NR1I2 protein16054614
D003634DDTDDT binds to and results in increased activity of NR1I2 protein16054614|2068633
D003634DDT[DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein25028461
D003634DDTDDT results in increased activity of NR1I2 protein15548381|2568058
D003634DDTDDT results in increased activity of NR1I2 protein25680588
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased activity of NR1I2 protein17324954|2568058
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased activity of NR1I2 protein17324954
C010902decabromobiphenyl etherNR1I2 protein promotes the reaction [decabromobiphenyl ether results in increased expression of CYP2B10 mRNA]17324954
C010902decabromobiphenyl etherNR1I2 protein promotes the reaction [decabromobiphenyl ether results in increased expression of CYP3A11 mRNA]17324954
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of NR1I2 protein20686340
C017180decamethrinCES1 protein inhibits the reaction [decamethrin results in increased activity of NR1I2 protein]19249324
C017180decamethrindecamethrin binds to and results in increased activity of NR1I2 protein21115097
C017180decamethrindecamethrin results in increased activity of NR1I2 protein19249324
C017180decamethrindecamethrin binds to and results in increased activity of NR1I2 protein21115097
C017180decamethrindecamethrin results in increased activity of NR1I2 protein19249324
C114768decamethylcyclopentasiloxanedecamethylcyclopentasiloxane results in increased activity of NR1I2 protein25680588
C014347decitabinedecitabine results in increased expression of NR1I2 mRNA23137910
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of NR1I2 mRNA22713311
D019314Dehydroepiandrosterone SulfateDehydroepiandrosterone Sulfate binds to and results in increased activity of NR1I2 protein21291553
C086916delta-hexachlorocyclohexanedelta-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein21115097
D003840Deoxycholic AcidDeoxycholic Acid metabolite binds to and results in increased activity of NR1I2 protein27871908
D003840Deoxycholic AcidDeoxycholic Acid metabolite promotes the reaction [NR1I2 protein binds to NCOA1 protein]27871908
D003840Deoxycholic AcidDeoxycholic Acid results in increased activity of NR1I2 protein27871908
D003840Deoxycholic AcidDeoxycholic Acid results in increased expression of NR1I2 mRNA25582706
D003840Deoxycholic AcidDeoxycholic Acid binds to and results in increased activity of NR1I2 protein21291553
C010909devrinoldevrinol affects the activity of NR1I2 protein23611293
C010909devrinoldevrinol results in increased activity of NR1I2 protein20143881
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of NR1I2 mRNA]27941970
D003907DexamethasoneDexamethasone binds to and results in increased activity of NR1I2 protein16054614
D003907DexamethasoneDexamethasone binds to NR1I2 protein27071811
D003907DexamethasoneDexamethasone promotes the reaction [NR1I2 protein binds to FGF21 promoter]28088388
D003907DexamethasoneDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Clotrimazole results in increased expression of CYP2B6 mRNA]]]12695351
D003907DexamethasoneDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]]]12695351
D003907DexamethasoneDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]]]12695351
D003907DexamethasoneDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]12695351
D003907DexamethasoneDexamethasone results in increased activity of NR1I2 protein12065438|2164198
D003907DexamethasoneDexamethasone results in increased expression of NR1I2 mRNA19022236
D003907DexamethasoneDexamethasone results in increased expression of NR1I2 protein18332045
D003907DexamethasoneNR1I2 protein affects the reaction [Dexamethasone results in increased expression of FGF21 mRNA]28088388
D003907DexamethasoneDexamethasone binds to and results in increased activity of NR1I2 protein15630458|1591985
D003907DexamethasoneDexamethasone promotes the reaction [NR1I2 protein binds to FGF21 promoter]28088388
D003907DexamethasoneDexamethasone results in increased activity of NR1I2 protein23899473
D003907DexamethasoneNR1I2 affects the reaction [Dexamethasone results in increased activity of CYP3A4 protein]20361990
D003907DexamethasoneNR1I2 protein affects the reaction [Dexamethasone results in increased expression of FGF21 mRNA]28088388
D003907DexamethasoneDexamethasone results in decreased expression of NR1I2 protein20719396
D003907DexamethasoneDactinomycin inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]20599767
D003907DexamethasoneDexamethasone binds to NR1I2 protein19562681
D003907DexamethasoneDexamethasone results in increased activity of NR1I2 protein23439660|2389947
D003907DexamethasoneDexamethasone results in increased expression of NR1I2 mRNA15102944|1956268
D003907DexamethasoneDexamethasone results in increased expression of NR1I2 protein18332045|1847382
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]20599767
D003907DexamethasoneNR1I2 gene mutant form inhibits the reaction [Dexamethasone results in increased expression of CYP3A23/3A1 mRNA]23770461
D003907DexamethasoneNR1I2 protein promotes the reaction [Dexamethasone results in increased expression of CYP3A23/3A1 mRNA]11752103
D003907DexamethasoneTetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of NR1I2 protein]18473823
D003907DexamethasoneDexamethasone binds to and results in increased activity of NR1I2 protein16054614
D003907DexamethasoneDexamethasone binds to and affects the activity of NR1I2 protein15683829
D003907DexamethasoneDexamethasone binds to and results in increased activity of NR1I2 protein18094037
D003907DexamethasoneDexamethasone binds to NR1I2 protein22429928
D003907DexamethasoneDexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]18332045
D003907DexamethasoneDexamethasone promotes the reaction [[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]18332045
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D003907DexamethasoneNR3C1 mRNA affects the reaction [Dexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D003907DexamethasoneNR3C1 protein alternative form inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]20599767
C032201dexamethasone 21-tributylacetatedexamethasone 21-tributylacetate binds to and results in increased activity of NR1I2 protein14977870
C032201dexamethasone 21-tributylacetatedexamethasone 21-tributylacetate results in increased activity of NR1I2 protein12065438
C018038dexamethasone acetatedexamethasone acetate binds to and results in increased activity of NR1I2 protein16054614
D003975DiazepamDiazepam promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
D003975Diazepam"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Diazepam promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene binds to and results in increased activity of NR1I2 protein"23845848
D003992DibucaineDibucaine results in increased activity of NR1I2 protein25455453
D003993Dibutyl PhthalateDibutyl Phthalate binds to and results in increased activity of NR1I2 protein16054614
D003993Dibutyl PhthalateDibutyl Phthalate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21742782
D003993Dibutyl PhthalateDibutyl Phthalate results in increased activity of NR1I2 protein21742782
D003993Dibutyl PhthalateDibutyl Phthalate results in increased activity of NR1I2 protein alternative form21227907
D003993Dibutyl PhthalateDibutyl Phthalate results in increased activity of NR1I2 protein15901914
D003993Dibutyl PhthalateDibutyl Phthalate binds to and results in increased activity of NR1I2 protein16054614
C011445dichlofenthiondichlofenthion binds to and results in increased activity of NR1I2 protein21115097
C011445dichlofenthiondichlofenthion binds to and results in increased activity of NR1I2 protein21115097
D002945CisplatinCisplatin promotes the reaction [NR1I2 protein binds to MED1 protein]15650019
D002945CisplatinCisplatin promotes the reaction [NR1I2 protein binds to NCOA3 protein]15650019
D002945CisplatinCisplatin results in increased activity of NR1I2 protein15650019
D003632DichlorodiphenyldichloroethaneDichlorodiphenyldichloroethane binds to and results in increased activity of NR1I2 protein20686338|2111509
D003632DichlorodiphenyldichloroethaneDichlorodiphenyldichloroethane binds to and results in increased activity of NR1I2 protein21115097
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene binds to and results in increased activity of NR1I2 protein20686338|2111509
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of NR1I2 protein25680588
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of NR1I2 mRNA12869653
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene binds to and results in increased activity of NR1I2 protein16054614
D003633Dichlorodiphenyl Dichloroethylene[Dichlorodiphenyl Dichloroethylene co-treated with Thyroxine] results in increased expression of NR1I2 mRNA16764480
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of NR1I2 mRNA16764480
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of NR1I2 protein25680588
D004008DiclofenacDiclofenac results in increased expression of NR1I2 mRNA19022234
D004009DicloxacillinDicloxacillin results in increased activity of NR1I2 protein25455453
D004010DicofolDicofol binds to and results in increased activity of NR1I2 protein21115097
D004010DicofolDicofol binds to and results in increased activity of NR1I2 protein21115097
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of NR1I2 mRNA26924002
D004026Dieldrin[DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein25028461
D004026DieldrinDieldrin binds to and results in increased activity of NR1I2 protein16054614|2111509
D004026DieldrinDieldrin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]12417264
D004026DieldrinDieldrin results in increased activity of NR1I2 protein12417264|1554838
D004026DieldrinDieldrin binds to and results in increased activity of NR1I2 protein21115097
D004026DieldrinDieldrin results in increased activity of NR1I2 protein12049174
D004026Dieldrin[Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA24615737
D004026Dieldrin[Dieldrin co-treated with RXRA protein co-treated with NR1I2 protein] results in increased expression of PON1 mRNA24615737
D004026DieldrinDieldrin results in increased activity of NR1I2 protein25680588
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of NR1I2 mRNA]"19467301
D004041Dietary FatsDietary Fats results in decreased localization of NR1I2 protein23358370
D004041Dietary FatsDietary Fats results in increased expression of NR1I2 mRNA19467301|2375664
D004041Dietary FatsAtorvastatin Calcium promotes the reaction [Dietary Fats results in increased expression of NR1I2 protein]26616219
D004041Dietary FatsDietary Fats results in increased expression of NR1I2 protein26616219
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate binds to and results in increased activity of NR1I2 protein16054614|2122790
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate binds to NR1I2 protein27071811
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]11581012
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate promotes the reaction [NR1I2 protein results in increased expression of ABCB1 mRNA]17003290
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased activity of NR1I2 protein22206814|2389947
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased activity of NR1I2 protein23899473
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of NR1I2 mRNA17627975
D004051Diethylhexyl Phthalate[Diethylhexyl Phthalate co-treated with Linuron] results in increased expression of NR1I2 mRNA22277248
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased activity of NR1I2 protein23899473
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate binds to and results in increased activity of NR1I2 protein16054614
D004051Diethylhexyl PhthalateDexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]18332045
D004051Diethylhexyl Phthalate[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA18332045
D004051Diethylhexyl PhthalateMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D004051Diethylhexyl PhthalateNR3C1 mRNA affects the reaction [Dexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I2 mRNA18544905
C007379diethyl phthalatediethyl phthalate results in increased activity of NR1I2 protein21227907
D004054DiethylstilbestrolDiethylstilbestrol binds to and results in increased activity of NR1I2 protein16054614
D004132DiflubenzuronDiflubenzuron results in increased activity of NR1I2 protein16565514
D004087DihydroergotamineDihydroergotamine results in increased activity of NR1I2 protein25455453
D002117Calcitriol[Calcitriol co-treated with NR1I2 protein] results in increased expression of CYP24A1 mRNA21115105
D002117CalcitriolCalcitriol results in increased expression of NR1I2 mRNA22687401
D002117CalcitriolCalcitriol results in increased expression of NR1I2 protein22687401
D002117Calcitriol[Calcitriol results in increased expression of NR1I2 protein] which results in increased expression of CYP3A4 mRNA22687401
C025605diisobutyl phthalatediisobutyl phthalate results in increased activity of NR1I2 protein alternative form21227907
C042080diisodecyl phthalatediisodecyl phthalate binds to NR1I2 protein27071811
C012125diisononyl phthalatediisononyl phthalate binds to and results in increased activity of NR1I2 protein21227907
C012125diisononyl phthalatediisononyl phthalate binds to NR1I2 protein27071811
C012125diisononyl phthalatediisononyl phthalate results in increased activity of NR1I2 protein27551952
D004109DilazepDilazep results in increased activity of NR1I2 protein25455453
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of NR1I2 mRNA19084030
C024629dimethyl phthalatedimethyl phthalate affects the expression of NR1I2 mRNA26924002
D004144DiosgeninDiosgenin results in increased activity of NR1I2 protein15611112
D004159Diphenylamine"[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein"25028461
D004206DisopyramideDisopyramide results in increased activity of NR1I2 protein25455453
D004222DisulfotonDisulfoton binds to and results in increased activity of NR1I2 protein21115097
D004237DiuronDiuron binds to and results in increased activity of NR1I2 protein21115097
C067311docetaxeldocetaxel binds to and results in increased activity of NR1I2 protein18839173
C067311docetaxeldocetaxel results in increased activity of NR1I2 protein20041327
C067311docetaxel[docetaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
C067311docetaxelNR1I2 protein promotes the reaction [docetaxel results in increased expression of and results in increased activity of ABCB1 protein]20041327
D004317Doxorubicin[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]20041327
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased activity of NR1I2 protein"16267138|2152469
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal results in increased activity of NR1I2 protein] which results in increased expression of CYP2C9 mRNA"16267138
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA"21524698
D004365Drugs, Chinese Herbal"NR1I2 protein affects the susceptibility to Drugs, Chinese Herbal"16267138
D004365Drugs, Chinese Herbal"NR1I2 protein mutant form affects the susceptibility to Drugs, Chinese Herbal"16267138
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased activity of NR1I2 protein"16267138
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal results in increased activity of NR1I2 protein] which results in increased expression of CYP2C29 mRNA"16267138
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of NR1I2 mRNA"23262642
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased activity of NR1I2 protein"16267138
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA"16267138
D004464EconazoleEconazole binds to and results in increased activity of NR1I2 protein17998298
D004464EconazoleEconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]17998298
D004464EconazoleEconazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
C098320efavirenzefavirenz results in increased activity of NR1I2 protein27732639
C547424EMD 392949EMD 392949 results in decreased expression of NR1I2 mRNA20035846
C547424EMD 392949EMD 392949 results in increased activity of NR1I2 protein20035846
D004726EndosulfanEndosulfan binds to and results in increased activity of NR1I2 protein16054614|2111509
D004726Endosulfan[Endosulfan co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA20361990
D004726Endosulfan[Endosulfan co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA20361990
D004726EndosulfanEndosulfan promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]12417264
D004726EndosulfanEndosulfan results in decreased expression of NR1I2 mRNA28673560
D004726EndosulfanEndosulfan results in increased activity of NR1I2 protein12417264|1554838
D004726EndosulfanEndosulfan binds to and results in increased activity of NR1I2 protein21115097
D004726EndosulfanNR1I2 affects the reaction [Endosulfan results in increased activity of CYP3A4 protein]20361990
D004726EndosulfanNR1I2 affects the reaction [Endosulfan results in increased expression of CYP3A4 protein]20361990
D004726EndosulfanEndosulfan results in increased activity of NR1I2 protein25680588
C544689endosulfan sulfateendosulfan sulfate binds to and results in increased activity of NR1I2 protein21115097
C544689endosulfan sulfate[endosulfan sulfate co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA20361990
C544689endosulfan sulfate[endosulfan sulfate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA20361990
C544689endosulfan sulfateendosulfan sulfate binds to and results in increased activity of NR1I2 protein21115097
D004731EndotoxinsEndotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of NR1I2 mRNA]15456840
D004731EndotoxinsEndotoxins results in decreased expression of NR1I2 mRNA15456840
D004731EndotoxinsEndotoxins results in decreased expression of NR1I2 protein15456840
D004732EndrinEndrin binds to and results in increased activity of NR1I2 protein16054614
D004732EndrinEndrin results in increased activity of NR1I2 protein15548381
D004732EndrinEndrin binds to and results in increased activity of NR1I2 protein21115097
C017435enilconazoleenilconazole binds to and results in increased activity of NR1I2 protein21115097
C017435enilconazole[enilconazole co-treated with methidathion] results in increased activity of NR1I2 protein25028461
C017435enilconazoleenilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
C017435enilconazoleenilconazole results in increased activity of NR1I2 protein16565514
C017435enilconazoleenilconazole binds to and results in increased activity of NR1I2 protein21115097
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride binds to and results in increased activity of NR1I2 protein18839173
D004970EstroneEstrone binds to and results in increased activity of NR1I2 protein21291553
C027392ethafluralinethafluralin results in increased activity of NR1I2 protein20143881
D000431EthanolEthanol affects the localization of NR1I2 protein24853400
D000431EthanolEthanol promotes the reaction [NR1I2 protein binds to CYP3A11 promoter]24853400
D000431EthanolEthanol results in increased expression of NR1I2 mRNA24853400
D004997Ethinyl EstradiolEthinyl Estradiol results in increased activity of NR1I2 protein28259787
D004997Ethinyl EstradiolEthinyl Estradiol binds to and results in increased activity of NR1I2 protein16054614
D004997Ethinyl EstradiolEthinyl Estradiol results in increased activity of NR1I2 protein28259787
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased activity of NR1I2 protein12507762
C100038ethion[Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein25028461
C100038ethionethion binds to and results in increased activity of NR1I2 protein21115097
C100038ethionethion binds to and results in increased activity of NR1I2 protein21115097
C076840ethofenproxethofenprox binds to and results in increased activity of NR1I2 protein21115097
C076840ethofenproxethofenprox binds to and results in increased activity of NR1I2 protein21115097
C474843ethoprophosethoprophos binds to and results in increased activity of NR1I2 protein21115097
C084606ethotoinethotoin binds to and results in increased activity of NR1I2 protein15039302
D005015EthoxyquinEthoxyquin binds to and results in increased activity of NR1I2 protein21115097
D005015EthoxyquinEthoxyquin results in increased activity of NR1I2 protein25455453
D005015EthoxyquinEthoxyquin binds to and results in increased activity of NR1I2 protein21115097
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate binds to and results in increased activity of NR1I2 protein"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate analog binds to and results in increased activity of NR1I2 protein"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate binds to and results in increased activity of NR1I2 protein"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate inhibits the reaction [NCOR2 protein binds to NR1I2 protein]"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate metabolite binds to and results in increased activity of NR1I2 protein"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate promotes the reaction [NCOA1 protein binds to NR1I2 protein]"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in decreased expression of NR1I2 mRNA"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"NR1I2 mRNA promotes the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in increased expression of CYP2B6 mRNA]"28289823
C000611514ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate"NR1I2 mRNA promotes the reaction [ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate results in increased expression of CYP3A4 mRNA]"28289823
C041062ethyl bromophosethyl bromophos binds to and results in increased activity of NR1I2 protein21115097
C041062ethyl bromophosethyl bromophos binds to and results in increased activity of NR1I2 protein21115097
C024565ethylene dichlorideethylene dichloride results in decreased expression of NR1I2 mRNA28189721
C045989eticloprideeticlopride results in increased activity of NR1I2 protein25455453
C045989eticlopride[eticlopride results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D012968Etidronic AcidEtidronic Acid results in increased activity of NR1I2 protein25455453
D005047EtoposideEtoposide results in increased activity of NR1I2 protein25455453
D005047Etoposide[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D005047EtoposideNR1I2 protein affects the susceptibility to Etoposide17279585
D015025ZearalenoneZearalenone results in increased activity of NR1I2 protein15569515
D015025ZearalenoneZearalenone results in decreased expression of NR1I2 mRNA20607812
D015736FelodipineFelodipine results in increased activity of NR1I2 protein27732639
D015736FelodipineFelodipine results in increased activity of NR1I2 protein27732883
D015736FelodipineFelodipine results in increased activity of NR1I2 protein27732639
C002698fenamiphosfenamiphos affects the activity of NR1I2 protein23611293
C002698fenamiphosfenamiphos binds to and results in increased activity of NR1I2 protein21115097
C002698fenamiphosfenamiphos binds to and results in increased activity of NR1I2 protein21115097
C033789fenarimolfenarimol binds to and results in increased activity of NR1I2 protein21115097
C033789fenarimolfenarimol results in increased activity of NR1I2 protein16565514
C033789fenarimolfenarimol binds to and results in increased activity of NR1I2 protein21115097
C504383fenbuconazolefenbuconazole results in increased activity of NR1I2 protein16565514
D005278Fenitrothion"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
D011345FenofibrateFenofibrate binds to and results in increased activity of NR1I2 protein20024649
C017690fenvaleratefenvalerate binds to and results in increased activity of NR1I2 protein16054614|2111509
C017690fenvaleratefenvalerate results in increased activity of NR1I2 protein15548381|1924932
C017690fenvaleratefenvalerate results in increased activity of NR1I2 protein polymorphism19249324
C017690fenvaleratefenvalerate affects the expression of NR1I2 mRNA20003521
C017690fenvaleratefenvalerate binds to and results in increased activity of NR1I2 protein21115097
C017690fenvaleratefenvalerate results in increased activity of NR1I2 protein19249324
C093230fexofenadine[fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D018120FinasterideFinasteride results in increased activity of NR1I2 protein21068194
C082360fipronilfipronil results in decreased expression of NR1I2 mRNA27091632
C082360fipronilfipronil results in increased activity of NR1I2 protein16565514|2014388
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of ABCC3 mRNA]23962444
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of CES2A mRNA]23962444
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of CYP3A11 mRNA]23962444
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of GSTA2 mRNA]23962444
C082360fipronilNR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of SLCO1A4 mRNA]23962444
D005411Flame RetardantsFlame Retardants results in increased activity of NR1I2 protein29112739
D015725FluconazoleFluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
C027975flucythrinateflucythrinate binds to and results in increased activity of NR1I2 protein21115097
C027975flucythrinateflucythrinate binds to and results in increased activity of NR1I2 protein21115097
C108339fludioxonil[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein25028461
C007734flunisolideflunisolide results in increased activity of NR1I2 protein21068194
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of NR1I2 mRNA16381673
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of NR1I2 mRNA16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A11 mRNA]16381673
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of NR1I2 mRNA16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP3A23/3A1 mRNA]12504080
D005485FlutamideFlutamide binds to and results in increased activity of NR1I2 protein18839173
D005485FlutamideFlutamide results in increased activity of NR1I2 protein20041327
D005485Flutamide[Flutamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
D005485FlutamideNR1I2 protein promotes the reaction [Flutamide results in increased expression of and results in increased activity of ABCB1 protein]20041327
D005485FlutamideFlutamide results in decreased expression of NR1I2 mRNA24793618
D000068298FluticasoneFluticasone results in increased activity of NR1I2 protein21068194
C475882flutolanilflutolanil binds to and results in increased activity of NR1I2 protein21115097
C475882flutolanilflutolanil binds to and results in increased activity of NR1I2 protein21115097
C034227fluvalinatefluvalinate binds to and results in increased activity of NR1I2 protein21115097
C034227fluvalinatefluvalinate binds to and results in increased activity of NR1I2 protein21115097
C065180fluvastatin[fluvastatin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA24204015
C065180fluvastatin[fluvastatin co-treated with NR1I2 protein] results in increased expression of G6PC mRNA24204015
C065180fluvastatin[fluvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA24204015
C065180fluvastatinfluvastatin results in increased activity of NR1I2 protein15802384
C094127FOE 5043FOE 5043 affects the activity of NR1I2 protein23611293
C094127FOE 5043FOE 5043 results in increased activity of NR1I2 protein20143881
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of NR1I2 mRNA20938992
D015378ImipenemImipenem results in increased activity of NR1I2 protein25455453
C070081fulvestrantfulvestrant results in increased activity of NR1I2 protein15885729
C037032galangingalangin binds to and results in increased activity of NR1I2 protein26238175
C037032galangingalangin promotes the reaction [NCOA1 protein binds to NR1I2 protein]26238175
C037032galangingalangin promotes the reaction [NCOA2 protein binds to NR1I2 protein]26238175
C037032galangingalangin promotes the reaction [NCOA3 protein binds to NR1I2 protein]26238175
C037032galangingalangin results in increased activity of NR1I2 protein26238175
D019833GenisteinGenistein binds to and results in increased activity of NR1I2 protein16054614
C048393germacronegermacrone results in increased activity of NR1I2 protein23850985
C048393germacronegermacrone results in increased activity of NR1I2 protein23850985
C477042ginkgolide Aginkgolide A results in increased activity of NR1I2 protein19034627
C045856ginkgolide Bginkgolide B affects the localization of NR1I2 protein26775663
C045856ginkgolide Bginkgolide B results in increased activity of NR1I2 protein19034627
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE mRNA]]26775663
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of SELE protein]]26775663
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]26775663
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]26775663
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]26775663
C045856ginkgolide BNR1I2 protein affects the reaction [ginkgolide B results in increased expression of CYP3A4 mRNA]26775663
C057619glimepirideglimepiride results in increased activity of NR1I2 protein25455453
C057619glimepiride[glimepiride results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D005938Glucocorticoids[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I224555085
D005938Glucocorticoids[[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I2] which results in increased expression of CYP3A424555085
D005938Glucocorticoids[[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I2] which results in increased expression of CYP3A524555085
D005938Glucocorticoids[[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I2] which results in increased expression of CYP3A724555085
D005947GlucoseGlucose results in decreased activity of NR1I2 protein21682256
D005947GlucoseGlucose results in decreased expression of NR1I2 mRNA22363694
D005947GlucoseKetoconazole inhibits the reaction [NR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose]26616219
D005947GlucoseNR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose26616219
D005947GlucosePolyphenols inhibits the reaction [Glucose results in decreased activity of NR1I2 protein]21682256
D005947Glucoseresveratrol inhibits the reaction [NR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose]26616219
D005947GlucoseSGK2 mutant form inhibits the reaction [[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose]24204015
D005947Glucose[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose24204015
D019695Glycyrrhizic AcidGlycyrrhizic Acid results in increased activity of NR1I2 protein22982774
D019695Glycyrrhizic AcidNR1I2 protein affects the reaction [Glycyrrhizic Acid results in increased expression of CYP3A4 mRNA]22982774
C018562guggulu extractguggulu extract results in increased activity of NR1I2 protein15075359
C018562guggulu extractguggulu extract results in increased activity of NR1I2 protein15075359
C412815GW 4064GW 4064 results in increased expression of NR1I2 mRNA26655953
D006533HeptachlorHeptachlor binds to and results in increased activity of NR1I2 protein21115097
D006533HeptachlorHeptachlor binds to and results in increased activity of NR1I2 protein21115097
D006534Heptachlor EpoxideHeptachlor Epoxide binds to and results in increased activity of NR1I2 protein21115097
D006534Heptachlor EpoxideHeptachlor Epoxide binds to and results in increased activity of NR1I2 protein21115097
C013015hesperetinhesperetin results in increased activity of NR1I2 protein25455453
C517828hexabrominated diphenyl ether 153"[2,2',4,4'-tetrabromodiphenyl ether co-treated with 2,2',4,4',5-brominated diphenyl ether co-treated with pentabrominated diphenyl ether 100 co-treated with hexabrominated diphenyl ether 153 co-treated with hexabromodiphenyl ether 154] results in increased activity of NR1I2 protein"25680588
C517828hexabrominated diphenyl ether 153hexabrominated diphenyl ether 153 results in increased activity of NR1I2 protein25680588
C089796hexabromocyclododecane[hexabromocyclododecane analog co-treated with hexabromocyclododecane analog co-treated with hexabromocyclododecane analog] results in increased activity of NR1I2 protein25680588
C089796hexabromocyclododecane[hexabromocyclododecane analog co-treated with hexabromocyclododecane analog co-treated with hexabromocyclododecane analog] results in increased activity of NR1I2 protein25680588
C533761hexabromodiphenyl ether 154"[2,2',4,4'-tetrabromodiphenyl ether co-treated with 2,2',4,4',5-brominated diphenyl ether co-treated with pentabrominated diphenyl ether 100 co-treated with hexabrominated diphenyl ether 153 co-treated with hexabromodiphenyl ether 154] results in increased activity of NR1I2 protein"25680588
D006589HexestrolHexestrol binds to and results in increased activity of NR1I2 protein20869355
D017313FenretinideFenretinide promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
C027492Huang QiHuang Qi results in increased activity of NR1I2 protein16267138
D006826HycanthoneHycanthone results in increased activity of NR1I2 protein25455453
C013024hydrastinehydrastine results in increased activity of NR1I2 protein25455453
D006859HydrogenHydrogen binds to NR1I2 protein15807509
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of NR1I2 mRNA26846883
C084794hydroxyitraconazolehydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
C084794hydroxyitraconazolehydroxyitraconazole results in decreased activity of NR1I2 protein17438109
C001654hyperforinhyperforin binds to and results in increased activity of NR1I2 protein15630458
C001654hyperforinhyperforin binds to NR1I2 protein27071811
C001654hyperforinhyperforin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]26920453
C001654hyperforinhyperforin results in increased activity of NR1I2 protein15856409|2618727
C001654hyperforinNR1I2 protein affects the reaction [hyperforin results in increased expression of CYP2C9 mRNA]14600250
C001654hyperforin[NR1I2 protein co-treated with hyperforin] results in decreased expression of SLC22A1 mRNA26920453
C001654hyperforinNR1I2 protein promotes the reaction [hyperforin results in increased abundance of Lipids]20079722
C001654hyperforinNR1I2 protein results in increased susceptibility to hyperforin26920453
C001654hyperforin[NR1I2 protein results in increased susceptibility to hyperforin] which results in decreased expression of SLC22A1 mRNA26920453
D007069IfosfamideIfosfamide binds to and results in increased activity of NR1I2 protein18839173
D007069IfosfamideIfosfamide results in increased activity of NR1I2 protein20041327
D007069Ifosfamide[Ifosfamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
D007069IfosfamideNR1I2 protein promotes the reaction [Ifosfamide results in increased expression of ABCB1 protein]20041327
C494197imazamoximazamox affects the activity of NR1I2 protein23611293
C464480indanofanindanofan binds to and results in increased activity of NR1I2 protein21115097
C464480indanofanindanofan binds to and results in increased activity of NR1I2 protein21115097
D007216IndoprofenIndoprofen results in increased activity of NR1I2 protein25455453
D007065IdoxuridineIdoxuridine results in increased activity of NR1I2 protein25455453
C033148iprodione[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein25028461
D007528IsoetharineIsoetharine results in increased activity of NR1I2 protein25455453
C035019isofenphosisofenphos binds to and results in increased activity of NR1I2 protein21115097
C035019isofenphosisofenphos metabolite binds to and results in increased activity of NR1I2 protein21115097
C035019isofenphosisofenphos binds to and results in increased activity of NR1I2 protein21115097
C035019isofenphosisofenphos metabolite binds to and results in increased activity of NR1I2 protein21115097
C015304isopimpinellinisopimpinellin results in increased activity of NR1I2 protein18692084
C015304isopimpinellinisopimpinellin results in increased activity of NR1I2 protein18692084
C015304isopimpinellinisopimpinellin promotes the reaction [NR1I2 protein binds to NCOA1 protein]18692084
C038267isopropyl 4,4'-dibromobenzilate"isopropyl 4,4'-dibromobenzilate binds to and results in increased activity of NR1I2 protein"21115097
C038267isopropyl 4,4'-dibromobenzilate"isopropyl 4,4'-dibromobenzilate binds to and results in increased activity of NR1I2 protein"21115097
C023889isoprothiolaneisoprothiolane binds to and results in increased activity of NR1I2 protein21115097
C023889isoprothiolaneisoprothiolane binds to and results in increased activity of NR1I2 protein21115097
C028904isoproturonisoproturon results in increased activity of NR1I2 protein16565514
C028904isoproturonisoproturon results in increased expression of NR1I2 mRNA22310298
C057467isoxabenisoxaben results in increased activity of NR1I2 protein20143881
D007555IsoxazolesIsoxazoles results in increased activity of NR1I2 protein26187274
D017275IsradipineIsradipine results in increased activity of NR1I2 protein27732883
D017964ItraconazoleItraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
D017964ItraconazoleItraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]17998298
D017964ItraconazoleItraconazole results in increased expression of NR1I2 mRNA17998298
D017964ItraconazoleItraconazole inhibits the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]19954708
D017964ItraconazoleItraconazole results in increased activity of NR1I2 protein28390928
D017964ItraconazoleItraconazole results in increased expression of NR1I2 mRNA28390928
C006552kaempferolkaempferol results in increased activity of NR1I2 protein19034627|2545545
C006552kaempferol[kaempferol results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
C006552kaempferolkaempferol results in increased activity of NR1I2 protein26238175
D007654KetoconazoleKetoconazole binds to and results in decreased activity of NR1I2 protein17998298|2352510
D007654Ketoconazole[Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D007654KetoconazoleKetoconazole inhibits the reaction [Corticosterone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]12072427
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein binds to NCOA1 protein]12072427|1799829
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein binds to NCOR2 protein]12072427
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [NR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose]26616219
D007654KetoconazoleKetoconazole inhibits the reaction [Paclitaxel promotes the reaction [NR1I2 protein binds to NCOA1 protein]]16819505
D007654KetoconazoleKetoconazole inhibits the reaction [Paclitaxel results in increased activity of NR1I2 protein]16819505
D007654KetoconazoleKetoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]23707768
D007654KetoconazoleKetoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]17998298
D007654KetoconazoleKetoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]16819505|1743810
D007654KetoconazoleKetoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]21402137
D007654KetoconazoleKetoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]16608920|1681950
D007654KetoconazoleKetoconazole results in decreased expression of NR1I2 mRNA16608920|1799829
D007654KetoconazoleKetoconazole results in decreased expression of NR1I2 protein16608920
D007654KetoconazoleKetoconazole results in increased activity of NR1I2 protein25343516|2568058
D007654KetoconazoleNR1I2 protein mutant form results in decreased susceptibility to Ketoconazole17438109
D007654KetoconazoleKetoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]16819505
D007654KetoconazoleKetoconazole analog results in decreased activity of NR1I2 protein18583127
D007654KetoconazoleKetoconazole analog results in increased activity of NR1I2 protein18583127
D007654Ketoconazole[Ketoconazole binds to and results in decreased activity of NR3C1 protein] which results in decreased expression of NR1I221333771
D007654KetoconazoleKetoconazole inhibits the reaction [[NR1I2 binds to HNF4A] which results in increased expression of CYP3A4]19077665
D007654KetoconazoleKetoconazole results in decreased activity of NR1I2 protein18583127
D007654KetoconazoleKetoconazole results in increased activity of NR1I2 protein18583127
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I2 mRNA18544905
C099406L 742694L 742694 binds to and results in increased activity of NR1I2 protein15102944
C099406L 742694L 742694 results in increased expression of NR1I2 mRNA15102944
D064747LansoprazoleLansoprazole results in increased activity of NR1I2 protein25455453
C045463leflunomideleflunomide results in increased activity of NR1I2 protein25455453
C045463leflunomide[leflunomide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D010773LeptophosLeptophos binds to and results in increased activity of NR1I2 protein21115097
D010773LeptophosLeptophos binds to and results in increased activity of NR1I2 protein21115097
D008012LidocaineLidocaine results in increased activity of NR1I2 protein25455453
D017705LignansLignans metabolite results in increased activity of NR1I2 protein15885729
C027820ligustilideligustilide results in increased activity of NR1I2 protein21524698
C027820ligustilide[ligustilide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA21524698
D001556LindaneLindane binds to and results in increased activity of NR1I2 protein16054614
D001556LindaneLindane results in increased activity of NR1I2 protein15548381|2568058
D001556LindaneLindane binds to and results in increased activity of NR1I2 protein14613717
D001556LindaneLindane results in increased expression of NR1I2 mRNA25572523
D001556LindaneLindane binds to and results in increased activity of NR1I2 protein16054614
D001556LindaneLindane results in increased activity of NR1I2 protein25680588
D008044Linuron[Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein25028461
D008044LinuronLinuron binds to and results in increased activity of NR1I2 protein21115097
D008044LinuronLinuron binds to and results in increased activity of NR1I2 protein21115097
D008044Linuron[Diethylhexyl Phthalate co-treated with Linuron] results in increased expression of NR1I2 mRNA22277248
D008055LipidsNR1I2 protein affects the abundance of Lipids20079722
D008055LipidsNR1I2 protein promotes the reaction [hyperforin results in increased abundance of Lipids]20079722
D008055LipidsNR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]20079722
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of NR1I2 mRNA15312234|1561753
D008070LipopolysaccharidesMelatonin inhibits the reaction [Lipopolysaccharides results in decreased expression of NR1I2 mRNA]15617534
D008070Lipopolysaccharidesphenyl-N-tert-butylnitrone inhibits the reaction [Lipopolysaccharides results in decreased expression of NR1I2 mRNA]15976188
D008095Lithocholic AcidLithocholic Acid analog binds to and results in increased activity of NR1I2 protein17963371
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of NR1I2 protein15883047|1605461
D008095Lithocholic AcidLithocholic Acid results in increased activity of NR1I2 protein22561792|2787190
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA14570758
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A11 mRNA14570758
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA22561792
D008095Lithocholic AcidLithocholic Acid results in increased localization of NR1I2 protein21977915
D008095Lithocholic AcidNR1I2 protein promotes the reaction [Lithocholic Acid results in increased expression of FGF19 mRNA]17696253
D008095Lithocholic AcidNR1I2 protein results in decreased susceptibility to Lithocholic Acid12370413
D008095Lithocholic AcidNR1I2 protein results in decreased susceptibility to Lithocholic Acid15358766
D008095Lithocholic AcidNR1I2 results in increased susceptibility to Lithocholic Acid19797606
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of NR1I2 protein21311750
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA21311750
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A23/3A1 mRNA21311750
D008095Lithocholic AcidLithocholic Acid results in decreased expression of NR1I2 mRNA20888898|2131175
D008095Lithocholic AcidLithocholic Acid results in decreased expression of NR1I2 protein21311750
D008095Lithocholic Acid[NR1I2 protein co-treated with RXRA protein] promotes the reaction [Lithocholic Acid results in increased expression of SULT2A1 mRNA]12370413
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of NR1I2 protein16054614
D008095Lithocholic AcidLithocholic Acid binds to and results in increased activity of NR1I2 protein21291553
C502354lithocholic acid acetatelithocholic acid acetate binds to and results in increased activity of NR1I2 protein21291553
D008139Loperamide[Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D008148Lovastatin[Lovastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D008300Maleic Hydrazide[Maleic Hydrazide co-treated with Chlorpropham] results in increased activity of NR1I2 protein25028461
C054137mecarbammecarbam binds to and results in increased activity of NR1I2 protein21115097
C054137mecarbammecarbam binds to and results in increased activity of NR1I2 protein21115097
D008472MedazepamMedazepam binds to and results in increased activity of NR1I2 protein20024649
D008472MedazepamMedazepam results in increased activity of NR1I2 protein20080160
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in increased activity of NR1I2 protein15650019
C425686mefenacetmefenacet binds to and results in increased activity of NR1I2 protein21115097
C425686mefenacetmefenacet binds to and results in increased activity of NR1I2 protein21115097
D008535MegestrolMegestrol results in increased activity of NR1I2 protein21068194
D008550MelatoninMelatonin inhibits the reaction [Lipopolysaccharides results in decreased expression of NR1I2 mRNA]15617534
D008610MentholMenthol affects the localization of NR1I2 protein24594507
D008617MephenytoinMephenytoin binds to and results in increased activity of NR1I2 protein15039302
D008618MephobarbitalMephobarbital binds to and results in increased activity of NR1I2 protein15039302
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of NR1I2 mRNA16507785
D008687MetforminNR1I2 protein affects the susceptibility to [Pregnenolone Carbonitrile co-treated with Metformin]21920351
D008687MetforminMetformin results in decreased expression of NR1I2 mRNA19022234
D008687MetforminMetformin inhibits the reaction [NR1I2 protein binds to NCOA1 protein]21920351
D016210Methacholine ChlorideNR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with Methacholine Chloride]17159084
D008701MethapyrileneMethapyrilene results in decreased expression of NR1I2 mRNA17450226
C005828methidathion[enilconazole co-treated with methidathion] results in increased activity of NR1I2 protein25028461
D008714MethiocarbMethiocarb results in increased activity of NR1I2 protein27665777
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of NR1I2 mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NR1I2 mRNA18488193
D008727MethotrexateMethotrexate results in decreased expression of NR1I2 mRNA16925582
D008731MethoxychlorMethoxychlor binds to and results in increased activity of NR1I2 protein16054614|2111509
D008731MethoxychlorMethoxychlor results in increased activity of NR1I2 protein15548381|2568058
D008731MethoxychlorMethoxychlor binds to and results in increased activity of NR1I2 protein21115097
D008731MethoxychlorMethoxychlor binds to and results in increased activity of NR1I2 protein14613717
D008731MethoxychlorMethoxychlor binds to and results in increased activity of NR1I2 protein16054614
D008731MethoxychlorMethoxychlor results in increased activity of NR1I2 protein25680588
D008730MethoxsalenMethoxsalen results in increased activity of NR1I2 protein17003103|2545545
D008730MethoxsalenNR1I2 protein promotes the reaction [Methoxsalen results in increased expression of CES2 mRNA]17003103
D008730MethoxsalenNR1I2 protein promotes the reaction [Methoxsalen results in increased expression of CYP3A4 mRNA]17003103
D008730MethoxsalenMethoxsalen results in increased activity of NR1I2 protein17003103
C071475methyl bensulfuronmethyl bensulfuron results in increased activity of NR1I2 protein22206814
D008748MethylcholanthreneMethylcholanthrene binds to NR1I2 protein24663500
D012862SkatoleSkatole results in decreased expression of NR1I2 mRNA28571685
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Amphetamine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Diazepam promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]"21402137
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforafan results in decreased expression of NR1I2 mRNA]"21871945
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NR1I2 mRNA"21402137|2187194
D018817N-Methyl-3,4-methylenedioxyamphetamine"sulforafan inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NR1I2 mRNA]"21871945
C051786metolachlormetolachlor binds to and results in increased activity of NR1I2 protein21115097
C051786metolachlormetolachlor results in increased activity of NR1I2 protein16565514
C051786metolachlormetolachlor binds to and results in increased activity of NR1I2 protein21115097
D008788MetolazoneMetolazone results in increased activity of NR1I2 protein25455453
D008788Metolazone[Metolazone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D008797MetyraponeMetyrapone results in increased activity of NR1I2 protein16919048
D008797Metyrapone[Metyrapone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D008797Metyrapone[Metyrapone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D008797MetyraponeMetyrapone results in increased activity of NR1I2 protein16919048
C012258mevastatin[mevastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
C012258mevastatinNR1I2 protein promotes the reaction [mevastatin results in increased expression of CYP3A4 mRNA]12235278
D008825MiconazoleMiconazole results in increased activity of NR1I2 protein28259787
D008825MiconazoleMiconazole binds to and results in increased activity of NR1I2 protein17998298
D008825MiconazoleMiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D008825MiconazoleMiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]17998298
D008825MiconazoleMiconazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
D008825MiconazoleMiconazole results in decreased activity of NR1I2 protein17438109
D008825MiconazoleMiconazole results in decreased expression of NR1I2 mRNA16608920|1799829
D008825MiconazoleMiconazole results in increased activity of NR1I2 protein28259787
D008825MiconazoleMiconazole results in increased activity of NR1I2 protein27732639
D008825Miconazole[Miconazole binds to and results in decreased activity of NR3C1 protein] which results in decreased expression of NR1I221333771
D008874MidazolamMidazolam results in increased activity of NR1I2 protein20080160
D008874MidazolamNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]18799805
D015735MifepristoneMifepristone binds to and results in increased activity of NR1I2 protein16054614
D015735MifepristoneMifepristone results in increased activity of NR1I2 protein26187274
D015735Mifepristone[Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D015735Mifepristone[Mifepristone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D015735MifepristoneNR1I2 protein promotes the reaction [Mifepristone results in increased expression of CYP3A4 mRNA]12235278
D015735MifepristoneMifepristone results in increased activity of NR1I2 protein15456840
D015735MifepristoneMifepristone results in increased expression of NR1I2 mRNA14570758
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]20599767
D015735MifepristoneMifepristone binds to and results in increased activity of NR1I2 protein16054614
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[Diethylhexyl Phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I2 protein16054614
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased activity of NR1I2 protein27551952
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I2 protein16054614
C016599mono-(2-ethylhexyl)phthalateDexamethasone promotes the reaction [[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]18332045
C016599mono-(2-ethylhexyl)phthalateMifepristone inhibits the reaction [Dexamethasone promotes the reaction [[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]]18332045
C016599mono-(2-ethylhexyl)phthalate[mono-(2-ethylhexyl)phthalate co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA18332045
C006429monobenzonemonobenzone results in increased activity of NR1I2 protein25455453
C006429monobenzone[monobenzone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
C103325mono-benzyl phthalatemono-benzyl phthalate results in increased activity of NR1I2 protein27551952
C028577monobutyl phthalatemonobutyl phthalate results in increased activity of NR1I2 protein15901914
D008999MonocrotophosMonocrotophos affects the expression of NR1I2 protein22733800
D008999MonocrotophosMonocrotophos binds to NR1I2 protein24663500
D008999Monocrotophos[Monocrotophos co-treated with Cimetidine] results in increased expression of NR1I2 protein22733800
D008999Monocrotophos[Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein22733800
C471400monoisononylphthalatemonoisononylphthalate results in increased activity of NR1I2 protein27551952
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of NR1I2 mRNA19084030
C517284monomethyl phthalatemonomethyl phthalate results in decreased expression of NR1I2 mRNA26924002
C420606mulberroside Amulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]27918128
C420606mulberroside Amulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]27918128
D009173Mycophenolic AcidMycophenolic Acid results in increased activity of NR1I2 protein25455453
D009173Mycophenolic Acid[Mycophenolic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased activity of NR1I2 protein"29244179
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased activity of NR1I2 protein"29244179
C572868N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide"NR1I2 protein affects the reaction [N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide results in increased activity of CYP3A11 protein]"25455223
C572868N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide"NR1I2 protein affects the reaction [N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide results in increased expression of TSHB mRNA]"25455223
C572868N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide"NR1I2 protein results in increased susceptibility to N-(2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)ethyl)-alpha,alpha,alpha-trifluoro-o-toluamide"25455223
C451426N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
C035605nabumetonenabumetone results in increased activity of NR1I2 protein25455453
D009254NafcillinNafcillin results in increased activity of NR1I2 protein25455453
D009257NafronylNafronyl results in increased activity of NR1I2 protein25455453
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of NR1I2 mRNA"25620056
C002684naphtholphthaleinnaphtholphthalein binds to and results in increased activity of NR1I2 protein20869355
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of NR1I2 mRNA15913567
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of NR1I2 mRNA27765674
C005273naringeninnaringenin results in increased activity of NR1I2 protein25455453
C070021N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide"[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein"25028461
D019888NelfinavirNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]18799805
D009529NicardipineNicardipine results in increased activity of NR1I2 protein25455453
D009529Nicardipine[Nicardipine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D009543NifedipineNifedipine binds to and results in increased activity of NR1I2 protein21291553
D009543Nifedipineallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]25069801
D009543NifedipineNifedipine binds to and results in increased activity of NR1I2 protein21291553
D009543Nifedipine[Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D009543Nifedipine[Nifedipine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D009543NifedipineNR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]25069801
D009553NimodipineNimodipine results in increased activity of NR1I2 protein21068194|2545545
C007350nitrofennitrofen binds to and results in increased activity of NR1I2 protein21115097
C007350nitrofennitrofen binds to and results in increased activity of NR1I2 protein21115097
C121756N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamideNR1I2 protein affects the susceptibility to [5-alpha-Dihydroprogesterone co-treated with N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide]17159084
C001870nonachlornonachlor binds to and results in increased activity of NR1I2 protein16054614
C001870nonachlornonachlor results in increased activity of NR1I2 protein15548381|1588572
C001870nonachlornonachlor binds to and results in increased activity of NR1I2 protein16054614
C025256nonylphenolnonylphenol binds to and results in increased activity of NR1I2 protein16054614
C025256nonylphenolNR1I2 protein affects the susceptibility to nonylphenol21376070
C025256nonylphenolNR1I2 protein results in increased susceptibility to nonylphenol21376070
C025256nonylphenolnonylphenol binds to and results in increased activity of NR1I2 protein14613717
C025256nonylphenolnonylphenol binds to and results in increased activity of NR1I2 protein16054614
C025256nonylphenol[nonylphenol co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA10707959
C025256nonylphenolnonylphenol promotes the reaction [NCOA1 protein binds to NR1I2 protein]10707959
C025256nonylphenolnonylphenol promotes the reaction [NRIP1 protein binds to NR1I2 protein]10707959
C072936notoginsenoside R1notoginsenoside R1 binds to and results in increased activity of NR1I2 protein25472953
C072936notoginsenoside R1NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of ABCB1 mRNA]25472953
C072936notoginsenoside R1NR1I2 protein promotes the reaction [notoginsenoside R1 results in increased expression of UGT1A1 mRNA]25472953
C072936notoginsenoside R1NR1I2 protein results in increased susceptibility to notoginsenoside R125472953
C072936notoginsenoside R1notoginsenoside R1 results in increased activity of NR1I2 protein25472953
C025589ochratoxin ADactinomycin inhibits the reaction [ochratoxin A results in decreased expression of NR1I2 mRNA]26341324
C025589ochratoxin Aochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]26341324
C025589ochratoxin Aochratoxin A results in decreased expression of NR1I2 mRNA26341324
C025589ochratoxin Aochratoxin A results in decreased expression of NR1I2 protein26341324
C024064octamethylcyclotetrasiloxaneoctamethylcyclotetrasiloxane results in increased activity of NR1I2 protein25680588
D019319Okadaic AcidOkadaic Acid results in decreased activity of NR1I2 protein15710363
D019319Okadaic AcidOkadaic Acid results in increased activity of NR1I2 protein22206814|2692172
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of NR1I2 mRNA"23333450
D015525Fatty Acids, Omega-3"NR1H2 gene mutant form inhibits the reaction [Fatty Acids, Omega-3 results in decreased expression of NR1I2 mRNA]"23333450
D015525Fatty Acids, Omega-3"NR1H3 gene mutant form inhibits the reaction [Fatty Acids, Omega-3 results in decreased expression of NR1I2 mRNA]"23333450
D009853OmeprazoleOmeprazole results in increased activity of NR1I2 protein27732639
D009853OmeprazoleNR1I2 protein affects the reaction [Omeprazole results in increased expression of CYP3A4 mRNA]12695340
D009853OmeprazoleOmeprazole results in increased activity of NR1I2 protein25680588|2618727
D009853Omeprazole[Omeprazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D009853OmeprazoleOmeprazole results in increased activity of NR1I2 protein27732639
C002771Omite"[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein"25028461
C009897O,O-diisopropyl-S-benzylthiophosphate"O,O-diisopropyl-S-benzylthiophosphate binds to and results in increased activity of NR1I2 protein"21115097
C009897O,O-diisopropyl-S-benzylthiophosphate"O,O-diisopropyl-S-benzylthiophosphate binds to and results in increased activity of NR1I2 protein"21115097
C016340o,p'-DDT"o,p'-DDT binds to and results in increased activity of NR1I2 protein"16054614|2111509
C016340o,p'-DDT"o,p'-DDT results in increased activity of NR1I2 protein"15548381
C016340o,p'-DDT"o,p'-DDT affects the expression of NR1I2 mRNA"18925944
C016340o,p'-DDT"o,p'-DDT binds to and results in increased activity of NR1I2 protein"21115097
C016340o,p'-DDT"o,p'-DDT affects the expression of NR1I2 mRNA"17984292
C055122orlistatorlistat results in increased activity of NR1I2 protein20599501
D008939MitotaneMitotane promotes the reaction [NCOA1 protein binds to NR1I2 protein]23179081
D008939MitotaneMitotane promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]23179081
D008939MitotaneNR1I2 protein promotes the reaction [Mitotane results in increased expression of CYP3A4 mRNA]23179081
D008939MitotaneMitotane results in increased activity of NR1I2 protein25542188
C012466oxadiazonoxadiazon results in increased activity of NR1I2 protein16565514
C022155oxiconazoleNR1I2 promotes the reaction [oxiconazole results in increased expression of CYP3A4 protein]17998298
C022155oxiconazoleNR1I2 results in increased susceptibility to oxiconazole17998298
C022155oxiconazoleoxiconazole binds to and results in increased activity of NR1I2 protein17998298
C022155oxiconazoleoxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]17998298
C022155oxiconazoleoxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
C022155oxiconazoleoxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]17998298
C022155oxiconazoleoxiconazole promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
C022155oxiconazoleoxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
C022155oxiconazoleoxiconazole results in decreased activity of NR1I2 protein17438109
C022155oxiconazoleoxiconazole results in decreased expression of NR1I2 mRNA17998298
C022155oxiconazoleRifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
C022155oxiconazoleRifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]17998298
D010098OxycodoneOxycodone results in increased expression of NR1I2 mRNA23439660
C016027oxyfluorofenoxyfluorofen binds to and results in increased activity of NR1I2 protein21115097
C016027oxyfluorofenoxyfluorofen binds to and results in increased activity of NR1I2 protein21115097
D010100OxygenOxygen deficiency results in decreased expression of NR1I2 mRNA19695866
D017239PaclitaxelKetoconazole inhibits the reaction [Paclitaxel promotes the reaction [NR1I2 protein binds to NCOA1 protein]]16819505
D017239PaclitaxelKetoconazole inhibits the reaction [Paclitaxel results in increased activity of NR1I2 protein]16819505
D017239PaclitaxelNR1I2 protein promotes the reaction [Paclitaxel results in increased expression of and results in increased activity of ABCB1 protein]20041327
D017239PaclitaxelPaclitaxel binds to and results in increased activity of NR1I2 protein14977870|1586413
D017239PaclitaxelPaclitaxel promotes the reaction [NR1I2 protein binds to MED1 protein]15650019
D017239PaclitaxelPaclitaxel promotes the reaction [NR1I2 protein binds to NCOA1 protein]16819505
D017239PaclitaxelPaclitaxel promotes the reaction [NR1I2 protein binds to NCOA3 protein]15650019
D017239PaclitaxelPaclitaxel results in increased activity of NR1I2 protein12065438|1565001
D017239Paclitaxel[Paclitaxel results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
D017239Paclitaxel[SR 12813 results in increased activity of NR1I2 protein] which results in decreased susceptibility to Paclitaxel19746521
D017239PaclitaxelNR1I2 gene mutant form results in increased abundance of Paclitaxel17438109
C016030pantogabpantogab results in increased expression of NR1I2 mRNA17379144
D010269Paraquat[NR1I2 protein results in decreased activity of CAT protein] which results in increased susceptibility to Paraquat16195250
D010269ParaquatNR1I2 protein results in increased susceptibility to Paraquat16195250
D010269ParaquatParaquat results in decreased expression of NR1I2 protein26196221
D010269ParaquatNR1I2 gene mutant form results in increased susceptibility to Paraquat16195250
D010278ParathionParathion binds to and results in increased activity of NR1I2 protein21115097
D010278ParathionParathion results in increased activity of NR1I2 protein26196221
D010278ParathionParathion binds to and results in increased activity of NR1I2 protein21115097
C002669parthenolideparthenolide results in increased activity of NR1I2 protein25455453
D052638Particulate MatterParticulate Matter analog results in decreased expression of NR1I2 mRNA20026096
C410127PCB 180PCB 180 binds to and results in increased activity of NR1I2 protein20024649
C410127PCB 180PCB 180 results in increased expression of NR1I2 mRNA22664347
C410127PCB 180NR1I2 gene mutant form inhibits the reaction [PCB 180 results in increased expression of CYP2B1 protein]23770461
C410127PCB 180NR1I2 gene mutant form promotes the reaction [PCB 180 results in increased expression of CYP2B1 mRNA]23770461
C410127PCB 180PCB 180 results in increased expression of NR1I2 mRNA23770461
C087058penconazole"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
C036791pencycuronpencycuron binds to and results in increased activity of NR1I2 protein21115097
C030856pendimethalinpendimethalin binds to and results in increased activity of NR1I2 protein21115097
C030856pendimethalinpendimethalin binds to and results in increased activity of NR1I2 protein21115097
C517827pentabrominated diphenyl ether 100"[2,2',4,4'-tetrabromodiphenyl ether co-treated with 2,2',4,4',5-brominated diphenyl ether co-treated with pentabrominated diphenyl ether 100 co-treated with hexabrominated diphenyl ether 153 co-treated with hexabromodiphenyl ether 154] results in increased activity of NR1I2 protein"25680588
C517827pentabrominated diphenyl ether 100pentabrominated diphenyl ether 100 results in increased activity of NR1I2 protein25680588
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased activity of NR1I2 protein17324954
C086401pentabromodiphenyl etherNR1I2 protein promotes the reaction [pentabromodiphenyl ether results in increased expression of CYP2B10 mRNA]17324954
C086401pentabromodiphenyl etherNR1I2 protein promotes the reaction [pentabromodiphenyl ether results in increased expression of CYP3A11 mRNA]17324954
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased activity of NR1I2 protein17324954
D010416PentachlorophenolPentachlorophenol results in increased expression of NR1I2 mRNA23892564
D010424PentobarbitalPentobarbital binds to and results in increased activity of NR1I2 protein15039302
C033094perfluorobutyric acidperfluorobutyric acid results in increased activity of NR1I2 protein28115241
C036567perfluorodecanoic acidperfluorodecanoic acid results in increased activity of NR1I2 protein28115241
C036567perfluorodecanoic acidDactinomycin inhibits the reaction [perfluorodecanoic acid results in increased expression of NR1I2 protein]15826607
C036567perfluorodecanoic acidperfluorodecanoic acid results in increased expression of NR1I2 protein15826607
C522391perfluorododecanoic acidperfluorododecanoic acid results in increased activity of NR1I2 protein28115241
C000610525perfluoroheptanoic acidperfluoroheptanoic acid results in increased activity of NR1I2 protein28115241
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of NR1I2 mRNA21705711
C479228perfluorohexanoic acidperfluorohexanoic acid results in increased activity of NR1I2 protein28115241
C584865perfluorononanoic acid[perfluorononanoic acid co-treated with perfluorooctanoic acid] results in increased activity of NR1I2 protein28115241
C584865perfluorononanoic acidperfluorononanoic acid results in increased activity of NR1I2 protein28115241
C584865perfluorononanoic acid[perfluorooctane sulfonic acid co-treated with perfluorononanoic acid] results in increased activity of NR1I2 protein28115241
C076994perfluorooctane sulfonic acid[perfluorooctane sulfonic acid co-treated with perfluorononanoic acid] results in increased activity of NR1I2 protein28115241
C076994perfluorooctane sulfonic acid[perfluorooctane sulfonic acid co-treated with perfluorooctanoic acid] results in increased activity of NR1I2 protein28115241
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased activity of NR1I2 protein28115241
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of NR1I2 mRNA21705711
C023036perfluorooctanoic acid[perfluorononanoic acid co-treated with perfluorooctanoic acid] results in increased activity of NR1I2 protein28115241
C023036perfluorooctanoic acid[perfluorooctane sulfonic acid co-treated with perfluorooctanoic acid] results in increased activity of NR1I2 protein28115241
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of NR1I2 mRNA25868421
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased activity of NR1I2 protein28115241
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of NR1I2 mRNA18281256
C023036perfluorooctanoic acidPPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of NR1I2 mRNA]18281256
D026023PermethrinPermethrin binds to and results in increased activity of NR1I2 protein21115097
D026023PermethrinPermethrin results in increased activity of NR1I2 protein16565514|1924932
D026023PermethrinPermethrin binds to and results in increased activity of NR1I2 protein21115097
D026023PermethrinPermethrin results in increased activity of NR1I2 protein19249324
D010634PhenobarbitalDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]]]12695351
D010634PhenobarbitalNR1I2 protein affects the reaction [Phenobarbital results in increased expression of and results in increased activity of CYP2B6 protein]12695351
D010634PhenobarbitalNR1I2 protein affects the reaction [Phenobarbital results in increased expression of CYP3A4 mRNA]12695340
D010634Phenobarbital[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [Phenobarbital results in increased expression of AHR mRNA]28058446
D010634PhenobarbitalNR1I2 protein promotes the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA]12695351
D010634PhenobarbitalPhenobarbital affects the expression of NR1I2 mRNA19084549
D010634PhenobarbitalPhenobarbital binds to and results in increased activity of NR1I2 protein14977870|1503930
D010634PhenobarbitalPhenobarbital results in increased activity of NR1I2 protein12065438|1554838
D010634PhenobarbitalNR1I2 affects the susceptibility to Phenobarbital20403969
D010634PhenobarbitalNR1I2 protein affects the reaction [Phenobarbital results in increased expression of MEG3 mRNA]23091169
D010634PhenobarbitalNR1I2 protein affects the reaction [Phenobarbital results in increased expression of RIAN mRNA]23091169
D010634PhenobarbitalPhenobarbital results in increased expression of NR1I2 mRNA19270015|2716021
D010634PhenobarbitalNR1I2 gene mutant form inhibits the reaction [Phenobarbital results in increased expression of CYP2B1 protein]23770461
D010634PhenobarbitalNR1I2 gene mutant form promotes the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA]23770461
D010634PhenobarbitalNR1I2 gene mutant form promotes the reaction [Phenobarbital results in increased expression of CYP3A23/3A1 mRNA]23770461
D010634PhenobarbitalPhenobarbital results in decreased expression of NR1I2 mRNA20607812
D010634PhenobarbitalPhenobarbital results in increased expression of NR1I2 mRNA23770461
D010634PhenobarbitalPhenobarbital results in increased expression of NR1I2 protein18473823
D010634PhenobarbitalNR1I2 protein binds to Phenobarbital22429928
D010634PhenobarbitalPhenobarbital results in increased activity of NR1I2 protein16857725|2309116
D020113PhenolphthaleinPhenolphthalein binds to and results in increased activity of NR1I2 protein20869355
C008838phenthoatephenthoate binds to and results in increased activity of NR1I2 protein21115097
C008838phenthoatephenthoate binds to and results in increased activity of NR1I2 protein21115097
D010656PhenylephrineNR1I2 protein affects the susceptibility to Phenylephrine17159084
C029217phenyl-N-tert-butylnitronephenyl-N-tert-butylnitrone inhibits the reaction [Lipopolysaccharides results in decreased expression of NR1I2 mRNA]15976188
D004849Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester"Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester binds to and results in increased activity of NR1I2 protein"21115097
D004849Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester"Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester binds to and results in increased activity of NR1I2 protein"21115097
D010672PhenytoinDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]]]12695351
D010672Phenytoin"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D010672PhenytoinNR1I2 protein affects the reaction [Phenytoin results in increased expression of and results in increased activity of CYP2B6 protein]12695351
D010672PhenytoinNR1I2 protein affects the reaction [Phenytoin results in increased expression of CYP2C9 mRNA]14600250
D010672PhenytoinNR1I2 protein affects the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]12695340
D010672PhenytoinNR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]12695351
D010672PhenytoinPhenytoin affects the activity of NR1I2 protein23611293
D010672PhenytoinPhenytoin binds to and results in increased activity of NR1I2 protein14977870|1503930
D010672PhenytoinPhenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
D010672PhenytoinPhenytoin results in increased activity of NR1I2 protein12065438
D010672PhenytoinPhenytoin results in increased expression of NR1I2 protein18473823
C119222phorbol-12-myristatephorbol-12-myristate promotes the reaction [NR1I2 protein binds to NCOR1 protein]15710363
C119222phorbol-12-myristatephorbol-12-myristate results in decreased activity of NR1I2 protein15710363
C003117phosalone"[Omite co-treated with Diphenylamine co-treated with phosalone co-treated with Captan co-treated with N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide] results in increased activity of NR1I2 protein"25028461
C003117phosalonephosalone binds to and results in increased activity of NR1I2 protein21115097
C003117phosalonephosalone binds to and results in increased activity of NR1I2 protein21115097
D010710PhosphatesNR1I2 protein mutant form results in decreased abundance of Phosphates19898264
C032279phthalic acidphthalic acid promotes the reaction [NR1I2 protein binds to MED1 protein]15650019
C032279phthalic acidphthalic acid promotes the reaction [NR1I2 protein binds to NCOA1 protein]15650019
C032279phthalic acidphthalic acid results in increased activity of NR1I2 protein15650019|2755195
C032279phthalic acid[phthalic acid co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA10707959
C032279phthalic acidphthalic acid promotes the reaction [NCOA1 protein binds to NR1I2 protein]10707959
C032279phthalic acidphthalic acid promotes the reaction [NRIP1 protein binds to NR1I2 protein]10707959
C008922piperineKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]]23707768
C008922piperineKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]]23707768
C008922piperineKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]]23707768
C008922piperineKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]]23707768
C008922piperineKetoconazole inhibits the reaction [piperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]]23707768
C008922piperineNR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 mRNA]23707768
C008922piperineNR1I2 protein promotes the reaction [piperine results in increased expression of ABCB1 protein]23707768
C008922piperineNR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 mRNA]23707768
C008922piperineNR1I2 protein promotes the reaction [piperine results in increased expression of CYP3A4 protein]23707768
C008922piperinepiperine binds to NR1I2 protein23707768
C008922piperine[piperine co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA23707768
C008922piperinepiperine promotes the reaction [NCOA1 protein binds to NR1I2 protein]23707768
C008922piperinepiperine results in increased activity of NR1I2 protein25455453
C008922piperinepiperine results in increased expression of NR1I2 protein23707768
C077545piperophospiperophos binds to and results in increased activity of NR1I2 protein21115097
C077545piperophospiperophos metabolite binds to and results in increased activity of NR1I2 protein21115097
C077545piperophospiperophos binds to and results in increased activity of NR1I2 protein21115097
C077545piperophospiperophos metabolite binds to and results in increased activity of NR1I2 protein21115097
C014153pirimiphos methylpirimiphos methyl binds to and results in increased activity of NR1I2 protein21115097
C006253pirinixic acidpirinixic acid results in increased expression of NR1I2 mRNA17426115|1830175
C037850PK 11195[PK 11195 co-treated with RXRA] results in increased activity of NR1I2 protein21315811
C037850PK 11195PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]21315811
C037850PK 11195PK 11195 results in increased activity of NR1I2 protein26187274
D010936Plant ExtractsNR1I2 protein affects the reaction [Plant Extracts results in increased expression of CYP3A4 mRNA]12695340
D010936Plant ExtractsPlant Extracts results in increased activity of NR1I2 protein15627040|1721044
D010936Plant ExtractsPlant Extracts binds to NR1I2 protein15792627
D010936Plant ExtractsPlant Extracts results in increased activity of NR1I2 protein14742670|2385098
D010936Plant Extracts[Plant Extracts results in increased activity of NR1I2 protein] which results in increased expression of SULT2A1 mRNA14742670
D010936Plant ExtractsPlant Extracts results in increased expression of NR1I2 mRNA23262642
D028321Plant PreparationsPlant Preparations promotes the reaction [NR1I2 protein binds to CYP1A1 promoter]21084653
C013649plastochromanol 8plastochromanol 8 binds to and results in increased activity of NR1I2 protein15269186
C013649plastochromanol 8plastochromanol 8 inhibits the reaction [NR1I2 protein binds to NCOR1 protein]15269186
C013649plastochromanol 8plastochromanol 8 results in increased activity of NR1I2 protein15649653
D059808PolyphenolsPolyphenols inhibits the reaction [Glucose results in decreased activity of NR1I2 protein]21682256
D059808PolyphenolsPolyphenols results in increased activity of NR1I2 protein21682256
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione inhibits the reaction [NR1I2 protein results in increased expression of CYP7A1 mRNA]"12705905
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione inhibits the reaction [Thapsigargin results in decreased expression of NR1I2 mRNA]"25616597
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione results in decreased activity of NR1I2 protein"12705905
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione results in increased activity of NR1I2 protein"15075359
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione promotes the reaction [NR1I2 protein binds to NCOA1 protein]"15833898
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione results in increased activity of NR1I2 protein"15075359
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione binds to and results in increased activity of NR1I2 protein"15833898
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione binds to NR1I2 protein"21309576
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione promotes the reaction [NR1I2 protein binds to NCOA1 protein]"15075359
D011277PregnanedionesPregnanediones binds to and results in increased activity of NR1I2 protein21291553
D011284PregnenoloneNR1I2 affects the reaction [Pregnenolone results in increased expression of AHR2 mRNA]25424564
D011284PregnenoloneNR1I2 affects the reaction [Pregnenolone results in increased expression of CYP3A65 mRNA]25424564
D011284PregnenoloneNR1I2 affects the reaction [Pregnenolone results in increased expression of CYP3C1 mRNA]25424564
D011284PregnenoloneNR1I2 affects the reaction [Pregnenolone results in increased expression of NR1I2 mRNA]25424564
D011284PregnenolonePregnenolone binds to and results in increased activity of NR1I2 protein25424564
D011284PregnenolonePregnenolone results in increased expression of NR1I2 mRNA25424564
D011284PregnenolonePregnenolone binds to and results in increased activity of NR1I2 protein16054614
D011284PregnenolonePregnenolone results in increased activity of NR1I2 protein15650019
D011284PregnenolonePregnenolone binds to and results in increased activity of NR1I2 protein21291553
C071461pregnenolone 16-acetonitrilepregnenolone 16-acetonitrile binds to and results in increased activity of NR1I2 protein21311750
C071461pregnenolone 16-acetonitrile[pregnenolone 16-acetonitrile binds to and results in increased activity of NR1I2 protein] which results in decreased expression of NR1I2 mRNA21311750|2131175
C071461pregnenolone 16-acetonitrile[pregnenolone 16-acetonitrile binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA21311750
C071461pregnenolone 16-acetonitrile[pregnenolone 16-acetonitrile binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A23/3A1 mRNA21311750
C071461pregnenolone 16-acetonitrilepregnenolone 16-acetonitrile results in decreased expression of NR1I2 mRNA21311750
C071461pregnenolone 16-acetonitrilepregnenolone 16-acetonitrile results in decreased expression of NR1I2 protein21311750
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein15710363
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR1I2 mRNA15914091
D011285Pregnenolone CarbonitrileNR1I2 gene promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A4 protein]18799805
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]28428138
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]]28428138
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein12370413|1869208
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25542144
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of SULT2A1 mRNA12370413
D011285Pregnenolone CarbonitrileEndotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of NR1I2 mRNA]15456840
D011285Pregnenolone CarbonitrileKetoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]16819505
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]16819505
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]16819505
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA]20371638
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]16819505
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 protein]16819505
D011285Pregnenolone CarbonitrileNR1I2 gene mutant form results in decreased susceptibility to Pregnenolone Carbonitrile16819505
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in decreased expression of AADAC mRNA]22429928
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in decreased expression of SLCO1A1 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of AKR1B7 mRNA]25949234
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ALDH1A1 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ALDH1A7 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CES2A mRNA]22429928
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CES2C mRNA]22429928
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]22496397|2594923
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA1 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA4 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM2 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM3 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of NR1I3 mRNA]25949234
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of SLCO1A4 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of SULT2A2 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of UGT1A1 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of UGT1A9 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of UGT2B34 mRNA]22496397
D011285Pregnenolone CarbonitrileNR1I2 protein affects the susceptibility to Pregnenolone Carbonitrile21920351|2242992
D011285Pregnenolone CarbonitrileNR1I2 protein affects the susceptibility to [Pregnenolone Carbonitrile co-treated with Metformin]21920351
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of ATF3 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of CCL2 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of CYP4A10 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of FOS mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of HSPA1B mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of IL1B mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of IL1RN mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of IL6 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of MME mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of PF4 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of AACS mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDC20 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDK1 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C37 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]16267138|2269881
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A44 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of FOXM1 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA2 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA4 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of HMGCR mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of KIF20A mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of RASAL1 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of SLC39A5 mRNA]22698814
D011285Pregnenolone CarbonitrileNR1I2 results in increased susceptibility to Pregnenolone Carbonitrile20371638
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to and results in increased activity of NR1I2 protein15630458|1591985
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA15833929
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 gene mutant form] results in decreased expression of PDK4 mRNA25689681
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of ABCC2 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of GSTT2 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of PAPSS2 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of SULT1E1 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of SULT3A1 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein] results in increased expression of CYP3A11 mRNA22024132
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA23707768
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 gene mutant form results in decreased expression of CYP4A10 mRNA]25689681
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]] which results in increased expression of ABCC3 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]] which results in increased expression of ALDH1A1 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]] which results in increased expression of CYP2B10 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 3' UTR]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 5' UTR]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 gene]] which results in increased expression of CYP3A11 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 intron]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP3A11 promoter]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]] which results in increased expression of GSTA1 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM2 gene]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to PAPSS2 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to PAPSS2 gene]] which results in increased expression of PAPSS2 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to SLCO1A4 5' UTR]20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to SLCO1A4 gene]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to SLCO1A4 gene]] which results in increased expression of SLCO1A4 mRNA20693526
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]12370413
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA12370413
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein12370413|1474267
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of CYP3A11 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTA1 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM2 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM3 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of SLCO1A4 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of SULT2A1 mRNA12370413|1474267
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of UGT1A1 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of UGT1A5 mRNA22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of UGT1A9 mRNA22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR1I2 mRNA28903501
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR1I2 protein19433268
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein21742782
D011285Pregnenolone Carbonitrileallyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]25069801
D011285Pregnenolone Carbonitrile"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]"21402137
D011285Pregnenolone Carbonitrile[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA25069801
D011285Pregnenolone CarbonitrileNR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23/3A1 mRNA]11752103
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to and results in increased activity of NR1I2 protein15883047
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to NR1I2 protein19562681
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23/3A1 promoter]12370413
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]12370413
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA12370413
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of NR1I2 mRNA20888898
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein19249324|2140213
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of SULT2A1 mRNA12370413
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR1I2 mRNA15596064
D011285Pregnenolone Carbonitrilesulforafan inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]21402137
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to and results in increased activity of NR1I2 protein16054614
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein21402137
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to and affects the activity of NR1I2 protein15683829
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to and results in increased activity of NR1I2 protein15833929
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile binds to NR1I2 protein22429928
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to NCOA1 protein]18692084
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased activity of NR1I2 protein22496397
C118050pretilachlorpretilachlor binds to and results in increased activity of NR1I2 protein21115097|2222339
C118050pretilachlorpretilachlor results in increased activity of NR1I2 protein16565514
C118050pretilachlorpretilachlor binds to and results in increased activity of NR1I2 protein21115097
D011343ProcaineProcaine results in increased activity of NR1I2 protein25455453
C045362prochloraz[NR1I2 protein co-treated with NR1I3 protein] affects the reaction [prochloraz results in increased expression of CYP2B10 protein]28058446
C045362prochloraz[NR1I2 protein co-treated with NR1I3 protein co-treated with prochloraz] results in increased expression of CYP1A1 mRNA28058446
C045362prochlorazprochloraz binds to and results in increased activity of NR1I2 protein21115097
C045362prochlorazprochloraz results in increased activity of NR1I2 protein16565514
C045362prochlorazprochloraz binds to and results in increased activity of NR1I2 protein21115097
C035988procymidoneprocymidone binds to and results in increased activity of NR1I2 protein21115097
C035988procymidone[procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein25028461
D011374ProgesteroneProgesterone binds to and results in increased activity of NR1I2 protein16054614
D011374Progesterone[Progesterone co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA18098064
D011374ProgesteroneProgesterone results in increased activity of NR1I2 protein15650019
D011374ProgesteroneProgesterone binds to and results in increased activity of NR1I2 protein14613717
D011374ProgesteroneProgesterone metabolite results in increased activity of NR1I2 protein15846226
D011374ProgesteroneProgesterone binds to and results in increased activity of NR1I2 protein21291553
D011374Progesterone[Progesterone co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA10707959
D011374ProgesteroneProgesterone promotes the reaction [NCOA1 protein binds to NR1I2 protein]10707959
D011374ProgesteroneProgesterone promotes the reaction [NRIP1 protein binds to NR1I2 protein]10707959
D011400PrometrynePrometryne binds to and results in increased activity of NR1I2 protein21115097
C001059pronamidepronamide binds to and results in increased activity of NR1I2 protein21115097
C001059pronamidepronamide binds to and results in increased activity of NR1I2 protein21115097
C019540propaphospropaphos binds to and results in increased activity of NR1I2 protein21115097
C019540propaphospropaphos binds to and results in increased activity of NR1I2 protein21115097
C045950propiconazolepropiconazole results in increased activity of NR1I2 protein28259787
C045950propiconazolepropiconazole binds to and results in increased activity of NR1I2 protein21115097
C045950propiconazolepropiconazole results in increased activity of NR1I2 protein16565514|2825978
C045950propiconazole[propiconazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA29420809
C045950propiconazolepropiconazole binds to and results in increased activity of NR1I2 protein21115097
D011433PropranololPropranolol results in increased activity of NR1I2 protein28259787
D011441PropylthiouracilPropylthiouracil results in increased expression of NR1I2 mRNA24780913
C032072prothiophosprothiophos binds to and results in increased activity of NR1I2 protein21115097
C032072prothiophosprothiophos binds to and results in increased activity of NR1I2 protein21115097
C107773pterostilbenepterostilbene binds to and results in increased activity of NR1I2 protein20869355
C513428pyrachlostrobinpyrachlostrobin affects the activity of NR1I2 protein23611293
D011722PyrethrinsPyrethrins binds to and results in increased activity of NR1I2 protein21115097
D011722PyrethrinsPyrethrins binds to and results in increased activity of NR1I2 protein21115097
C010418pyridafenthionpyridafenthion binds to and results in increased activity of NR1I2 protein21115097
C010418pyridafenthionpyridafenthion binds to and results in increased activity of NR1I2 protein21115097
C108337pyrimethanil"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
D011794QuercetinQuercetin binds to and results in increased activity of NR1I2 protein26238175
D011794QuercetinQuercetin results in increased activity of NR1I2 protein19034627
D011794QuercetinQuercetin results in increased activity of NR1I2 protein26238175
C009145quinalphosquinalphos binds to and results in increased activity of NR1I2 protein21115097
C009145quinalphosquinalphos binds to and results in increased activity of NR1I2 protein21115097
C470613quinoxyfen"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
C005805quintozenequintozene binds to and results in increased activity of NR1I2 protein21115097
D012110Reserpine[Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
C059514resveratrolresveratrol binds to and results in increased activity of NR1I2 protein20869355
C059514resveratrolresveratrol inhibits the reaction [NR1I2 protein results in decreased uptake of and results in decreased metabolism of Glucose]26616219
C059514resveratrolresveratrol results in increased activity of NR1I2 protein17210444|2152469
C059514resveratrol[resveratrol results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA21524698
C059514resveratrolresveratrol results in decreased activity of NR1I2 protein25341568
D015474IsotretinoinIsotretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
D015474IsotretinoinIsotretinoin results in increased activity of NR1I2 protein25455453
D015474Isotretinoin[Isotretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D012293RifampinRifampin results in increased activity of NR1I2 protein27732639
D012293Rifampin"1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]"21315811
D012293Rifampin"7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]"21315811
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]25069801
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
D012293Rifampinallyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]25069801
D012293RifampinDexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]12695351
D012293Rifampinenilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D012293Rifampin[fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D012293RifampinFluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D012293Rifampinhydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D012293RifampinINS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC mRNA]24204015
D012293RifampinItraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
D012293RifampinItraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]17998298
D012293Rifampin[Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D012293RifampinKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]23707768
D012293RifampinKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]23707768
D012293RifampinKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]23707768
D012293RifampinKetoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]23707768
D012293RifampinKetoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]17998298
D012293RifampinKetoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]16819505|1743810
D012293RifampinKetoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]21402137
D012293RifampinKetoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]16608920|1681950
D012293Rifampin[Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein20869355
D012293RifampinMiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D012293Rifampinmulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]27918128
D012293Rifampinmulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]27918128
D012293RifampinNCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]26920453
D012293RifampinNCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]26920453
D012293RifampinNCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]21292004
D012293Rifampin"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D012293RifampinNR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]18799805
D012293RifampinNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]18799805
D012293RifampinNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]18799805
D012293RifampinNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]18799805
D012293RifampinNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]18799805
D012293RifampinNR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]25313206|2828982
D012293RifampinNR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]25313206|2828982
D012293RifampinNR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]12695351
D012293RifampinNR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]14600250
D012293RifampinNR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]12695340|2174278
D012293RifampinNR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]27180241
D012293RifampinNR1I2 protein affects the susceptibility to Rifampin15670600
D012293Rifampin[NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]12072427
D012293Rifampin[NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA21764778
D012293Rifampin[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA26920453
D012293Rifampin[NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA21764778
D012293RifampinNR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]28428138
D012293RifampinNR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]25616597
D012293RifampinNR1I2 protein mutant form results in decreased susceptibility to Rifampin17438109
D012293RifampinNR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293RifampinNR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]21127053
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]26616219
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]26616219
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]20079722
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]23707768
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]23707768
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]17003103
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]21127053
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]12695351
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]17003103|2112705
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]23707768
D012293RifampinNR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]21127053
D012293RifampinNR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293RifampinNR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]25069801
D012293RifampinNR1I2 protein results in increased susceptibility to Rifampin26920453|2717777
D012293Rifampin[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA26920453
D012293Rifampin[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA27918128
D012293Rifampin[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein27918128
D012293Rifampin[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin25835148
D012293Rifampinochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]26341324
D012293Rifampinoxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]17998298
D012293Rifampinoxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]17438109
D012293Rifampinoxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
D012293RifampinPK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]21315811
D012293RifampinRifampin affects the localization of NR1I2 protein26883953
D012293RifampinRifampin binds to and results in increased activity of NR1I2 protein14977870|1548954
D012293Rifampin[Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]20041327
D012293Rifampin[Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA23845848
D012293Rifampin[Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA17696253
D012293RifampinRifampin binds to NR1I2 protein15705662|2231438
D012293Rifampin[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter15933212
D012293Rifampin[Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein22733800
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA20361990
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA20361990|2209369
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYR61 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC mRNA24204015
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA24204015
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA21127053|2420401
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein24204015
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA21127053
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA18098064
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA21127053
D012293Rifampin[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein21315811
D012293RifampinRifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]22214767
D012293RifampinRifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]22214767
D012293RifampinRifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]28289823
D012293RifampinRifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]25313206
D012293RifampinRifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]17998298
D012293RifampinRifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]17998298
D012293RifampinRifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]26883953
D012293RifampinRifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]26883953
D012293RifampinRifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]21292004
D012293RifampinRifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]21292004
D012293RifampinRifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]22214767
D012293RifampinRifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]22214767
D012293RifampinRifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]11581012|2828982
D012293RifampinRifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]11581012
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]15630458
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]16857725
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]21641981
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]21764778
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]12072427|1681950
D012293RifampinRifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]17088262
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein]12072427
D012293RifampinRifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]24204015
D012293RifampinRifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]26920453
D012293RifampinRifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]21292004
D012293RifampinRifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A23/3A1 mRNA]17483497
D012293RifampinRifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]12417264|2129200
D012293RifampinRifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
D012293RifampinRifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
D012293RifampinRifampin results in decreased acetylation of NR1I2 protein26883953
D012293RifampinRifampin results in increased activity of NR1I2 protein12065438|1241726
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]21764778
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein20624464
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA14570758
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA17041008
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008|2112705
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA22101211
D012293RifampinRifampin results in increased expression of NR1I2 mRNA22093699|2231029
D012293RifampinRifampin results in increased expression of NR1I2 protein22687401|2273380
D012293Rifampin[Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein22687401
D012293RifampinSGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC mRNA]24204015
D012293RifampinSGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]24204015
D012293Rifampinsodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]15833926
D012293Rifampintrichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]26883953
D012293RifampinNR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]20361990
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein25835148
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein25835148
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein25835148
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein25835148
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein25835148
D012293RifampinRifampin affects the localization of and results in increased activity of NR1I2 protein27806127
D012293RifampinRifampin binds to NR1I2 gene mutant form22467028
D012293Rifampin[Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA22467028
D012293Rifampin[Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA22467028
D012293RifampinRifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]12370413
D012293Rifampin[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA12370413
D012293RifampinRifampin results in increased activity of NR1I2 protein18692084
D012293RifampinRifampin binds to and results in increased activity of NR1I2 protein21742782
D012293Rifampinarsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]22159698
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA22310326
D012293RifampinRifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23/3A1 promoter]12370413
D012293RifampinRifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]12370413
D012293Rifampin[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA12370413
D012293RifampinRifampin results in increased activity of NR1I2 protein17003103
D012293RifampinRifampin results in increased localization of NR1I2 protein22159698
D012293Rifampinsodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA]22310326
D012293RifampinRifampin results in increased activity of NR1I2 protein25680588
D012293RifampinRifampin binds to and results in increased activity of NR1I2 protein18094037
D012293RifampinRifampin binds to and results in increased expression of NR1I2 protein20361990
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA18332045
D012293RifampinRifampin results in increased activity of NR1I2 protein11836020|1685772
C042734rifaximin"bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate inhibits the reaction [rifaximin results in increased activity of NR1I2 protein]"27506419
C042734rifaximinNR1I2 results in increased susceptibility to rifaximin22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased abundance of Triglycerides22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of ABCB1A mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of ACTA2 mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of APOA4 mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CD36 protein22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CFD mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CIDEC mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of COL1A1 mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CYP3A11 mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CYP7A1 protein22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CYP7B1 protein22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of DGAT2 mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of FABP2 protein22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of LTA mRNA22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of NR1H4 protein22790967
C042734rifaximin[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of PPARG mRNA22790967
C042734rifaximinrifaximin binds to and results in increased activity of NR1I2 protein22790967
C042734rifaximin[rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid21599020
C042734rifaximinrifaximin results in increased activity of NR1I2 protein27506419
C042734rifaximinrifaximin results in increased expression of NR1I2 mRNA21599020|2229195
C042734rifaximin[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]21599020
C042734rifaximin[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]21599020
C042734rifaximin[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]21599020
C042734rifaximin[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]21599020
C042734rifaximinrifaximin binds to and results in increased activity of NR1I2 protein21599020
D019782RiluzoleRiluzole results in increased activity of NR1I2 protein25455453
D018967Risperidone"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]"21402137
D018967RisperidoneRisperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21402137
D019438RitonavirRitonavir results in increased activity of NR1I2 protein27732639
D019438RitonavirRitonavir binds to and results in increased activity of NR1I2 protein14977870|1584971
D019438RitonavirRitonavir results in increased activity of NR1I2 protein27732639
C057006Ro 21-5104NR1I2 mRNA promotes the reaction [Ro 21-5104 results in increased expression of CYP2B6 mRNA]25313206
C057006Ro 21-5104NR1I2 mRNA promotes the reaction [Ro 21-5104 results in increased expression of CYP3A4 mRNA]25313206
C057006Ro 21-5104Ro 21-5104 binds to and results in increased activity of NR1I2 protein25313206
C057006Ro 21-5104Ro 21-5104 inhibits the reaction [NR1I2 protein binds to NCOR2 protein]25313206
C057006Ro 21-5104Ro 21-5104 promotes the reaction [NR1I2 protein binds to NCOA1 protein]25313206
D012500SantoninSantonin results in increased activity of NR1I2 protein25455453
D012500Santonin[Santonin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D019258SaquinavirNR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]18799805
C034557schizandrer Aschizandrer A results in increased activity of NR1I2 protein21524698
C034557schizandrer A[schizandrer A results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA21524698
C034734schizandrin Aschizandrin A binds to and results in increased activity of NR1I2 protein16267138
C034734schizandrin Aschizandrin A results in increased activity of NR1I2 protein16267138
C015499schizandrin Bschizandrin B binds to and results in increased activity of NR1I2 protein16267138
C015499schizandrin Bschizandrin B results in increased activity of NR1I2 protein16267138
C033585schizandrol Bschizandrol B binds to and results in increased activity of NR1I2 protein16267138
D012631SecobarbitalSecobarbital results in increased activity of NR1I2 protein21068194
C060283secoisolariciresinolsecoisolariciresinol results in increased activity of NR1I2 protein15885729
C009250sevofluranesevoflurane affects the expression of NR1I2 mRNA15967596
D019821SimvastatinSGK2 mutant form inhibits the reaction [[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose]24204015
D019821Simvastatin[Simvastatin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA24204015
D019821Simvastatin[Simvastatin co-treated with NR1I2 protein] results in increased expression of G6PC mRNA24204015
D019821Simvastatin[Simvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA24204015
D019821Simvastatin[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose24204015
D019821SimvastatinSimvastatin promotes the reaction [NR1I2 protein binds to SGK2 promoter]24204015
D019821SimvastatinSimvastatin results in increased activity of NR1I2 protein15802384
D019821Simvastatin[Simvastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
C017947sodium arsenitesodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]15833926
C017947sodium arsenitesodium arsenite results in increased expression of NR1I2 mRNA19084030
C017947sodium arsenitesodium arsenite results in decreased expression of NR1I2 mRNA19822182
C017947sodium arsenitesodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23/3A1 mRNA]22310326
D013148SpironolactoneNR1I2 affects the reaction [Spironolactone results in increased expression of ABCB1 protein]21459122
D013148SpironolactoneSpironolactone binds to and results in increased activity of NR1I2 protein16054614
D013148SpironolactoneSpironolactone binds to and results in increased activity of NR1I2 protein15919853
D013148Spironolactone[Spironolactone binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA15833929
D013148SpironolactoneSpironolactone results in increased expression of NR1I2 mRNA17627975
D013148SpironolactoneNR1I2 protein promotes the reaction [Spironolactone results in increased expression of CYP3A23/3A1 mRNA]11752103
D013148SpironolactoneSpironolactone binds to and results in increased activity of NR1I2 protein16054614
D013148SpironolactoneNR1I2 protein binds to Spironolactone22429928
D013148SpironolactoneSpironolactone binds to and affects the activity of NR1I2 protein15683829
D013148SpironolactoneSpironolactone binds to and results in increased activity of NR1I2 protein15833929
C100355SR 12813SR 12813 results in increased activity of NR1I2 protein27732639
C100355SR 12813allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]]25069801
C100355SR 12813NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]25069801
C100355SR 12813SR 12813 affects the localization of NR1I2 protein19746521
C100355SR 12813SR 12813 binds to and results in increased activity of NR1I2 protein22223399|2231438
C100355SR 12813[SR 12813 binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA23845848
C100355SR 12813SR 12813 binds to NR1I2 protein24819614|2787190
C100355SR 12813SR 12813 promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]17998298
C100355SR 12813SR 12813 results in increased activity of NR1I2 protein21127053|2164198
C100355SR 12813[SR 12813 results in increased activity of NR1I2 protein] which results in decreased susceptibility to Paclitaxel19746521
C100355SR 12813[SR 12813 results in increased activity of NR1I2 protein] which results in decreased susceptibility to Tamoxifen19746521
C100355SR 12813[SR 12813 results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA19746521
C100355SR 12813[SR 12813 results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA19746521|2112705
C100355SR 12813SR 12813 results in increased activity of NR1I2 protein27732639
C100355SR 12813SR 12813 results in increased activity of NR1I2 protein25680588
C110304SR 144190SR 144190 affects the activity of NR1I2 protein23611293
C012042steviolsteviol binds to and results in increased activity of NR1I2 protein28887089
C025906stilbene oxidestilbene oxide binds to and results in increased activity of NR1I2 protein20869355
D013418SulfamethazineSulfamethazine results in increased activity of NR1I2 protein12065438
D013442SulfinpyrazoneSulfinpyrazone binds to and results in increased activity of NR1I2 protein14977870
D013442SulfinpyrazoneSulfinpyrazone results in increased activity of NR1I2 protein12065438
C016766sulforafansulforafan inhibits the reaction [alpha-methylepinine results in decreased expression of NR1I2 mRNA]21871945
C016766sulforafan"N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforafan results in decreased expression of NR1I2 mRNA]"21871945
C016766sulforafan"sulforafan inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NR1I2 mRNA]"21871945
C016766sulforafansulforafan inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein]21402137
C016766sulforafansulforafan results in decreased expression of NR1I2 mRNA21402137|2187194
C560328sulfoxaflorNR1I2 gene mutant form inhibits the reaction [sulfoxaflor results in increased expression of CYP2B10 mRNA]23607986
C560328sulfoxaflorNR1I2 gene mutant form inhibits the reaction [sulfoxaflor results in increased expression of CYP3A11 mRNA]23607986
C560328sulfoxaflorNR1I2 protein results in increased susceptibility to sulfoxaflor23607986
C446685systhanesysthane results in decreased expression of NR1I2 mRNA24962053
C508967tamarixetintamarixetin binds to and results in increased activity of NR1I2 protein26238175
C508967tamarixetintamarixetin results in increased activity of NR1I2 protein26238175
D013629TamoxifenNR1I2 protein promotes the reaction [Tamoxifen results in increased expression of ABCB1 protein]20041327
D013629Tamoxifen[SR 12813 results in increased activity of NR1I2 protein] which results in decreased susceptibility to Tamoxifen19746521
D013629TamoxifenTamoxifen binds to and results in increased activity of NR1I2 protein16054614|1883917
D013629TamoxifenTamoxifen results in increased activity of NR1I2 protein20041327
D013629Tamoxifen[Tamoxifen results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
D013629TamoxifenTamoxifen results in decreased expression of NR1I2 mRNA27765674
C021751tanshinoneNR1I2 protein promotes the reaction [tanshinone results in increased expression of CYP3A4 protein]18805405
C021751tanshinonetanshinone results in increased activity of NR1I2 protein18805405
D013655Taurochenodeoxycholic AcidTaurochenodeoxycholic Acid binds to and results in increased activity of NR1I2 protein21291553
D013656Taurocholic AcidTaurocholic Acid results in increased expression of NR1I2 mRNA18706437
D013656Taurocholic AcidTaurocholic Acid results in increased expression of NR1I2 mRNA27160211
D013657Taurodeoxycholic AcidTaurodeoxycholic Acid binds to and results in increased activity of NR1I2 protein21291553
D013658Taurolithocholic AcidTaurolithocholic Acid binds to and results in increased activity of NR1I2 protein21291553
D013662TeaTea results in decreased activity of NR1I2 protein24815822
C087114tebuconazoletebuconazole results in increased activity of NR1I2 protein29420809
C087114tebuconazole[tebuconazole results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA29420809
C012568terbufosterbufos binds to and results in increased activity of NR1I2 protein21115097
C012568terbufosterbufos binds to and results in increased activity of NR1I2 protein21115097
C010347terbutryneterbutryne binds to and results in increased activity of NR1I2 protein20024649
C037565terbutylazineterbutylazine binds to and results in increased activity of NR1I2 protein20024649
D013730Terphenyl CompoundsTerphenyl Compounds binds to and results in increased activity of NR1I2 protein20869355
D013739TestosteroneTestosterone results in increased expression of NR1I2 mRNA20844152
D013739TestosteroneTestosterone binds to and results in increased activity of NR1I2 protein14613717
C020806tetrabromobisphenol Atetrabromobisphenol A binds to and results in increased activity of NR1I2 protein23714657
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased activity of NR1I2 protein25680588
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased activity of NR1I2 protein25680588
C041181tetrachlorodiantetrachlorodian binds to and results in increased activity of NR1I2 protein23714657
D013749TetrachlorodibenzodioxinNR1I2 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]28428138
D013749TetrachlorodibenzodioxinPregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]]28428138
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NR1I2 mRNA28571685
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NR1I2 mRNA24058054
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NR1I2 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NR1I2 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NR1I2 mRNA21215274|2172422
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NR1I2 mRNA20035846
C005806tetrachloroisophthalonitriletetrachloroisophthalonitrile results in increased activity of NR1I2 protein20143881
D013751TetrachlorvinphosTetrachlorvinphos binds to and results in increased activity of NR1I2 protein21115097
D013751TetrachlorvinphosTetrachlorvinphos binds to and results in increased activity of NR1I2 protein21115097
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of NR1I2 protein]18473823
C018674tetrahydrofuranNR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]28495613
C018674tetrahydrofuranNR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP2B10 mRNA]28495613
C009424tetramethrinCES2 protein inhibits the reaction [tetramethrin results in increased activity of NR1I2 protein]19249324
C009424tetramethrintetramethrin results in increased activity of NR1I2 protein19249324
C009424tetramethrintetramethrin results in increased activity of NR1I2 protein19249324
D013792ThalidomideThalidomide results in increased expression of NR1I2 mRNA28496040
D019284ThapsigarginNR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]25616597
D019284Thapsigargin"pregna-4,17-diene-3,16-dione inhibits the reaction [Thapsigargin results in decreased expression of NR1I2 mRNA]"25616597
D019284ThapsigarginThapsigargin promotes the reaction [CEBPB protein binds to NR1I2 promoter]25616597
D019284ThapsigarginThapsigargin promotes the reaction [HNF4A protein binds to NR1I2 promoter]25616597
D019284ThapsigarginThapsigargin results in decreased expression of NR1I2 mRNA25616597
D019284ThapsigarginThapsigargin results in decreased expression of NR1I2 protein25616597
D013827ThiabendazoleThiabendazole results in increased activity of NR1I2 protein25455453
C091707thiazopyrthiazopyr results in increased activity of NR1I2 protein20143881
D013853ThioacetamideThioacetamide results in decreased expression of NR1I2 mRNA23411599|2622270
D013859ThiocarbamatesNR1I2 protein promotes the reaction [Thiocarbamates results in increased expression of CYP3A4 mRNA]17293382
D013974ThyroxineThyroxine results in increased activity of NR1I2 protein25455453
D013974Thyroxine[Thyroxine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D013974Thyroxine[Dichlorodiphenyl Dichloroethylene co-treated with Thyroxine] results in increased expression of NR1I2 mRNA16764480
D013974ThyroxineThyroxine results in increased expression of NR1I2 mRNA16764480
C013713thymol bluethymol blue binds to and results in increased activity of NR1I2 protein20869355
D013944ThymolphthaleinThymolphthalein binds to and results in decreased activity of NR1I2 protein20869355
C021270tiaprofenic acidtiaprofenic acid results in increased activity of NR1I2 protein25455453
C048166tiracizinetiracizine binds to and results in increased activity of NR1I2 protein28289823
C423915TO-901317NR1H3 protein inhibits the reaction [[TO-901317 co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]23732298
C423915TO-901317RXRA protein promotes the reaction [[TO-901317 co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA]23732298
C423915TO-901317TO-901317 binds to and results in increased activity of NR1I2 protein21291553
C423915TO-901317TO-901317 binds to NR1I2 protein28289823
C423915TO-901317[TO-901317 co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA23732298
C423915TO-901317TO-901317 promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]27551952
C423915TO-901317TO-901317 results in increased activity of NR1I2 protein21227907|2389947
C423915TO-901317TO-901317 binds to and results in increased activity of NR1I2 protein21291553
C423915TO-901317TO-901317 results in increased activity of NR1I2 protein23899473
C423915TO-901317TO-901317 results in increased activity of NR1I2 protein23899473
C423915TO-901317TO-901317 binds to and results in increased activity of NR1I2 protein21291553
C082032tocotrienol, alpha"tocotrienol, alpha binds to and results in increased activity of NR1I2 protein"15269186
C082032tocotrienol, alpha"tocotrienol, alpha inhibits the reaction [NR1I2 protein binds to NCOR1 protein]"15269186
C082089tocotrienol, beta"tocotrienol, beta binds to and results in increased activity of NR1I2 protein"15269186
C082089tocotrienol, beta"tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein]"15269186
C082097tocotrienol, delta"tocotrienol, delta binds to and results in increased activity of NR1I2 protein"15269186
C082097tocotrienol, delta"tocotrienol, delta inhibits the reaction [NR1I2 protein binds to NCOR1 protein]"15269186
C426783tolclofos-methyltolclofos-methyl binds to and results in increased activity of NR1I2 protein21115097
C052342topiramatetopiramate results in increased activity of NR1I2 protein14636322
D014112ToxapheneToxaphene results in increased activity of NR1I2 protein16565514|2568058
D014112ToxapheneToxaphene results in increased activity of NR1I2 protein25680588
C035705tralomethrintralomethrin binds to and results in increased activity of NR1I2 protein21115097
C035705tralomethrintralomethrin binds to and results in increased activity of NR1I2 protein21115097
C411671TRAM 34TRAM 34 binds to and results in increased activity of NR1I2 protein20869355
D014212TretinoinTretinoin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]16632523
D014212TretinoinTretinoin results in increased activity of NR1I2 protein25455453
D014212Tretinoin[Tretinoin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
C072782tri-(2-chloroisopropyl)phosphatetri-(2-chloroisopropyl)phosphate results in increased activity of NR1I2 protein24051214
C032910triadimefon"[N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with pyrimethanil co-treated with Fenitrothion co-treated with triadimefon co-treated with quinoxyfen co-treated with penconazole] results in increased activity of NR1I2 protein"25028461
C032910triadimefontriadimefon binds to and results in increased activity of NR1I2 protein21115097
C032910triadimefontriadimefon binds to and results in increased activity of NR1I2 protein21115097
C032910triadimefontriadimefon results in decreased expression of NR1I2 mRNA24962053
C533760tribromodiphenyl ether 28tribromodiphenyl ether 28 results in increased activity of NR1I2 protein25680588
C039783tributyl citratetributyl citrate promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]21742782
C039783tributyl citratetributyl citrate results in increased activity of NR1I2 protein21742782
C009524tributyl phosphatetributyl phosphate results in increased activity of NR1I2 protein24051214|2677835
C011559tributyltintributyltin inhibits the reaction [Colforsin results in increased expression of NR1I2 mRNA]20211155
C012589trichostatin ARifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]26883953
C012589trichostatin ARifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]26883953
C012589trichostatin Atrichostatin A affects the localization of NR1I2 protein26883953
C012589trichostatin Atrichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]26883953
C012589trichostatin Atrichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]26883953
C012589trichostatin Atrichostatin A promotes the reaction [[PIAS1 protein co-treated with SUMO3 protein] results in increased sumoylation of NR1I2 protein]26883953
C012589trichostatin Atrichostatin A results in decreased ubiquitination of NR1I2 protein26883953
C012589trichostatin Atrichostatin A results in increased acetylation of NR1I2 protein26883953
C012589trichostatin Atrichostatin A results in increased expression of NR1I2 mRNA15901671
D014260TriclosanTriclosan binds to and results in increased activity of NR1I2 protein16054614
D014260TriclosanTriclosan results in increased activity of NR1I2 protein15885729|2389947
C053549triflumizoltriflumizol binds to and results in increased activity of NR1I2 protein21115097
C053549triflumizoltriflumizol binds to and results in increased activity of NR1I2 protein21115097
D014274TrifluralinTrifluralin binds to and results in increased activity of NR1I2 protein21115097
D014274TrifluralinTrifluralin binds to and results in increased activity of NR1I2 protein21115097
D014274TrifluralinTrifluralin binds to and results in increased activity of NR1I2 protein14613717
D014274TrifluralinTrifluralin binds to and results in increased activity of NR1I2 protein16054614
D014271TrifluridineTrifluridine results in increased activity of NR1I2 protein25455453
D014271Trifluridine[Trifluridine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
C012591triforinetriforine binds to and results in increased activity of NR1I2 protein21115097
C012591triforinetriforine binds to and results in increased activity of NR1I2 protein21115097
D014280Triglycerides[NR1I2 results in increased susceptibility to rifaximin] which results in increased abundance of Triglycerides22790967
C100146trimethobenzamidetrimethobenzamide results in increased activity of NR1I2 protein25455453
D014302Trinitrobenzenesulfonic Acid"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid"21599020
D014302Trinitrobenzenesulfonic Acid[rifaximin binds to and results in increased activity of NR1I2 protein] which results in decreased susceptibility to Trinitrobenzenesulfonic Acid21599020
D014302Trinitrobenzenesulfonic Acid"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]"21599020
D014302Trinitrobenzenesulfonic Acid"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]"21599020
D014302Trinitrobenzenesulfonic Acid"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]"21599020
D014302Trinitrobenzenesulfonic Acid"[cholan-2,3,24-tryl-2,3,24-trisulfate binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]"21599020
D014302Trinitrobenzenesulfonic Acid[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCL3 protein]21599020
D014302Trinitrobenzenesulfonic Acid[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]21599020
D014302Trinitrobenzenesulfonic Acid[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MPO protein]21599020
D014302Trinitrobenzenesulfonic Acid[rifaximin binds to and results in increased activity of NR1I2 protein] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]21599020
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of NR1I2 mRNA21829567
C005445triphenyl phosphatetriphenyl phosphate metabolite results in increased activity of NR1I2 protein26778350
C005445triphenyl phosphatetriphenyl phosphate results in increased activity of NR1I2 protein24051214|2677835
C005445triphenyl phosphate"[tris(1,3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with Tritolyl Phosphates] results in increased activity of NR1I2 protein"29112739
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased activity of NR1I2 protein"24051214|2677835
C016805tris(1,3-dichloro-2-propyl)phosphate"[tris(1,3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with Tritolyl Phosphates] results in increased activity of NR1I2 protein"29112739
C000610787tris(1-chloro-2-propyl)phosphatetris(1-chloro-2-propyl)phosphate results in increased activity of NR1I2 protein26778350
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of NR1I2 mRNA29024780
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate metabolite results in increased activity of NR1I2 protein26778350
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in increased activity of NR1I2 protein24051214|2677835
C049232tris(2-ethylhexyl)phosphatetris(2-ethylhexyl)phosphate results in increased activity of NR1I2 protein24051214
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate results in increased expression of NR1I2 mRNA27776230
D014317Tritolyl PhosphatesTritolyl Phosphates results in increased activity of NR1I2 protein24051214
D014317Tritolyl Phosphates"[tris(1,3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with Tritolyl Phosphates] results in increased activity of NR1I2 protein"29112739
D014320Trityl CompoundsTrityl Compounds binds to and results in increased activity of NR1I2 protein20869355
C057693troglitazone[troglitazone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA17041008
D014217TroleandomycinTroleandomycin results in increased activity of NR1I2 protein27732639
D014217TroleandomycinTroleandomycin binds to and results in increased activity of NR1I2 protein15039302
C113580U 0126U 0126 binds to NR1I2 protein24819614
C113580U 0126U 0126 results in increased expression of NR1I2 mRNA24819614
D014501UraniumUranium results in increased expression of NR1I2 mRNA16039771
D014520UrethaneUrethane results in decreased expression of NR1I2 mRNA28818685
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of NR1I2 mRNA18706437
D014580Ursodeoxycholic AcidNFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of NR1I2 mRNA]18687751
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of NR1I2 mRNA18687751|2558270
D014635Valproic Acid[Valproic Acid co-treated with NR1I2 protein] results in increased expression of CYP24A1 mRNA21115105
D014635Valproic AcidValproic Acid results in decreased methylation of NR1I2 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of NR1I2 mRNA25084468
D014635Valproic AcidValproic Acid results in increased expression of NR1I2 mRNA27765674
D014635Valproic AcidValproic Acid results in increased expression of NR1I2 mRNA15901671
D014700VerapamilVerapamil results in increased activity of NR1I2 protein25455453
D014700Verapamil[Verapamil results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA25455453
D014740VidarabineVidarabine results in increased activity of NR1I2 protein25455453
D014747VinblastineNR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]20041327
D014747VinblastineVinblastine results in increased activity of NR1I2 protein20041327
D014747Vinblastine[Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
C025643vinclozolinvinclozolin results in increased activity of NR1I2 protein25680588
C025643vinclozolinvinclozolin binds to and results in increased activity of NR1I2 protein14613717
C025643vinclozolinvinclozolin binds to and results in increased activity of NR1I2 protein16054614
D014750VincristineNR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]20041327
D014750VincristineVincristine results in increased activity of NR1I2 protein20041327
D014750Vincristine[Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA20041327
C029297vinylidene chloridevinylidene chloride results in increased expression of NR1I2 mRNA26682919
D014807Vitamin DVitamin D analog results in increased activity of NR1I2 protein15885729
D014810Vitamin EVitamin E binds to NR1I216008107
D014812Vitamin KVitamin K results in increased activity of NR1I2 protein15876748
D024482Vitamin K 2PROX1 protein inhibits the reaction [Vitamin K 2 results in increased activity of NR1I2 protein]22023334
D024482Vitamin K 2Vitamin K 2 results in increased activity of NR1I2 protein22023334
D024482Vitamin K 2Vitamin K 2 binds to NR1I2 protein21561094
D065819Voriconazole[NR1I2 protein co-treated with NR1I3 protein] affects the metabolism of Voriconazole23274663
C574123walrycin ANR1I2 protein affects the reaction [walrycin A results in increased expression of CYP3A4 mRNA]22314385
C574123walrycin Awalrycin A binds to and results in increased activity of NR1I2 protein22314385
C574123walrycin Awalrycin A metabolite binds to NR1I2 protein22314385
D014859WarfarinWarfarin results in increased expression of NR1I2 mRNA25094061
D014859WarfarinWarfarin binds to and results in increased activity of NR1I2 protein20735727
D014859Warfarin[Warfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP2C9 mRNA20735727
D014859Warfarin[Warfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA20735727
C029659zearalenolzearalenol binds to and results in increased activity of NR1I2 protein22223399

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000976transcription regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IDA11114890  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001076transcription factor activity, RNA polymerase II transcription factor binding-IBA21873635  
GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IDA11114890  
GO:0003700DNA-binding transcription factor activityCONTRIBUTES_TOIBA21873635  
GO:0003707steroid hormone receptor activity-IEA-  
GO:0003713transcription coactivator activity-TAS9727070  
GO:0004879nuclear receptor activity-IBA21873635  
GO:0004879nuclear receptor activity-IDA12578355  
GO:0005515protein binding-IPI12578355  20413580  22939624  23602807  
GO:0008134transcription factor binding-IBA21873635  
GO:0008144drug binding-IDA12578355  
GO:0008270zinc ion binding-IEA-  
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity-IBA21873635  
GO:0098531transcription factor activity, direct ligand regulated sequence-specific DNA binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0006805xenobiotic metabolic process-IDA12578355  
GO:0007165signal transduction-TAS9784494  
GO:0007275multicellular organism development-IBA21873635  
GO:0008202steroid metabolic process-TAS9784494  
GO:0018130heterocycle biosynthetic process-IBA21873635  
GO:0019438aromatic compound biosynthetic process-IBA21873635  
GO:0030154cell differentiation-IBA21873635  
GO:0030522intracellular receptor signaling pathway-IEA-  
GO:0042738exogenous drug catabolic process-IDA12578355  
GO:0042908xenobiotic transport-IDA12578355  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO:0045892negative regulation of transcription, DNA-templated-IDA11891224  
GO:0045893positive regulation of transcription, DNA-templated-IDA12578355  
GO:0045944positive regulation of transcription by RNA polymerase II-IBA21873635  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA11114890  
GO:0046618drug export-IDA12578355  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0016604nuclear body-IDA-  
GO:0045111intermediate filament cytoskeleton-IDA-  
GO:0090575RNA polymerase II transcription factor complex-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21954916Variants of the human NR1I2 (PXR) locus in chronic periodontitis. (2012 Apr)Folwaczny MJ Periodontal Res
21245992Polymorphisms in NF-kappaB, PXR, LXR, PPARgamma and risk of inflammatory bowel disease. (2011 Jan 14)Andersen VWorld J Gastroenterol
20836841Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes. (2010 Sep 13)Andersen VBMC Cancer
23492909Pharmacogenetics of CYP1A2 activity and inducibility in smokers and exsmokers. (2013 May)Dobrinas MPharmacogenet Genomics