Gene: CCKBR

887
CCK-B|CCK2R|GASR
cholecystokinin B receptor
protein-coding
11p15.4
Ensembl:ENSG00000110148 MIM:118445 Vega:OTTHUMG00000133380 UniprotKB:P32239
NG_030591.1
PubMed
0   ANCO-SNPs
AD
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.436e-2 (AD)  3.617e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LINGO10.945
RAB150.944
STX1A0.934
CACNG30.934
SLC30A30.93
GABRD0.927
SLC8A20.927
CACNG80.927
STX1B0.926
DOC2A0.926

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SNHG18-0.619
WWTR1-0.601
YES1-0.593
REST-0.591
RBPMS-0.579
HEY2-0.569
FAM89A-0.554
CLEC2B-0.55
CNN2-0.547
RAB13-0.542

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00183PentagastrinSmall Molecule5534-95-2ApprovedTarget
DB08862CholecystokininSmall Molecule9011-97-6Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0746811-(4-bromophenylaminocarbonyl)-4,5-diphenyl-3-pyrazolidinone"1-(4-bromophenylaminocarbonyl)-4,5-diphenyl-3-pyrazolidinone binds to and results in decreased activity of CCKBR protein"21664492
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of CCKBR mRNA16788091
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C0900198-sulfocholecystokinin octapeptide8-sulfocholecystokinin octapeptide binds to CCKBR protein21728335
C095427A 86929A 86929 binds to CCKBR protein8558425
D000242Cyclic AMPCCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP]11880531
C109755AG-041RAG-041R binds to and results in decreased activity of CCKBR protein10461356|1243855
D020875Enkephalin, Ala(2)-MePhe(4)-Gly(5)-"CCKBR protein affects the susceptibility to Enkephalin, Ala(2)-MePhe(4)-Gly(5)-"11880531
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CCKBR mRNA16483693
D000661AmphetamineCCKBR protein affects the susceptibility to Amphetamine11403953|1170209
D000701Analgesics, Opioid"[CCK protein alternative form results in increased activity of CCKBR protein] which results in decreased susceptibility to Analgesics, Opioid"11880531
D001058ApomorphineCCKBR protein affects the susceptibility to Apomorphine11702094
C084553BC 264BC 264 binds to and results in increased activity of CCKBR protein8090802
C487081belinostatbelinostat results in decreased expression of CCKBR mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCKBR mRNA18164116
D004958EstradiolESR1 protein affects the reaction [Estradiol results in increased expression of CCKBR mRNA]15223131
D004958EstradiolEstradiol results in increased expression of CCKBR mRNA15223131
C006780bisphenol Abisphenol A results in increased expression of CCKBR mRNA15223131
C006780bisphenol AESR1 protein affects the reaction [bisphenol A results in increased expression of CCKBR mRNA]15223131
C006780bisphenol Abisphenol A results in decreased methylation of CCKBR promoter27312807
C006780bisphenol Abisphenol A results in decreased expression of CCKBR mRNA25181051|2710353
C018475butyraldehydebutyraldehyde results in increased expression of CCKBR mRNA26079696
D002392CatechinCatechin affects the phosphorylation of CCKBR protein15134381
D013758TetragastrinTetragastrin binds to and results in increased activity of CCKBR protein12073167
D013758TetragastrinTetragastrin binds to CCKBR protein21728335
D002713ChlorineChlorine results in decreased expression of CCKBR mRNA18636392
D002713Chlorine[Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA18636392
D002766CholecystokininCholecystokinin results in increased activity of CCKBR protein17482476
C049128cholecystokinin pentapeptidecholecystokinin pentapeptide binds to and results in increased activity of CCKBR protein9922984
D003024ClozapineClozapine results in increased expression of CCKBR mRNA17266109
C018021cobaltous chlorideCCKBR protein promotes the reaction [cobaltous chloride results in increased expression of GAST mRNA]22593272
D003042CocaineCocaine results in decreased expression of CCKBR mRNA18000554
D003042CocaineCCKBR protein results in increased susceptibility to Cocaine11403953
C116183CR 2945CR 2945 binds to and results in decreased activity of CCKBR protein19153190
D003471CuprizoneCuprizone results in decreased expression of CCKBR mRNA26577399
D003561CytarabineCytarabine results in decreased expression of CCKBR mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of CCKBR mRNA23640034
D003907DexamethasoneDexamethasone results in decreased expression of CCKBR mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of CCKBR mRNA]20032058
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CCKBR mRNA15620428
D004026DieldrinDieldrin results in increased expression of CCKBR mRNA20682304
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCKBR mRNA18164116
C118739entinostatentinostat results in decreased expression of CCKBR mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of CCKBR gene16495775
C013550gastrin 17[gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC217704804
C013550gastrin 17[gastrin 17 co-treated with CCKBR protein] results in decreased expression of BIRC317704804
C013550gastrin 17[gastrin 17 co-treated with CCKBR protein] results in increased expression of IER3 mRNA17704804
D019833GenisteinGenistein results in increased expression of CCKBR mRNA21782745
C111554GV 150013XGV 150013X binds to and results in decreased activity of CCKBR protein9922984
C058121L 365260L 365260 binds to and results in decreased activity of CCKBR protein15623601|2438541
D007854LeadLead affects the expression of CCKBR mRNA28903495
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CCKBR mRNA25613284
C042720mercuric bromidemercuric bromide results in decreased expression of CCKBR mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
D009020MorphineCCKBR protein affects the susceptibility to Morphine11403953|1188053
D009853Omeprazole[Omeprazole co-treated with CCKBR protein] results in increased expression of IER317704804
D010100OxygenCCKBR protein promotes the reaction [Oxygen deficiency results in increased expression of GAST mRNA]22593272
D010126Ozone[Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA18636392
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C496932panobinostatpanobinostat results in decreased expression of CCKBR mRNA26272509
D010269ParaquatParaquat results in decreased expression of CCKBR mRNA17077588
C065599PD 134308PD 134308 binds to and results in decreased activity of CCKBR protein8199346
C077645PD 136450PD 136450 binds to and results in decreased activity of CCKBR protein21116686|7569754
D020881Enkephalin, D-Penicillamine (2,5)-"CCKBR protein affects the susceptibility to Enkephalin, D-Penicillamine (2,5)-"11880531
D010418PentagastrinPentagastrin binds to and results in increased activity of CCKBR protein10481831|1207316
C046012pentanalpentanal results in increased expression of CCKBR mRNA26079696
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of CCKBR mRNA20136073
D010622PhencyclidinePhencyclidine results in increased expression of CCKBR mRNA17266109
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of CCKBR mRNA26272509
D010852PicrotoxinPicrotoxin results in increased expression of CCKBR mRNA15170462
C006253pirinixic acidpirinixic acid results in decreased expression of CCKBR mRNA20813756
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of CCKBR mRNA21334430
D011441PropylthiouracilPropylthiouracil results in increased expression of CCKBR mRNA24780913
C047726quineloraneCCKBR protein affects the reaction [[quinelorane binds to and results in increased activity of DRD2 protein] which results in decreased abundance of Cyclic AMP]11880531
C059514resveratrolresveratrol affects the phosphorylation of CCKBR protein15134381
C009250sevofluranesevoflurane affects the expression of CCKBR mRNA15967596
D012999SomanSoman results in increased expression of CCKBR mRNA19281266
D013449SulfonamidesSulfonamides analog binds to and results in decreased activity of CCKBR protein19811913
D013469SulpirideCCKBR protein affects the susceptibility to Sulpiride11403953
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of CCKBR mRNA]20032058
C011559tributyltintributyltin results in increased expression of CCKBR mRNA27614199
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of CCKBR mRNA24935251|2627250
D017974Uranium CompoundsUranium Compounds results in increased expression of CCKBR mRNA19654044
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CCKBR mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of CCKBR mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in increased expression of CCKBR mRNA23179753|2800136
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of CCKBR gene25560391
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA"27188386
C111237vorinostatvorinostat results in decreased expression of CCKBR mRNA26272509
C104428YF 476YF 476 binds to and results in decreased activity of CCKBR protein15940630

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004951cholecystokinin receptor activity-IDA7681836  
GO:0005515protein binding-IPI16963136  23597562  25416956  
GO:0015054gastrin receptor activity-IDA7681836  10913157  
GO:0017046peptide hormone binding-IPI7681836  
GO:0031741type B gastrin/cholecystokinin receptor binding-IDA1280419  8185642  
GO:00469351-phosphatidylinositol-3-kinase regulator activity-TAS10400698  
GO ID GO Term Qualifier Evidence PubMed
GO:0001696gastric acid secretion-IEA-  
GO:0007166cell surface receptor signaling pathway-NAS10913157  
GO:0007186G-protein coupled receptor signaling pathway-TAS-  
GO:0007200phospholipase C-activating G-protein coupled receptor signaling pathway-IDA7681836  
GO:0007204positive regulation of cytosolic calcium ion concentration-IDA10913157  
GO:0008283cell proliferation-TAS10400698  
GO:0008284positive regulation of cell proliferation-IDA10913157  
GO:0038188cholecystokinin signaling pathway-IDA7681836  
GO:0043551regulation of phosphatidylinositol 3-kinase activity-IEA-  
GO:0048565digestive tract development-IEA-  
GO:0048732gland development-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
hsa04020Calcium signaling pathway
hsa04080Neuroactive ligand-receptor interaction
hsa04971Gastric acid secretion
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-373076Class A/1 (Rhodopsin-like receptors)TAS
R-HSA-375276Peptide ligand-binding receptorsTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-416476G alpha (q) signalling eventsTAS
R-HSA-500792GPCR ligand bindingTAS
R-HSA-881907Gastrin-CREB signalling pathway via PKC and MAPKTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
12198366Investigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism. (2002 Aug)Okubo TAlcohol Clin Exp Res
11513220Polymorphisms of the CCK, CCKAR and CCKBR genes: an association with alcoholism study. (2001 Jul)Okubo TJ Stud Alcohol
26608796Variants Near CCK Receptors are Associated With Electrophysiological Responses to Pre-pulse Startle Stimuli in a Mexican American Cohort. (2015 Dec)Norden-Krichmar TMTwin Res Hum Genet
11368834No association of CCK and CCK(B) receptor polymorphisms with alcohol dependence. (2001 May 10)Vanakoski JPsychiatry Res
8986225Investigation of genetic risk factors associated with alcoholism. (1996 Dec)Harada SAlcohol Clin Exp Res