| C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of SPHK1 mRNA | 19933214 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "2,4,5,2',4',5'-hexachlorobiphenyl affects the phosphorylation of and affects the activity of SPHK1 protein" | 27318803 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "SPHK1 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of GJA1 protein]" | 27318803 |
| C525025 | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol inhibits the reaction [VEGFA protein results in increased activity of SPHK1 protein] | 17065523 |
| C525025 | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol results in decreased activity of SPHK1 protein | 17065523 |
| C525025 | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol | 4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol results in decreased activity of SPHK1 protein | 17065523 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of SPHK1 mRNA | 22230336 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of SPHK1 mRNA | 29067470 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of SPHK1 mRNA | 17562736 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein] | 21998146 |
| D020106 | Acrylamide | Acrylamide results in increased expression of SPHK1 mRNA | 28959563 |
| C016601 | afimoxifene | SPHK1 results in decreased susceptibility to afimoxifene | 21233418 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of SPHK1 mRNA | 22100608|2715375 |
| D015766 | Albendazole | [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA | 16861626 |
| D000535 | Aluminum | [APP protein modified form binds to Aluminum] which results in increased expression of SPHK1 mRNA | 21298039 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SPHK1 mRNA | 16483693 |
| C106407 | ampelopsin | ampelopsin results in decreased activity of SPHK1 protein | 22251058 |
| C106407 | ampelopsin | ampelopsin results in decreased expression of SPHK1 protein | 22251058 |
| D047310 | Apigenin | Apigenin inhibits the reaction [Lipopolysaccharides results in increased expression of SPHK1 protein] | 25557508 |
| D001151 | Arsenic | Arsenic affects the methylation of SPHK1 gene | 25304211 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite affects the expression of SPHK1 mRNA" | 25757056 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in increased expression of SPHK1 mRNA" | 18687144 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene metabolite results in increased expression of SPHK1 mRNA | 26314263 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SPHK1 mRNA | 21569818|2222880 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SPHK1 mRNA" | 20382639 |
| D004958 | Estradiol | Estradiol affects the expression of SPHK1 mRNA | 22574217 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of SPHK1 mRNA | 29275510 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of SPHK1 mRNA | 25181051 |
| D000069286 | Bortezomib | Bortezomib results in decreased expression of SPHK1 protein | 21195056 |
| D020001 | 1-Butanol | 1-Butanol inhibits the reaction [C5 protein results in increased activity of SPHK1 protein] | 19284563 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of SPHK1 mRNA | 15336504 |
| C584509 | C646 compound | C646 compound results in decreased expression of SPHK1 mRNA | 26191083 |
| D002104 | Cadmium | Cadmium results in increased expression of SPHK1 mRNA | 21120746|2437683 |
| C055494 | caffeic acid phenethyl ester | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPHK1 mRNA | 20360939 |
| D002118 | Calcium | [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium | 19284563|1934629 |
| D002118 | Calcium | resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] | 19284563|1934629 |
| D002118 | Calcium | [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium | 19346296 |
| D002118 | Calcium | resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] | 19346296 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SPHK1 mRNA | 17341687 |
| C495817 | CC-8490 | CC-8490 results in increased expression of SPHK1 mRNA | 15604281 |
| D002509 | Cephaloridine | Cephaloridine results in increased expression of SPHK1 mRNA | 18500788 |
| D002518 | Ceramides | Ceramides results in decreased activity of SPHK1 protein | 16281067 |
| D002518 | Ceramides | [resveratrol affects the localization of and results in decreased activity of SPHK1 protein] which results in increased abundance of Ceramides | 26045781 |
| D002518 | Ceramides | SPHK1 protein affects the abundance of Ceramides | 21500096 |
| D002518 | Ceramides | SPHK1 protein results in increased metabolism of Ceramides | 21500096 |
| D002518 | Ceramides | [SPHK1 protein results in increased metabolism of Ceramides] which results in increased chemical synthesis of sphingosine 1-phosphate | 21500096 |
| D020245 | p-Chloromercuribenzoic Acid | p-Chloromercuribenzoic Acid results in increased expression of SPHK1 mRNA | 26272509 |
| D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPHK1 mRNA | 20938992 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of SPHK1 mRNA | 19320972|2631426 |
| D009243 | NAD | NAD results in decreased activity of SPHK1 protein | 20518072 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased expression of SPHK1 mRNA | 19549813 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of SPHK1 mRNA | 25562108|2798913 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of SPHK1 mRNA | 19770486 |
| D003630 | Daunorubicin | Daunorubicin affects the expression of SPHK1 | 18283525 |
| D003630 | Daunorubicin | SPHK1 affects the susceptibility to Daunorubicin | 18283525 |
| C014347 | decitabine | decitabine results in increased expression of SPHK1 mRNA | 19194470 |
| D003907 | Dexamethasone | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SPHK1 mRNA | 16054899 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of SPHK1 mRNA | 22733784 |
| D003976 | Diazinon | Diazinon results in increased methylation of SPHK1 gene | 22964155 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of SPHK1 mRNA | 17361019|2126653 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in decreased expression of SPHK1 mRNA | 27392435 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of SPHK1 mRNA | 27392435 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of SPHK1 mRNA | 22023808 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of SPHK1 mRNA | 25016146 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of SPHK1 mRNA | 20360939 |
| D019813 | 1,2-Dimethylhydrazine | "1,2-Dimethylhydrazine results in increased expression of SPHK1 mRNA" | 27840820 |
| C521792 | DMU-212 | DMU-212 affects the expression of SPHK1 mRNA | 26428916 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of SPHK1 mRNA | 17351261 |
| C411675 | F 12509A | F 12509A results in decreased expression of SPHK1 protein | 16281067 |
| D000068876 | Fingolimod Hydrochloride | SPHK1 protein results in increased phosphorylation of Fingolimod Hydrochloride | 26719367 |
| D000068876 | Fingolimod Hydrochloride | [SPHK1 protein results in increased phosphorylation of Fingolimod Hydrochloride] which results in increased abundance of Fingolimod Hydrochloride metabolite | 26719367 |
| D005492 | Folic Acid | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPHK1 mRNA | 20938992 |
| C069837 | fullerene C60 | fullerene C60 results in increased expression of SPHK1 mRNA | 19167457 |
| C056933 | fumonisin B1 | fumonisin B1 inhibits the reaction [Particulate Matter results in increased expression of SPHK1 mRNA] | 27376354 |
| C056933 | fumonisin B1 | fumonisin B1 inhibits the reaction [Vehicle Emissions results in increased expression of SPHK1 mRNA] | 27376354 |
| C039281 | furan | furan results in increased expression of SPHK1 mRNA | 27387713 |
| D005947 | Glucose | Acetylcysteine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein] | 21998146 |
| D005947 | Glucose | Glucose results in increased expression of and results in increased activity of SPHK1 protein | 21998146 |
| D005947 | Glucose | Glucose results in increased expression of SPHK1 mRNA | 21998146 |
| D005947 | Glucose | "N,N-dimethylsphingosine inhibits the reaction [Glucose results in increased activity of SPHK1 protein]" | 21998146 |
| D005947 | Glucose | Pyridoxamine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein] | 21998146 |
| D005947 | Glucose | SPHK1 mRNA affects the reaction [Glucose results in increased expression of FN1 protein] | 21998146 |
| D005947 | Glucose | SPHK1 protein inhibits the reaction [Glucose results in increased expression of FN1 protein] | 21998146 |
| D017313 | Fenretinide | Fenretinide results in increased expression of SPHK1 mRNA | 28973697 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SPHK1 mRNA | 25613284 |
| C051890 | irinotecan | irinotecan affects the expression of SPHK1 mRNA | 20097248 |
| D015056 | 1-Methyl-3-isobutylxanthine | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SPHK1 mRNA | 16054899 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of SPHK1 mRNA | 20003209 |
| D007559 | Ivermectin | [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA | 16861626 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in decreased expression of SPHK1 mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of SPHK1 mRNA | 24796395 |
| D007654 | Ketoconazole | Ketoconazole results in increased expression of SPHK1 mRNA | 25787151 |
| D008070 | Lipopolysaccharides | Apigenin inhibits the reaction [Lipopolysaccharides results in increased expression of SPHK1 protein] | 25557508 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of SPHK1 mRNA | 16415329 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of SPHK1 protein | 25557508 |
| D008070 | Lipopolysaccharides | Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SPHK1 mRNA] | 16415329 |
| C106335 | macrophage stimulatory lipopeptide 2 | [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of SPHK1 mRNA | 18832182 |
| D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPHK1 mRNA | 20938992 |
| D008727 | Methotrexate | Methotrexate results in decreased expression of SPHK1 mRNA | 17400583 |
| C030957 | methylmercury II | methylmercury II results in decreased expression of SPHK1 mRNA | 26314263 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in increased expression of SPHK1 mRNA | 17412507 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased activity of SPHK1 protein | 24399507 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium results in decreased expression of SPHK1 mRNA | 24399507 |
| D015655 | 1-Methyl-4-phenylpyridinium | sphingosine 1-phosphate inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SPHK1 mRNA] | 24399507 |
| D015655 | 1-Methyl-4-phenylpyridinium | sphingosine 1-phosphate inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SPHK1 protein] | 24399507 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Progesterone results in increased expression of SPHK1 mRNA] | 17164439 |
| C583365 | N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide | "N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of SPHK1 mRNA" | 29244179 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of SPHK1 mRNA" | 25511174 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon affects the expression of SPHK1 mRNA" | 23845593|2555468 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog affects the expression of SPHK1 mRNA" | 25554681 |
| C031721 | naphthalene | naphthalene results in increased expression of SPHK1 mRNA | 18978301 |
| D009532 | Nickel | Nickel results in increased expression of SPHK1 mRNA | 12540486 |
| C029938 | nickel sulfate | [macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of SPHK1 mRNA | 18832182 |
| C029938 | nickel sulfate | nickel sulfate results in increased expression of SPHK1 mRNA | 18832182 |
| C061800 | N,N-dimethylsphingosine | "N,N-dimethylsphingosine results in decreased activity of SPHK1 protein" | 17065523 |
| C061800 | N,N-dimethylsphingosine | "N,N-dimethylsphingosine results in decreased activity of SPHK1 protein" | 17065523|1928456 |
| C061800 | N,N-dimethylsphingosine | "N,N-dimethylsphingosine results in decreased expression of SPHK1 protein" | 21195056 |
| C061800 | N,N-dimethylsphingosine | "N,N-dimethylsphingosine inhibits the reaction [Glucose results in increased activity of SPHK1 protein]" | 21998146 |
| C025589 | ochratoxin A | ochratoxin A metabolite results in decreased expression of SPHK1 mRNA | 26314263 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of SPHK1 mRNA | 26314263 |
| C053238 | onapristone | onapristone inhibits the reaction [Progesterone results in increased expression of SPHK1 mRNA] | 17164439 |
| C053238 | onapristone | onapristone results in decreased expression of SPHK1 mRNA | 17164439 |
| C510784 | ormosil | [ormosil binds to Polyethylene Glycols] which results in increased expression of SPHK1 mRNA | 24888373 |
| C030110 | oxaliplatin | [oxaliplatin co-treated with Topotecan] results in decreased expression of SPHK1 mRNA | 25729387 |
| C030110 | oxaliplatin | oxaliplatin results in decreased expression of SPHK1 mRNA | 25729387 |
| D010081 | Oxazolone | Oxazolone results in increased activity of SPHK1 protein | 24055189 |
| D010081 | Oxazolone | resveratrol inhibits the reaction [Oxazolone results in increased activity of SPHK1 protein] | 24055189 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SPHK1 mRNA | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of SPHK1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of SPHK1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SPHK1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SPHK1 mRNA] | 17655762 |
| D010126 | Ozone | Ozone results in increased expression of SPHK1 mRNA | 28623178 |
| C496932 | panobinostat | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C496932 | panobinostat | panobinostat results in increased expression of SPHK1 mRNA | 26272509 |
| D052638 | Particulate Matter | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of SPHK1 mRNA] | 17655762 |
| D052638 | Particulate Matter | Particulate Matter affects the expression of SPHK1 mRNA | 17655762 |
| D052638 | Particulate Matter | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SPHK1 mRNA] | 17655762 |
| D052638 | Particulate Matter | fumonisin B1 inhibits the reaction [Particulate Matter results in increased expression of SPHK1 mRNA] | 27376354 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of SPHK1 mRNA | 27376354 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of SPHK1 mRNA | 19159669 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in increased expression of SPHK1 mRNA | 26272509 |
| D010705 | Phosgene | Phosgene affects the expression of SPHK1 mRNA | 16300373 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SPHK1 mRNA | 19710929 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of SPHK1 mRNA | 16985257 |
| D010936 | Plant Extracts | Plant Extracts results in decreased activity of and results in decreased expression of SPHK1 protein | 22251058 |
| D011092 | Polyethylene Glycols | [ormosil binds to Polyethylene Glycols] which results in increased expression of SPHK1 mRNA | 24888373 |
| C060540 | polyhexamethyleneguanidine | polyhexamethyleneguanidine results in increased expression of SPHK1 mRNA | 27989595 |
| D011192 | Potassium Dichromate | Potassium Dichromate results in decreased expression of SPHK1 mRNA | 23608068 |
| D011374 | Progesterone | Mifepristone inhibits the reaction [Progesterone results in increased expression of SPHK1 mRNA] | 17164439 |
| D011374 | Progesterone | onapristone inhibits the reaction [Progesterone results in increased expression of SPHK1 mRNA] | 17164439 |
| D011374 | Progesterone | Progesterone results in increased expression of SPHK1 mRNA | 17164439 |
| D011441 | Propylthiouracil | Propylthiouracil affects the expression of SPHK1 mRNA | 24780913 |
| D011733 | Pyridoxamine | Pyridoxamine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein] | 21998146 |
| D011899 | Ranitidine | Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SPHK1 mRNA] | 16415329 |
| C059514 | resveratrol | resveratrol affects the localization of and results in decreased activity of SPHK1 protein | 26045781 |
| C059514 | resveratrol | [resveratrol affects the localization of and results in decreased activity of SPHK1 protein] which results in decreased abundance of sphingosine 1-phosphate | 26045781 |
| C059514 | resveratrol | [resveratrol affects the localization of and results in decreased activity of SPHK1 protein] which results in increased abundance of Ceramides | 26045781 |
| C059514 | resveratrol | resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] | 19284563|1934629 |
| C059514 | resveratrol | resveratrol metabolite results in decreased activity of SPHK1 protein | 22251058 |
| C059514 | resveratrol | resveratrol metabolite results in decreased expression of SPHK1 protein | 22251058 |
| C059514 | resveratrol | resveratrol results in decreased activity of SPHK1 protein | 22251058 |
| C059514 | resveratrol | [resveratrol results in decreased activity of SPHK1 protein] inhibits the reaction [C5 protein results in increased activity of RELA protein] | 19284563 |
| C059514 | resveratrol | resveratrol results in decreased expression of SPHK1 | 21500096 |
| C059514 | resveratrol | resveratrol results in decreased expression of SPHK1 mRNA | 20401667 |
| C059514 | resveratrol | resveratrol results in decreased expression of SPHK1 protein | 22251058 |
| C059514 | resveratrol | resveratrol results in increased expression of SPHK1 mRNA | 16624241 |
| C059514 | resveratrol | resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] | 19346296 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Oxazolone results in increased activity of SPHK1 protein] | 24055189 |
| C089730 | rosiglitazone | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SPHK1 mRNA | 16054899 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of SPHK1 mRNA | 22300531|2535159 |
| D012906 | Smoke | Smoke affects the expression of SPHK1 mRNA | 23693141 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SPHK1 mRNA | 22714537 |
| D012969 | Sodium Fluoride | Sodium Fluoride results in increased expression of SPHK1 mRNA | 27862939 |
| D012999 | Soman | Soman results in increased expression of SPHK1 mRNA | 19281266 |
| D053260 | Soot | Soot results in increased expression of SPHK1 mRNA | 26551751 |
| C060506 | sphingosine 1-phosphate | [resveratrol affects the localization of and results in decreased activity of SPHK1 protein] which results in decreased abundance of sphingosine 1-phosphate | 26045781 |
| C060506 | sphingosine 1-phosphate | sphingosine 1-phosphate inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SPHK1 mRNA] | 24399507 |
| C060506 | sphingosine 1-phosphate | sphingosine 1-phosphate inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SPHK1 protein] | 24399507 |
| C060506 | sphingosine 1-phosphate | SPHK1 protein results in increased chemical synthesis of sphingosine 1-phosphate | 22251058 |
| C060506 | sphingosine 1-phosphate | [SPHK1 protein results in increased metabolism of Ceramides] which results in increased chemical synthesis of sphingosine 1-phosphate | 21500096 |
| D013311 | Streptozocin | Streptozocin results in increased expression of SPHK1 | 19657322 |
| D013311 | Streptozocin | Streptozocin results in increased expression of SPHK1 mRNA | 21998146 |
| D013311 | Streptozocin | Streptozocin results in increased expression of SPHK1 protein | 21998146 |
| D010042 | Ouabain | Ouabain results in decreased expression of SPHK1 mRNA | 28795476 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of SPHK1 mRNA | 15604281 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SPHK1 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SPHK1 mRNA | 19933214 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SPHK1 mRNA | 16960034|2196442 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SPHK1 mRNA | 25613284 |
| C009495 | titanium dioxide | titanium dioxide results in decreased expression of SPHK1 mRNA | 23557971 |
| C009495 | titanium dioxide | titanium dioxide results in increased expression of SPHK1 mRNA | 27760801 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of SPHK1 mRNA | 28065790 |
| D019772 | Topotecan | [oxaliplatin co-treated with Topotecan] results in decreased expression of SPHK1 mRNA | 25729387 |
| D019772 | Topotecan | Topotecan results in decreased expression of SPHK1 mRNA | 25729387 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of SPHK1 mRNA | 23830798 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of SPHK1 mRNA | 20488242 |
| C011559 | tributyltin | tributyltin results in decreased expression of SPHK1 mRNA | 26314263 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SPHK1 mRNA | 24935251|2627250 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SPHK1 mRNA | 23179753|2438349 |
| D014635 | Valproic Acid | Valproic Acid results in increased methylation of SPHK1 gene | 29154799 |
| C066075 | vanadium pentoxide | vanadium pentoxide affects the expression of SPHK1 mRNA | 26210822 |
| D001335 | Vehicle Emissions | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of SPHK1 mRNA] | 17655762 |
| D001335 | Vehicle Emissions | Vehicle Emissions affects the expression of SPHK1 mRNA | 17655762 |
| D001335 | Vehicle Emissions | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SPHK1 mRNA] | 17655762 |
| D001335 | Vehicle Emissions | fumonisin B1 inhibits the reaction [Vehicle Emissions results in increased expression of SPHK1 mRNA] | 27376354 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased expression of SPHK1 mRNA | 27376354 |
| C025643 | vinclozolin | vinclozolin results in increased expression of SPHK1 mRNA | 22570695 |
| D024483 | Vitamin K 3 | Vitamin K 3 affects the expression of SPHK1 mRNA | 20044591 |
| C111237 | vorinostat | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPHK1 mRNA" | 27188386 |
| C111237 | vorinostat | vorinostat results in increased expression of SPHK1 mRNA | 26272509 |