| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| P4HB | 0.907 |
| SURF4 | 0.9 |
| RNF4 | 0.897 |
| OSER1 | 0.892 |
| USP39 | 0.889 |
| KHSRP | 0.887 |
| POLDIP3 | 0.887 |
| UBAP1 | 0.887 |
| PGD | 0.884 |
| TOP1 | 0.883 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| OR4F5 | -0.707 |
| OR4F29 | -0.669 |
| KLRB1 | -0.265 |
| CETP | -0.245 |
| FCRL1 | -0.244 |
| XCL2 | -0.242 |
| P2RY14 | -0.238 |
| KLRF1 | -0.238 |
| CPA3 | -0.234 |
| CTNNA3 | -0.231 |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C478160 | (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane | "[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of SQSTM1 protein" | 28757135 |
| C012277 | 1,2-diamino-4-nitrobenzene | "1,2-diamino-4-nitrobenzene results in increased expression of SQSTM1 mRNA" | 26198647 |
| C049325 | 1,2-dithiol-3-thione | "1,2-dithiol-3-thione results in increased expression of SQSTM1 mRNA" | 19162173 |
| C576882 | 1-(2-trifluoromethoxyphenyl)-2-nitroethanone | 1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of SQSTM1 mRNA | 25596134 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of SQSTM1 mRNA" | 28903501 |
| C015262 | 1,6-hexamethylene diisocyanate | "1,6-hexamethylene diisocyanate results in increased expression of SQSTM1 mRNA" | 24211530 |
| C029790 | 2,2',3',4,4',5-hexachlorobiphenyl | "2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of SQSTM1 mRNA" | 23829299 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of SQSTM1 mRNA" | 25614096 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of SQSTM1 mRNA" | 25305463 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] | 17360324 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQSTM1 mRNA" | 19167446 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] | 17360324 |
| C000599179 | 28-O-acetylbetulin-3-ylglucopyranoside | 28-O-acetylbetulin-3-ylglucopyranoside results in increased expression of SQSTM1 protein | 22343715 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of SQSTM1 mRNA" | 15215175 |
| C091423 | 2-chloromethylpyridine | 2-chloromethylpyridine results in increased expression of SQSTM1 mRNA | 26198647 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| C018855 | 2-tert-butylhydroquinone | 2-tert-butylhydroquinone results in increased expression of SQSTM1 protein | 23589329 |
| C025946 | 3-methyladenine | 3-methyladenine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| C025946 | 3-methyladenine | 3-methyladenine inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C025946 | 3-methyladenine | 3-methyladenine results in increased expression of SQSTM1 protein | 20574048 |
| C025946 | 3-methyladenine | "3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| C025946 | 3-methyladenine | 3-methyladenine results in increased expression of SQSTM1 protein | 24833599 |
| C025946 | 3-methyladenine | 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] | 28803810 |
| C523934 | 4(4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl)-benzoic acid ethyl ester | "4(4-(5-nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl)-benzoic acid ethyl ester promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein]" | 26409479 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C035207 | 4-amino-2,6-dinitrotoluene | "4-amino-2,6-dinitrotoluene affects the expression of SQSTM1 mRNA" | 21346803 |
| C032538 | 4-cresol | 4-cresol results in increased expression of SQSTM1 protein | 25668154 |
| C032538 | 4-cresol | SQSTM1 mutant form inhibits the reaction [4-cresol results in increased cleavage of CASP8 protein] | 25668154 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA | 19191707 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| C550547 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | "6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein]" | 25943029 |
| C550547 | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide | "6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide results in decreased degradation of SQSTM1 protein" | 25943029 |
| C030735 | 7-aminocephalosporanic acid | 7-aminocephalosporanic acid results in increased expression of SQSTM1 mRNA | 24211530 |
| C553817 | 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one | "7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of SQSTM1 mRNA" | 19936915 |
| C020738 | 9,10-dihydro-9,10-dihydroxybenzo(a)pyrene | "9,10-dihydro-9,10-dihydroxybenzo(a)pyrene results in increased expression of SQSTM1 mRNA" | 26238291 |
| C501332 | ABT-737 | [Celecoxib co-treated with ABT-737] results in decreased expression of SQSTM1 protein | 20104024 |
| D020909 | Acarbose | SQSTM1 affects the susceptibility to Acarbose | 19207582 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of SQSTM1 mRNA | 25064622 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of SQSTM1 protein | 29136249 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of SQSTM1 mRNA | 21420995|2906747 |
| D000082 | Acetaminophen | Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] | 29136249 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of SQSTM1 mRNA | 15606129|1756273 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of SQSTM1 mRNA | 11264010|1254078 |
| D000082 | Acetaminophen | [Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA | 17585979 |
| D000082 | Acetaminophen | "O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of SQSTM1 mRNA]" | 12540782 |
| D000082 | Acetaminophen | PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA] | 17585979 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein] | 28063998 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein] | 27106530 |
| D000111 | Acetylcysteine | "Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]" | 25301941 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [pyrovalerone analog results in decreased expression of SQSTM1 protein] | 28578026 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [decamethrin results in increased expression of SQSTM1 protein] | 26588882 |
| D000111 | Acetylcysteine | Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| D000171 | Acrolein | Acrolein results in increased expression of SQSTM1 mRNA | 24211530 |
| D000067956 | Adenylyl Cyclase Inhibitors | Adenylyl Cyclase Inhibitors inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| D000067956 | Adenylyl Cyclase Inhibitors | Adenylyl Cyclase Inhibitors results in decreased degradation of SQSTM1 protein | 25943029 |
| D000638 | Amiodarone | Amiodarone affects the expression of SQSTM1 mRNA | 25064622 |
| D000638 | Amiodarone | Amiodarone results in increased expression of SQSTM1 mRNA | 19774075 |
| D000643 | Ammonium Chloride | [Ammonium Chloride co-treated with pentabrominated diphenyl ether 100] results in increased expression of SQSTM1 protein | 27234317 |
| D000643 | Ammonium Chloride | Ammonium Chloride results in increased expression of SQSTM1 protein | 21778691 |
| D000643 | Ammonium Chloride | [resveratrol co-treated with Ammonium Chloride] results in increased expression of SQSTM1 protein | 21778691 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SQSTM1 mRNA | 16483693 |
| C018453 | ammonium hexachloroplatinate | ammonium hexachloroplatinate results in increased expression of SQSTM1 mRNA | 24211530 |
| D000841 | Anisomycin | Anisomycin promotes the reaction [Colistin results in increased degradation of SQSTM1 protein] | 28842171 |
| D000924 | Anticholesteremic Agents | Anticholesteremic Agents inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SQSTM1 mRNA] | 28275691 |
| D000968 | Antimycin A | Antimycin A results in increased expression of SQSTM1 mRNA | 19304788 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in increased expression of SQSTM1 mRNA | 24449571 |
| D016718 | Arachidonic Acid | Arachidonic Acid results in increased expression of SQSTM1 mRNA | 16704987 |
| D001151 | Arsenic | Arsenic affects the methylation of SQSTM1 gene | 25304211 |
| D001151 | Arsenic | Arsenic results in increased expression of SQSTM1 protein | 26385919|2741310 |
| D001151 | Arsenic | Arsenic results in increased methylation of SQSTM1 gene | 25325195 |
| D001151 | Arsenic | CAT protein inhibits the reaction [Arsenic results in increased expression of SQSTM1 protein] | 26385919 |
| D001151 | Arsenic | NFE2L2 mutant form inhibits the reaction [Arsenic results in increased expression of SQSTM1 protein] | 26385919 |
| D001151 | Arsenic | SOD1 protein inhibits the reaction [Arsenic results in increased expression of SQSTM1 protein] | 26385919 |
| D001151 | Arsenic | SOD2 protein inhibits the reaction [Arsenic results in increased expression of SQSTM1 protein] | 26385919 |
| D001151 | Arsenic | SQSTM1 mutant form inhibits the reaction [Arsenic results in increased expression of NFE2L2 protein] | 26385919 |
| D001151 | Arsenic | SQSTM1 mutant form promotes the reaction [Arsenic results in decreased expression of BCL2L1 protein] | 26385919 |
| D001151 | Arsenic | SQSTM1 mutant form promotes the reaction [Arsenic results in decreased expression of BCL2 protein] | 26385919 |
| C006632 | arsenic trioxide | arsenic trioxide promotes the reaction [SQSTM1 protein results in increased localization of BCR protein mutant form] | 22898604 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of SQSTM1 mRNA | 27829220 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of SQSTM1 protein | 20200477|2159458 |
| C006632 | arsenic trioxide | SQSTM1 protein promotes the reaction [arsenic trioxide results in increased degradation of BCR protein mutant form] | 22898604 |
| C006632 | arsenic trioxide | SQSTM1 protein results in decreased susceptibility to arsenic trioxide | 20707922 |
| C006632 | arsenic trioxide | [Tretinoin co-treated with arsenic trioxide] results in increased expression of SQSTM1 mRNA | 15894607 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of SQSTM1 protein | 24801902 |
| C015001 | arsenite | [arsenite co-treated with Benzo(a)pyrene] results in increased expression of SQSTM1 mRNA | 15894712 |
| C015001 | arsenite | arsenite results in increased expression of SQSTM1 mRNA | 15894712 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite affects the expression of SQSTM1 mRNA" | 17331233|2575705 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in increased expression of SQSTM1 mRNA" | 18687144 |
| D016589 | Astemizole | Astemizole results in increased expression of SQSTM1 mRNA | 20221588 |
| D001379 | Azathioprine | Azathioprine results in increased expression of SQSTM1 mRNA | 22623647|2619864 |
| C057620 | bafilomycin A | [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein | 26079942 |
| C057620 | bafilomycin A | [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein | 26079942 |
| C057620 | bafilomycin A | bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of SQSTM1 protein] | 27629431 |
| C057620 | bafilomycin A | bafilomycin A inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein]] | 24451142 |
| C057620 | bafilomycin A | bafilomycin A results in increased expression of SQSTM1 protein | 20574048|2762943 |
| C057620 | bafilomycin A | bafilomycin A promotes the reaction [Paraquat results in increased expression of SQSTM1 protein] | 27246695 |
| C057620 | bafilomycin A | bafilomycin A results in increased expression of SQSTM1 protein | 27246695 |
| C057620 | bafilomycin A | bafilomycin A inhibits the reaction [Cadmium results in decreased expression of SQSTM1 protein] | 27658547 |
| C040929 | bafilomycin A1 | bafilomycin A1 inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 24145604|2594302 |
| C040929 | bafilomycin A1 | bafilomycin A1 results in increased expression of SQSTM1 protein | 21778691|2414560 |
| C040929 | bafilomycin A1 | Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 25939952 |
| C040929 | bafilomycin A1 | [resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein | 21778691 |
| C040929 | bafilomycin A1 | sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 28125038 |
| C040929 | bafilomycin A1 | [TNF protein co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein | 24145604 |
| C040929 | bafilomycin A1 | [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein | 26031332 |
| C040929 | bafilomycin A1 | bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]] | 24889822 |
| C040929 | bafilomycin A1 | bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24238063 |
| C040929 | bafilomycin A1 | bafilomycin A1 results in increased expression of SQSTM1 protein | 24889822|2603133 |
| C040929 | bafilomycin A1 | Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 24889822 |
| C040929 | bafilomycin A1 | [bafilomycin A1 co-treated with bisphenol A co-treated with Sirolimus] results in increased expression of SQSTM1 protein | 26139607 |
| C040929 | bafilomycin A1 | bafilomycin A1 inhibits the reaction [bisphenol A results in decreased expression of SQSTM1 protein] | 26139607 |
| C040929 | bafilomycin A1 | bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| C029876 | benzidine | benzidine results in increased expression of SQSTM1 mRNA | 26198647 |
| C041512 | benzo(b)fluorene | [Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in increased expression of SQSTM1 mRNA | 22120849 |
| D053119 | Benzophenanthridines | [Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in increased expression of SQSTM1 mRNA | 22120849 |
| D053119 | Benzophenanthridines | Benzophenanthridines analog results in increased expression of SQSTM1 mRNA | 22120849 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SQSTM1 mRNA | 26001963 |
| D001564 | Benzo(a)pyrene | [Benzo(a)pyrene co-treated with sodium bichromate] results in increased expression of SQSTM1 mRNA | 21632023 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SQSTM1 mRNA | 20106945|2163298 |
| D001564 | Benzo(a)pyrene | AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of SQSTM1 mRNA] | 15034205 |
| D001564 | Benzo(a)pyrene | [arsenite co-treated with Benzo(a)pyrene] results in increased expression of SQSTM1 mRNA | 15894712 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SQSTM1 mRNA | 15034205|1589471 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] | 27629431 |
| C072553 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] | 27629431 |
| D004958 | Estradiol | Estradiol results in decreased expression of SQSTM1 mRNA | 16474171 |
| D004958 | Estradiol | Estradiol results in increased expression of SQSTM1 mRNA | 20106945 |
| C009479 | beta-thujaplicin | beta-thujaplicin results in decreased expression of SQSTM1 protein | 25044443 |
| C095105 | bexarotene | bexarotene results in increased expression of SQSTM1 mRNA | 16648578 |
| C053541 | bicalutamide | bicalutamide results in increased expression of SQSTM1 mRNA | 15638997 |
| D001688 | Biological Products | Biological Products affects the expression of SQSTM1 protein | 28219700 |
| C543008 | bis(4-hydroxyphenyl)sulfone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA | 28628672 |
| C002791 | bismuth tripotassium dicitrate | bismuth tripotassium dicitrate results in increased expression of SQSTM1 mRNA | 15912405 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of SQSTM1 mRNA | 16474171 |
| C006780 | bisphenol A | bisphenol A results in increased expression of SQSTM1 mRNA | 29275510 |
| C006780 | bisphenol A | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA | 28628672 |
| C006780 | bisphenol A | bisphenol A results in increased expression of SQSTM1 mRNA | 12233820 |
| C006780 | bisphenol A | [bafilomycin A1 co-treated with bisphenol A co-treated with Sirolimus] results in increased expression of SQSTM1 protein | 26139607 |
| C006780 | bisphenol A | bafilomycin A1 inhibits the reaction [bisphenol A results in decreased expression of SQSTM1 protein] | 26139607 |
| C006780 | bisphenol A | bisphenol A affects the expression of SQSTM1 mRNA | 25181051 |
| C006780 | bisphenol A | bisphenol A affects the expression of SQSTM1 protein | 26139607 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of SQSTM1 mRNA | 26139607 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of SQSTM1 gene | 28505145 |
| C006780 | bisphenol A | Sirolimus promotes the reaction [bisphenol A results in decreased expression of SQSTM1 protein] | 26139607 |
| D001786 | Blood Glucose | [Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein | 28477916 |
| D001786 | Blood Glucose | genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein] | 28477916 |
| C557045 | BO-1051 | BO-1051 results in decreased expression of SQSTM1 protein | 21184746 |
| D000069286 | Bortezomib | Bortezomib results in increased expression of SQSTM1 mRNA | 20977926 |
| D000069286 | Bortezomib | Bortezomib results in increased expression of SQSTM1 mRNA | 20830808 |
| C044362 | brazilin | Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein] | 28063998 |
| C044362 | brazilin | brazilin results in decreased expression of SQSTM1 protein | 28063998 |
| C044362 | brazilin | RELA protein promotes the reaction [brazilin results in decreased expression of SQSTM1 protein] | 28063998 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of SQSTM1 mRNA | 23410634 |
| C584509 | C646 compound | C646 compound results in increased expression of SQSTM1 mRNA | 26191083 |
| D002104 | Cadmium | Cadmium results in increased expression of SQSTM1 mRNA | 21120746 |
| D002104 | Cadmium | Cadmium results in increased expression of SQSTM1 mRNA | 24067728 |
| D002104 | Cadmium | [Cadmium co-treated with Copper co-treated with Mercury] results in increased expression of SQSTM1 mRNA | 23355883 |
| D002104 | Cadmium | ATG5 protein affects the reaction [Cadmium results in decreased expression of SQSTM1 protein] | 27658547 |
| D002104 | Cadmium | bafilomycin A inhibits the reaction [Cadmium results in decreased expression of SQSTM1 protein] | 27658547 |
| D002104 | Cadmium | Cadmium results in decreased expression of SQSTM1 protein | 27658547 |
| D002104 | Cadmium | Chloroquine inhibits the reaction [Cadmium results in decreased expression of SQSTM1 protein] | 27658547 |
| C028031 | cadmium acetate | cadmium acetate results in increased expression of SQSTM1 protein | 28347754 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of SQSTM1 mRNA | 17961207 |
| D019256 | Cadmium Chloride | Cadmium Chloride inhibits the reaction [NFE2L2 protein binds to SQSTM1 promoter] | 25157103 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of SQSTM1 mRNA | 25596134 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of SQSTM1 protein | 25157103 |
| D019256 | Cadmium Chloride | NFE2L2 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of SQSTM1 protein] | 25157103 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of SQSTM1 mRNA | 11958953|1550161 |
| D019256 | Cadmium Chloride | MT1 affects the reaction [Cadmium Chloride results in increased expression of SQSTM1 mRNA] | 11958953 |
| D019256 | Cadmium Chloride | MT2 affects the reaction [Cadmium Chloride results in increased expression of SQSTM1 mRNA] | 11958953 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of SQSTM1 protein | 29218509 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of SQSTM1 mRNA | 22110744 |
| D002110 | Caffeine | Caffeine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D002110 | Caffeine | Caffeine results in decreased expression of SQSTM1 protein | 21081844 |
| D002110 | Caffeine | Caffeine results in increased expression of SQSTM1 mRNA | 20864626 |
| D002118 | Calcium | Calcium affects the expression of SQSTM1 mRNA | 15913539 |
| D002166 | Camptothecin | ATG5 mutant form inhibits the reaction [Camptothecin results in increased degradation of SQSTM1 protein] | 22927544 |
| D002166 | Camptothecin | Camptothecin results in increased degradation of SQSTM1 protein | 22927544 |
| C459604 | candoxin | candoxin results in increased expression of SQSTM1 mRNA | 16309724 |
| D002185 | Cannabidiol | Cannabidiol results in increased expression of SQSTM1 mRNA | 21542829 |
| C005563 | captax | captax results in increased expression of SQSTM1 mRNA | 24211530 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of SQSTM1 mRNA | 25979313 |
| D002246 | Carbon Disulfide | Carbon Disulfide results in increased expression of and results in increased phosphorylation of SQSTM1 protein | 27530093 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SQSTM1 mRNA | 27339419 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of SQSTM1 protein | 26882442 |
| D002251 | Carbon Tetrachloride | Melatonin inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein] | 26882442 |
| D000068579 | Celecoxib | [Celecoxib co-treated with ABT-737] results in decreased expression of SQSTM1 protein | 20104024 |
| C026690 | cerous chloride | cerous chloride affects the expression of SQSTM1 mRNA | 28954213 |
| C026690 | cerous chloride | [cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA | 28954213 |
| D002635 | Chenodeoxycholic Acid | Chenodeoxycholic Acid results in increased expression of SQSTM1 protein | 24189133 |
| C004656 | chloroacetaldehyde | chloroacetaldehyde results in increased expression of SQSTM1 mRNA | 25596134 |
| D002726 | Chlorogenic Acid | Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] | 29136249 |
| D020245 | p-Chloromercuribenzoic Acid | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| D020245 | p-Chloromercuribenzoic Acid | p-Chloromercuribenzoic Acid results in increased expression of SQSTM1 mRNA | 26272509 |
| C100187 | chloropicrin | chloropicrin affects the expression of SQSTM1 mRNA | 26352163 |
| C100187 | chloropicrin | chloropicrin results in increased expression of SQSTM1 mRNA | 24211530|2847649 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [cryptotanshinone results in decreased expression of SQSTM1 protein] | 28600121 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein] | 23651616 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [formosanin C results in decreased expression of SQSTM1 protein] | 27180204 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| D002738 | Chloroquine | Chloroquine results in increased expression of SQSTM1 protein | 27588471|2827569 |
| D002738 | Chloroquine | ERGIC3 protein promotes the reaction [Chloroquine results in increased expression of SQSTM1 protein] | 27588471 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [sunitinib results in decreased expression of SQSTM1 protein] | 24751611 |
| D002738 | Chloroquine | Chloroquine inhibits the reaction [Cadmium results in decreased expression of SQSTM1 protein] | 27658547 |
| D002738 | Chloroquine | Chloroquine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| D002746 | Chlorpromazine | Chlorpromazine affects the expression of SQSTM1 mRNA | 25064622 |
| D002784 | Cholesterol | Cholesterol results in increased expression of SQSTM1 protein | 28275691 |
| D002788 | Cholesterol Esters | SAN 58035 promotes the reaction [Cholesterol Esters results in increased expression of SQSTM1 protein] | 28275691 |
| D019826 | Cholic Acid | Cholic Acid results in increased expression of SQSTM1 protein | 24189133 |
| C039671 | ciglitazone | [ciglitazone binds to PPARG protein] which results in increased expression of SQSTM1 mRNA | 16197558 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde results in increased expression of SQSTM1 mRNA | 24211530 |
| C019304 | ciprofibrate | ciprofibrate results in increased expression of SQSTM1 mRNA | 12771043 |
| D002994 | Clofibrate | [Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA | 17585979 |
| D002994 | Clofibrate | PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SQSTM1 mRNA] | 17585979 |
| D003035 | Cobalt | [tungsten carbide co-treated with Cobalt] results in increased expression of SQSTM1 mRNA | 18078969 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of SQSTM1 mRNA | 19320972|1937684 |
| C018021 | cobaltous chloride | cobaltous chloride results in increased expression of SQSTM1 mRNA | 24386269 |
| D005576 | Colforsin | Colforsin results in increased degradation of SQSTM1 protein | 25943029 |
| D003091 | Colistin | Anisomycin promotes the reaction [Colistin results in increased degradation of SQSTM1 protein] | 28842171 |
| D003091 | Colistin | Colistin results in increased degradation of SQSTM1 protein | 28842171 |
| D003091 | Colistin | pyrazolanthrone inhibits the reaction [Colistin results in increased degradation of SQSTM1 protein] | 28842171 |
| D003300 | Copper | [Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein | 25301941 |
| D003300 | Copper | [NSC 689534 binds to Copper] which results in increased expression of SQSTM1 mRNA | 20971185 |
| D003300 | Copper | [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNA | 25167922 |
| D003300 | Copper | [Cadmium co-treated with Copper co-treated with Mercury] results in increased expression of SQSTM1 mRNA | 23355883 |
| D019327 | Copper Sulfate | Copper Sulfate results in increased expression of SQSTM1 mRNA | 19549813 |
| D019327 | Copper Sulfate | Copper Sulfate results in increased expression of SQSTM1 mRNA | 19070373 |
| C423222 | cotylenin A | [cotylenin A co-treated with Vincristine] results in increased degradation of SQSTM1 protein | 25672400 |
| D003375 | Coumestrol | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQSTM1 mRNA" | 19167446 |
| D003375 | Coumestrol | Coumestrol results in decreased expression of SQSTM1 mRNA | 19167446 |
| C037886 | cryptotanshinone | Chloroquine inhibits the reaction [cryptotanshinone results in decreased expression of SQSTM1 protein] | 28600121 |
| C037886 | cryptotanshinone | cryptotanshinone results in decreased expression of SQSTM1 protein | 28600121 |
| C102326 | cucurbitacin E | Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein] | 27106530 |
| C102326 | cucurbitacin E | cucurbitacin E results in increased expression of SQSTM1 protein | 27106530 |
| C029892 | cupric chloride | cupric chloride results in increased expression of SQSTM1 mRNA | 17211630 |
| C029892 | cupric chloride | cupric chloride results in increased expression of SQSTM1 protein | 23313662 |
| D016572 | Cyclosporine | Cyclosporine affects the expression of SQSTM1 mRNA | 25064622 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of SQSTM1 mRNA | 20106945|2556210 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of SQSTM1 mRNA | 19770486 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of SQSTM1 mRNA | 25596134 |
| C017160 | cypermethrin | cypermethrin results in increased expression of SQSTM1 mRNA | 27704156 |
| D003609 | Dactinomycin | "Dactinomycin inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA]" | 25301941 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein] | 24095927 |
| C531198 | dactolisib | Chloroquine inhibits the reaction [dactolisib results in decreased expression of SQSTM1 protein] | 23651616 |
| C531198 | dactolisib | dactolisib results in decreased expression of SQSTM1 protein | 23651616 |
| D003634 | DDT | DDT results in increased expression of SQSTM1 mRNA | 26198647 |
| C017180 | decamethrin | Acetylcysteine inhibits the reaction [decamethrin results in increased expression of SQSTM1 protein] | 26588882 |
| C017180 | decamethrin | decamethrin results in increased expression of SQSTM1 protein | 26588882 |
| C014347 | decitabine | decitabine affects the expression of SQSTM1 mRNA | 23300844 |
| D003671 | DEET | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA | 28659758 |
| D003676 | Deferoxamine | [Copper co-treated with Deferoxamine] results in increased expression of SQSTM1 protein | 25301941 |
| D003676 | Deferoxamine | Deferoxamine results in increased expression of SQSTM1 protein | 25301941 |
| D003676 | Deferoxamine | [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein | 25301941 |
| D013759 | Dronabinol | Dronabinol results in increased expression of SQSTM1 mRNA | 16597638 |
| D013759 | Dronabinol | Dronabinol results in increased expression of SQSTM1 mRNA | 21542829 |
| C576677 | demycarosyl-3D-digitoxosylmithramycin SK | [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein | 26079942 |
| C576677 | demycarosyl-3D-digitoxosylmithramycin SK | demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA | 26079942 |
| C576677 | demycarosyl-3D-digitoxosylmithramycin SK | Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] | 26079942 |
| C576677 | demycarosyl-3D-digitoxosylmithramycin SK | Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] | 26079942 |
| D003847 | Deoxyglucose | [bafilomycin A co-treated with Deoxyglucose] affects the expression of SQSTM1 protein | 26079942 |
| D003847 | Deoxyglucose | [bafilomycin A co-treated with Deoxyglucose co-treated with demycarosyl-3D-digitoxosylmithramycin SK] affects the expression of SQSTM1 protein | 26079942 |
| D003847 | Deoxyglucose | Deoxyglucose inhibits the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] | 26079942 |
| D003847 | Deoxyglucose | Deoxyglucose promotes the reaction [demycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of SQSTM1 mRNA] | 26079942 |
| D003907 | Dexamethasone | Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SQSTM1 mRNA] | 27941970 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA | 28628672 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA | 28628672 |
| C539263 | di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone | "Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]" | 25301941 |
| C539263 | di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone | "Dactinomycin inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA]" | 25301941 |
| C539263 | di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone | "di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA" | 25301941 |
| C539263 | di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone | "di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein" | 25301941 |
| C539263 | di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone | "Iron affects the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]" | 25301941 |
| D003976 | Diazinon | Diazinon results in increased expression of SQSTM1 mRNA | 26198647 |
| D003976 | Diazinon | Diazinon results in increased methylation of SQSTM1 gene | 22964155 |
| D003976 | Diazinon | Diazinon affects the expression of SQSTM1 mRNA | 22546817 |
| C023614 | dibenzofuran | dibenzofuran results in decreased expression of SQSTM1 protein | 22173198 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of SQSTM1 protein | 26804720 |
| D002945 | Cisplatin | Cisplatin affects the expression of SQSTM1 mRNA | 23300844 |
| D002945 | Cisplatin | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of SQSTM1 mRNA] | 21858171 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of SQSTM1 protein | 26201060 |
| D002945 | Cisplatin | Cisplatin results in increased expression of SQSTM1 mRNA | 27594783 |
| D002945 | Cisplatin | Cisplatin results in increased expression of SQSTM1 protein | 21184746 |
| D002945 | Cisplatin | SQSTM1 protein results in decreased susceptibility to Cisplatin | 21371883 |
| D004026 | Dieldrin | Dieldrin affects the expression of SQSTM1 mRNA | 22546817 |
| D004041 | Dietary Fats | Anticholesteremic Agents inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SQSTM1 mRNA] | 28275691 |
| D004041 | Dietary Fats | [Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SQSTM1 mRNA | 28275691 |
| D004041 | Dietary Fats | [Dietary Fats co-treated with Dietary Sucrose] results in increased expression of SQSTM1 protein | 28275691 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of SQSTM1 protein | 26655953 |
| D004041 | Dietary Fats | obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of SQSTM1 protein] | 26655953 |
| D019422 | Dietary Sucrose | Anticholesteremic Agents inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SQSTM1 mRNA] | 28275691 |
| D019422 | Dietary Sucrose | [Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SQSTM1 mRNA | 28275691 |
| D019422 | Dietary Sucrose | [Dietary Fats co-treated with Dietary Sucrose] results in increased expression of SQSTM1 protein | 28275691 |
| C014476 | diethyl maleate | diethyl maleate results in increased expression of SQSTM1 mRNA | 25270620 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of SQSTM1 mRNA | 12771043 |
| C472036 | dihydromyricetin | dihydromyricetin promotes the reaction [Ethanol results in increased expression of SQSTM1 protein] | 28419832 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | "9,10-Dimethyl-1,2-benzanthracene results in decreased expression of SQSTM1 mRNA" | 22485181 |
| D004237 | Diuron | Diuron results in increased expression of SQSTM1 mRNA | 21551480 |
| D004317 | Doxorubicin | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | 3-methyladenine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | Acetylcysteine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | ATG7 mutant form inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | Caffeine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | Chloroquine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | Doxorubicin results in increased degradation of SQSTM1 protein | 22927544 |
| D004317 | Doxorubicin | Doxorubicin results in increased expression of SQSTM1 protein | 21184746 |
| D004317 | Doxorubicin | Glutathione inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| D004317 | Doxorubicin | Doxorubicin results in increased expression of SQSTM1 mRNA | 16243910|2589636 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of SQSTM1 protein | 27666003 |
| D004317 | Doxorubicin | Doxorubicin results in increased expression of SQSTM1 mRNA | 19915844 |
| C108024 | emamectin benzoate | emamectin benzoate results in increased expression of SQSTM1 mRNA | 18786259 |
| D004811 | Epichlorohydrin | Epichlorohydrin results in increased expression of SQSTM1 mRNA | 24211530 |
| C045651 | epigallocatechin gallate | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SQSTM1 mRNA | 22079256 |
| D004967 | Estrogens | Estrogens promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein] | 26631322 |
| D004967 | Estrogens | SOCS3 mutant form inhibits the reaction [Estrogens promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]] | 26631322 |
| D000431 | Ethanol | ADIPOQ protein inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein] | 24582693 |
| D000431 | Ethanol | ATG5 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] | 24582693 |
| D000431 | Ethanol | Ethanol results in increased expression of SQSTM1 protein | 24582693 |
| D000431 | Ethanol | Dactinomycin inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein] | 24095927 |
| D000431 | Ethanol | dihydromyricetin promotes the reaction [Ethanol results in increased expression of SQSTM1 protein] | 28419832 |
| D000431 | Ethanol | Ethanol results in decreased expression of SQSTM1 protein | 22459179|2409592 |
| D000431 | Ethanol | Ethanol results in increased degradation of SQSTM1 protein | 24492484 |
| D000431 | Ethanol | Ethanol results in increased expression of SQSTM1 mRNA | 25460735 |
| D000431 | Ethanol | Ethanol results in increased expression of SQSTM1 protein | 25460735|2841983 |
| D000431 | Ethanol | NR1H4 gene mutant form promotes the reaction [Ethanol results in increased expression of SQSTM1 protein] | 25460735 |
| D000431 | Ethanol | [wortmannin co-treated with Ethanol] results in increased expression of SQSTM1 protein | 22459179 |
| D000431 | Ethanol | Ethanol results in decreased expression of SQSTM1 mRNA | 16098508 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of SQSTM1 mRNA | 25064622 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of SQSTM1 mRNA | 17555576 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of SQSTM1 mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQSTM1 mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of SQSTM1 mRNA | 17108234 |
| D005035 | Ethylmercury Compounds | Ethylmercury Compounds results in increased expression of SQSTM1 protein | 27511942 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased expression of SQSTM1 mRNA | 23649840 |
| D005054 | Eugenol | Eugenol results in increased expression of SQSTM1 mRNA | 26198647 |
| D018690 | Excitatory Amino Acid Agonists | Excitatory Amino Acid Agonists results in increased degradation of SQSTM1 protein | 24675465 |
| D011345 | Fenofibrate | Fenofibrate results in increased expression of SQSTM1 mRNA | 25596134 |
| D000068876 | Fingolimod Hydrochloride | Fingolimod Hydrochloride affects the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 25939952 |
| D000068876 | Fingolimod Hydrochloride | Fingolimod Hydrochloride results in decreased expression of SQSTM1 protein | 25939952 |
| D000068876 | Fingolimod Hydrochloride | SQSTM1 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of CASP8 protein] | 25939952 |
| D000068876 | Fingolimod Hydrochloride | SQSTM1 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein] | 25939952 |
| D005473 | Fluoxetine | Fluoxetine results in decreased expression of SQSTM1 mRNA | 17105902 |
| D005485 | Flutamide | Flutamide results in increased expression of SQSTM1 mRNA | 24136188 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of SQSTM1 mRNA | 20655997|2364984 |
| C067584 | formosanin C | Chloroquine inhibits the reaction [formosanin C results in decreased expression of SQSTM1 protein] | 27180204 |
| C067584 | formosanin C | formosanin C results in decreased expression of SQSTM1 protein | 27180204 |
| C058728 | fosbretabulin | fosbretabulin results in increased degradation of SQSTM1 protein | 24321340 |
| C056933 | fumonisin B1 | fumonisin B1 results in increased expression of SQSTM1 mRNA | 16221962 |
| D008299 | Maleic Anhydrides | Maleic Anhydrides results in increased expression of SQSTM1 mRNA | 24211530 |
| C000600490 | G226 compound | G226 compound results in increased expression of SQSTM1 protein | 25066322 |
| C419708 | gefitinib | EGFR gene mutant form promotes the reaction [gefitinib results in decreased expression of SQSTM1 protein] | 27639429 |
| C419708 | gefitinib | gefitinib results in decreased expression of SQSTM1 protein | 27639429 |
| C007834 | genipin | genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein] | 28477916 |
| D019833 | Genistein | Genistein results in decreased expression of SQSTM1 mRNA | 16474171 |
| D005947 | Glucose | "3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| D005947 | Glucose | Glucose results in increased expression of SQSTM1 protein | 29128638 |
| D005947 | Glucose | "N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]" | 29128638 |
| D005947 | Glucose | "Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| D005947 | Glucose | ULK1 protein affects the reaction [Glucose results in increased expression of SQSTM1 protein] | 29128638 |
| D005947 | Glucose | "ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| D005978 | Glutathione | Glutathione inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein] | 22927544 |
| C071834 | glycidamide | glycidamide results in increased expression of SQSTM1 mRNA | 17822822 |
| C010974 | glyphosate | glyphosate results in increased expression of SQSTM1 mRNA | 25636363 |
| C059922 | gossypetin | "gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SQSTM1 protein]" | 25622137 |
| D006108 | Graphite | Graphite metabolite results in increased expression of SQSTM1 protein | 27845169 |
| C412815 | GW 4064 | GW 4064 results in increased expression of SQSTM1 mRNA | 22952826 |
| C412815 | GW 4064 | GW 4064 results in increased expression of SQSTM1 protein | 22952826 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of SQSTM1 mRNA | 26846883 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide affects the expression of SQSTM1 mRNA | 23410634 |
| D006861 | Hydrogen Peroxide | SQSTM1 protein results in decreased susceptibility to Hydrogen Peroxide | 17360324 |
| D006861 | Hydrogen Peroxide | bafilomycin A1 promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of SQSTM1 protein | 24889822 |
| D006861 | Hydrogen Peroxide | RAB7A protein inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| D006861 | Hydrogen Peroxide | RAB7A protein promotes the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| D006861 | Hydrogen Peroxide | resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| D006861 | Hydrogen Peroxide | SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| D006861 | Hydrogen Peroxide | sirtinol inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| D006861 | Hydrogen Peroxide | sirtinol promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| C031927 | hydroquinone | hydroquinone results in decreased expression of SQSTM1 protein | 28263894 |
| D006997 | Hypochlorous Acid | Hypochlorous Acid results in increased expression of SQSTM1 mRNA | 19376150 |
| C492448 | ICG 001 | ICG 001 results in increased expression of SQSTM1 mRNA | 26191083 |
| C531470 | icotinib | EGFR gene mutant form promotes the reaction [icotinib results in decreased expression of SQSTM1 protein] | 27639429 |
| C531470 | icotinib | icotinib results in decreased expression of SQSTM1 protein | 27639429 |
| D007069 | Ifosfamide | Ifosfamide results in increased expression of SQSTM1 mRNA | 25596134 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in increased expression of SQSTM1 protein | 22641616 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA | 28628672 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA | 28628672 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of SQSTM1 mRNA | 25613284 |
| D007501 | Iron | "Iron affects the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]" | 25301941 |
| D007501 | Iron | [Iron co-treated with Deferoxamine] results in increased expression of SQSTM1 protein | 25301941 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of SQSTM1 mRNA | 28628672 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SQSTM1 mRNA | 28628672 |
| D007529 | Isoflavones | Isoflavones affects the expression of SQSTM1 mRNA | 16365062 |
| D007529 | Isoflavones | Isoflavones results in increased expression of SQSTM1 mRNA | 17374662 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of SQSTM1 mRNA | 20003209 |
| C544151 | jinfukang | jinfukang results in increased expression of SQSTM1 mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in increased expression of SQSTM1 mRNA | 21889194 |
| C410337 | K 7174 | K 7174 results in increased expression of SQSTM1 mRNA | 24086573 |
| C028521 | lanthanum chloride | [cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA | 28954213 |
| D007854 | Lead | Lead affects the expression of SQSTM1 mRNA | 28903495 |
| D007854 | Lead | Lead affects the splicing of SQSTM1 mRNA | 28903495 |
| C017461 | lead nitrate | lead nitrate affects the reaction [SQSTM1 affects the expression of MT1 mRNA] | 11891201 |
| C017461 | lead nitrate | lead nitrate affects the reaction [SQSTM1 affects the expression of MT2 mRNA] | 11891201 |
| C017461 | lead nitrate | lead nitrate results in increased expression of SQSTM1 protein | 27762461 |
| C017461 | lead nitrate | puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein] | 27762461 |
| C045463 | leflunomide | leflunomide results in increased expression of SQSTM1 mRNA | 28988120 |
| C045463 | leflunomide | leflunomide results in increased expression of SQSTM1 mRNA | 24136188 |
| D001556 | Lindane | Lindane results in increased expression of SQSTM1 mRNA | 26198647 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of SQSTM1 mRNA | 19070373 |
| D058185 | Magnetite Nanoparticles | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SQSTM1 mRNA | 21641980 |
| D058185 | Magnetite Nanoparticles | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SQSTM1 mRNA | 26378955 |
| D008298 | Maleates | Maleates results in decreased expression of SQSTM1 protein | 21976531 |
| C569869 | malondialdehyde-low density lipoprotein, human | "gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of SQSTM1 protein]" | 25622137 |
| C569869 | malondialdehyde-low density lipoprotein, human | "malondialdehyde-low density lipoprotein, human results in increased expression of SQSTM1 protein" | 25622137 |
| C025340 | manganese chloride | [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with manganese chloride] results in decreased expression of SQSTM1 protein | 28856835 |
| C025340 | manganese chloride | Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| C025340 | manganese chloride | Chloroquine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| C025340 | manganese chloride | manganese chloride results in increased expression of SQSTM1 protein | 29222055 |
| C025340 | manganese chloride | resveratrol promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| C025340 | manganese chloride | Sirolimus inhibits the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| D008550 | Melatonin | Melatonin inhibits the reaction [Carbon Tetrachloride results in increased expression of SQSTM1 protein] | 26882442 |
| C042720 | mercuric bromide | mercuric bromide results in increased expression of SQSTM1 mRNA | 26272509 |
| C042720 | mercuric bromide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| D008627 | Mercuric Chloride | Mercuric Chloride affects the expression of SQSTM1 mRNA | 20353558 |
| D008628 | Mercury | [Cadmium co-treated with Copper co-treated with Mercury] results in increased expression of SQSTM1 mRNA | 23355883 |
| D008687 | Metformin | Metformin results in increased expression of SQSTM1 mRNA | 25596134 |
| D008694 | Methamphetamine | Methamphetamine results in increased expression of SQSTM1 protein | 23933405 |
| D008727 | Methotrexate | Methotrexate results in increased expression of SQSTM1 mRNA | 21678067 |
| C013598 | methoxyacetic acid | methoxyacetic acid results in increased expression of SQSTM1 mRNA | 20864626|9681501 |
| C005219 | methyl cellosolve | methyl cellosolve results in increased expression of SQSTM1 mRNA | 9681501 |
| D008753 | Methylenebis(chloroaniline) | Methylenebis(chloroaniline) results in increased expression of SQSTM1 mRNA | 26198647 |
| C002950 | methylformamide | methylformamide affects the expression of SQSTM1 mRNA | 17040096 |
| C002950 | methylformamide | methylformamide analog affects the expression of SQSTM1 mRNA | 17040096 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SQSTM1 mRNA | 17961207|2018165 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SQSTM1 mRNA | 28001369 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SQSTM1 protein | 27667695 |
| C004925 | methylmercuric chloride | ATG5 promotes the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | 27667695 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SQSTM1 protein | 27667695 |
| C004925 | methylmercuric chloride | pyrazolanthrone inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | 27667695 |
| C004925 | methylmercuric chloride | U 0126 inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | 27667695 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SQSTM1 mRNA | 20864626 |
| D008767 | Methylmercury Compounds | Methylmercury Compounds results in decreased expression of SQSTM1 protein | 26558463 |
| C030957 | methylmercury II | methylmercury II results in increased expression of SQSTM1 mRNA | 17905399 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of SQSTM1 mRNA | 26011545 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in decreased expression of SQSTM1 mRNA | 23649840 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of SQSTM1 mRNA | 23649840 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein] | 26409479 |
| C028577 | monobutyl phthalate | monobutyl phthalate results in increased expression of SQSTM1 mRNA | 20864626 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in decreased expression of SQSTM1 mRNA | 22108045 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in increased expression of SQSTM1 protein | 24625837 |
| D009151 | Mustard Gas | Mustard Gas results in increased phosphorylation of SQSTM1 protein | 19845377 |
| C531525 | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | "3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| C531525 | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | "N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]" | 29128638 |
| C531525 | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | "Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| C531525 | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | "ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| C496401 | N-((3-(aminomethyl)phenyl)methyl)ethanimidamide | [N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with manganese chloride] results in decreased expression of SQSTM1 protein | 28856835 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of SQSTM1 protein" | 24389112 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of SQSTM1 mRNA" | 25554681 |
| C017096 | n-butoxyethanol | n-butoxyethanol results in increased expression of SQSTM1 mRNA | 19812364 |
| C051752 | nefazodone | nefazodone results in increased expression of SQSTM1 mRNA | 24136188 |
| D009532 | Nickel | Nickel results in decreased expression of SQSTM1 mRNA | 24084258 |
| C022838 | nickel chloride | nickel chloride affects the expression of SQSTM1 mRNA | 22546817 |
| C022838 | nickel chloride | nickel chloride results in increased expression of SQSTM1 mRNA | 22110744 |
| C028007 | nickel monoxide | nickel monoxide results in increased expression of SQSTM1 mRNA | 19167457 |
| D009534 | Niclosamide | Niclosamide results in increased expression of SQSTM1 mRNA | 26452273 |
| C012655 | nimesulide | nimesulide results in increased expression of SQSTM1 mRNA | 24136188 |
| D009584 | Nitrogen | bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of SQSTM1 protein] | 27629431 |
| D009584 | Nitrogen | Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] | 27629431 |
| D009584 | Nitrogen | Nitrogen deficiency results in decreased expression of SQSTM1 protein | 27629431 |
| C010615 | Nonidet P-40 | Nonidet P-40 results in decreased expression of SQSTM1 mRNA | 26552463 |
| C558013 | NSC 689534 | [NSC 689534 binds to Copper] which results in increased expression of SQSTM1 mRNA | 20971185 |
| C107010 | O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate | "O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of SQSTM1 mRNA]" | 12540782 |
| C464660 | obeticholic acid | obeticholic acid inhibits the reaction [Dietary Fats results in decreased expression of SQSTM1 protein] | 26655953 |
| D016627 | Oxidopamine | Oxidopamine promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein] | 26409479 |
| D016627 | Oxidopamine | Oxidopamine results in decreased expression of SQSTM1 protein | 28802652 |
| C507134 | ON 01910 | ON 01910 affects the expression of SQSTM1 mRNA | 22351695 |
| D016566 | Organoselenium Compounds | [Organoselenium Compounds binds to Copper] which results in increased expression of SQSTM1 mRNA | 25167922 |
| C030110 | oxaliplatin | [oxaliplatin co-treated with Topotecan] results in increased expression of SQSTM1 mRNA | 25729387 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SQSTM1 mRNA | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of SQSTM1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of SQSTM1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SQSTM1 mRNA] | 17655762 |
| C472349 | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SQSTM1 mRNA] | 17655762 |
| D010100 | Oxygen | Oxygen deficiency results in decreased expression of SQSTM1 mRNA | 25596134 |
| D010100 | Oxygen | [Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein | 28477916 |
| D010100 | Oxygen | genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SQSTM1 protein] | 28477916 |
| D010269 | Paraquat | Paraquat affects the expression of SQSTM1 mRNA | 25064622 |
| D010269 | Paraquat | [Paraquat co-treated with MAP3K5 protein] results in increased degradation of SQSTM1 protein | 20929985 |
| D010269 | Paraquat | Paraquat promotes the reaction [SQSTM1 protein binds to and results in decreased activity of SQSTM1 protein] | 26409479 |
| D010269 | Paraquat | Paraquat results in increased degradation of SQSTM1 protein | 20929985 |
| D010269 | Paraquat | salubrinal promotes the reaction [[Paraquat co-treated with MAP3K5 protein] results in increased degradation of SQSTM1 protein] | 20929985 |
| D010269 | Paraquat | bafilomycin A promotes the reaction [Paraquat results in increased expression of SQSTM1 protein] | 27246695 |
| D010269 | Paraquat | Paraquat results in decreased expression of SQSTM1 protein | 25092649 |
| D010269 | Paraquat | Paraquat results in increased expression of SQSTM1 mRNA | 12595580 |
| D010269 | Paraquat | Paraquat results in increased expression of SQSTM1 protein | 27246695 |
| D010269 | Paraquat | TLR4 protein affects the reaction [Paraquat results in increased expression of SQSTM1 protein] | 27246695 |
| D052638 | Particulate Matter | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of SQSTM1 mRNA] | 17655762 |
| D052638 | Particulate Matter | Particulate Matter affects the expression of SQSTM1 mRNA | 17655762 |
| D052638 | Particulate Matter | Particulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SQSTM1 mRNA] | 17655762 |
| D052638 | Particulate Matter | Particulate Matter results in decreased expression of SQSTM1 protein | 28867211 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of SQSTM1 protein | 25498254 |
| D052638 | Particulate Matter | [Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 protein | 28013216 |
| C568608 | PCI 5002 | [PCI 5002 co-treated with Zinc] results in increased expression of SQSTM1 mRNA | 18593933 |
| C517827 | pentabrominated diphenyl ether 100 | [Ammonium Chloride co-treated with pentabrominated diphenyl ether 100] results in increased expression of SQSTM1 protein | 27234317 |
| C086401 | pentabromodiphenyl ether | pentabromodiphenyl ether results in increased expression of SQSTM1 mRNA | 26705709 |
| C076994 | perfluorooctane sulfonic acid | perfluorooctane sulfonic acid results in decreased expression of SQSTM1 mRNA | 18692542 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of SQSTM1 protein | 26879310 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of SQSTM1 mRNA | 26879310 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in increased expression of SQSTM1 protein | 26879310 |
| D026023 | Permethrin | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA | 28659758 |
| D010634 | Phenobarbital | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SQSTM1 mRNA] | 19482888 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of SQSTM1 mRNA | 23091169 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of SQSTM1 mRNA | 19482888 |
| D019800 | Phenol | Phenol results in increased expression of SQSTM1 mRNA | 26198647 |
| D010656 | Phenylephrine | Phenylephrine results in decreased expression of SQSTM1 mRNA | 18158353 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SQSTM1 mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in increased expression of SQSTM1 mRNA | 26272509 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SQSTM1 mRNA | 19710929 |
| D010894 | Piroxicam | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of SQSTM1 mRNA] | 21858171 |
| D010894 | Piroxicam | Piroxicam results in decreased expression of SQSTM1 mRNA | 21858171 |
| D010936 | Plant Extracts | Plant Extracts results in increased expression of SQSTM1 mRNA | 21920417 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls analog results in decreased expression of SQSTM1 mRNA | 16474171 |
| D059808 | Polyphenols | Polyphenols results in decreased expression of SQSTM1 mRNA | 16293270 |
| C027373 | potassium chromate(VI) | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SQSTM1 mRNA | 22079256 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in increased expression of SQSTM1 mRNA | 22079256 |
| D011285 | Pregnenolone Carbonitrile | Pregnenolone Carbonitrile results in increased expression of SQSTM1 mRNA | 19162173 |
| D011335 | Proadifen | Proadifen results in increased expression of SQSTM1 protein | 26964495 |
| D011374 | Progesterone | Progesterone results in increased expression of SQSTM1 mRNA | 18037150 |
| C033607 | puerarin | puerarin inhibits the reaction [lead nitrate results in increased expression of SQSTM1 protein] | 27762461 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of SQSTM1 protein] | 25881548 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SQSTM1 protein] | 27393035 |
| C432165 | pyrazolanthrone | pyrazolanthrone results in decreased expression of SQSTM1 protein | 27393035 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | 27667695 |
| C432165 | pyrazolanthrone | pyrazolanthrone inhibits the reaction [Colistin results in increased degradation of SQSTM1 protein] | 28842171 |
| C432165 | pyrazolanthrone | pyrazolanthrone results in increased expression of SQSTM1 protein | 24833599 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SQSTM1 mRNA | 28659758 |
| C005719 | pyrovalerone | Acetylcysteine inhibits the reaction [pyrovalerone analog results in decreased expression of SQSTM1 protein] | 28578026 |
| C005719 | pyrovalerone | pyrovalerone analog results in decreased expression of SQSTM1 protein | 28578026 |
| D011794 | Quercetin | pyrazolanthrone inhibits the reaction [Quercetin results in increased expression of SQSTM1 protein] | 25881548 |
| D011794 | Quercetin | Quercetin results in increased expression of SQSTM1 mRNA | 21632981|2619864 |
| D020849 | Raloxifene Hydrochloride | Raloxifene Hydrochloride results in increased expression of SQSTM1 mRNA | 15576828 |
| D012110 | Reserpine | Reserpine results in increased expression of SQSTM1 mRNA | 26198647 |
| C059514 | resveratrol | 3-methyladenine inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C059514 | resveratrol | "6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein]" | 25943029 |
| C059514 | resveratrol | Adenylyl Cyclase Inhibitors inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C059514 | resveratrol | bafilomycin A1 inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 24145604|2594302 |
| C059514 | resveratrol | bafilomycin A inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein]] | 24451142 |
| C059514 | resveratrol | Chloroquine inhibits the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C059514 | resveratrol | PRKACA protein promotes the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C059514 | resveratrol | [resveratrol co-treated with Ammonium Chloride] results in increased expression of SQSTM1 protein | 21778691 |
| C059514 | resveratrol | [resveratrol co-treated with bafilomycin A1] results in increased expression of SQSTM1 protein | 21778691 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein] | 24451142 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24304514 |
| C059514 | resveratrol | resveratrol results in decreased expression of SQSTM1 protein | 24451142 |
| C059514 | resveratrol | resveratrol results in increased degradation of SQSTM1 protein | 24145604|2594302 |
| C059514 | resveratrol | resveratrol results in increased expression of SQSTM1 protein | 21778691 |
| C059514 | resveratrol | SIRT1 protein promotes the reaction [resveratrol results in increased degradation of SQSTM1 protein] | 25943029 |
| C059514 | resveratrol | [TNF protein co-treated with resveratrol] results in increased degradation of SQSTM1 protein | 24145604 |
| C059514 | resveratrol | bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]] | 24889822 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24304514 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein] | 24889822 |
| C059514 | resveratrol | resveratrol results in increased expression of SQSTM1 protein | 25505154 |
| C059514 | resveratrol | RAB7A protein promotes the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| C059514 | resveratrol | resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| C059514 | resveratrol | resveratrol promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| C059514 | resveratrol | SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| C059514 | resveratrol | sirtinol inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| C447880 | retene | [Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in increased expression of SQSTM1 mRNA | 22120849 |
| C009166 | retinol acetate | retinol acetate results in increased expression of SQSTM1 mRNA | 16772331 |
| C064758 | Ro 31-8220 | Ro 31-8220 inhibits the reaction [SQSTM1 protein results in increased expression of NQO1 protein] | 17360324 |
| D012402 | Rotenone | bafilomycin A inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein]] | 24451142 |
| D012402 | Rotenone | resveratrol inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein] | 24451142 |
| D012402 | Rotenone | Rotenone results in increased expression of SQSTM1 protein | 24451142 |
| D012402 | Rotenone | SQSTM1 protein results in decreased susceptibility to Rotenone | 17360324 |
| D012402 | Rotenone | [bafilomycin A1 co-treated with Rotenone] results in increased expression of SQSTM1 protein | 26031332 |
| D012402 | Rotenone | Rotenone results in increased expression of SQSTM1 mRNA | 19304788 |
| D012402 | Rotenone | Rotenone results in increased expression of SQSTM1 protein | 26031332 |
| D012402 | Rotenone | SESN2 protein inhibits the reaction [Rotenone results in increased expression of SQSTM1 protein] | 26031332 |
| D012402 | Rotenone | GAPDH mutant form promotes the reaction [Rotenone results in decreased expression of SQSTM1 protein] | 25725130 |
| D012402 | Rotenone | Rotenone results in decreased expression of SQSTM1 protein | 24036476|2572513 |
| C064116 | S-(1,1,2,2-tetrafluoroethyl)cysteine | "S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of SQSTM1 mRNA" | 16678137 |
| C496827 | salubrinal | salubrinal promotes the reaction [MAP3K5 protein results in increased degradation of SQSTM1 protein] | 20929985 |
| C496827 | salubrinal | salubrinal promotes the reaction [[Paraquat co-treated with MAP3K5 protein] results in increased degradation of SQSTM1 protein] | 20929985 |
| C040256 | SAN 58035 | SAN 58035 promotes the reaction [Cholesterol Esters results in increased expression of SQSTM1 protein] | 28275691 |
| D012503 | Saponins | Saponins results in decreased expression of SQSTM1 protein | 28088315 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in increased expression of SQSTM1 mRNA | 23806026|2589566 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of SQSTM1 mRNA | 25351596 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of SQSTM1 mRNA | 19073995 |
| D012834 | Silver | Silver results in increased expression of SQSTM1 mRNA | 26014281|2655175 |
| D012834 | Silver | Silver results in increased expression of SQSTM1 protein | 28987793 |
| D012834 | Silver | Silver results in increased expression of SQSTM1 mRNA | 27131904 |
| D020123 | Sirolimus | resveratrol inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24304514 |
| D020123 | Sirolimus | Sirolimus results in decreased expression of SQSTM1 protein | 19773376|2430451 |
| D020123 | Sirolimus | bafilomycin A1 inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24238063 |
| D020123 | Sirolimus | CD38 mutant form inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24238063 |
| D020123 | Sirolimus | Niacinamide inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24238063 |
| D020123 | Sirolimus | resveratrol inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24304514 |
| D020123 | Sirolimus | Sirolimus results in decreased expression of SQSTM1 protein | 24238063|2430451 |
| D020123 | Sirolimus | [bafilomycin A1 co-treated with bisphenol A co-treated with Sirolimus] results in increased expression of SQSTM1 protein | 26139607 |
| D020123 | Sirolimus | Sirolimus inhibits the reaction [manganese chloride results in increased expression of SQSTM1 protein] | 29222055 |
| D020123 | Sirolimus | Sirolimus promotes the reaction [bisphenol A results in decreased expression of SQSTM1 protein] | 26139607 |
| D020123 | Sirolimus | "Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]]" | 29128638 |
| D020123 | Sirolimus | Sirolimus results in decreased expression of SQSTM1 protein | 29218509 |
| C439060 | sirtinol | sirtinol inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein]] | 24889822 |
| C439060 | sirtinol | sirtinol promotes the reaction [Hydrogen Peroxide results in increased expression of SQSTM1 protein] | 24889822 |
| D012906 | Smoke | Smoke results in increased expression of SQSTM1 mRNA | 21095227 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of SQSTM1 mRNA | 23922661 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of SQSTM1 mRNA | 12745069 |
| C009277 | sodium arsenate | sodium arsenate results in increased expression of SQSTM1 protein alternative form | 12745069 |
| C017947 | sodium arsenite | NFE2L2 protein promotes the reaction [sodium arsenite results in increased expression of SQSTM1 mRNA] | 28125038 |
| C017947 | sodium arsenite | NFE2L2 protein promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein] | 28125038 |
| C017947 | sodium arsenite | sodium arsenite promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 28125038 |
| C017947 | sodium arsenite | sodium arsenite promotes the reaction [SQSTM1 protein binds to SNAI1 protein] | 28888487 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of and affects the localization of SQSTM1 protein | 23589329 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of and affects the splicing of SQSTM1 mRNA | 25879800 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of and results in increased phosphorylation of SQSTM1 protein | 28229933 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SQSTM1 mRNA | 24516582|2549360 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SQSTM1 protein | 27413109|2812503 |
| C017947 | sodium arsenite | SQSTM1 protein affects the reaction [sodium arsenite results in decreased expression of CDH1 protein] | 28888487 |
| C017947 | sodium arsenite | SQSTM1 protein affects the reaction [sodium arsenite results in increased expression of SNAI1 protein] | 28888487 |
| C017947 | sodium arsenite | SQSTM1 protein affects the reaction [sodium arsenite results in increased expression of VIM protein] | 28888487 |
| C017947 | sodium arsenite | SQSTM1 protein promotes the reaction [sodium arsenite results in increased expression of and results in increased activity of NFE2L2 protein] | 23589329 |
| C017947 | sodium arsenite | SQSTM1 protein promotes the reaction [sodium arsenite results in increased expression of CDKN1A mRNA] | 28125038 |
| C017947 | sodium arsenite | SQSTM1 protein promotes the reaction [sodium arsenite results in increased expression of GCLC mRNA] | 28125038 |
| C017947 | sodium arsenite | SQSTM1 protein promotes the reaction [sodium arsenite results in increased expression of HMOX1 mRNA] | 28125038 |
| C017947 | sodium arsenite | SQSTM1 protein promotes the reaction [sodium arsenite results in increased expression of NQO1 mRNA] | 28125038 |
| C017947 | sodium arsenite | SQSTM1 protein results in increased susceptibility to sodium arsenite | 23589329 |
| C017947 | sodium arsenite | sulforafan inhibits the reaction [sodium arsenite affects the localization of SQSTM1 protein] | 23589329 |
| C017947 | sodium arsenite | Estrogens promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein] | 26631322 |
| C017947 | sodium arsenite | SOCS3 mutant form inhibits the reaction [Estrogens promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]] | 26631322 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SQSTM1 mRNA | 11525245|1601473 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SQSTM1 protein | 26631322|2812503 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of SQSTM1 protein alternative form | 12745069 |
| C016104 | sodium bichromate | [Benzo(a)pyrene co-treated with sodium bichromate] results in increased expression of SQSTM1 mRNA | 21632023 |
| C016104 | sodium bichromate | sodium bichromate results in decreased expression of SQSTM1 mRNA | 22155349 |
| C016104 | sodium bichromate | sodium bichromate results in increased expression of SQSTM1 mRNA | 22155349 |
| C016104 | sodium bichromate | sodium bichromate results in increased expression of SQSTM1 mRNA | 22110744 |
| D018038 | Sodium Selenite | "[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of SQSTM1 protein" | 28757135 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of SQSTM1 mRNA | 24383545 |
| D053260 | Soot | Soot results in increased expression of SQSTM1 mRNA | 26551751 |
| D013267 | Stilbenes | Stilbenes results in decreased expression of SQSTM1 protein | 23059970 |
| D013311 | Streptozocin | bafilomycin A1 inhibits the reaction [resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]] | 24889822 |
| D013311 | Streptozocin | resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein] | 24889822 |
| D013311 | Streptozocin | Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] | 24889822 |
| D013311 | Streptozocin | Streptozocin results in increased expression of SQSTM1 protein | 24889822 |
| D004113 | Succimer | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SQSTM1 mRNA | 21641980 |
| D004113 | Succimer | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SQSTM1 mRNA | 26378955 |
| C016766 | sulforafan | sulforafan inhibits the reaction [sodium arsenite affects the localization of SQSTM1 protein] | 23589329 |
| D013467 | Sulindac | Sulindac results in increased expression of SQSTM1 mRNA | 11906190 |
| C025462 | sulindac sulfide | sulindac sulfide results in increased expression of SQSTM1 mRNA | 16184548 |
| C473643 | sulphoraphene | sulphoraphene results in increased expression of SQSTM1 mRNA | 29247643 |
| C473643 | sulphoraphene | sulphoraphene results in increased expression of SQSTM1 protein | 29247643 |
| C473478 | sunitinib | Chloroquine inhibits the reaction [sunitinib results in decreased expression of SQSTM1 protein] | 24751611 |
| C473478 | sunitinib | sunitinib results in decreased expression of SQSTM1 protein | 24751611 |
| D013629 | Tamoxifen | Tamoxifen results in increased expression of SQSTM1 protein | 25301941 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of SQSTM1 mRNA | 17555576 |
| D013656 | Taurocholic Acid | Taurocholic Acid results in increased expression of SQSTM1 protein | 24189133 |
| C004648 | testosterone enanthate | testosterone enanthate affects the expression of SQSTM1 mRNA | 17440010 |
| C020806 | tetrabromobisphenol A | tetrabromobisphenol A results in increased expression of SQSTM1 mRNA | 25172293 |
| C000591600 | tetrachlorobenzoquinone | BACH1 protein inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SQSTM1 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | NFE2L2 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of SQSTM1 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | pyrazolanthrone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SQSTM1 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | SQSTM1 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of HMOX1 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | SQSTM1 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of NFE2L2 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | SQSTM1 protein promotes the reaction [tetrachlorobenzoquinone results in increased expression of NQO1 protein] | 27393035 |
| C000591600 | tetrachlorobenzoquinone | tetrachlorobenzoquinone results in increased expression of SQSTM1 protein | 27393035 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SQSTM1 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SQSTM1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SQSTM1 mRNA | 15034205 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SQSTM1 mRNA | 22298810 |
| D013752 | Tetracycline | Tetracycline affects the expression of SQSTM1 mRNA | 25064622 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of SQSTM1 mRNA | 26198647 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of SQSTM1 mRNA | 25613284 |
| C009438 | tetrandrine | tetrandrine results in decreased expression of SQSTM1 protein | 25266202 |
| D013853 | Thioacetamide | Thioacetamide affects the expression of SQSTM1 mRNA | 25064622 |
| D013893 | Thiram | Thiram results in increased expression of SQSTM1 mRNA | 24211530 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of SQSTM1 mRNA | 22363418|2740439 |
| D019772 | Topotecan | [oxaliplatin co-treated with Topotecan] results in increased expression of SQSTM1 mRNA | 25729387 |
| D014212 | Tretinoin | [Tretinoin co-treated with arsenic trioxide] results in increased expression of SQSTM1 mRNA | 15894607 |
| D014212 | Tretinoin | Tretinoin results in increased expression of SQSTM1 mRNA | 15894607 |
| C034613 | triacsin C | triacsin C results in increased expression of SQSTM1 mRNA | 16704987 |
| D014241 | Trichloroethylene | PPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of SQSTM1 mRNA] | 15363585 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SQSTM1 mRNA | 15901671 |
| C046488 | trimethyltin | trimethyltin results in decreased degradation of SQSTM1 protein | 26459185 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in increased expression of SQSTM1 mRNA" | 26179874 |
| C057693 | troglitazone | troglitazone results in increased expression of SQSTM1 mRNA | 19140230 |
| C002802 | tungsten carbide | [tungsten carbide co-treated with Cobalt] results in increased expression of SQSTM1 mRNA | 18078969 |
| D014415 | Tunicamycin | Tunicamycin results in increased expression of SQSTM1 mRNA | 22378314 |
| C113580 | U 0126 | U 0126 inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | 27667695 |
| D014520 | Urethane | Urethane results in increased expression of SQSTM1 mRNA | 28818685 |
| C073339 | usnic acid | usnic acid results in increased degradation of SQSTM1 protein | 25078063 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of SQSTM1 mRNA | 25064622 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SQSTM1 mRNA | 15901671 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of SQSTM1 mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SQSTM1 mRNA | 23179753|2800136 |
| D014635 | Valproic Acid | Valproic Acid results in increased methylation of SQSTM1 gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of SQSTM1 mRNA | 17292431 |
| D001335 | Vehicle Emissions | oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of SQSTM1 mRNA] | 17655762 |
| D001335 | Vehicle Emissions | Vehicle Emissions affects the expression of SQSTM1 mRNA | 17655762 |
| D001335 | Vehicle Emissions | Vehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of SQSTM1 mRNA] | 17655762 |
| D001335 | Vehicle Emissions | [Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 protein | 28013216 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased expression of SQSTM1 protein | 25498254 |
| D000069470 | Venlafaxine Hydrochloride | Venlafaxine Hydrochloride results in decreased expression of SQSTM1 mRNA | 25423262 |
| D014750 | Vincristine | [cotylenin A co-treated with Vincristine] results in increased degradation of SQSTM1 protein | 25672400 |
| D014750 | Vincristine | Vincristine results in increased expression of SQSTM1 mRNA | 23649840 |
| D009536 | Niacinamide | Niacinamide inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] | 24238063 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of SQSTM1 mRNA | 23410634 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of SQSTM1 mRNA | 25270620 |
| C009687 | wortmannin | [wortmannin co-treated with Ethanol] results in increased expression of SQSTM1 protein | 22459179 |
| C009687 | wortmannin | wortmannin results in decreased expression of SQSTM1 protein | 22459179 |
| C009687 | wortmannin | wortmannin results in increased expression of SQSTM1 protein | 22459179 |
| D015032 | Zinc | [PCI 5002 co-treated with Zinc] results in increased expression of SQSTM1 mRNA | 18593933 |
| D015034 | Zinc Oxide | Zinc Oxide results in increased expression of SQSTM1 protein | 29289694 |
| D019287 | Zinc Sulfate | 3-methyladenine inhibits the reaction [Zinc Sulfate results in decreased expression of SQSTM1 protein] | 28803810 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased expression of SQSTM1 protein | 28803810 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in increased expression of SQSTM1 mRNA | 28803810 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0004674 | protein serine/threonine kinase activity | - | NAS | 8618896 |
| GO:0005080 | protein kinase C binding | - | IBA | 21873635 |
| GO:0005080 | protein kinase C binding | - | IPI | 14676191 |
| GO:0005515 | protein binding | - | IPI | 8618896 8702753 12857745 14676191 16169070 16189514 16874300 17353931 17389358 17580304 18083104 19229298 19250911 19427866 19615732 20010802 20168092 20173742 20357094 20417604 20452972 20551902 20562859 20808283 21149568 21900206 21988832 22178386 22190034 22421968 23274085 23459205 24089205 24189400 24316673 24668264 25026213 25040165 25126726 25416956 25422469 25686248 25910212 26344566 26347139 26524528 27103069 27107014 27728806 28404643 |
| GO:0008270 | zinc ion binding | - | IEA | - |
| GO:0019899 | enzyme binding | - | IPI | 27368102 |
| GO:0019901 | protein kinase binding | - | IDA | 8650207 |
| GO:0030971 | receptor tyrosine kinase binding | - | TAS | 8650207 |
| GO:0031625 | ubiquitin protein ligase binding | - | IDA | 27368102 |
| GO:0031625 | ubiquitin protein ligase binding | - | IPI | 25127057 27368102 |
| GO:0035255 | ionotropic glutamate receptor binding | - | ISS | - |
| GO:0042169 | SH2 domain binding | - | IDA | 8650207 |
| GO:0042802 | identical protein binding | - | IPI | 16169070 20562859 21900206 25416956 25686248 |
| GO:0042803 | protein homodimerization activity | - | IEA | - |
| GO:0043130 | ubiquitin binding | - | IDA | 12857745 |
| GO:0043130 | ubiquitin binding | - | TAS | - |
| GO:0070530 | K63-linked polyubiquitin modification-dependent protein binding | - | IBA | 21873635 |
| GO:0070530 | K63-linked polyubiquitin modification-dependent protein binding | - | IDA | 28404643 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | - | IEA | - |
| GO:0000422 | autophagy of mitochondrion | - | NAS | 20098416 |
| GO:0000423 | mitophagy | - | IBA | 21873635 |
| GO:0000423 | mitophagy | - | IGI | 20457763 |
| GO:0001934 | positive regulation of protein phosphorylation | - | IEA | - |
| GO:0002376 | immune system process | - | IEA | - |
| GO:0002931 | response to ischemia | - | IEA | - |
| GO:0006468 | protein phosphorylation | - | IEA | - |
| GO:0006511 | ubiquitin-dependent protein catabolic process | - | TAS | 8702753 |
| GO:0006914 | autophagy | - | IMP | 17580304 |
| GO:0006914 | autophagy | - | TAS | 19816510 |
| GO:0006915 | apoptotic process | - | IEA | - |
| GO:0007005 | mitochondrion organization | - | IBA | 21873635 |
| GO:0007032 | endosome organization | - | IBA | 21873635 |
| GO:0007032 | endosome organization | - | IDA | 27368102 |
| GO:0008104 | protein localization | - | TAS | 8650207 |
| GO:0010821 | regulation of mitochondrion organization | - | NAS | 20890124 |
| GO:0016197 | endosomal transport | - | TAS | 12857745 |
| GO:0016236 | macroautophagy | - | IMP | 20168092 |
| GO:0016236 | macroautophagy | - | ISS | - |
| GO:0016236 | macroautophagy | - | TAS | - |
| GO:0030154 | cell differentiation | - | IEA | - |
| GO:0035556 | intracellular signal transduction | - | TAS | 8650207 |
| GO:0035973 | aggrephagy | - | IBA | 21873635 |
| GO:0035973 | aggrephagy | - | IPI | 28404643 |
| GO:0043065 | positive regulation of apoptotic process | - | TAS | - |
| GO:0043066 | negative regulation of apoptotic process | - | TAS | - |
| GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | - | IMP | 12857745 |
| GO:0044130 | negative regulation of growth of symbiont in host | - | IEA | - |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | - | TAS | 12857745 |
| GO:0046578 | regulation of Ras protein signal transduction | - | NAS | 8618896 |
| GO:0051291 | protein heterooligomerization | - | IEA | - |
| GO:0061635 | regulation of protein complex stability | - | IDA | 25127057 |
| GO:0061912 | selective autophagy | - | IMP | 22622177 |
| GO:0070498 | interleukin-1-mediated signaling pathway | - | TAS | - |
| GO:0098780 | response to mitochondrial depolarisation | - | IGI | 20457763 |
| GO:1900273 | positive regulation of long-term synaptic potentiation | - | ISS | - |
| GO:1903078 | positive regulation of protein localization to plasma membrane | - | ISS | - |
| GO:1905719 | protein localization to perinuclear region of cytoplasm | - | IDA | 27368102 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000407 | phagophore assembly site | - | IEA | - |
| GO:0000932 | P-body | - | IDA | 20357094 |
| GO:0005654 | nucleoplasm | - | TAS | - |
| GO:0005737 | cytoplasm | - | IDA | 20168092 |
| GO:0005770 | late endosome | - | IEA | - |
| GO:0005776 | autophagosome | - | IBA | 21873635 |
| GO:0005776 | autophagosome | - | IDA | 17580304 19640926 20168092 22948227 24954904 |
| GO:0005783 | endoplasmic reticulum | - | IEA | - |
| GO:0005829 | cytosol | - | IDA | - |
| GO:0005829 | cytosol | - | TAS | 8650207 |
| GO:0016234 | inclusion body | - | IDA | 20168092 |
| GO:0016235 | aggresome | - | IBA | 21873635 |
| GO:0016605 | PML body | - | IDA | 20168092 |
| GO:0030017 | sarcomere | - | IEA | - |
| GO:0043231 | intracellular membrane-bounded organelle | - | IDA | - |
| GO:0044753 | amphisome | - | IBA | 21873635 |
| GO:0044753 | amphisome | - | IDA | 19640926 |
| GO:0044754 | autolysosome | - | IDA | 19640926 |
| GO:0070062 | extracellular exosome | - | HDA | 19056867 |
| GO:0097225 | sperm midpiece | - | IEA | - |
| GO:0097413 | Lewy body | - | IEA | - |
| KEGG ID | KEGG Term |
|---|---|
| hsa04380 | Osteoclast differentiation |
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-1280215 | Cytokine Signaling in Immune system | TAS |
| R-HSA-162582 | Signal Transduction | TAS |
| R-HSA-168256 | Immune System | TAS |
| R-HSA-193639 | p75NTR signals via NF-kB | TAS |
| R-HSA-193704 | p75 NTR receptor-mediated signalling | TAS |
| R-HSA-204998 | Cell death signalling via NRAGE, NRIF and NADE | TAS |
| R-HSA-205043 | NRIF signals cell death from the nucleus | TAS |
| R-HSA-209543 | p75NTR recruits signalling complexes | TAS |
| R-HSA-209560 | NF-kB is activated and signals survival | TAS |
| R-HSA-446652 | Interleukin-1 family signaling | TAS |
| R-HSA-449147 | Signaling by Interleukins | TAS |
| R-HSA-5205647 | Mitophagy | TAS |
| R-HSA-5205685 | Pink/Parkin Mediated Mitophagy | TAS |
| R-HSA-73887 | Death Receptor Signalling | TAS |
| R-HSA-9020702 | Interleukin-1 signaling | TAS |