Gene: CCNA2

890
CCN1|CCNA
cyclin A2
protein-coding
4q27
Ensembl:ENSG00000145386 MIM:123835 Vega:OTTHUMG00000133072 UniprotKB:P20248
NG_052974.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.822e-1 (AD)  5.509e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLFNL10.787
TLR90.787
DNA20.785
KLK140.782
BNIPL0.779
SNRNP480.773
JMJD60.773
MIA0.765
C7orf610.754
CHORDC10.752

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRSS27-0.476
HPDL-0.41
HES5-0.4
RBM3-0.387
CCT6B-0.377
CACNG1-0.375
MYLK2-0.374
ALDH1L1-AS2-0.366
HMGB3-0.365
HSD17B8-0.364

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB020914-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-YlamineSmall MoleculeExperimentalTarget
DB024076-O-Cyclohexylmethyl GuanineSmall MoleculeExperimentalTarget
DB02833[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-AmineSmall MoleculeExperimentalTarget
DB029154-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-[4-(trifluoromethyl)phenyl]-2-pyrimidinamineSmall MoleculeExperimentalTarget
DB068444-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB06944N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamideSmall Molecule-ExperimentalTarget
DB069482-ANILINO-6-CYCLOHEXYLMETHOXYPURINESmall MoleculeExperimentalTarget
DB07126O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINESmall MoleculeExperimentalTarget
DB07137(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDESmall MoleculeExperimentalTarget
DB07164N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amineSmall MoleculeExperimentalTarget
DB072036-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINESmall MoleculeExperimentalTarget
DB074715-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDESmall MoleculeExperimentalTarget
DB075334-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB075344-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB075384-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB075394-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACIDSmall MoleculeExperimentalTarget
DB07562N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINESmall MoleculeExperimentalTarget
DB076884-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB078521-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACIDSmall MoleculeExperimentalTarget
DB081784-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amineSmall MoleculeExperimentalTarget
DB081824-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amineSmall MoleculeExperimentalTarget
DB08218HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUMSmall MoleculeExperimentalTarget
DB082194-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINESmall MoleculeExperimentalTarget
DB082336-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINESmall MoleculeExperimentalTarget
DB082414-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDESmall MoleculeExperimentalTarget
DB082483-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDESmall MoleculeExperimentalTarget
DB08285(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-olSmall MoleculeExperimentalTarget
DB083093-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OLSmall MoleculeExperimentalTarget
DB083551-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acidSmall MoleculeExperimentalTarget
DB08463(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-olSmall MoleculeExperimentalTarget
DB085271-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDESmall MoleculeExperimentalTarget
DB085724-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDESmall MoleculeExperimentalTarget
DB086949-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-olSmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of CCNA2 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA"23626729
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1A protein]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1B protein]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of CCNA2 protein"21705713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 mRNA"22698814|2362672
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 protein"12807759|1538217
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Androstanols inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 protein]"12807759
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"CTNNB1 gene mutant form promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 mRNA]"21705713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"CTNNB1 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 mRNA]"21705713
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein]]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1A protein]]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1A protein]]] which results in decreased activity of CDK2 protein"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1B protein]]"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1B protein]]] which results in decreased activity of CDK2 protein"20637255
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 protein]"20637255
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNA2 protein"15729575
C07258116-hydroxycleroda-3,13(14)-dien-15,16-olide"16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased expression of CCNA2 protein"21530604
C00202917alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol"17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CCNA2 protein"16019103
C495172(19Z)-halichondramide(19Z)-halichondramide results in decreased expression of CCNA2 protein23147639
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of CCNA2 mRNA28329830
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CCNA2 mRNA"26988655
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CCNA2 mRNA"20566336
C5877342,3,5-trichloro-6-phenyl-(1,4)benzoquinone"2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in decreased expression of CCNA2 protein"26451628
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone results in increased expression of CCNA2 mRNA"19031421
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CCNA2 mRNA"23146750
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of CCNA2 mRNA"15201435
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of CCNA2 mRNA"20713471
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of CCNA2 protein17148679
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased expression of CCNA2 protein]14971663
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CCNA2 protein"10728688
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNA2 protein"16120219
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNA2 mRNA"23681119
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of CCNA2 protein20469912
C1202752-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNA2 protein11468187
C0228302-methoxyestradiol2-methoxyestradiol results in decreased expression of CCNA2 protein23967052
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCNA2 protein]24013123
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNA2 mRNA"23146750
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with TNF protein] results in increased expression of CCNA2 mRNA"17557910
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNA2 mRNA"23196670
C0917683'-methoxy-4'-nitroflavone3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCNA2 protein]24013123
C0388644-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased expression of CCNA2 protein]"11348869
C0388644-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]"12421932
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of CCNA2 mRNA"25380136
C0101184,4'-dihydroxystilbene"4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA"19496085
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in decreased expression of CCNA2 mRNA"17440966
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CCNA2 mRNA12419474
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CCNA2 mRNA19191707
C0642974-hydroxystilbene4-hydroxystilbene results in increased expression of CCNA2 mRNA19496085
C0415944-nonylphenol4-nonylphenol results in decreased expression of CCNA2 protein26804764
C4948984-oxofenretinide4-oxofenretinide results in decreased expression of CCNA2 protein16540676
C5036435-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin"5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin results in decreased expression of CCNA2 protein"16179969
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in decreased expression of CCNA2 protein16179969
C5805985-OH-BDE-475-OH-BDE-47 results in increased expression of CCNA2 mRNA26988655
C5319376-O-angeloylenolin6-O-angeloylenolin results in decreased expression of CCNA2 protein21192922
C5805996-OH-BDE-476-OH-BDE-47 results in increased expression of CCNA2 mRNA26988655
C072876A 771726A 771726 results in increased expression of CCNA2 protein12181422
C542662AC 93253AC 93253 results in decreased expression of CCNA2 mRNA25912555
D000082AcetaminophenAcetaminophen results in decreased expression of CCNA2 mRNA26690555
D000082AcetaminophenAcetaminophen results in decreased expression of CCNA2 mRNA17942131
D000111AcetylcysteineAcetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased expression of CCNA2 protein]28506552
D000111AcetylcysteineAcetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNA2 protein]24909818
D020106AcrylamideAcrylamide results in increased expression of CCNA2 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of CCNA2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CCNA2 mRNA23630614
C412373AG 1879AG 1879 inhibits the reaction [Estradiol results in increased expression of CCNA2 mRNA]25616260
C430898AGN 194204AGN 194204 inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased expression of CCNA2 protein]11348869
C430898AGN 194204AGN 194204 results in decreased expression of CCNA2 protein21080969
C031143AICA ribonucleotideAICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]12730239
C031143AICA ribonucleotideAICA ribonucleotide results in decreased expression of CCNA2 mRNA12730239
C031143AICA ribonucleotideAICA ribonucleotide results in decreased expression of CCNA2 protein12730239
C103303alitretinoinalitretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased expression of CCNA2 protein]11348869
C002055alloseallose results in decreased expression of CCNA2 mRNA18930000
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of CCNA2 protein15647840
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of CCNA2 mRNA17023530
C000607033alpha-terthienylmethanolAcetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased expression of CCNA2 protein]28506552
C000607033alpha-terthienylmethanolalpha-terthienylmethanol results in increased expression of CCNA2 protein28506552
C077990alvocidibalvocidib results in decreased expression of and results in decreased activity of CCNA2 protein16731754
C413760aminoflavoneaminoflavone results in increased expression of CCNA224885022
D006710HomocysteineDactinomycin inhibits the reaction [Homocysteine results in increased expression of CCNA2 mRNA]8550827
D006710HomocysteineHomocysteine promotes the reaction [ATF1 protein binds to CCNA2 promoter]8550827
D006710HomocysteineHomocysteine results in increased expression of CCNA2 mRNA8550827
D006710HomocysteineHomocysteine results in increased expression of CCNA2 protein8550827
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CCNA2 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of CCNA2 mRNA"22863853
D000677AmsacrineAmsacrine results in increased degradation of and results in decreased expression of CCNA2 protein11774253
C030419andrographolideandrographolide inhibits the reaction [CCNA2 protein binds to CDK2 protein]18619950
C030419andrographolideandrographolide results in decreased expression of CCNA2 protein18619950
D000732Androstanols"Androstanols inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 protein]"12807759
C034020anthraceneanthracene results in decreased expression of CCNA2 protein28803881
C034020anthracene[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein28803881
D000968Antimycin AAntimycin A inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]12730239
D000968Antimycin AAntimycin A results in decreased expression of CCNA2 mRNA12730239
D000968Antimycin AAntimycin A results in decreased expression of CCNA2 protein12730239
D016590AphidicolinAphidicolin results in increased expression of CCNA2 mRNA14738865
C102351apicidinapicidin results in decreased expression of CCNA2 mRNA19070610
D001151ArsenicArsenic results in increased expression of CCNA2 mRNA11134558
C006632arsenic trioxidearsenic trioxide affects the expression of CCNA2 mRNA28786057
C006632arsenic trioxidearsenic trioxide results in decreased expression of CCNA2 mRNA20458559
C006632arsenic trioxidearsenic trioxide results in decreased expression of CCNA2 protein12480548|2517435
C015001arsenitearsenite results in decreased expression of CCNA2 mRNA18929588
C010302aspidin BBaspidin BB results in increased expression of CCNA2 protein23628508
D001241AspirinAspirin inhibits the reaction [Methotrexate results in increased expression of CCNA2 protein]23799623
D001280AtrazineAtrazine results in increased expression of CCNA2 mRNA22378314|2561626
C105832auraptenaurapten affects the expression of CCNA2 mRNA23320178
D001374Azacitidine[Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA18720364
D001374AzacitidineAzacitidine results in decreased expression of CCNA2 mRNA20823114
D001379AzathioprineAzathioprine results in decreased expression of CCNA2 mRNA22623647
C547126AZM551248AZM551248 results in increased expression of CCNA2 mRNA22323515
C006680baicaleinbaicalein results in decreased expression of CCNA2 protein21457722
C038044baicalinbaicalin results in decreased expression of CCNA2 protein21457722
D001507BeclomethasoneBeclomethasone results in increased expression of CCNA2 mRNA23656298
C487081belinostatbelinostat results in decreased expression of CCNA2 mRNA19606018
C030935benz(a)anthraceneAHR affects the reaction [benz(a)anthracene results in increased expression of CCNA2 protein]17141280
C030935benz(a)anthracenebenz(a)anthracene results in increased activity of [CCNA2 protein binds to CDK2 protein]17141280
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CCNA2 protein17141280
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of CCNA2 mRNA16269432
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CCNA2 mRNA26377693
C006703benzo(b)fluorantheneAHR affects the reaction [benzo(b)fluoranthene results in increased activity of [CCNA2 protein binds to CDK2 protein]]17141280
C006703benzo(b)fluorantheneAHR affects the reaction [benzo(b)fluoranthene results in increased expression of CCNA2 protein]17141280
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased activity of [CCNA2 protein binds to CDK2 protein]17141280
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CCNA2 protein17141280
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNA2 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNA2 mRNA16120219|1626943
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNA2 protein16120219
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNA2 mRNA17942131|1977048
D001564Benzo(a)pyreneAHR affects the reaction [Benzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein]]17141280
D001564Benzo(a)pyreneAHR affects the reaction [Benzo(a)pyrene results in increased expression of CCNA2 protein]17141280
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein]17141280
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CCNA2 protein17141280
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CCNA2 mRNA"19150397|2038263
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNA2 mRNA20061341
D004958EstradiolAG 1879 inhibits the reaction [Estradiol results in increased expression of CCNA2 mRNA]25616260
D004958Estradiol[Cycloheximide co-treated with Estradiol] results in increased expression of CCNA2 mRNA15072547
D004958EstradiolESR2 protein affects the reaction [Estradiol affects the expression of CCNA2 mRNA]19434490
D004958EstradiolEstradiol affects the expression of CCNA2 mRNA19434490|2182616
D004958Estradiol[Estradiol co-treated with Parathion] results in decreased expression of CCNA2 mRNA17622325
D004958Estradiol[Estradiol co-treated with Tamoxifen] results in decreased expression of CCNA2 mRNA19434490
D004958EstradiolEstradiol results in decreased expression of CCNA2 mRNA17622325
D004958EstradiolEstradiol results in increased expression of CCNA2 mRNA15072547|1647417
D004958EstradiolEstradiol results in increased expression of CCNA2 protein17445807
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in increased expression of CCNA2 mRNA]25210133
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of CCNA2 mRNA19693291
D004958EstradiolEstradiol results in increased expression of CCNA2 mRNA11861973|2521013
D004958EstradiolEstradiol results in increased expression of CCNA2 protein15642790|1584574
D004958EstradiolLithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]15845746
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]15845746
D004958EstradiolTetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNA2 mRNA]11861973
C053541bicalutamidebicalutamide results in decreased expression of CCNA2 mRNA15887248
C006780bisphenol Abisphenol A affects the expression of CCNA2 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of CCNA2 mRNA29027980
C006780bisphenol Abisphenol A affects the expression of CCNA2 mRNA21826169
C006780bisphenol Abisphenol A results in decreased expression of CCNA2 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of CCNA2 mRNA16474171|2415670
C006780bisphenol Abisphenol A results in increased expression of CCNA2 protein21277958|2322281
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein]23222814
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNA2 mRNA28628672
C006780bisphenol AAcetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNA2 protein]24909818
C006780bisphenol Abisphenol A results in decreased expression of CCNA2 protein24909818
C006780bisphenol Abisphenol A results in increased expression of CCNA2 protein24909818
C006780bisphenol Aoligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein]24909818
C006780bisphenol Abisphenol A results in decreased expression of CCNA2 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of CCNA2 mRNA17942131|1895870
C073829Bupleuran 2IIcBupleuran 2IIc results in increased expression of CCNA2 protein14556967
D002083Butylated Hydroxyanisole[propylparaben co-treated with Butylated Hydroxyanisole] results in decreased expression of CCNA2 mRNA25086368
D002084Butylated HydroxytolueneButylated Hydroxytoluene results in increased expression of CCNA2 mRNA12867420
D002084Butylated Hydroxytoluene[Butylated Hydroxytoluene results in increased expression of FOXM1 mRNA] which results in increased expression of CCNA2 mRNA12867420
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide affects the expression of CCNA2 mRNA23410634
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of CCNA2 mRNA12414654|1241947
D002087ButyratesButyrates results in decreased expression of CCNA2 protein16007142
C584509C646 compoundC646 compound results in decreased expression of CCNA2 mRNA23698071
C584509C646 compoundC646 compound results in decreased expression of CCNA2 protein23698071
D002104CadmiumCadmium results in decreased expression of CCNA2 mRNA21120746
D002104CadmiumCadmium results in decreased expression of CCNA2 protein16730872
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CCNA2 protein20054826
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNA2 mRNA20061341
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNA2 mRNA25993096
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNA2 protein16730872
D002211CapsaicinCapsaicin results in decreased expression of CCNA2 protein19939880
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CCNA2 mRNA12759355|1748488
D002251Carbon TetrachlorideCDKN1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CCNA2 mRNA]12759355
D002251Carbon TetrachloridePLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCNA2 mRNA]16006527
C099555CD 437CD 437 results in decreased activity of [CDK2 protein binds to CCNA2 protein]10766194
D002509CephaloridineCephaloridine results in decreased expression of CCNA2 mRNA18500788
D002706ChlordanChlordan results in increased expression of CCNA2 mRNA20403969
D004390ChlorpyrifosChlorpyrifos results in decreased expression of CCNA2 mRNA21356183
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNA2 mRNA20938992
C043867cicaprostcicaprost results in decreased expression of CCNA2 mRNA12869629
C043867cicaprostcicaprost inhibits the reaction [CREB1 protein binds to CCNA2 promoter]12869629
C043867cicaprostcicaprost results in decreased expression of CCNA2 mRNA12869629
C043867cicaprostcicaprost results in decreased expression of CCNA2 protein12869629
C039671ciglitazoneciglitazone results in decreased expression of CCNA2 protein21080969
C045645cilostazolcilostazol results in decreased expression of CCNA2 protein15723965
C002471cinobufagincinobufagin results in decreased expression of CCNA2 mRNA21215801
D002953CitrininCitrinin results in increased expression of CCNA2 mRNA23856526
D002994ClofibrateClofibrate results in decreased expression of CCNA2 protein21080969
D002994ClofibrateClofibrate results in decreased expression of CCNA2 mRNA22008536
D003033Coal TarCoal Tar results in decreased expression of CCNA2 mRNA27858113
C018021cobaltous chloridecobaltous chloride results in decreased expression of CCNA2 mRNA19320972|1937684
C018021cobaltous chloridecobaltous chloride results in decreased expression of CCNA2 mRNA24386269
D003042CocaineCocaine results in decreased expression of CCNA2 mRNA18593214
D003042CocaineCocaine results in decreased expression of CCNA2 mRNA18593214
D003042CocaineCocaine affects the expression of CCNA220948987
D003300Copper[Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein15367699
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of CCNA2 mRNA20971185
D003300CopperCopper results in increased expression of CCNA2 mRNA22465980
C464760copper-1,10-phenanthroline"copper-1,10-phenanthroline results in decreased expression of CCNA2 protein"24638265
D019327Copper SulfateCopper Sulfate results in decreased expression of CCNA2 mRNA19549813
D003375Coumestrol[Coumestrol co-treated with ESR1 protein] results in increased expression of CCNA2 mRNA18310284
D003375CoumestrolCoumestrol results in decreased expression of CCNA2 protein20623010
D003375CoumestrolCoumestrol results in increased expression of CCNA2 protein20623010
D003375CoumestrolESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CCNA2 mRNA]18310284
C024015cryptolepinecryptolepine results in decreased expression of CCNA2 mRNA16120219
C024015cryptolepinecryptolepine results in decreased expression of CCNA2 protein16120219
C038106cucurbitacin Icucurbitacin I results in decreased expression of CCNA2 protein24858077
C030973cupric oxidecupric oxide results in decreased expression of CCNA2 mRNA22077320
D003471CuprizoneCuprizone results in increased expression of CCNA2 mRNA26577399
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein]23222814
D003474CurcuminCurcumin results in decreased expression of CCNA2 protein23222814
D003513Cycloheximide[Cycloheximide co-treated with Estradiol] results in increased expression of CCNA2 mRNA15072547
D003513CycloheximideCycloheximide results in decreased expression of CCNA2 mRNA15072547
D003520CyclophosphamideCyclophosphamide results in decreased expression of CCNA2 mRNA21041162
D016572CyclosporineCyclosporine results in decreased expression of CCNA2 mRNA19159671|2010694
D016572CyclosporineCyclosporine results in decreased expression of CCNA2 mRNA17942131
D016572CyclosporineCyclosporine results in increased expression of CCNA2 mRNA19770486
C017160cypermethrincypermethrin results in decreased expression of CCNA2 mRNA22528246
D003609DactinomycinDactinomycin inhibits the reaction [Homocysteine results in increased expression of CCNA2 mRNA]8550827
C004742daidzeindaidzein results in decreased expression of CCNA221161820
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of CCNA2 mRNA24317228
D003676DeferoxamineDeferoxamine results in decreased expression of CCNA2 protein11468187
D013759DronabinolDronabinol affects the expression of CCNA2 mRNA18454173
D013759DronabinolDronabinol results in decreased expression of CCNA2 mRNA17934890
D013759DronabinolDronabinol results in decreased expression of CCNA2 protein17934890
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of CCNA2 mRNA]27941970
D003907DexamethasoneDexamethasone results in increased expression of CCNA2 mRNA23137833
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNA2 mRNA28628672
D003907Dexamethasone[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein25559859
D003907DexamethasoneDexamethasone results in decreased expression of CCNA2 mRNA21041162
D003907Dexamethasonesilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein]25559859
C539263di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone"di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone affects the expression of CCNA2 protein"21750178
C023614dibenzofurandibenzofuran analog results in decreased expression of CCNA2 mRNA20566336
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CCNA2 mRNA23242528
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of CCNA2 mRNA28962523
D002945Cisplatin[Cisplatin co-treated with Quercetin] results in increased expression of CCNA2 mRNA27514524
D002945CisplatinCisplatin promotes the reaction [Piroxicam results in decreased expression of CCNA2 mRNA]21858171
D002945CisplatinCisplatin results in decreased activity of [CCNA2 protein binds to CDK2 protein]21592546
D002945CisplatinCisplatin results in increased activity of [CDK2 protein binds to CCNA2 protein]12012012
D002945CisplatinTretinoin affects the reaction [Cisplatin results in increased activity of [CDK2 protein binds to CCNA2 protein]]12012012
D002945CisplatinCisplatin results in increased expression of CCNA2 mRNA21151649
D002945CisplatinCisplatin results in decreased expression of CCNA2 mRNA22023808
D019259LamivudineLamivudine results in decreased expression of CCNA2 mRNA15784690
D019259Lamivudine[Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA15784690
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of CCNA2 mRNA25701202
C014476diethyl maleatediethyl maleate results in increased expression of CCNA2 mRNA21161181
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CCNA2 mRNA17854601|2453584
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CCNA2 protein17854601
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 mRNA]17854601
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 protein]17854601
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNA2 mRNA18164116
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CCNA2 mRNA19638242
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNA2 mRNA22129741
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of CCNA2 mRNA21041162
C011612diethyl sulfatediethyl sulfate results in increased expression of CCNA2 protein20566339
C011612diethyl sulfatediethyl sulfate affects the expression of CCNA2 protein23887207
D002117CalcitriolCalcitriol promotes the reaction [Testosterone results in increased expression of CCNA2 mRNA]21592394
D002117CalcitriolCalcitriol results in decreased expression of CCNA2 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of CCNA2 mRNA21592394
D002117CalcitriolTestosterone promotes the reaction [Calcitriol results in increased expression of CCNA2 mRNA]21592394
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CCNA2 mRNA25380136
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CCNA2 protein16155410
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of CCNA2 mRNA22302311
D004147DioxinsDioxins affects the expression of CCNA2 mRNA20463971
D004221Disulfiram[Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein15367699
D017292DoxazosinDoxazosin results in decreased expression of CCNA2 protein15371785
D004317DoxorubicinDoxorubicin affects the expression of and affects the localization of CCNA2 protein17390037
D004317DoxorubicinDoxorubicin affects the expression of CCNA2 protein16036217
D004317DoxorubicinDoxorubicin promotes the reaction [RBL2 protein binds to CCNA2 promoter]16537896
D004317DoxorubicinDoxorubicin results in decreased expression of CCNA2 mRNA15205334
D004317DoxorubicinDoxorubicin results in increased expression of CCNA216284694
D004317DoxorubicinDoxorubicin results in increased expression of CCNA2 protein22751436
D004317Doxorubicinpalbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]22751436
D004317DoxorubicinRB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]]22751436
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of CCNA2 protein"21457722
D004391DustDust results in decreased expression of CCNA2 mRNA17805423
C118739entinostat[fludarabine co-treated with entinostat] results in decreased expression of CCNA2 protein15059916
D060754EquolEquol results in decreased expression of CCNA2 mRNA16865672
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of CCNA2 mRNA24412560
D004918Erythromycin EstolateErythromycin Estolate results in increased expression of CCNA2 mRNA24412560
C007633estragoleestragole results in increased expression of CCNA2 mRNA29054680
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CCNA2 mRNA17942748
D005047EtoposideEtoposide affects the expression of and affects the localization of CCNA2 protein17390037
D005047EtoposideEtoposide results in decreased expression of CCNA2 mRNA16120219
D005047EtoposideEtoposide results in decreased expression of CCNA2 protein16120219
D000068338EverolimusEverolimus results in decreased expression of CCNA2 protein16856892
C017875fisetinfisetin results in decreased expression of CCNA2 protein28181380
C024352fludarabine[fludarabine co-treated with entinostat] results in decreased expression of CCNA2 protein15059916
C012976flumequine"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNA2 mRNA"23681119
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of CCNA2 mRNA28329830
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of CCNA2 protein15158336
D005472FluorouracilCCNA2 protein affects the susceptibility to Fluorouracil15548681|1838381
D005472FluorouracilFluorouracil affects the expression of CCNA2 mRNA16557594
D005472FluorouracilFluorouracil results in decreased expression of CCNA2 mRNA15205334
D005472FluorouracilFluorouracil results in decreased expression of CCNA2 protein15546879
D005472Fluorouracil"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]"15546879
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNA2 protein]15546879
D005472Fluorouracil"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]"15546879
D005473FluoxetineFluoxetine results in decreased expression of CCNA2 mRNA18371935
D005473FluoxetineFluoxetine results in decreased expression of CCNA2 protein18371935
D005492Folic Acid[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNA2 mRNA24657277
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNA2 mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of CCNA2 mRNA23649840
C070081fulvestrant[fulvestrant co-treated with Sirolimus] results in decreased expression of CCNA2 mRNA19016759
C070081fulvestrantfulvestrant promotes the reaction [RB1 protein binds to CCNA2 promoter]21367843
C070081fulvestrantfulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]21367843
C070081fulvestrantfulvestrant results in decreased expression of CCNA2 mRNA15072547|1901675
C070081fulvestrantfulvestrant results in decreased expression of CCNA2 protein21367843
C070081fulvestrantRB1 mutant form inhibits the reaction [fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter]]21367843
C039281furanfuran results in increased expression of CCNA2 mRNA20562052|2207923
D017965gamma-Linolenic Acidgamma-Linolenic Acid results in decreased expression of CCNA2 protein15318936
D019833GenisteinGenistein affects the expression of CCNA2 mRNA18214933
D019833GenisteinGenistein affects the expression of CCNA2 mRNA18847459
D019833GenisteinGenistein results in decreased expression of CCNA221161820
D019833GenisteinGenistein results in decreased expression of CCNA2 mRNA16865672
D019833GenisteinGenistein results in increased expression of CCNA2 mRNA16474171
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein]26577051
C086566glyciteinglycitein results in decreased expression of CCNA221161820
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde affects the expression of CCNA2 mRNA22302311
D017313FenretinideFenretinide results in decreased expression of CCNA2 protein16540676
D017313FenretinideFenretinide results in increased expression of CCNA2 mRNA28973697
C403899HS 1030HS 1030 results in decreased expression of CCNA2 protein15202011
C403900HS 1183HS 1183 results in decreased expression of CCNA2 protein15202011
C503536HS-1199HS-1199 results in decreased expression of CCNA2 protein15202011
C479128HS 1200HS 1200 results in decreased expression of CCNA2 protein15202011
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CCNA2 mRNA23410634
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of CCNA2 mRNA12414654|1241947
C475919hydroxytamoxifenhydroxytamoxifen results in increased expression of CCNA2 mRNA15072547
D006918HydroxyureaHydroxyurea results in increased expression of CCNA2 protein11468187
C492448ICG 001ICG 001 results in decreased expression of CCNA2 mRNA26191083
D000068877Imatinib Mesylate[Imatinib Mesylate co-treated with tetraarsenic tetrasulfide] results in decreased expression of CCNA2 mRNA19208803
D000068877Imatinib MesylateImatinib Mesylate results in decreased expression of CCNA2 mRNA19208803
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNA2 mRNA22129741
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNA2 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCNA2 mRNA25613284
C051890irinotecanirinotecan metabolite results in decreased expression of CCNA2 mRNA15956246
C051890irinotecanirinotecan results in decreased expression of CCNA2 mRNA15956246
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNA2 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein25559859
D0150561-Methyl-3-isobutylxanthinesilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein]25559859
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CCNA2 mRNA24796395|2596192
C561695(+)-JQ1 compound"(+)-JQ1 compound inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [BRD2 protein binds to CCNA2 promoter]]"24319289
C410337K 7174K 7174 results in decreased expression of CCNA2 mRNA24086573
D007649KetamineKetamine results in decreased expression of CCNA2 mRNA20080153
C490728lapatiniblapatinib results in decreased expression of CCNA2 protein25221644
C045463leflunomideleflunomide results in decreased expression of CCNA2 mRNA28988120
C095104LG 100268LG 100268 results in decreased expression of CCNA2 protein15729575
C533894LG 100815LG 100815 results in decreased expression of CCNA2 mRNA16951191
C541528licochalcone Blicochalcone B results in decreased expression of CCNA2 mRNA24384411
D008012LidocaineLidocaine affects the expression of CCNA2 mRNA18931217
C440499lipopolysaccharide, Escherichia coli O111 B4"(+)-JQ1 compound inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [BRD2 protein binds to CCNA2 promoter]]"24319289
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [BRD2 protein binds to CCNA2 promoter]"24319289
D008070LipopolysaccharidesLipopolysaccharides affects the expression of CCNA2 mRNA28070326
D008070LipopolysaccharidesPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of CCNA2 mRNA]28070326
D018021Lithium ChlorideLithium Chloride results in decreased expression of CCNA2 mRNA17440966
D018021Lithium ChlorideLithium Chloride results in decreased expression of CCNA2 protein17440966
D018021Lithium ChlorideLithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]15845746
D008154LucanthoneLucanthone results in decreased expression of CCNA2 mRNA21148553
D047311LuteolinLuteolin results in decreased expression of CCNA2 protein22926442
D008466MechlorethamineMechlorethamine results in decreased activity of [CCNA2 protein binds to CDK2 protein]8463339
D008466MechlorethamineMechlorethamine results in increased expression of and results in increased activity of [CDK2 protein binds to CCNA2 protein]8463339
D008466MechlorethamineMechlorethamine results in increased stability of CCNA2 protein8463339
D008466MechlorethaminePentoxifylline inhibits the reaction [Mechlorethamine results in increased activity of [CCNA2 protein binds to CDK2 protein]]8463339
D008694MethamphetamineMethamphetamine results in decreased expression of CCNA2 mRNA28341135
D008694MethamphetamineMethamphetamine results in decreased expression of CCNA2 protein28341135
D008713MethimazoleMethimazole results in decreased expression of CCNA2 mRNA17403546
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNA2 mRNA20938992
D008727MethotrexateAspirin inhibits the reaction [Methotrexate results in increased expression of CCNA2 protein]23799623
D008727Methotrexate[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNA2 mRNA24657277
D008727MethotrexateMethotrexate results in decreased expression of CCNA2 mRNA24657277
D008727MethotrexateMethotrexate results in increased expression of CCNA2 protein23799623
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CCNA2 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of CCNA2 mRNA20061341
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of CCNA2 protein22101983
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of CCNA2 mRNA16966085
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CCNA2 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CCNA2 mRNA23649840
D008770MethylnitrosoureaMethylnitrosourea results in decreased expression of CCNA215870882
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of CCNA2 mRNA25270620
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of CCNA2 protein18593901
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of CCNA2 mRNA24810058
C008493methylselenic acidmethylselenic acid results in decreased expression of CCNA2 mRNA12517777
C051786metolachlormetolachlor results in decreased expression of CCNA2 mRNA23084262
D015741MetriboloneMetribolone results in increased expression of CCNA2 mRNA19318562
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein]26577051
D015735MifepristoneMifepristone results in decreased expression of CCNA2 protein17545545
C070571ML 7ML 7 inhibits the reaction [EGF protein results in increased expression of CCNA2 protein]16799973
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of CCNA2 mRNA22956148
C047806monomethylpropionmonomethylpropion results in increased expression of CCNA2 mRNA22303338
D009151Mustard GasMustard Gas results in decreased expression of CCNA2 mRNA25102026
C059685N(1),N(11)-diethylnorspermine"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNA2 protein]]"15546879
D019810Sodium AzideSodium Azide inhibits the reaction [ELAVL1 protein binds to CCNA2 3' UTR]12730239
D019810Sodium AzideSodium Azide results in decreased expression of CCNA2 mRNA12730239
D019810Sodium AzideSodium Azide results in decreased expression of CCNA2 protein12730239
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CCNA2 mRNA"15585362
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of CCNA2 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CCNA2 mRNA"25554681
C031721naphthalene[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein28803881
C031721naphthalenenaphthalene results in decreased expression of CCNA2 protein28803881
D009532NickelNickel results in increased expression of CCNA2 mRNA25583101
C017557nickel subsulfidenickel subsulfide results in increased expression of CCNA2 mRNA24952340
D009538NicotineNicotine results in increased expression of CCNA2 protein18448488|2010694
C012655nimesulidenimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein]14966570
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in decreased expression of CCNA2 mRNA22561872
C008661nobiletinnobiletin results in decreased expression of CCNA2 mRNA23321314
C008661nobiletinnobiletin results in decreased expression of CCNA2 mRNA23321314
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of CCNA2 mRNA20971185
C025589ochratoxin Aochratoxin A results in decreased acetylation of CCNA2 promoter29098329
C025589ochratoxin A[ochratoxin A results in decreased acetylation of CCNA2 promoter] which results in decreased expression of CCNA2 mRNA29098329|2909832
C025589ochratoxin Aochratoxin A results in decreased expression of CCNA2 mRNA29098329
C025589ochratoxin Aochratoxin A results in increased expression of CCNA2 mRNA18417182|1923760
C062198octa-2,4,6-trienoic acid"octa-2,4,6-trienoic acid results in decreased expression of CCNA2 mRNA"16951191
C031004oligomycin Aoligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein]24909818
C030110oxaliplatinoxaliplatin results in increased expression of CCNA2 protein15204521
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CCNA2 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of CCNA2 mRNA25729387
D010100OxygenOxygen results in decreased expression of CCNA2 mRNA27103661
D010100OxygenOxygen deficiency results in increased expression of CCNA2 mRNA26476374
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of CCNA2 mRNA]26476374
D010126Ozone[Ozone co-treated with NOTCH3 gene mutant form] results in increased expression of CCNA2 mRNA25658374
D010126OzoneTTPA protein affects the reaction [Ozone results in increased expression of CCNA2 mRNA]19555225
C500026palbociclibE2F2 protein inhibits the reaction [palbociclib results in decreased expression of CCNA2 protein]20100483
C500026palbociclibpalbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]22751436
C500026palbociclibpalbociclib inhibits the reaction [RBL1 protein binds to CCNA2 promoter]20100483
C500026palbociclibpalbociclib promotes the reaction [RB1 protein binds to CCNA2 promoter]21367843
C500026palbociclibpalbociclib results in decreased expression of CCNA2 mRNA20100483|2286955
C500026palbociclibpalbociclib results in decreased expression of CCNA2 protein20100483|2047333
C500026palbociclibRB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of CCNA2 protein]]22751436
C500026palbociclibRB1 protein affects the reaction [palbociclib inhibits the reaction [RBL1 protein binds to CCNA2 promoter]]20100483
C500026palbociclibRB1 protein affects the reaction [palbociclib results in decreased expression of CCNA2 protein]20473330
C500026palbociclibpalbociclib results in decreased expression of CCNA2 mRNA24606660
D010278Parathion[Estradiol co-treated with Parathion] results in decreased expression of CCNA2 mRNA17622325
D010278ParathionParathion results in decreased expression of CCNA2 mRNA17622325
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNA2 mRNA"25510870
C008776pelargonic acidpelargonic acid affects the expression of CCNA2 mRNA22302311
D010431PentoxifyllinePentoxifylline inhibits the reaction [Mechlorethamine results in increased activity of [CCNA2 protein binds to CDK2 protein]]8463339
C494474perchlorateperchlorate results in decreased expression of CCNA2 mRNA17403546
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CCNA2 mRNA23427857
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CCNA2 mRNA17560707
C031181phenanthrene[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein28803881
C031181phenanthrenephenanthrene results in decreased expression of CCNA2 protein28803881
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of CCNA2 protein26678675
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of CCNA2 mRNA]19482888
D010634Phenobarbital[Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA23626729
D010634PhenobarbitalPhenobarbital results in increased expression of CCNA2 mRNA19363144|1948288
D010634PhenobarbitalPhenobarbital results in decreased expression of CCNA2 mRNA22008536
D019800PhenolPhenol results in decreased expression of CCNA2 protein19293009
D009764o-Phthalaldehydeo-Phthalaldehyde affects the expression of CCNA2 mRNA22302311
D048789PhytoestrogensPhytoestrogens results in increased expression of CCNA2 mRNA18310284
C049032pinosylvinpinosylvin results in decreased expression of CCNA2 protein23333577
C060836pioglitazonepioglitazone results in decreased expression of CCNA2 protein15729575
C006253pirinixic acid[pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA23626729
C006253pirinixic acidpirinixic acid results in decreased expression of CCNA2 mRNA17426115
C006253pirinixic acidpirinixic acid results in increased expression of CCNA2 mRNA17950772|1830175
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in increased expression of CCNA2 mRNA]17950772
C006253pirinixic acidRXRA protein promotes the reaction [pirinixic acid results in increased expression of CCNA2 mRNA]19176532
D010894PiroxicamCisplatin promotes the reaction [Piroxicam results in decreased expression of CCNA2 mRNA]21858171
D010894PiroxicamPiroxicam results in decreased expression of CCNA2 mRNA21858171
D010936Plant ExtractsPlant Extracts affects the reaction [Lipopolysaccharides affects the expression of CCNA2 mRNA]28070326
D010936Plant ExtractsPlant Extracts results in decreased expression of CCNA2 protein15327971|2612252
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog results in increased expression of CCNA2 mRNA16474171
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in decreased expression of CCNA2 mRNA24583197
D011192Potassium DichromatePotassium Dichromate results in increased expression of CCNA2 protein23718831
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CCNA2 mRNA26348139
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CCNA2 protein26348139
D011285Pregnenolone Carbonitrile"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA"23626729
D011285Pregnenolone Carbonitrile[Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA23626729
D011285Pregnenolone Carbonitrile[pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA23626729
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of CCNA2 mRNA19693291
D011374ProgesteroneLithium Chloride inhibits the reaction [Progesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]]15845746
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased expression of CCNA2 protein]15845746
C045950propiconazolepropiconazole results in increased expression of CCNA2 mRNA21278054
C005556propionaldehydepropionaldehyde results in decreased expression of CCNA2 mRNA26079696
C006068propylparaben[propylparaben co-treated with Butylated Hydroxyanisole] results in decreased expression of CCNA2 mRNA25086368
C006068propylparabenpropylparaben results in decreased expression of CCNA2 mRNA25086368
D011441PropylthiouracilPropylthiouracil results in increased expression of CCNA2 mRNA24780913
D011441PropylthiouracilPropylthiouracil results in decreased expression of CCNA2 mRNA17403546
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of CCNA2 mRNA"21152443
C030984pyrene[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] results in decreased expression of CCNA2 protein28803881
C030984pyrenepyrene results in decreased expression of CCNA2 protein28803881
D011743PyrimidinesPyrimidines affects the splicing of CCNA2 mRNA25281741
D011791QuartzQuartz results in increased expression of CCNA2 mRNA19836432
D011794Quercetin[Cisplatin co-treated with Quercetin] results in increased expression of CCNA2 mRNA27514524
D011794QuercetinQuercetin results in decreased expression of CCNA2 mRNA21632981
D011794QuercetinQuercetin results in decreased expression of CCNA2 protein20803121|2529387
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of CCNA2 mRNA]26476374
D011799QuinazolinesQuinazolines affects the splicing of CCNA2 mRNA25281741
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of CCNA2 mRNA17445807
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of CCNA2 protein17445807
C059514resveratrolresveratrol metabolite results in increased expression of CCNA2 mRNA19496085
C059514resveratrolresveratrol results in decreased expression of CCNA2 mRNA15767336|1808983
C059514resveratrolresveratrol results in decreased expression of CCNA2 protein11895924|1676196
C059514resveratrolresveratrol results in increased expression of CCNA215583814
C059514resveratrolresveratrol results in increased expression of CCNA2 protein11481417|1150706
C059514resveratrolresveratrol results in decreased expression of CCNA2 mRNA23525482|2433039
C059514resveratrolresveratrol results in decreased expression of CCNA2 protein22935344|2352548
C059514resveratrolresveratrol results in decreased expression of CCNA2 protein20972827
C547185riccardin Driccardin D results in decreased expression of CCNA2 mRNA24069304
C547185riccardin Driccardin D results in decreased expression of CCNA2 protein24069304
D019438RitonavirRitonavir results in decreased expression of CCNA2 mRNA19386116
C087123romidepsinromidepsin results in decreased expression of CCNA2 protein15014036
C104586roscovitineroscovitine results in decreased expression of CCNA2 protein20100483|2141741
C089730rosiglitazonerosiglitazone results in decreased expression of CCNA2 protein15729575
C064116S-(1,1,2,2-tetrafluoroethyl)cysteine"S-(1,1,2,2-tetrafluoroethyl)cysteine results in decreased expression of CCNA2 mRNA"16678137
C002979selenomethylselenocysteineselenomethylselenocysteine results in decreased expression of CCNA2 protein11396176
C078903seocalcitolseocalcitol results in decreased expression of CCNA2 mRNA12040012
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CCNA2 mRNA23806026
D012835Silver NitrateSilver Nitrate analog results in decreased expression of CCNA2 mRNA22831968
C440975silybinsilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein]25559859
D019821SimvastatinSimvastatin results in decreased expression of CCNA2 mRNA17428261
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein]26577051
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein]26577051
D019821SimvastatinSimvastatin results in decreased expression of CCNA2 protein26577051
D020123Sirolimus[fulvestrant co-treated with Sirolimus] results in decreased expression of CCNA2 mRNA19016759
D020123SirolimusSirolimus results in decreased expression of CCNA28419408
D020123SirolimusSirolimus results in decreased expression of CCNA2 protein19505958
D020123SirolimusSirolimus results in decreased expression of CCNA2 protein7503980
C017947sodium arsenitesodium arsenite results in increased expression of CCNA2 mRNA17879257
C017947sodium arsenitesodium arsenite inhibits the reaction [PDK4 gene mutant form results in increased expression of CCNA2 protein]28003426
C017947sodium arsenitesodium arsenite results in decreased expression of CCNA2 mRNA16014739
C017947sodium arsenitesodium arsenite results in decreased expression of CCNA2 protein20336670
D018038Sodium SeleniteSodium Selenite results in decreased expression of CCNA2 mRNA24383545
D012999SomanSoman results in increased expression of CCNA2 mRNA19281266
D053260SootSoot results in increased expression of CCNA2 mRNA22461453|2655175
C471405sorafenibsorafenib results in decreased expression of CCNA2 protein19139124
C075117squalestatin 1squalestatin 1 results in decreased expression of CCNA2 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of CCNA2 mRNA27225895
D010042OuabainOuabain results in decreased expression of CCNA2 mRNA21215801
D013467SulindacSulindac results in decreased expression of CCNA2 protein16488075
D014284TriiodothyronineTriiodothyronine results in increased expression of CCNA2 protein16021636
D014284TriiodothyronineTriiodothyronine results in increased expression of CCNA2 protein16021636
C112689TAC 101TAC 101 results in decreased expression of CCNA2 protein10225456
D013629Tamoxifen[Estradiol co-treated with Tamoxifen] results in decreased expression of CCNA2 mRNA19434490
D013629TamoxifenTamoxifen results in increased expression of CCNA2 protein15642790
D013739TestosteroneCalcitriol promotes the reaction [Testosterone results in increased expression of CCNA2 mRNA]21592394
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of CCNA2 mRNA21592394
D013739TestosteroneTestosterone promotes the reaction [Calcitriol results in increased expression of CCNA2 mRNA]21592394
D013739TestosteroneTestosterone results in decreased expression of CCNA2 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of CCNA2 mRNA19693291
C534735tetraarsenic tetrasulfide[Imatinib Mesylate co-treated with tetraarsenic tetrasulfide] results in decreased expression of CCNA2 mRNA19208803
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNA2 mRNA16714409
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CCNA2 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNA2 mRNA27913140
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CCNA2 mRNA21802500
D013749Tetrachlorodibenzodioxin2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCNA2 protein]24013123
D013749Tetrachlorodibenzodioxin3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CCNA2 protein]24013123
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CCNA2 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNA2 mRNA]11861973
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein]]"20637255
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1A protein]]"20637255
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1A protein]]] which results in decreased activity of CDK2 protein"20637255
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1B protein]]"20637255
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK2 protein binds to CCNA2 protein binds to CDKN1B protein]]] which results in decreased activity of CDK2 protein"20637255
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNA2 protein]"20637255
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNA2 mRNA16120747
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNA2 protein24013123
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CCNA2 mRNA15667827|1977048
D013749TetrachlorodibenzodioxinAHR affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CCNA2 protein]17141280
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TNF protein] results in increased expression of CCNA2 mRNA17557910
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [CCNA2 protein binds to CDK2 protein]12387751
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of [CCNA2 protein binds to CDK2 protein]12387751|1714128
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased localization of CCNA2 protein12387751
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CCNA2 protein15592923|1714128
D013755Tetradecanoylphorbol Acetate"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]"12421932
D013755Tetradecanoylphorbol AcetateIL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]12421932
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in decreased expression of CCNA2 protein15949478
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of CCNA2 mRNA19031421
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of CCNA2 protein12421932
D013755Tetradecanoylphorbol AcetateTretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]12421932
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCNA2 mRNA25613284
D013792Thalidomide[Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA18720364
D019284ThapsigarginThapsigargin results in decreased expression of CCNA2 mRNA22378314
D013853ThioacetamideThioacetamide results in increased expression of CCNA2 mRNA22659510|2341159
D013974ThyroxineThyroxine affects the expression of CCNA2 mRNA17403546
C009495titanium dioxide[Vitallium analog binds to titanium dioxide] which results in decreased expression of CCNA2 mRNA23825117
C009495titanium dioxidetitanium dioxide results in increased expression of CCNA2 mRNA23557971
D014028Tobacco Smoke PollutionNFE2L2 protein promotes the reaction [Tobacco Smoke Pollution affects the expression of CCNA2 mRNA]20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CCNA2 mRNA20133372
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CCNA2 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of CCNA2 mRNA25729387
C099150trabectedintrabectedin results in decreased expression of CCNA2 mRNA15961672
D014212TretinoinTretinoin affects the reaction [Cisplatin results in increased activity of [CDK2 protein binds to CCNA2 protein]]12012012
D014212TretinoinTretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased expression of CCNA2 protein]11348869
D014212TretinoinTretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]12421932
D014212TretinoinTretinoin results in decreased expression of CCNA2 mRNA17138961
D014212TretinoinTretinoin results in decreased expression of CCNA2 protein16517207
D014212TretinoinTretinoin results in increased expression of CCNA2 mRNA17198874
D014212TretinoinTretinoin results in increased expression of CCNA2 protein15231690
D014241TrichloroethyleneTrichloroethylene results in increased expression of CCNA2 mRNA25549359
C012589trichostatin Atrichostatin A results in decreased expression of CCNA2 mRNA15901671
C012589trichostatin Atrichostatin A affects the expression of CCNA2 mRNA28542535
C012589trichostatin Atrichostatin A results in decreased expression of CCNA2 protein15179185
C015559trimellitic anhydridetrimellitic anhydride affects the expression of CCNA2 mRNA22302311
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of CCNA2 mRNA19042947
C001899triptolidetriptolide results in increased expression of CCNA2 mRNA23639586
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of CCNA2 mRNA"26179874
C057693troglitazonetroglitazone results in decreased expression of CCNA2 mRNA19140230
C057693troglitazonetroglitazone results in decreased expression of CCNA2 protein15729575
D014415TunicamycinTunicamycin results in decreased expression of CCNA2 mRNA22378314
C004218tylophorinetylophorine analog results in decreased expression of CCNA219284764
D014635Valproic AcidValproic Acid results in decreased expression of CCNA2 mRNA15901671
D014635Valproic AcidValproic Acid results in decreased expression of CCNA2 mRNA23179753|2637803
D014638Vanadates2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased expression of CCNA2 protein]14971663
D014638VanadatesVanadates results in increased expression of CCNA2 protein14971663
D014638Vanadateswortmannin inhibits the reaction [Vanadates results in increased expression of CCNA2 protein]14971663
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of CCNA2 gene25560391
C029297vinylidene chloridevinylidene chloride results in increased expression of CCNA2 mRNA26682919
D014800Vitallium[Vitallium analog binds to titanium dioxide] which results in decreased expression of CCNA2 mRNA23825117
D014800VitalliumVitallium analog results in decreased expression of CCNA2 mRNA23825117
D024483Vitamin K 3Vitamin K 3 affects the expression of CCNA2 mRNA23410634
D024483Vitamin K 3Vitamin K 3 results in decreased expression of CCNA2 mRNA12414654
C111237vorinostatvorinostat results in decreased expression of CCNA2 protein19875160
C085514wogoninwogonin results in decreased expression of CCNA2 protein21457722
C009687wortmanninwortmannin inhibits the reaction [Vanadates results in increased expression of CCNA2 protein]14971663
C118180XK 469XK 469 results in increased expression of CCNA2 protein11774253
D015215Zidovudine[Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNA2 mRNA20370541
D015215Zidovudine[Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA15784690
D015215ZidovudineZidovudine results in decreased expression of CCNA2 mRNA15784690
D015032ZincZinc deficiency results in increased expression of CCNA2 mRNA22171008
C088658zoledronic acidzoledronic acid results in decreased expression of CCNA2 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004672protein kinase activityCONTRIBUTES_TOIBA21873635  
GO:0005515protein binding-IPI7630397  8411358  8684460  8756328  12244298  12941338  
15189033  15239650  15890360  16061792  16209941  17254966  
20596027  21952639  22810586  23455922  23602568  24358021  
24670654  25852190  26496610  
GO:0016538cyclin-dependent protein serine/threonine kinase regulator activity-IBA21873635  
GO:0019901protein kinase binding-IBA21873635  
GO:0019901protein kinase binding-IPI1312467  15024385  
GO:0019904protein domain specific binding-IPI15024385  
GO:0097472cyclin-dependent protein kinase activitycontributes_toIDA1312467  
GO ID GO Term Qualifier Evidence PubMed
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity-IBA21873635  
GO:0000086G2/M transition of mitotic cell cycle-IBA21873635  
GO:0000086G2/M transition of mitotic cell cycle-IDA1312467  
GO:0000278mitotic cell cycle-IBA21873635  
GO:0007088regulation of mitotic nuclear division-IBA21873635  
GO:0007265Ras protein signal transduction-IEP9054499  
GO:0008284positive regulation of cell proliferation-IBA21873635  
GO:0016032viral process-IEA-  
GO:0016572histone phosphorylation-IDA11746698  
GO:0016579protein deubiquitination-TAS-  
GO:0031100animal organ regeneration-IEA-  
GO:0033762response to glucagon-IEA-  
GO:0036120cellular response to platelet-derived growth factor stimulus-IEA-  
GO:0044320cellular response to leptin stimulus-IEA-  
GO:0044843cell cycle G1/S phase transition-IDA1312467  
GO:0045787positive regulation of cell cycle-IBA21873635  
GO:0045893positive regulation of transcription, DNA-templated-IEA-  
GO:0048146positive regulation of fibroblast proliferation-IEA-  
GO:0051301cell division-IEA-  
GO:0051726regulation of cell cycle-IEA-  
GO:0071314cellular response to cocaine-IEA-  
GO:0071373cellular response to luteinizing hormone stimulus-IEA-  
GO:0071392cellular response to estradiol stimulus-IEA-  
GO:0071456cellular response to hypoxia-IEA-  
GO:0071732cellular response to nitric oxide-IEA-  
GO:0090102cochlea development-IEA-  
GO:1990314cellular response to insulin-like growth factor stimulus-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000307cyclin-dependent protein kinase holoenzyme complex-IBA21873635  
GO:0000307cyclin-dependent protein kinase holoenzyme complex-IDA1312467  
GO:0001939female pronucleus-IEA-  
GO:0001940male pronucleus-IEA-  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA1312467  16109376  
GO:0005654nucleoplasm-IDA8245034  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA1312467  23791195  
GO:0005829cytosol-IDA-  
GO:0097124cyclin A2-CDK2 complex-IBA21873635  
GO:0097124cyclin A2-CDK2 complex-IDA1312467  11746698  15024385  
KEGG ID KEGG Term
hsa04110Cell cycle
hsa04914Progesterone-mediated oocyte maturation
Reactome ID Reactome Term Evidence
R-HSA-1362300Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1IEA
R-HSA-1538133G0 and Early G1TAS
R-HSA-1538133G0 and Early G1IEA
R-HSA-1640170Cell CycleTAS
R-HSA-1640170Cell CycleIEA
R-HSA-170145Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexesTAS
R-HSA-174143APC/C-mediated degradation of cell cycle proteinsTAS
R-HSA-174184Cdc20:Phospho-APC/C mediated degradation of Cyclin ATAS
R-HSA-176408Regulation of APC/C activators between G1/S and early anaphaseTAS
R-HSA-176409APC/C:Cdc20 mediated degradation of mitotic proteinsTAS
R-HSA-176814Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsTAS
R-HSA-179419APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpointTAS
R-HSA-187577SCF(Skp2)-mediated degradation of p27/p21TAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559582Senescence-Associated Secretory Phenotype (SASP)TAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-2559586DNA Damage/Telomere Stress Induced SenescenceTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-453274Mitotic G2-G2/M phasesTAS
R-HSA-453274Mitotic G2-G2/M phasesIEA
R-HSA-453276Regulation of mitotic cell cycleTAS
R-HSA-453279Mitotic G1-G1/S phasesTAS
R-HSA-453279Mitotic G1-G1/S phasesIEA
R-HSA-5633007Regulation of TP53 ActivityTAS
R-HSA-5688426DeubiquitinationTAS
R-HSA-5689880Ub-specific processing proteasesTAS
R-HSA-5693532DNA Double-Strand Break RepairTAS
R-HSA-5693538Homology Directed RepairTAS
R-HSA-5693567HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)TAS
R-HSA-5693607Processing of DNA double-strand break endsTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6791312TP53 Regulates Transcription of Cell Cycle GenesTAS
R-HSA-6804116TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle ArrestTAS
R-HSA-6804756Regulation of TP53 Activity through PhosphorylationTAS
R-HSA-6804757Regulation of TP53 DegradationTAS
R-HSA-6806003Regulation of TP53 Expression and DegradationTAS
R-HSA-68911G2 PhaseTAS
R-HSA-68949Orc1 removal from chromatinTAS
R-HSA-69017CDK-mediated phosphorylation and removal of Cdc6TAS
R-HSA-69052Switching of origins to a post-replicative stateTAS
R-HSA-69202Cyclin E associated events during G1/S transition TAS
R-HSA-69206G1/S TransitionTAS
R-HSA-69239Synthesis of DNATAS
R-HSA-69242S PhaseTAS
R-HSA-69273Cyclin A/B1/B2 associated events during G2/M transitionTAS
R-HSA-69273Cyclin A/B1/B2 associated events during G2/M transitionIEA
R-HSA-69275G2/M TransitionTAS
R-HSA-69275G2/M TransitionIEA
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-69306DNA ReplicationTAS
R-HSA-69563p53-Dependent G1 DNA Damage ResponseTAS
R-HSA-69580p53-Dependent G1/S DNA damage checkpointTAS
R-HSA-69615G1/S DNA Damage CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsTAS
R-HSA-69656Cyclin A:Cdk2-associated events at S phase entryTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73894DNA RepairTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8953897Cellular responses to external stimuliTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26439031Identification of potential therapeutic target genes and mechanisms in non-small-cell lung carcinoma in non-smoking women based on bioinformatics analysis. (2015 Sep)Zhou WEur Rev Med Pharmacol Sci