Gene: CCNB1

891
CCNB
cyclin B1
protein-coding
5q13.2
Ensembl:ENSG00000134057 MIM:123836 Vega:OTTHUMG00000097817 UniprotKB:P14635
NC_000005.10
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.418e-1 (AD)  6.163e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC25A140.931
TMEM2460.928
PABPC1L2B0.925
FBXL20.923
GLRB0.923
MAP2K40.922
ELOVL40.921
GLS0.92
PCSK20.92
MCF20.919

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ASB4-0.542
YES1-0.534
HEY2-0.513
RAI14-0.51
REST-0.509
MYL3-0.507
MBNL3-0.5
MAPKAPK3-0.493
PARD3B-0.492
COPZ2-0.49

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of CCNB1 mRNA"26377693
C478160(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane"(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]"20195699
C478160(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane"[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 mRNA"28757135
C478160(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane"[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 protein"28757135
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in decreased expression of CCNB1 protein"21903591|2382612
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"acetyl-valyl-isoleucyl-aspartyl-aldehyde inhibits the reaction [1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in decreased expression of CCNB1 protein]"21903591
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA"23626729
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNB1 mRNA"28903501
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNB1 protein"15382178
C0252231,4-dioxane"1,4-dioxane results in increased expression of CCNB1 protein"20025956
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNB1 protein"15729575
C07258116-hydroxycleroda-3,13(14)-dien-15,16-olide"16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased expression of CCNB1 protein"21530604
C00743317,20-dihydroxy-4-pregnen-3-one"17,20-dihydroxy-4-pregnen-3-one results in increased expression of CCNB1 protein"16336677
C495172(19Z)-halichondramide(19Z)-halichondramide results in decreased expression of CCNB1 protein23147639
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with Doxorubicin] results in decreased expression of CCNB1 protein"20826841
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased expression of CCNB1 protein"20826841
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CCNB1 mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CCNB1 mRNA"26988655
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CCNB1 mRNA"20566336
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein]19038232
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C4881852-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide"[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein]"26385184
C4881852-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide"[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CCNB1 protein]"26385184
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNB1 mRNA"19167446
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of CCNB1 mRNA"15201435
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CCNB1 protein"16120219
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in increased expression of CCNB1 mRNA25088246
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNB1 mRNA"23681119
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of CCNB1 protein20469912
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of CCNB1 protein20469912
C0702792'-cyano-2'-deoxyarabinofuranosylcytosine2'-cyano-2'-deoxyarabinofuranosylcytosine results in increased expression of CCNB1 protein16061671
C518368(2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide"(2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide results in decreased expression of CCNB1"17352252
C5452392'-epi-2'-O-acetylthevetin B2'-epi-2'-O-acetylthevetin B results in decreased expression of CCNB1 protein19874809
C1202752-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNB1 protein11468187
C0228302-methoxyestradiol2-methoxyestradiol results in increased expression of and results in increased activity of CCNB1 protein16356831
C0228302-methoxyestradiol2-methoxyestradiol results in increased expression of CCNB1 protein23967052
C5264382-methoxyestradiol-3,17-O,O-bis(sulfamate)"2-methoxyestradiol-3,17-O,O-bis(sulfamate) results in increased expression of CCNB1 protein"18223236
C0194992-nitrofluorene2-nitrofluorene results in increased expression of CCNB1 mRNA15890375
C0841792-phenyl-4-oxohydroquinoline2-phenyl-4-oxohydroquinoline analog affects the expression of CCNB1 protein27769712
C5467063-(3,4,5-trimethoxybenzylidene)-5-carboethoxyindolin-2-one"3-(3,4,5-trimethoxybenzylidene)-5-carboethoxyindolin-2-one results in increased expression of CCNB1 protein"19883635
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased expression of CCNB1"22290291
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCNB1 mRNA"23196670
C5277933-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane"3-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane results in increased expression of CCNB1 protein"18176113
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in decreased expression of CCNB1 protein"26138072
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenite results in increased ubiquitination of and results in increased degradation of CCNB1 protein]17373649
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CCNB1 protein]20067818
C4747224-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [N'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazide results in increased expression of CCNB1 protein]24748653
C4747224-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]24748653
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide inhibits the reaction [arsenic trioxide results in decreased expression of CCNB1 mRNA]"25499136
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide inhibits the reaction [arsenic trioxide results in decreased expression of CCNB1 protein]"25499136
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CCNB1 mRNA19191707
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCNB1 mRNA15890375
C0415944-nonylphenol4-nonylphenol results in increased expression of CCNB1 protein26804764
C5036435-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin"5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin results in increased expression of CCNB1 protein"16179969
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased expression of CCNB1 protein16179969
C5497535,7,3'-trihydroxy-3,4'-dimethoxyflavone"5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CCNB1 protein"21229608
C5497535,7,3'-trihydroxy-3,4'-dimethoxyflavone"5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CCNB1 protein"21229608
C5805985-OH-BDE-475-OH-BDE-47 results in increased expression of CCNB1 mRNA26988655
C5762686-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide"6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased expression of CCNB1 protein"27720946
C5715326-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased expression of CCNB1 protein25316768
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in decreased expression of CCNB1 protein"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in decreased expression of CCNB1 protein]"23274516
C5838836-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone"6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone results in increased expression of CCNB1 protein"23212307
C5838836-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone"pyrazolanthrone inhibits the reaction [6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone results in increased expression of CCNB1 protein]"23212307
C5805996-OH-BDE-476-OH-BDE-47 results in increased expression of CCNB1 mRNA26988655
C1217077,3'-dihydroxy-4'-methoxyisoflavone"7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CCNB1 mRNA"24455688
C0257249-methoxycamptothecin9-methoxycamptothecin results in increased expression of CCNB1 mRNA23369935
D000082AcetaminophenAcetaminophen results in increased expression of CCNB1 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of CCNB1 mRNA17562736
D000082AcetaminophenAcetaminophen results in decreased expression of CCNB1 mRNA17942131
D000082AcetaminophenAcetaminophen results in increased expression of CCNB1 protein20025956
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CCNB1 protein]28548367
D000111AcetylcysteineAcetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]24909818
D000111AcetylcysteineAcetylcysteine inhibits the reaction [erythritol anhydride results in increased expression of CCNB1 protein]25633853
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal inhibits the reaction [arsenite results in increased degradation of CCNB1 protein]17373649
C110923acetyl-valyl-isoleucyl-aspartyl-aldehyde"acetyl-valyl-isoleucyl-aspartyl-aldehyde inhibits the reaction [1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in decreased expression of CCNB1 protein]"21903591
D020106AcrylamideAcrylamide results in increased expression of CCNB1 protein20025956
D020106AcrylamideAcrylamide results in increased expression of CCNB1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of CCNB1 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CCNB1 mRNA19770486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CCNB1 mRNA15890375
C430898AGN 194204AGN 194204 results in decreased expression of CCNB1 protein15318936
C031143AICA ribonucleotideAICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]12730239
C031143AICA ribonucleotideAICA ribonucleotide results in decreased expression of CCNB1 mRNA12730239
C031143AICA ribonucleotideAICA ribonucleotide results in decreased expression of CCNB1 protein12730239
C000188alachloralachlor results in increased expression of CCNB1 mRNA12419858
D000452AldrinAldrin results in increased expression of CCNB1 mRNA18579281
C038491allyl sulfideallyl sulfide results in decreased expression of CCNB1 mRNA24650757
C038491allyl sulfideallyl sulfide results in decreased expression of CCNB1 protein24650757
C038491allyl sulfideCHEK1 protein promotes the reaction [allyl sulfide results in decreased expression of CCNB1 protein]24650757
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of CCNB1 mRNA17023530
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA]25051199
C077990alvocidib[alvocidib co-treated with PBOX-6] results in decreased expression of CCNB1 protein20206141
C077990alvocidibalvocidib inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]10430095
C077990alvocidibalvocidib results in decreased expression of and results in decreased activity of CCNB1 protein16731754
C077990alvocidibalvocidib results in decreased expression of CCNB1 protein12517783|1501403
D000584AmilorideAmiloride results in decreased expression of CCNB1 protein9458082
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CCNB1 mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CCNB1 protein16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of CCNB1 mRNA"22863853
D000677AmsacrineAmsacrine results in increased degradation of and results in decreased expression of CCNB1 protein11774253
D000872AnthocyaninsAnthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]27444805
D000872AnthocyaninsAnthocyanins results in increased expression of CCNB1 protein27444805
D000968Antimycin AAntimycin A inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]12730239
D000968Antimycin AAntimycin A results in decreased expression of CCNB1 mRNA12730239
D000968Antimycin AAntimycin A results in decreased expression of CCNB1 protein12730239
C102351apicidinapicidin results in decreased expression of CCNB1 mRNA19070610
D047310ApigeninApigenin results in decreased expression of CCNB1 mRNA19397994
D047310ApigeninApigenin results in decreased expression of CCNB1 protein19397994|2696160
C519728archazolid Barchazolid B results in decreased expression of CCNB1 mRNA25218289
C000228aristolochic acid Iaristolochic acid I results in decreased expression of CCNB1 mRNA17483316
D034341Aristolochic AcidsAristolochic Acids results in increased expression of CCNB1 mRNA19717638
D001149Arsenates[Atrazine co-treated with Arsenates] results in increased expression of CCNB1 mRNA18585445
D001151ArsenicArsenic results in increased expression of CCNB125868784
D001151Arsenicsilybin inhibits the reaction [Arsenic results in increased expression of CCNB1]25868784
C058317arsenic disulfidearsenic disulfide results in increased expression of CCNB1 mRNA12890387
C006632arsenic trioxide"4-amino-1,8-naphthalimide inhibits the reaction [arsenic trioxide results in decreased expression of CCNB1 mRNA]"25499136
C006632arsenic trioxide"4-amino-1,8-naphthalimide inhibits the reaction [arsenic trioxide results in decreased expression of CCNB1 protein]"25499136
C006632arsenic trioxide[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 mRNA19825857
C006632arsenic trioxide[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 protein19825857
C006632arsenic trioxidearsenic trioxide results in decreased expression of CCNB1 mRNA17530438|1982585
C006632arsenic trioxidearsenic trioxide results in decreased expression of CCNB1 protein12883267|1982585
C006632arsenic trioxidearsenic trioxide results in increased expression of CCNB1 mRNA12783709|2045855
C006632arsenic trioxidearsenic trioxide results in increased expression of CCNB1 protein12181429
C006632arsenic trioxidearsenic trioxide results in increased expression of CCNB1 protein23337567
C015001arsenite4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenite results in increased ubiquitination of and results in increased degradation of CCNB1 protein]17373649
C015001arseniteacetylleucyl-leucyl-norleucinal inhibits the reaction [arsenite results in increased degradation of CCNB1 protein]17373649
C015001arsenitearsenite results in decreased expression of and results in increased degradation of CCNB1 protein17373649
C015001arsenitearsenite results in decreased expression of CCNB1 protein20083129
C015001arsenitearsenite results in increased ubiquitination of CCNB1 protein17373649
C015001arsenitebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [arsenite results in increased ubiquitination of CCNB1 protein]17373649
C015001arseniteMAPK14 mutant form inhibits the reaction [arsenite results in increased ubiquitination of and results in increased degradation of CCNB1 protein]17373649
C015001arsenitearsenite results in decreased expression of CCNB1 mRNA18929588
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CCNB1 mRNA"25351596
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein]21621607
D001241AspirinAspirin inhibits the reaction [troglitazone results in decreased expression of CCNB1 protein]19908241
D001241AspirinAspirin results in increased expression of CCNB1 mRNA11906190
D001280AtrazineAtrazine results in increased expression of CCNB1 mRNA25929836
D001280Atrazine[Atrazine co-treated with Arsenates] results in increased expression of CCNB1 mRNA18585445
D001374Azacitidine[Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA18720364
D001374AzacitidineAzacitidine results in decreased expression of CCNB1 protein15547111
D001374AzacitidineAzacitidine results in increased expression of CCNB1 protein20607034
D001374Azacitidinepifithrin inhibits the reaction [Azacitidine results in decreased expression of CCNB1 protein]15547111
D001379AzathioprineAzathioprine results in decreased expression of CCNB1 mRNA22623647
C517975AZD 6244AZD 6244 results in decreased expression of CCNB1 protein17876044
C517975AZD 6244Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CCNB1 protein]17876044
C006680baicaleinbaicalein results in decreased expression of CCNB1 protein18025287
C487081belinostatbelinostat results in decreased expression of CCNB1 mRNA19606018
D001542BenomylCCNB1 protein results in increased susceptibility to Benomyl11960377
D001554BenzeneBenzene analog results in increased expression of CCNB1 protein15826604
D001554BenzeneTRP53 protein promotes the reaction [Benzene results in decreased expression of CCNB1]15935813
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CCNB1 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNA18164116
C047723benzophenonebenzophenone results in increased expression of CCNB1 mRNA22584684
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNB1 mRNA16120219|2006483
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNB1 protein16120219
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased degradation of and results in decreased expression of CCNB1 protein29126329
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CCNB1 mRNA17942131|2222880
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CCNB1 mRNA"19150397|2001819
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [arsenite results in increased ubiquitination of CCNB1 protein]17373649
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB1 mRNA20061341
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA25566086
D004958EstradiolEstradiol affects the expression of CCNB1 mRNA21826169
D004958Estradiol[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA22534328
D004958Estradiol[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein22534328
D004958EstradiolEstradiol results in decreased expression of CCNB1 mRNA23094148
D004958EstradiolEstradiol results in increased expression of CCNB1 mRNA17445807|1916744
D004958EstradiolEstradiol results in increased expression of CCNB1 protein17445807
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]17445807
D004958EstradiolIGF1R mutant form inhibits the reaction [Estradiol results in decreased expression of CCNB1 mRNA]23094148
D004958EstradiolEstradiol results in increased expression of CCNB1 mRNA11861973|2557526
D004958EstradiolTetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]11861973
D004958EstradiolEstradiol results in increased expression of CCNB1 mRNA21980073|2637266
C095105bexarotenebexarotene results in decreased expression of CCNB1 protein19067706
D001629BezafibrateBezafibrate results in increased expression of CCNB1 mRNA15447978
C053541bicalutamidebicalutamide results in decreased expression of CCNB1 mRNA15887248
D001713Biphenyl CompoundsBiphenyl Compounds results in increased expression of CCNB1 mRNA21472861
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of CCNB1 mRNA27685785
D017438Bisphenol A-Glycidyl MethacrylateBisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA20673999
D017438Bisphenol A-Glycidyl MethacrylateBisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 protein20673999
D017438Bisphenol A-Glycidyl MethacrylateCAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in decreased expression of CCNB1 mRNA]20673999
C006780bisphenol Abisphenol A affects the expression of CCNB1 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of CCNB1 mRNA29027980
C006780bisphenol Abisphenol A affects the expression of CCNB1 mRNA21826169
C006780bisphenol Abisphenol A results in decreased expression of CCNB1 mRNA27979917|2927551
C006780bisphenol AAcetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]24909818
C006780bisphenol Abisphenol A results in increased expression of CCNB1 mRNA27623287
C006780bisphenol Abisphenol A results in increased expression of CCNB1 protein24909818
C006780bisphenol Aoligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]24909818
C006780bisphenol Abisphenol A results in decreased expression of CCNB1 mRNA25181051|2698221
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of CCNB1 mRNA17942131|1895870
D000069286BortezomibBortezomib results in increased expression of CCNB1 protein19074855
D000069286BortezomibBortezomib results in increased ubiquitination of and results in increased expression of CCNB1 protein20367638
D000069286Bortezomib[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of CCNB1 protein25522274
C023623brassinolidebrassinolide results in decreased expression of CCNB1 protein20833159
D001966BromineBromine results in increased expression of CCNB1 mRNA21391292
C073829Bupleuran 2IIcBupleuran 2IIc results in increased expression of CCNB1 protein14556967
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in decreased expression of CCNB1 mRNA25086368
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of CCNB1 mRNA19000923
D002084Butylated HydroxytolueneButylated Hydroxytoluene results in increased expression of CCNB1 mRNA12867420|1900092
D002084Butylated Hydroxytoluene[Butylated Hydroxytoluene results in increased expression of FOXM1 mRNA] which results in increased expression of CCNB1 mRNA12867420
D002087Butyrates[Butyrates co-treated with Camptothecin] results in decreased expression of CCNB1 protein16061681
D002087ButyratesButyrates results in decreased expression of CCNB1 protein16007142
D002087ButyratesButyrates results in decreased expression of CCNB1 mRNA14674679
D002104CadmiumCadmium results in decreased expression of CCNB1 mRNA21120746|2437683
D002104CadmiumCadmium results in increased expression of CCNB1 protein27071802
D002104CadmiumHMGA2 protein affects the reaction [Cadmium results in increased expression of CCNB1 protein]27071802
D002104CadmiumCadmium results in decreased expression of CCNB1 protein16730872
C028031cadmium acetatecadmium acetate affects the expression of CCNB1 mRNA16249259
D019256Cadmium Chloride"[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein]"26385184
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CCNB1 protein26385184
D019256Cadmium Chloridetyrphostin AG 1478 inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein]26385184
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CCNB1 mRNA23741332
D019256Cadmium ChlorideCadmium Chloride affects the expression of CCNB1 mRNA29287790
D019256Cadmium ChlorideCadmium Chloride affects the expression of CCNB1 protein29287790
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNB1 mRNA15501611|2006134
D019256Cadmium Chloride[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA12135628
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNB1 mRNA25993096
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CCNB1 protein16730872
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester results in decreased expression of CCNB1 protein16085347
D002110CaffeineCaffeine inhibits the reaction [Genistein results in increased expression of CCNB1 protein]19038232
D002110CaffeineCaffeine inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]9098629
D002110CaffeineCaffeine results in increased expression of CCNB1 protein20025956
D002110CaffeineCaffeine results in increased degradation of CCNB1 protein17182611
C553149camphorquinonecamphorquinone results in decreased expression of CCNB1 mRNA26658076
C553149camphorquinonecamphorquinone results in decreased expression of CCNB1 protein26658076
D002166Camptothecin[Butyrates co-treated with Camptothecin] results in decreased expression of CCNB1 protein16061681
D002211CapsaicinCapsaicin results in decreased expression of CCNB1 protein19939880
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CCNB1 mRNA17484886|2733941
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CCNB1 protein19887370
D002251Carbon TetrachloridePLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 mRNA]16006527
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CCNB1 mRNA24763279
C474928CB 403CB 403 results in increased expression of CCNB1 protein12694875
D000068579CelecoxibCelecoxib affects the expression of CCNB119846907
D002509CephaloridineCephaloridine results in decreased expression of CCNB1 mRNA18500788
D002701Chloramphenicol"[enterotoxin B, staphylococcal co-treated with Chloramphenicol] results in increased expression of CCNB1"18559535
D002706ChlordanChlordan results in increased expression of CCNB1 mRNA20403969
C035377chlorendic acidchlorendic acid results in increased expression of CCNB1 mRNA22584684
D002737ChloropreneChloroprene results in increased expression of CCNB1 mRNA23125180
D004390ChlorpyrifosChlorpyrifos results in decreased expression of CCNB1 mRNA21356183
D004390Chlorpyrifos[Copper co-treated with Chlorpyrifos] results in decreased expression of CCNB1 mRNA21356183
D004390ChlorpyrifosChlorpyrifos results in decreased expression of CCNB1 mRNA20691718
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNB1 mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of CCNB1 protein21670593
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of CCNB1 mRNA28472532
C074702chromium hexavalent ionAscorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein]21621607
C074702chromium hexavalent ionchromium hexavalent ion results in decreased expression of CCNB1 protein21621607
C043561chrysinchrysin results in decreased expression of CCNB1 mRNA18331776|1939799
C043561chrysinchrysin results in decreased expression of CCNB1 protein18331776|1939799
D002939CiprofloxacinCiprofloxacin results in decreased expression of CCNB1 protein10741713
D002939CiprofloxacinCiprofloxacin results in increased expression of CCNB1 mRNA18512786
D002939CiprofloxacinCiprofloxacin results in increased expression of CCNB1 protein18512786
D019343Citric Acid[Silver analog co-treated with Citric Acid] results in decreased expression of CCNB1 mRNA27021274
D002953CitrininCitrinin results in increased expression of CCNB1 mRNA23856526
D002994ClofibrateClofibrate results in decreased expression of CCNB1 mRNA22008536
C018021cobaltous chloridecobaltous chloride results in decreased expression of CCNB1 mRNA19320972|1937684
C018021cobaltous chloridecobaltous chloride results in decreased expression of CCNB1 mRNA24386269
D003078ColchicineColchicine results in increased expression of CCNB1 mRNA21472861
D003078ColchicineColchicine results in increased expression of CCNB1 protein27769712
D003300Copper[Copper co-treated with Chlorpyrifos] results in decreased expression of CCNB1 mRNA21356183
D003300CopperCopper results in decreased expression of CCNB1 mRNA21356183
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of CCNB1 mRNA20971185
D003300CopperCopper deficiency results in decreased expression of CCNB1 mRNA19497425
D003300CopperCopper results in increased expression of CCNB1 mRNA22465980
C464760copper-1,10-phenanthroline"copper-1,10-phenanthroline results in decreased expression of CCNB1 protein"24638265
D019327Copper SulfateCopper Sulfate results in decreased expression of CCNB1 mRNA19549813
D019327Copper SulfateCopper Sulfate results in increased secretion of CCNB1 protein24521407
D003345CorticosteroneCorticosterone results in decreased expression of CCNB1 mRNA15755911
D003345CorticosteroneCorticosterone results in decreased expression of CCNB1 protein15755911
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNB1 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of CCNB1 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of CCNB1 mRNA19167446
C024015cryptolepinecryptolepine results in decreased expression of CCNB1 mRNA16120219
C024015cryptolepinecryptolepine results in decreased expression of CCNB1 protein16120219
C038106cucurbitacin Icucurbitacin I results in decreased expression of CCNB1 protein24858077
C030973cupric oxidecupric oxide results in decreased expression of CCNB1 mRNA22077320
D003471CuprizoneCuprizone results in increased expression of CCNB1 mRNA26577399
D003474CurcuminCurcumin results in decreased expression of CCNB1 mRNA18719366
D003474CurcuminCurcumin results in decreased expression of CCNB1 protein17148446|1940170
D016572CyclosporineCyclosporine results in decreased expression of CCNB1 mRNA20106945|2163298
D016572CyclosporineCyclosporine results in decreased expression of CCNB1 mRNA17942131
D003571Cytochalasin BCytochalasin B results in decreased expression of CCNB1 protein27640744
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Progesterone results in increased metabolism of CCNB1 mRNA]"14694440
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of CCNB1 mRNA24317228
C014347decitabinedecitabine affects the methylation of CCNB1 gene17630775
C014347decitabinedecitabine results in increased expression of CCNB1 protein22534328
C014347decitabine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA22534328
C014347decitabinedecitabine results in decreased expression of CCNB1 mRNA27915011
D003676DeferoxamineDeferoxamine results in decreased expression of CCNB1 protein11468187
D003703DemecolcineDemecolcine results in increased expression of CCNB1 mRNA23649840
C576677demycarosyl-3D-digitoxosylmithramycin SKdemycarosyl-3D-digitoxosylmithramycin SK results in decreased expression of CCNB1 mRNA24907531
D003907DexamethasoneDexamethasone results in increased expression of CCNB1 mRNA23137833
D003907DexamethasoneDexamethasone results in decreased expression of CCNB1 mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of CCNB1 mRNA]20032058
C539263di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone"di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone affects the expression of CCNB1 protein"21750178
C028009diallyl disulfidediallyl disulfide results in decreased expression of CCNB1 protein16691315
C028009diallyl disulfidediallyl disulfide results in increased expression of CCNB1 protein19202565
C042577diallyl trisulfidediallyl trisulfide affects the localization of CCNB1 protein20143254
C042577diallyl trisulfidediallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]20143254
C042577diallyl trisulfidediallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]20143254
C042577diallyl trisulfidediallyl trisulfide results in increased expression of CCNB1 protein19823037|2441587
C023614dibenzofurandibenzofuran analog results in decreased expression of CCNB1 mRNA20566336
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CCNB1 mRNA28973377
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of CCNB1 mRNA17361019|2324252
D003994Bucladesine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA22534328
D003994Bucladesine[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein22534328
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of CCNB1 mRNA28962523
D002945Cisplatin"(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]"20195699
D002945Cisplatin[Cisplatin co-treated with fisetin] results in decreased expression of CCNB1 protein21216935
D002945Cisplatin[Cisplatin co-treated with Quercetin] results in increased expression of CCNB1 mRNA27514524
D002945CisplatinCisplatin results in decreased activity of CCNB1 protein21592546
D002945CisplatinCisplatin results in decreased activity of [CCNB1 protein binds to CDK1 protein]21592546
D002945CisplatinCisplatin results in decreased expression of CCNB1 mRNA27594783
D002945CisplatinCisplatin results in increased expression of CCNB1 protein19548002|2019569
D002945Cisplatin[Piroxicam co-treated with Cisplatin] results in decreased expression of CCNB1 mRNA21858171
D002945CisplatinTP53 protein inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]19548002
D002945CisplatinCaffeine inhibits the reaction [Cisplatin results in increased expression of CCNB1 protein]9098629
D002945CisplatinCisplatin results in decreased expression of CCNB1 mRNA25270620
D002945CisplatinCisplatin results in increased expression of CCNB1 mRNA21151649
D002945CisplatinCisplatin results in increased expression of CCNB1 protein9098629
D002945CisplatinCisplatin results in decreased expression of CCNB1 mRNA22023808
C000944dicrotophosdicrotophos results in decreased expression of CCNB1 mRNA28302478
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of CCNB1 mRNA26924002
C552234didymindidymin results in decreased expression of CCNB1 protein27899290
C552234didyminlocostatin inhibits the reaction [didymin results in decreased expression of CCNB1 protein]27899290
D004026DieldrinDieldrin results in increased expression of CCNB1 mRNA20438755
D004026DieldrinDieldrin affects the expression of CCNB1 mRNA22546817
D004026DieldrinDieldrin results in increased expression of CCNB1 mRNA23153324
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of CCNB1 mRNA19000923|2570120
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of CCNB1 mRNA22584684
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCNB1 mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CCNB1 mRNA17854601|1999628
D004052DiethylnitrosamineRB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB1 mRNA]17854601
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNA18164116
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 mRNA12616621
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 protein12616621
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA12616621
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein12616621
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CCNB1 mRNA25242409
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNB1 mRNA22129741
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CCNB1 protein14990787
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CCNB1 protein16336677
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CCNB1 mRNA15890375
C011612diethyl sulfatediethyl sulfate affects the expression of CCNB1 protein23887207
C035318diethylthioureadiethylthiourea results in increased expression of CCNB1 mRNA22584684
D004074DigitoxinDigitoxin analog results in decreased expression of CCNB1 protein22037315
D004074DigitoxinDigitoxin analog results in decreased expression of [CCNB1 protein binds to CDK1 protein]22037315
D004074DigitoxinDigitoxin results in decreased expression of CCNB1 protein22037315
D004074DigitoxinDigitoxin results in decreased expression of [CCNB1 protein binds to CDK1 protein]22037315
C539241dihydroptychantol Adihydroptychantol A results in decreased expression of CCNB1 protein21185854
D000875AnthralinAnthralin results in increased expression of CCNB1 protein20025956
D002117CalcitriolCalcitriol results in decreased expression of CCNB1 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in decreased expression of CCNB1 mRNA21592394
C541783dimethyl alpha-ketoglutaratedimethyl alpha-ketoglutarate inhibits the reaction [tributyltin results in decreased expression of CCNB1 protein]26961604
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CCNB1 protein"20025956
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CCNB1 mRNA15890375
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of CCNB1 mRNA22302311
D004147DioxinsDioxins affects the expression of CCNB1 mRNA20463971
C067311docetaxeldocetaxel results in increased expression of and results in increased activity of CCNB1 protein16731754
D004317Doxorubicin"[2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with Doxorubicin] results in decreased expression of CCNB1 protein"20826841
D004317DoxorubicinCCNB1 protein affects the susceptibility to Doxorubicin16928833
D004317DoxorubicinDoxorubicin affects the expression of CCNB1 protein17893511
D004317DoxorubicinDoxorubicin promotes the reaction [RBL2 protein binds to CCNB1 promoter]16537896
D004317DoxorubicinDoxorubicin results in decreased expression of CCNB120222868
D004317DoxorubicinDoxorubicin results in decreased expression of CCNB1 mRNA15205334
D004317DoxorubicinDoxorubicin results in decreased expression of CCNB1 protein15141020
D004317DoxorubicinDoxorubicin results in increased expression of CCNB1 protein17320279|2082684
D004317DoxorubicinGo 6976 inhibits the reaction [Doxorubicin results in increased expression of CCNB1 protein]17320279
D004317DoxorubicinDoxorubicin promotes the reaction [AZD 6244 results in decreased expression of CCNB1 protein]17876044
D004317Doxorubicin[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 protein19789217
D004391DustDust results in decreased expression of CCNB1 mRNA17805423
C034192ellipticineellipticine results in decreased expression of CCNB1 protein16027529
C034192ellipticineellipticine results in increased expression of CCNB1 protein21843585
C031818enterotoxin B, staphylococcal"[enterotoxin B, staphylococcal co-treated with Chloramphenicol] results in increased expression of CCNB1"18559535
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CCNB1 mRNA22079256
C007366erythritol anhydrideAcetylcysteine inhibits the reaction [erythritol anhydride results in increased expression of CCNB1 protein]25633853
C007366erythritol anhydrideerythritol anhydride results in increased expression of CCNB1 protein25633853
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of CCNB1 mRNA24412560
D004918Erythromycin EstolateErythromycin Estolate results in increased expression of CCNB1 mRNA24412560
C007633estragoleestragole results in increased expression of CCNB1 mRNA29054680
D004964EstriolEstriol results in increased expression of CCNB1 mRNA25575267
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CCNB1 mRNA17351261
D005047EtoposideEtoposide results in decreased expression of CCNB1 mRNA16120219
D005047EtoposideEtoposide results in decreased expression of CCNB1 protein16120219
D005054EugenolEugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA]19851710
D015025ZearalenoneZearalenone results in decreased expression of CCNB1 mRNA27862621
C024555ferric chlorideferric chloride results in increased expression of CCNB1 protein20025956
C029451ferrous chlorideferrous chloride results in increased expression of CCNB1 protein20025956
C082360fipronilfipronil results in increased expression of CCNB1 mRNA23962444
C017875fisetin[Cisplatin co-treated with fisetin] results in decreased expression of CCNB1 protein21216935
C017875fisetinfisetin results in decreased expression of CCNB1 protein21216935|2818138
D044950FlavanonesFlavanones results in decreased expression of CCNB1 protein21616090
C012976flumequine"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CCNB1 mRNA"23681119
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of CCNB1 protein15158336
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CCNB1 mRNA22584684
D005472FluorouracilFluorouracil results in decreased expression of CCNB1 mRNA15205334|1655759
D005472FluorouracilFluorouracil results in decreased expression of CCNB1 protein15546879
D005472Fluorouracil"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]"15546879
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]15016801
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]15546879
D005472Fluorouracil"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]"15546879
D005472FluorouracilFluorouracil results in decreased expression of CCNB120633010
D005473FluoxetineFluoxetine results in decreased expression of CCNB1 mRNA21497159
D005480FlurbiprofenFlurbiprofen results in decreased expression of CCNB1 protein11687965
D005492Folic Acid[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNB1 mRNA24657277
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNB1 mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of CCNB1 mRNA23649840
C007768formononetinformononetin results in increased expression of CCNB1 protein28414026
C007768formononetinXI-006 inhibits the reaction [formononetin results in increased expression of CCNB1 protein]28414026
C007768formononetinformononetin results in increased expression of CCNB1 protein28414026
C058728fosbretabulinfosbretabulin analog results in increased expression of CCNB1 protein25529822
D005620Freund's Adjuvant[Urethane co-treated with Freund's Adjuvant] results in increased expression of CCNB1 mRNA12400877
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]17445807
C070081fulvestrantfulvestrant results in increased expression of CCNB1 mRNA12154049
C070081fulvestrantfulvestrant results in decreased expression of CCNB1 mRNA21980073
C039281furanfuran results in increased expression of CCNB1 mRNA22079235|2553966
C056507gemcitabinegemcitabine results in decreased expression of CCNB1 mRNA20103597
C056507gemcitabinegemcitabine results in increased expression of CCNB1 protein11504793
D019833GenisteinGenistein affects the expression of CCNB1 mRNA18214933
D019833Genistein2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein]19038232
D019833GenisteinCaffeine inhibits the reaction [Genistein results in increased expression of CCNB1 protein]19038232
D019833GenisteinGenistein affects the expression of CCNB1 mRNA18847459
D019833GenisteinGenistein affects the expression of CCNB1 protein10601582
D019833GenisteinGenistein results in increased expression of CCNB1 protein19038232
D019833GenisteinU 0126 inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein]19038232
D019833GenisteinGenistein results in increased expression of CCNB1 mRNA26792615
D019833Genistein[Genistein co-treated with vinclozolin] results in decreased expression of CCNB1 mRNA23160963
C007845gingerolgingerol results in decreased expression of CCNB1 mRNA28249781
C007845gingerolgingerol results in decreased expression of CCNB1 protein28249781
D005944GlucosamineGlucosamine results in decreased expression of CCNB1 mRNA17109745
C004312glycidolglycidol results in decreased expression of CCNB1 mRNA24915197
C010974glyphosateglyphosate affects the expression of CCNB1 protein15375296
C081021Go 6976Go 6976 inhibits the reaction [Doxorubicin results in increased expression of CCNB1 protein]17320279
C103280goniothalamingoniothalamin results in decreased expression of CCNB1 mRNA26522230
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CCNB1 mRNA24763279
C568713GSK1210151AGSK1210151A results in decreased expression of CCNB1 mRNA26877780
C568713GSK1210151AGSK1210151A results in decreased expression of CCNB1 protein26877780
C479979GW0742[GW0742 binds to and results in increased activity of PPARD protein] which results in decreased expression of CCNB1 protein22473992
C401858GW 7604GW 7604 results in increased expression of CCNB1 mRNA12154049
C001330hellebrigeninhellebrigenin results in increased expression of CCNB1 protein24954031
D006533HeptachlorHeptachlor results in increased expression of CCNB1 mRNA23153324
D006540HerbicidesHerbicides results in decreased activity of CCNB1 protein11896679
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde affects the expression of CCNB1 mRNA22302311
C070164homocastasteronehomocastasterone results in decreased expression of CCNB1 protein20833159
D017313FenretinideFenretinide results in increased expression of CCNB1 mRNA28973697
C029424hydrazinehydrazine results in decreased expression of CCNB1 mRNA15282401
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CCNB1 mRNA20044591
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CCNB1 protein21179406
D006918HydroxyureaHydroxyurea results in increased expression of CCNB1 protein11468187
D006918HydroxyureaHydroxyurea results in decreased expression of CCNB1 protein16356682
C492448ICG 001ICG 001 results in decreased expression of CCNB1 mRNA26191083
C016517indole-3-carbinolindole-3-carbinol affects the expression of CCNB1 mRNA21396975
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNB1 mRNA22129741
D007213IndomethacinIndomethacin results in decreased expression of CCNB1 protein11504793
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of CCNB1 mRNA25613284
C051890irinotecanirinotecan results in decreased expression of CCNB1 mRNA20097248
C545474JAI-51JAI-51 results in increased expression of CCNB1 protein24134853
C544151jinfukangjinfukang results in increased expression of CCNB1 mRNA27392435
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of CCNB1 mRNA27169980
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CCNB1 mRNA24796395|2687778
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CCNB1 protein26877780
C410337K 7174K 7174 results in decreased expression of CCNB1 mRNA24086573
C006552kaempferolkaempferol results in decreased expression of CCNB1 mRNA18331776|1939799
C006552kaempferolkaempferol results in decreased expression of CCNB1 protein18331776|1939799
C524169kaempferol 7-O-glucosidekaempferol 7-O-glucoside results in decreased expression of CCNB1 mRNA18343026
C524169kaempferol 7-O-glucosidekaempferol 7-O-glucoside results in decreased expression of CCNB1 protein18343026
C011890kojic acidkojic acid results in increased expression of CCNB1 mRNA19000923
D007840LatexLatex analog results in increased expression of CCNB1 mRNA24768652
D007854LeadLead affects the expression of CCNB1 mRNA28903495
D007854LeadLead results in increased expression of CCNB120390873
C045463leflunomideleflunomide results in decreased expression of CCNB1 mRNA28988120
C045463leflunomideleflunomide results in decreased expression of CCNB1 mRNA24136188
C523615levistolide Alevistolide A inhibits the reaction [PDGFB protein results in increased expression of CCNB1 protein]17520522
C095104LG 100268LG 100268 results in decreased expression of CCNB1 protein15729575
D008012LidocaineLidocaine affects the expression of CCNB1 mRNA18931217
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CCNB1 mRNA10975854
D008095Lithocholic AcidLithocholic Acid results in increased expression of CCNB1 mRNA19000923
C000589248LL-202LL-202 results in decreased expression of CCNB1 protein24752227
C529490locostatinlocostatin inhibits the reaction [didymin results in decreased expression of CCNB1 protein]27899290
C581034longikaurin Alongikaurin A results in decreased expression of CCNB1 protein28801140
D008154LucanthoneLucanthone results in decreased expression of CCNB1 mRNA21148553
D047311LuteolinLuteolin results in decreased expression of CCNB1 mRNA18331776|1939799
D047311LuteolinLuteolin results in decreased expression of CCNB1 protein18331776|1939799
C005095malachite greenmalachite green results in decreased expression of CCNB1 protein16085357
C005095malachite green[Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 mRNA12616621
C005095malachite green[Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 protein12616621
C013592mangiferinmangiferin results in increased expression of CCNB1 mRNA20518311
C054474manumycinmanumycin inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA]25051199
D008466MechlorethamineMechlorethamine results in decreased activity of CCNB1 protein8463339
D008466MechlorethamineMechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]8463339
D008466MechlorethaminePentoxifylline inhibits the reaction [Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]]8463339
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA22534328
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein22534328
D008550MelatoninMelatonin results in decreased expression of CCNB1 mRNA21108658
D008550MelatoninMelatonin results in decreased expression of CCNB1 protein21108658
C005108metanil yellow[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA12616621
C005108metanil yellow[Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein12616621
D008694MethamphetamineMethamphetamine results in decreased expression of CCNB1 mRNA28341135
D008694MethamphetamineMethamphetamine results in decreased expression of CCNB1 protein28341135
D008701MethapyrileneMethapyrilene results in increased expression of CCNB1 mRNA15890375|2258468
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCNB1 mRNA20938992
D008727Methotrexate[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of CCNB1 mRNA24657277
D008727MethotrexateMethotrexate results in decreased expression of CCNB1 mRNA24657277
D008727MethotrexateMethotrexate results in increased expression of CCNB1 protein19548002
D008727MethotrexateTP53 protein inhibits the reaction [Methotrexate results in increased expression of CCNB1 protein]19548002
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CCNB1 mRNA20713471
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CCNB1 mRNA26372666
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of CCNB1 mRNA20061341
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of CCNB1 mRNA27544571
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of CCNB1 mRNA20039754
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CCNB1 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CCNB1 mRNA23649840
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA12135628
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in decreased expression of CCNB1 mRNA11516527
D008769MethylnitronitrosoguanidineEugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA]19851710
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of CCNB1 mRNA19851710
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of CCNB1 mRNA25270620
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of CCNB1 mRNA24810058
D0156551-Methyl-4-phenylpyridiniumU 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CCNB1 mRNA]12710931
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CCNB1 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of CCNB1 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CCNB1 mRNA]"20230807
C033069methyl salicylatemethyl salicylate affects the expression of CCNB1 mRNA22302311
C008493methylselenic acidmethylselenic acid results in decreased expression of CCNB1 mRNA11830524
C008493methylselenic acidmethylselenic acid results in decreased expression of CCNB1 protein11830524
C011309mezereinmezerein results in increased expression of CCNB1 mRNA19000923
D008917MirexMirex results in increased expression of CCNB1 mRNA23153324
D016685MitomycinMitomycin promotes the reaction [TP53 protein results in increased expression of CCNB1 mRNA]18647660
D016685MitomycinMitomycin results in increased expression of CCNB1 mRNA12760830|1864766
D016685MitomycinMitomycin results in decreased expression of CCNB1 mRNA25270620
C517284monomethyl phthalatemonomethyl phthalate affects the expression of CCNB1 mRNA26924002
C008548morinmorin results in decreased expression of CCNB1 mRNA28689916
D009151Mustard GasMustard Gas results in decreased expression of CCNB1 mRNA25102026
C040015myricetinmyricetin results in decreased expression of CCNB1 mRNA19397994
C040015myricetinmyricetin results in decreased expression of CCNB1 protein19397994
C059685N(1),N(11)-diethylnorspermine"N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]"15546879
C059685N(1),N(11)-diethylnorspermine"TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]"15546879
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CCNB1 protein11504793
C000594115N'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazide4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [N'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazide results in increased expression of CCNB1 protein]24748653
C000594115N'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazideN'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazide results in increased expression of CCNB1 protein24748653
C554954N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochlorideN-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride results in increased expression of CCNB1 mRNA28174063
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein]"20540935
D019810Sodium AzideSodium Azide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]12730239
D019810Sodium AzideSodium Azide results in decreased expression of CCNB1 mRNA12730239
D019810Sodium AzideSodium Azide results in decreased expression of CCNB1 protein12730239
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of CCNB1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CCNB1 mRNA"25554681
C576077N-benzoyl-12-nitrodehydroabietylamine-7-oneN-benzoyl-12-nitrodehydroabietylamine-7-one results in decreased expression of CCNB1 protein22743618
D009532NickelNickel results in increased expression of CCNB1 mRNA25583101
C022838nickel chloridenickel chloride affects the expression of CCNB1 mRNA22546817
C017557nickel subsulfidenickel subsulfide results in increased expression of CCNB1 mRNA24952340
D009538NicotineNicotine results in increased expression of CCNB1 protein20106947
D009538Nicotine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of CCNB1 mRNA"20230807
D009538Nicotine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CCNB1 mRNA]"20230807
D0151124-Nitroquinoline-1-oxide4-Nitroquinoline-1-oxide results in decreased expression of CCNB1 mRNA22561872
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of CCNB1 mRNA17616710
D015739NocodazoleNocodazole analog results in increased expression of CCNB1 protein28412508
D015739NocodazoleNocodazole results in increased expression of CCNB1 protein21670593
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of CCNB1 mRNA20971185
C025589ochratoxin A2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C025589ochratoxin A2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C025589ochratoxin AMAPK1 protein promotes the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C025589ochratoxin AMAPK1 protein promotes the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C025589ochratoxin Aochratoxin A inhibits the reaction [CCNB1 protein binds to CDK1 protein]20060447
C025589ochratoxin Aochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]22230261
C025589ochratoxin Aochratoxin A results in decreased expression of CCNB1 mRNA20060447
C025589ochratoxin Aochratoxin A results in decreased expression of CCNB1 protein20060447|2223026
C025589ochratoxin ASB 203580 inhibits the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C025589ochratoxin ASB 203580 inhibits the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C025589ochratoxin Aochratoxin A results in increased expression of CCNB1 mRNA19237604|1971763
C031004oligomycin Aoligomycin A inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]24909818
C507134ON 01910ON 01910 results in decreased expression of CCNB1 mRNA19029951
C507134ON 01910ON 01910 results in decreased expression of CCNB1 protein25316768
C507134ON 01910ON 01910 results in increased expression of CCNB1 mRNA19029951
C507134ON 01910ON 01910 results in increased expression of CCNB1 protein19029951|2547247
C016340o,p'-DDT"o,p'-DDT results in increased expression of CCNB1 mRNA"20686349
C016340o,p'-DDT"o,p'-DDT affects the expression of CCNB1 mRNA"17984292
D008939MitotaneMitotane results in increased expression of and results in increased localization of CCNB1 protein18509009
C030110oxaliplatinoxaliplatin results in decreased expression of CCNB1 protein19735649
C030110oxaliplatinoxaliplatin results in increased expression of CCNB1 protein15204521
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CCNB1 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of CCNB1 mRNA25729387
D010100Oxygen[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 mRNA19825857
D010100Oxygen[arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 protein19825857
D010100OxygenOxygen deficiency results in increased expression of CCNB1 protein26476374
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of CCNB1 protein]26476374
D010126Ozone[Ozone co-treated with NOTCH3 gene mutant form] affects the expression of CCNB1 mRNA25658374
D010126OzoneOzone results in decreased expression of CCNB1 mRNA16183385
D010126OzoneOzone results in decreased expression of CCNB1 protein16183385
D010126OzoneOzone results in increased expression of CCNB1 mRNA25658374
D010126OzoneTTPA protein affects the reaction [Ozone results in increased expression of CCNB1 mRNA]19555225
D017239Paclitaxel4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]24748653
D017239Paclitaxelalvocidib inhibits the reaction [Paclitaxel results in increased expression of CCNB1 protein]10430095
D017239PaclitaxelCCNB1 protein results in increased susceptibility to Paclitaxel16849574
D017239PaclitaxelCDK7 protein affects the reaction [Paclitaxel results in increased activity of [CDK2 protein binds to CCNB1 protein]]14646529
D017239PaclitaxelPaclitaxel affects the expression of CCNB1 protein27769712
D017239PaclitaxelPaclitaxel results in increased activity of [CDK2 protein binds to CCNB1 protein]14646529
D017239PaclitaxelPaclitaxel results in increased expression of and results in increased activity of CCNB1 protein16356831
D017239PaclitaxelPaclitaxel results in increased expression of CCNB1 protein10430095|2474865
D017239Paclitaxel[pifithrin co-treated with Paclitaxel] results in increased expression of CCNB1 protein18516295
C500026palbociclibpalbociclib results in decreased expression of CCNB1 mRNA22869556
C010272palytoxinpalytoxin results in increased expression of CCNB1 protein20025956
C482884panduratin Apanduratin A results in decreased expression of CCNB1 protein16497706
C418868PBOX-6[alvocidib co-treated with PBOX-6] results in decreased expression of CCNB1 protein20206141
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CCNB1 mRNA"25510870
C008776pelargonic acidpelargonic acid affects the expression of CCNB1 mRNA22302311
D010416PentachlorophenolPentachlorophenol results in increased expression of CCNB1 mRNA24642059
D010431PentoxifyllinePentoxifylline inhibits the reaction [Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]]8463339
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CCNB1 mRNA23427857
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CCNB1 mRNA25868421
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of CCNB1 mRNA26678675
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of CCNB1 protein26678675
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCNB1 mRNA24535843
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of CCNB1 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in increased expression of CCNB1 mRNA19482888|2309116
D010634PhenobarbitalPhenobarbital results in decreased expression of CCNB1 mRNA22008536
D010634PhenobarbitalPhenobarbital results in increased expression of CCNB1 mRNA19162173|2258468
D009764o-Phthalaldehydeo-Phthalaldehyde affects the expression of CCNB1 mRNA22302311
C121565pifithrin[pifithrin co-treated with Paclitaxel] results in increased expression of CCNB1 protein18516295
C121565pifithrinpifithrin inhibits the reaction [Azacitidine results in decreased expression of CCNB1 protein]15547111
C121565pifithrinpifithrin results in increased expression of CCNB1 mRNA16620711
C121565pifithrinpifithrin results in increased expression of CCNB1 protein16620711
C060836pioglitazonepioglitazone results in decreased expression of CCNB1 protein15729575
C008922piperinepiperine inhibits the reaction [IL2 protein results in increased expression of CCNB1 protein]25655587
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CCNB1 mRNA15890375|2248451
C027260pirarubicinpirarubicin results in decreased expression of CCNB1 protein22580740
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CCNB1 mRNA19710929
C006253pirinixic acidNCF1 protein affects the reaction [pirinixic acid results in increased expression of CCNB1 protein]17483499
C006253pirinixic acid[pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA23626729
C006253pirinixic acidpirinixic acid results in increased expression of CCNB1 mRNA18301758|1917653
C006253pirinixic acidpirinixic acid results in increased expression of CCNB1 protein17483499|1974812
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid results in increased expression of CCNB1 protein]17483499
C006253pirinixic acidRXRA protein promotes the reaction [pirinixic acid results in increased expression of CCNB1 mRNA]19176532
C006253pirinixic acidpirinixic acid results in increased expression of CCNB1 mRNA12832660|1589037
D010894Piroxicam[Piroxicam co-treated with Cisplatin] results in decreased expression of CCNB1 mRNA21858171
D010936Plant Extractsalpha-naphthoflavone inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA]25051199
D010936Plant Extractsmanumycin inhibits the reaction [Plant Extracts results in decreased expression of CCNB1 mRNA]25051199
D010936Plant ExtractsPlant Extracts results in decreased expression of CCNB1 mRNA25051199
D010936Plant ExtractsPlant Extracts results in increased expression of CCNB1 mRNA23557933
D011092Polyethylene Glycols[Silver analog co-treated with Polyethylene Glycols] results in decreased expression of CCNB1 mRNA27021274
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in decreased expression of CCNB1 mRNA24583197
D011134PolysaccharidesPolysaccharides affects the localization of CCNB1 protein20694826
C019536potassium bromate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CCNB1 protein]20067818
C019536potassium bromatepotassium bromate results in increased expression of CCNB1 protein20067818
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CCNB1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CCNB1 mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CCNB1 mRNA26348139
D011192Potassium DichromatePotassium Dichromate results in decreased expression of CCNB1 protein26348139
D011285Pregnenolone Carbonitrile"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA"23626729
D011285Pregnenolone Carbonitrile[pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA23626729
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of CCNB1 mRNA19162173
D011374ProgesteroneProgesterone results in decreased expression of CCNB1 mRNA18037150
D011374ProgesteroneProgesterone results in increased expression of CCNB1 mRNA18070364
D011374ProgesteroneProgesterone results in increased expression of CCNB1 mRNA19000923
D011374ProgesteroneProgesterone results in decreased expression of CCNB1 mRNA19690047
D011374ProgesteroneProgesterone results in decreased expression of CCNB1 mRNA20726854
D011374Progesterone"2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Progesterone results in increased metabolism of CCNB1 mRNA]"14694440
C005556propionaldehydepropionaldehyde results in decreased expression of CCNB1 mRNA26079696
D015742PropofolPropofol results in decreased expression of CCNB1 protein28804952
D011441PropylthiouracilPropylthiouracil results in increased expression of CCNB1 mRNA24780913
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [6-(N,N-dimethylamino)-2-(naphthalene-1-yl)-4-quinazolinone results in increased expression of CCNB1 protein]"23212307
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of CCNB1 mRNA"21152443
D011794Quercetin[Cisplatin co-treated with Quercetin] results in increased expression of CCNB1 mRNA27514524
D011794QuercetinQuercetin inhibits the reaction [NFYA protein binds to CCNB1 promoter]19009557
D011794QuercetinQuercetin results in decreased expression of CCNB1 mRNA18331776|1900955
D011794QuercetinQuercetin results in decreased expression of CCNB1 protein10601582|1604970
D011794QuercetinQuercetin affects the expression of CCNB115067354
D011794QuercetinQuercetin affects the phosphorylation of CCNB1 protein15067354
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of CCNB1 protein]26476374
C037219quinolinequinoline analog results in increased expression of CCNB1 protein18645022
D011804QuinolinesQuinolines analog results in increased expression of CCNB1 protein15826604
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of CCNB1 mRNA12154049|1744580
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of CCNB1 protein17445807
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of CCNB1 mRNA19167446
C059514resveratrolresveratrol affects the activity of [CCNB1 protein co-treated with CDK1 protein]12392819
C059514resveratrolresveratrol affects the expression of CCNB1 protein12392819|2352218
C059514resveratrol[resveratrol co-treated with temozolomide] results in increased expression of CCNB1 protein23522185
C059514resveratrolresveratrol results in decreased activity of [CCNB1 protein binds to CDK1 protein]17050787
C059514resveratrolresveratrol results in decreased expression of CCNB1 mRNA23137833
C059514resveratrolresveratrol results in decreased expression of CCNB1 protein11895924|1705078
C059514resveratrolresveratrol results in increased expression of CCNB1 protein11577002
C059514resveratrolresveratrol results in decreased expression of CCNB1 mRNA24330398
D012176RetinoidsRetinoids results in decreased expression of CCNB1 protein19067706
C547185riccardin Driccardin D results in decreased expression of CCNB1 mRNA24069304
C547185riccardin Driccardin D results in decreased expression of CCNB1 protein24069304
C089032rimonabantrimonabant results in increased expression of CCNB1 protein19479993
D019438RitonavirRitonavir results in decreased expression of CCNB1 mRNA19386116
C087123romidepsinromidepsin results in decreased expression of CCNB1 protein15014036
C089730rosiglitazonerosiglitazone results in decreased expression of CCNB1 protein15729575
C089730rosiglitazonerosiglitazone results in decreased expression of CCNB1 protein17077279
C093642SB 203580SB 203580 inhibits the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C093642SB 203580SB 203580 inhibits the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
D012643SeleniumSelenium deficiency results in decreased expression of CCNB1 mRNA11925459
C078903seocalcitolseocalcitol results in decreased expression of CCNB1 mRNA12040012
D017655Silicon CompoundsSilicon Compounds results in decreased expression of CCNB1 protein23620807
D012822Silicon DioxideSilicon Dioxide results in increased expression of CCNB1 mRNA25351596
D012834Silver[Silver analog co-treated with Citric Acid] results in decreased expression of CCNB1 mRNA27021274
D012834Silver[Silver analog co-treated with Polyethylene Glycols] results in decreased expression of CCNB1 mRNA27021274
D012834SilverSilver results in decreased expression of CCNB1 protein22546375
D012835Silver NitrateSilver Nitrate analog results in decreased expression of CCNB1 mRNA22831968
D012835Silver NitrateSilver Nitrate results in decreased expression of CCNB1 mRNA22831968
C440975silybinsilybin inhibits the reaction [Arsenic results in increased expression of CCNB1]25868784
D012839SimazineSimazine results in decreased expression of CCNB1 mRNA25461544
C574383sinularinAcetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CCNB1 protein]28548367
C574383sinularinsinularin results in decreased phosphorylation of CCNB1 protein28548367
C497103SK-7041SK-7041 results in decreased expression of CCNB1 protein16009488
C017947sodium arsenitesodium arsenite results in decreased expression of CCNB1 protein21642427
C017947sodium arsenitesodium arsenite results in increased expression of and results in decreased degradation of CCNB1 protein16614167
C017947sodium arsenitesodium arsenite results in increased expression of CCNB1 mRNA12016162
C017947sodium arsenitesodium arsenite results in increased stability of CCNB1 protein18501396
C017947sodium arseniteTP53 protein affects the reaction [sodium arsenite results in increased expression of and results in decreased degradation of CCNB1 protein]16614167
C017947sodium arsenitesodium arsenite results in decreased expression of CCNB1 mRNA16014739|1799827
C017947sodium arsenitesodium arsenite results in decreased expression of CCNB1 protein16338954
C016104sodium bichromatesodium bichromate results in increased expression of CCNB1 mRNA22561333
D012977Sodium NitriteSodium Nitrite results in increased expression of CCNB1 protein20025956
D018038Sodium Selenite"[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 mRNA"28757135
D018038Sodium Selenite"[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 protein"28757135
D018038Sodium SeleniteSodium Selenite results in decreased expression of CCNB1 mRNA24383545
D012999SomanSoman results in decreased expression of CCNB1 mRNA19281266
D012999SomanSoman results in increased expression of CCNB1 mRNA19281266
D053260SootSoot results in increased expression of CCNB1 mRNA22461453|2655175
C471405sorafenibsorafenib results in decreased expression of CCNB1 protein19139124
C561322sparstolonin Bsparstolonin B results in decreased expression of CCNB1 mRNA23940584
C075117squalestatin 1squalestatin 1 results in decreased expression of CCNB1 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of CCNB1 mRNA27225895
D013241SterigmatocystinMLH1 protein affects the reaction [Sterigmatocystin results in increased expression of CCNB1 protein]23296099
D013241SterigmatocystinSterigmatocystin results in decreased expression of [CCNB1 protein binds to CDK1 protein]23296099
D013241SterigmatocystinSterigmatocystin results in increased expression of CCNB1 mRNA23296099
D013241SterigmatocystinSterigmatocystin results in increased expression of CCNB1 protein23296099
D013412SulfadimethoxineSulfadimethoxine results in increased expression of CCNB1 mRNA19000923
D013449SulfonamidesSulfonamides analog results in increased expression of CCNB1 protein15826604
C016766sulforafansulforafan results in increased expression of CCNB1 protein15231455
D013467SulindacSulindac results in decreased expression of CCNB1 mRNA11906190
D014284TriiodothyronineTriiodothyronine affects the expression of CCNB1 mRNA17403546
D013629TamoxifenTamoxifen results in increased expression of CCNB1 protein16336677
D013629TamoxifenTamoxifen results in increased expression of CCNB1 mRNA12841865
C047246temozolomide[resveratrol co-treated with temozolomide] results in increased expression of CCNB1 protein23522185
D013739Testosterone[Testosterone co-treated with Calcitriol] results in decreased expression of CCNB1 mRNA21592394
D013739TestosteroneTestosterone results in decreased expression of CCNB1 mRNA21592394
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of CCNB1 mRNA]20032058
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of CCNB1 mRNA26988606
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNB1 mRNA16714409
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CCNB1 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]11861973
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCNB1 gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CCNB1 mRNA16102516
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CCNB1 mRNA19465110|2821309
D013755Tetradecanoylphorbol AcetatePPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]10866668
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA10866668|1900092
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of CCNB1 mRNA25613284
D013792Thalidomide[Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA18720364
D019284ThapsigarginThapsigargin results in decreased expression of CCNB1 mRNA22378314
D013849ThimerosalThimerosal results in increased expression of and results in increased activity of CCNB1 protein16649253
D013853ThioacetamideThioacetamide results in increased expression of CCNB1 mRNA22659510|2341159
D013974ThyroxineThyroxine results in increased expression of CCNB1 mRNA17403546
C009495titanium dioxidetitanium dioxide results in increased expression of CCNB1 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CCNB1 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CCNB1 mRNA20133372
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CCNB1 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of CCNB1 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of CCNB1 mRNA"19682533
C099150trabectedintrabectedin results in decreased expression of CCNB1 mRNA15961672
D014212TretinoinTretinoin results in decreased expression of CCNB1 protein16517207
D014212TretinoinTretinoin results in decreased expression of CCNB1 mRNA22498432
D014212TretinoinTretinoin results in decreased expression of CCNB1 protein22498432
D014212TretinoinTretinoin results in increased expression of CCNB1 protein20025956
C011559tributyltindimethyl alpha-ketoglutarate inhibits the reaction [tributyltin results in decreased expression of CCNB1 protein]26961604
C011559tributyltinIDH3A protein affects the reaction [tributyltin results in decreased expression of CCNB1 protein]26961604
C011559tributyltintributyltin results in decreased expression of CCNB1 protein26961604
D014241TrichloroethyleneTrichloroethylene results in increased expression of CCNB1 mRNA25549359
C012589trichostatin Atrichostatin A results in decreased expression of CCNB1 mRNA15901671
C012589trichostatin Atrichostatin A results in decreased expression of CCNB1 mRNA19606018|2377000
C012589trichostatin Atrichostatin A results in decreased expression of CCNB1 protein16009488|2377000
C020946triethylene glycol dimethacrylatetriethylene glycol dimethacrylate results in decreased expression of CCNB1 mRNA22486746
C020946triethylene glycol dimethacrylatetriethylene glycol dimethacrylate results in decreased expression of CCNB1 protein22486746
C015559trimellitic anhydridetrimellitic anhydride affects the expression of CCNB1 mRNA22302311
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of CCNB1 mRNA19042947
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNA17982090
C005445triphenyl phosphatetriphenyl phosphate results in decreased expression of CCNB1 mRNA26898711
C001899triptolidetriptolide results in increased expression of CCNB1 mRNA23639586
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of CCNB1 mRNA"26179874
C057693troglitazoneAspirin inhibits the reaction [troglitazone results in decreased expression of CCNB1 protein]19908241
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CCNB1 protein]20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein]"20540935
C057693troglitazonetroglitazone results in decreased expression of CCNB1 mRNA19140230
C057693troglitazonetroglitazone results in decreased expression of CCNB1 protein15729575|1990824
C004218tylophorinetylophorine analog results in increased expression of CCNB1 protein19284764
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein]26385184
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [EGF protein results in increased expression of CCNB1 protein]26385184
C113580U 0126U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of CCNB1 mRNA]12710931
C113580U 0126U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CCNB1 protein]19038232
D014520UrethaneHRAS protein promotes the reaction [Urethane results in increased expression of CCNB1 mRNA]26558449
D014520Urethane[Urethane co-treated with Freund's Adjuvant] results in increased expression of CCNB1 mRNA12400877
D014520UrethaneUrethane results in increased expression of CCNB1 mRNA26558449
D014527Uric AcidNLRP3 gene mutant form inhibits the reaction [Uric Acid results in decreased expression of CCNB1 mRNA]23619996
D014527Uric AcidUric Acid results in decreased expression of CCNB1 mRNA23619996
D014635Valproic AcidValproic Acid results in decreased expression of CCNB1 mRNA15901671
D014635Valproic AcidValproic Acid affects the expression of CCNB1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CCNB1 mRNA29154799
D014635Valproic AcidValproic Acid results in decreased expression of CCNB1 mRNA21427059
D014638VanadatesVanadates results in increased expression of CCNB1 mRNA19000923
C551177vemurafenib[(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of CCNB1 mRNA27169980
D014747VinblastineCCNB1 protein affects the susceptibility to Vinblastine16217747
D014747VinblastineCCNB1 protein results in increased susceptibility to Vinblastine16849574
C025643vinclozolin[Genistein co-treated with vinclozolin] results in decreased expression of CCNB1 mRNA23160963
D014750VincristineCCNB1 protein affects the susceptibility to Vincristine22178383
D014750VincristineVincristine results in increased expression of CCNB1 mRNA23649840
D014752Vinyl ChlorideVinyl Chloride results in increased expression of CCNB1 mRNA18579281
D012256RiboflavinRiboflavin affects the expression of CCNB120848206
C111237vorinostatvorinostat results in decreased expression of CCNB1 protein17417771
C009687wortmannin"[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein]"26385184
C009687wortmannin"[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CCNB1 protein]"26385184
C022186xanthatinxanthatin results in decreased expression of CCNB1 mRNA21568272
C000607970XI-006XI-006 inhibits the reaction [formononetin results in increased expression of CCNB1 protein]28414026
C118180XK 469XK 469 results in decreased ubiquitination of and results in increased expression of CCNB1 protein11774253
D015215Zidovudine[Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNB1 mRNA20370541
D015032ZincZinc deficiency results in increased expression of CCNB1 mRNA16140947
D015032ZincZinc deficiency results in increased expression of CCNB1 protein16140947
D015032ZincZinc inhibits the reaction [Zinc deficiency results in increased expression of CCNB1 mRNA]16140947
D015032ZincZinc inhibits the reaction [Zinc deficiency results in increased expression of CCNB1 protein]16140947
C016837zinc chloridezinc chloride results in increased expression of CCNB1 mRNA19000923
C000588918ziyuglycoside IIziyuglycoside II results in decreased expression of CCNB1 protein24680927
C088658zoledronic acidzoledronic acid results in decreased expression of CCNB1 mRNA20977926
C088658zoledronic acid[zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 protein19789217

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004672protein kinase activityCONTRIBUTES_TOIBA21873635  
GO:0004693cyclin-dependent protein serine/threonine kinase activity-TAS-  
GO:0005113patched binding-IPI11331587  
GO:0005515protein binding-IPI8756624  9001210  10373560  12612082  15251430  15790566  
17283331  18337751  18408765  19502428  19879842  20965177  
21952639  23397142  23602568  23799914  24358021  25241761  
25852190  26496610  
GO:0016538cyclin-dependent protein serine/threonine kinase regulator activity-IBA21873635  
GO:0019901protein kinase binding-IBA21873635  
GO:0019901protein kinase binding-IPI12524548  24746669  
GO:0035173histone kinase activityCONTRIBUTES_TOIBA21873635  
GO:0035173histone kinase activity-IEA-  
GO:0044389ubiquitin-like protein ligase binding-IPI15749827  
GO:0061575cyclin-dependent protein serine/threonine kinase activator activity-IDA24746669  
GO ID GO Term Qualifier Evidence PubMed
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity-IBA21873635  
GO:0000086G2/M transition of mitotic cell cycle-TAS-  
GO:0000278mitotic cell cycle-IBA21873635  
GO:0001556oocyte maturation-IEA-  
GO:0001701in utero embryonic development-IEA-  
GO:0001933negative regulation of protein phosphorylation-IEA-  
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-TAS-  
GO:0007052mitotic spindle organization-IMP18195732  
GO:0007077mitotic nuclear envelope disassembly-TAS-  
GO:0007080mitotic metaphase plate congression-IBA21873635  
GO:0007080mitotic metaphase plate congression-IMP18195732  
GO:0007088regulation of mitotic nuclear division-IBA21873635  
GO:0007283spermatogenesis-IEA-  
GO:0008284positive regulation of cell proliferation-IBA21873635  
GO:0009612response to mechanical stimulus-IEA-  
GO:0010629negative regulation of gene expression-IEA-  
GO:0010971positive regulation of G2/M transition of mitotic cell cycle-IDA24746669  
GO:0031145anaphase-promoting complex-dependent catabolic process-TAS-  
GO:0031442positive regulation of mRNA 3'-end processing-IEA-  
GO:0033129positive regulation of histone phosphorylation-IEA-  
GO:0042246tissue regeneration-IEA-  
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity-IEA-  
GO:0045787positive regulation of cell cycle-IBA21873635  
GO:0045931positive regulation of mitotic cell cycle-IMP18195732  
GO:0046680response to DDT-IEA-  
GO:0048146positive regulation of fibroblast proliferation-IEA-  
GO:0048565digestive tract development-IEA-  
GO:0051301cell division-IEA-  
GO:0051726regulation of cell cycle-TAS-  
GO:0051987positive regulation of attachment of spindle microtubules to kinetochore-IMP18195732  
GO:0055015ventricular cardiac muscle cell development-IEA-  
GO:0060045positive regulation of cardiac muscle cell proliferation-IEA-  
GO:0060623regulation of chromosome condensation-IEA-  
GO:0065003protein-containing complex assembly-IEA-  
GO:0071283cellular response to iron(III) ion-IEA-  
GO:0071398cellular response to fatty acid-IEA-  
GO:0071407cellular response to organic cyclic compound-IEA-  
GO:0071456cellular response to hypoxia-IEA-  
GO:0090266regulation of mitotic cell cycle spindle assembly checkpoint-IMP18195732  
GO:1905448positive regulation of mitochondrial ATP synthesis coupled electron transport-IDA24746669  
GO:2000775histone H3-S10 phosphorylation involved in chromosome condensation-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000307cyclin-dependent protein kinase holoenzyme complex-IBA21873635  
GO:0000922spindle pole-IDA18195732  
GO:0000942condensed nuclear chromosome outer kinetochore-IDA18195732  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA11331587  16109376  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA11331587  17850284  
GO:0005759mitochondrial matrixCOLOCALIZES_WITHIBA21873635  
GO:0005759mitochondrial matrixcolocalizes_withIDA24746669  
GO:0005813centrosome-IBA21873635  
GO:0005813centrosome-IDA12524548  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0016020membrane-IEA-  
GO:0097125cyclin B1-CDK1 complex-IBA21873635  
GO:0097125cyclin B1-CDK1 complex-IDA24746669  
KEGG ID KEGG Term
hsa04110Cell cycle
hsa04114Oocyte meiosis
hsa04115p53 signaling pathway
hsa04914Progesterone-mediated oocyte maturation
Reactome ID Reactome Term Evidence
R-HSA-113507E2F-enabled inhibition of pre-replication complex formationIEA
R-HSA-113510E2F mediated regulation of DNA replicationIEA
R-HSA-156711Polo-like kinase mediated eventsTAS
R-HSA-162658Golgi Cisternae Pericentriolar Stack ReorganizationIEA
R-HSA-1640170Cell CycleTAS
R-HSA-1640170Cell CycleIEA
R-HSA-174048APC/C:Cdc20 mediated degradation of Cyclin BTAS
R-HSA-174143APC/C-mediated degradation of cell cycle proteinsTAS
R-HSA-176408Regulation of APC/C activators between G1/S and early anaphaseTAS
R-HSA-176409APC/C:Cdc20 mediated degradation of mitotic proteinsTAS
R-HSA-176412Phosphorylation of the APC/CTAS
R-HSA-176417Phosphorylation of Emi1TAS
R-HSA-176814Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2299718Condensation of Prophase ChromosomesTAS
R-HSA-2465910MASTL Facilitates Mitotic ProgressionIEA
R-HSA-2500257Resolution of Sister Chromatid CohesionTAS
R-HSA-2514853Condensation of Prometaphase ChromosomesIEA
R-HSA-2565942Regulation of PLK1 Activity at G2/M TransitionTAS
R-HSA-2980766Nuclear Envelope BreakdownTAS
R-HSA-2980767Activation of NIMA Kinases NEK9, NEK6, NEK7TAS
R-HSA-3301854Nuclear Pore Complex (NPC) DisassemblyTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-4419969Depolymerisation of the Nuclear LaminaTAS
R-HSA-453274Mitotic G2-G2/M phasesTAS
R-HSA-453276Regulation of mitotic cell cycleTAS
R-HSA-453279Mitotic G1-G1/S phasesIEA
R-HSA-6791312TP53 Regulates Transcription of Cell Cycle GenesTAS
R-HSA-6804114TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle ArrestTAS
R-HSA-68875Mitotic ProphaseTAS
R-HSA-68875Mitotic ProphaseIEA
R-HSA-68877Mitotic PrometaphaseTAS
R-HSA-68877Mitotic PrometaphaseIEA
R-HSA-68886M PhaseTAS
R-HSA-68886M PhaseIEA
R-HSA-69206G1/S TransitionIEA
R-HSA-69273Cyclin A/B1/B2 associated events during G2/M transitionTAS
R-HSA-69275G2/M TransitionTAS
R-HSA-69278Cell Cycle, MitoticTAS
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-69473G2/M DNA damage checkpointTAS
R-HSA-69478G2/M DNA replication checkpointTAS
R-HSA-69481G2/M CheckpointsTAS
R-HSA-69620Cell Cycle CheckpointsTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-75035Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complexTAS
R-HSA-8852276The role of GTSE1 in G2/M progression after G2 checkpointTAS
R-HSA-8878166Transcriptional regulation by RUNX2TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26622675Pathogenic mechanisms of lung adenocarcinoma in smokers and non-smokers determined by gene expression interrogation. (2015 Sep)Hu YOncol Lett
14501029Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. (2003)Nordskog BKCardiovasc Toxicol