Gene: CD7

924
GP40|LEU-9|TP41|Tp40
CD7 molecule
protein-coding
17q25.3
Ensembl:ENSG00000173762 MIM:186820 Vega:OTTHUMG00000178662 UniprotKB:P09564
NC_000017.11
PubMed
0   ANCO-SNPs
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.538e-1 (AD)  3.376e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GNLY0.749
ELF40.727
NOD20.72
IL2RG0.714
PLEKHA40.712
FCGR2C0.702
RHOH0.702
CMTM30.701
NKG70.693
LILRB20.692

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MYADML2-0.511
HRH3-0.501
NDST3-0.489
ST6GALNAC5-0.484
SLC1A6-0.483
ENTPD3-0.477
CHRNB2-0.474
NEUROD6-0.474
VSTM2A-0.471
SLITRK5-0.471

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of CD7 mRNA26690555
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of CD7 gene28458013
D001554BenzeneBenzene results in increased expression of CD7 mRNA19162166
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CD7 mRNA22316170
C006780bisphenol Abisphenol A results in decreased expression of CD7 mRNA25181051
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of CD7 mRNA28472532
D003907DexamethasoneDexamethasone results in increased expression of CD7 mRNA21041162
D002117CalcitriolCalcitriol results in increased expression of CD7 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of CD7 mRNA21592394
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD7 mRNA17942748
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of CD7 mRNA20846436
C069837fullerene C60fullerene C60 results in decreased expression of CD7 mRNA19167457
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CD7 mRNA23086925
D009151Mustard GasMustard Gas results in increased expression of CD7 mRNA15674843
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of CD7 mRNA25380136
C028007nickel monoxidenickel monoxide results in decreased expression of CD7 mRNA19167457
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of CD7 mRNA25729387
D010615PhenacetinPhenacetin results in decreased expression of CD7 mRNA17698508
C030299phenylhydrazinephenylhydrazine results in decreased expression of CD7 mRNA17698508
C006253pirinixic acidpirinixic acid results in decreased expression of CD7 mRNA17426115
D010936Plant ExtractsPlant Extracts results in decreased expression of CD7 mRNA23557933
D017035PravastatinPravastatin results in decreased expression of CD7 mRNA27225895
D017035PravastatinPravastatin results in decreased expression of CD7 mRNA27225895
D011374ProgesteroneProgesterone affects the expression of CD7 mRNA17251523
D011794QuercetinQuercetin results in increased expression of CD7 mRNA21632981
C075117squalestatin 1squalestatin 1 results in decreased expression of CD7 mRNA27225895
C075117squalestatin 1squalestatin 1 results in decreased expression of CD7 mRNA27225895
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of CD7 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of CD7 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD7 mRNA20106945|2163298
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD7 mRNA17942748
C009495titanium dioxidetitanium dioxide results in increased expression of CD7 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of CD7 mRNA25729387
D019772TopotecanTopotecan results in increased expression of CD7 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of CD7 mRNA"19682533
D014635Valproic AcidValproic Acid results in increased methylation of CD7 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0038023signaling receptor activity-TAS11485208  
GO ID GO Term Qualifier Evidence PubMed
GO:0002250adaptive immune response-IEA-  
GO:0006955immune response-TAS11485208  
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway-NAS11485208  
GO:0042110T cell activation-TAS11485208  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS1695199  3258561  
GO:0016020membrane-TAS3501369  
GO:0016021integral component of membrane-TAS11485208  
KEGG ID KEGG Term
hsa04640Hematopoietic cell lineage
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
10865416The effects of cigarette smoking on peripheral blood leukocytes and lymphocyte subpopulations: an urban population-based study in Thailand. (2000 Mar)Apibal SJ Med Assoc Thai
8158547The distribution of T-cell subsets among HTLV-I carriers in Japan. (1994 May)Welles SLJ Acquir Immune Defic Syndr