Gene info: ID 929

Gene: CD14

GENE ID: 929

Synonyms: -

Description: CD14 molecule

Gene type: protein-coding

Location: 5q31.3

dbXrefs: Ensembl:ENSG00000170458 MIM:158120 Vega:OTTHUMG00000129507 UniprotKB:P08571

RefSeq: NG_023178.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: OD|ND|AD

# Publications: 95

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 2.769e-1 (AD) 3.202e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
FCGR1A	0.936
ABI3	0.934
HCK	0.932
SPI1	0.93
LAIR1	0.922
CCR1	0.918
FCER1G	0.915
SASH3	0.914
CD300A	0.914
PTPN6	0.909

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ATP2C2	-0.438
ST6GAL2	-0.429
KCNIP3	-0.404
NEUROD6	-0.393
HES5	-0.379
MARCH4	-0.379
WNT7A	-0.378
CPLX3	-0.378
TMEM179	-0.367
SLC7A4	-0.365

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C003564	1,25-dihydroxyergocalciferol	"1,25-dihydroxyergocalciferol results in increased expression of CD14 protein"	22751936
C477819	15-deoxyprostaglandin J2	15-deoxyprostaglandin J2 results in increased expression of CD14 protein	12649303
C032668	1-nitropyrene	1-nitropyrene results in decreased expression of CD14 mRNA	19041380
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CD14 mRNA"	19114083
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C009828	2,4,5,2',5'-pentachlorobiphenyl	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C009828	2,4,5,2',5'-pentachlorobiphenyl	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C009828	2,4,5,2',5'-pentachlorobiphenyl	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C009828	2,4,5,2',5'-pentachlorobiphenyl	"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C533599	24a-homo-1,15-dihydroxyergocalciferol	"24a-homo-1,15-dihydroxyergocalciferol results in increased expression of CD14 protein"	22751936
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD14 mRNA"	23196670
C026137	3-hydroxyacetanilide	3-hydroxyacetanilide results in decreased expression of CD14 mRNA	18544908
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in increased expression of CD14 mRNA"	18648102
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased expression of CD14 mRNA	19191707
C025566	4-methylhistamine	[4-methylhistamine binds to and results in increased activity of HRH2 protein] which affects the expression of CD14 protein	14499251
D000082	Acetaminophen	[Dietary Carbohydrates co-treated with Acetaminophen] results in increased expression of CD14 mRNA	17093179
D000082	Acetaminophen	Acetaminophen affects the expression of CD14 mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in increased expression of CD14 mRNA	18544908
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D000171	Acrolein	Acrolein results in increased expression of CD14 mRNA	18515264
D000241	Adenosine	Adenosine results in increased expression of CD14 mRNA	21538184
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of CD14 mRNA	27153756
D016604	Aflatoxin B1	[Aflatoxin B1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	22445859
D016604	Aflatoxin B1	[Aflatoxin B1 co-treated with aflatoxin B2] results in decreased expression of CD14 protein	22445859
C029753	aflatoxin B2	[Aflatoxin B1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	22445859
C029753	aflatoxin B2	[Aflatoxin B1 co-treated with aflatoxin B2] results in decreased expression of CD14 protein	22445859
D000393	Air Pollutants	Air Pollutants results in increased expression of CD14 mRNA	21030725
D000393	Air Pollutants	Plant Preparations inhibits the reaction [Air Pollutants results in increased expression of CD14 mRNA]	21030725
D000395	Air Pollutants, Occupational	"Air Pollutants, Occupational results in decreased expression of CD14 mRNA"	23195993
C008088	alfacalcidol	[alfacalcidol co-treated with Lipopolysaccharides] results in increased expression of CD14 protein	15946915
C008088	alfacalcidol	alfacalcidol results in increased expression of CD14 protein	15946915
D000534	Alum Compounds	Alum Compounds results in decreased expression of CD14 protein	18390722
D000536	Aluminum Hydroxide	Aluminum Hydroxide results in decreased expression of CD14 protein	18390722
D000537	Aluminum Oxide	"[Nanotubes, Carbon co-treated with Aluminum Oxide] results in increased secretion of CD14 protein"	25598225
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of CD14 mRNA	16483693
C059765	amphotericin B, deoxycholate drug combination	"amphotericin B, deoxycholate drug combination results in increased expression of CD14 mRNA"	22863853
D000968	Antimycin A	Antimycin A results in increased expression of CD14 mRNA	10491287
D018501	Antirheumatic Agents	Antirheumatic Agents results in decreased expression of CD14 mRNA	24449571
D001151	Arsenic	Arsenic results in increased expression of CD14 mRNA	12928151
C006632	arsenic trioxide	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of CD14 mRNA	22521957
C006632	arsenic trioxide	arsenic trioxide results in increased expression of CD14 mRNA	23911876
C006632	arsenic trioxide	arsenic trioxide results in increased expression of CD14 protein	20226526
C006632	arsenic trioxide	gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]	20226526
C006632	arsenic trioxide	[gefitinib promotes the reaction arsenic trioxide] which results in increased expression of CD14 mRNA	20226526
C006632	arsenic trioxide	SB 203580 inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C006632	arsenic trioxide	arsenic trioxide results in increased expression of CD14 mRNA	15073043
C015001	arsenite	arsenite results in increased methylation of CD14 promoter	23974009
C015001	arsenite	arsenite results in decreased expression of CD14 mRNA	18191166
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of CD14 mRNA"	25757056
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of CD14 mRNA]	24239723
D000069059	Atorvastatin Calcium	Atorvastatin Calcium results in decreased expression of CD14 protein	18333374
D001379	Azathioprine	Azathioprine results in increased expression of CD14 mRNA	22623647
C416282	BAY 11-7085	BAY 11-7085 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
C416282	BAY 11-7085	BAY 11-7085 results in increased expression of CD14 protein	18180316
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CD14 mRNA]	19244278
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CD14 mRNA]	19244278
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CD14 mRNA	20064835
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CD14 mRNA	20106945
D001564	Benzo(a)pyrene	AHR protein affects the reaction [Benzo(a)pyrene affects the expression of CD14 mRNA]	22228805
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CD14 mRNA	19770486
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA	25566086
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]	25566086
D004958	Estradiol	Estradiol affects the expression of CD14 mRNA	15598610
D004958	Estradiol	Estradiol results in increased expression of CD14 mRNA	15289156\|1948475
C095105	bexarotene	bexarotene results in increased expression of CD14 mRNA	16648578
C006780	bisphenol A	bisphenol A results in decreased expression of CD14 mRNA	25594700
C006780	bisphenol A	bisphenol A affects the expression of CD14 mRNA	25181051
D002104	Cadmium	[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CD14 mRNA	21481475
D002104	Cadmium	[Cadmium co-treated with Calcitriol] results in increased expression of CD14 protein	20868229
D002104	Cadmium	U 0126 inhibits the reaction [[Cadmium co-treated with Calcitriol] results in increased expression of CD14 protein]	20868229
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of CD14 mRNA	26352046
D019256	Cadmium Chloride	Cadmium Chloride affects the expression of CD14 mRNA	22110744
C055494	caffeic acid phenethyl ester	caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of CD14 protein]	16766008
C055494	caffeic acid phenethyl ester	caffeic acid phenethyl ester results in increased expression of CD14 protein	16766008
C055494	caffeic acid phenethyl ester	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA	20360939
D002235	Carbofuran	Carbofuran results in increased expression of CD14 mRNA	20211217
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CD14 mRNA	18038451\|2733941
D002251	Carbon Tetrachloride	PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CD14 mRNA]	18038451
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of CD14 mRNA	14572767
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CD14 mRNA	16045604
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD14 mRNA	20938992
C418118	CI 1044	CI 1044 results in increased expression of CD14 mRNA	17569694
D002922	Ciguatoxins	Ciguatoxins affects the expression of CD14 mRNA	18353800
D002927	Cimetidine	Cimetidine results in decreased expression of CD14 protein	11556524
C019304	ciprofibrate	ciprofibrate results in increased expression of CD14 protein	12649303
D002994	Clofibrate	Clofibrate results in increased expression of CD14 protein	12649303
D002994	Clofibrate	Clofibrate affects the expression of CD14 mRNA	16081524
D002995	Clofibric Acid	Clofibric Acid affects the expression of CD14 mRNA	17602206
D002995	Clofibric Acid	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CD14 mRNA	17602206
D003078	Colchicine	Colchicine results in increased expression of CD14 mRNA	20624997
D003300	Copper	Copper results in increased expression of CD14 mRNA	22465980
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of CD14 mRNA	19549813
D003471	Cuprizone	Cuprizone results in increased expression of CD14 mRNA	27523638
D003474	Curcumin	Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]	18180316
D003474	Curcumin	Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D003520	Cyclophosphamide	Cyclophosphamide results in increased expression of CD14 mRNA	15331540\|2104116
D016572	Cyclosporine	Cyclosporine results in decreased expression of CD14 mRNA	20106945
D016572	Cyclosporine	Cyclosporine results in increased expression of CD14 mRNA	25562108
D016572	Cyclosporine	Cyclosporine results in increased expression of CD14 mRNA	25224403
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in decreased expression of CD14 mRNA	23640034
C014347	decitabine	[decitabine co-treated with TNF protein] results in increased expression of CD14 protein	19117987
C014347	decitabine	decitabine promotes the reaction [trichostatin A results in increased expression of CD14 mRNA]	18718068
C014347	decitabine	decitabine results in increased expression of CD14 mRNA	19151715
C107676	deguelin	[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein	25242579
C007262	deoxynivalenol	deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]	19549553
D003907	Dexamethasone	Dexamethasone results in increased expression of CD14 protein	10614771
D016264	Dextran Sulfate	CD14 protein inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]	28411859
D016264	Dextran Sulfate	Dextran Sulfate affects the susceptibility to CD14 protein	28411859
D016264	Dextran Sulfate	[Dextran Sulfate affects the susceptibility to CD14 protein] which affects the expression of IFNG mRNA	28411859
D004008	Diclofenac	Diclofenac results in increased expression of CD14 mRNA	26934552
D004040	Dietary Carbohydrates	[Dietary Carbohydrates co-treated with Acetaminophen] results in increased expression of CD14 mRNA	17093179
D004041	Dietary Fats	Dietary Fats results in decreased expression of CD14 mRNA	18042831
D004041	Dietary Fats	Dietary Fats results in increased expression of CD14 mRNA	22609946
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of CD14 mRNA	24535843
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA	20360939
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CD14 mRNA	17602206
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of CD14 mRNA	15171707
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CD14 mRNA	15289156\|2104116
D002117	Calcitriol	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
D002117	Calcitriol	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole promotes the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
D002117	Calcitriol	Benzo(a)pyrene promotes the reaction [Calcitriol results in increased expression of CD14 mRNA]	19244278
D002117	Calcitriol	[Cadmium co-treated with Calcitriol] results in increased expression of CD14 protein	20868229
D002117	Calcitriol	Calcitriol analog results in increased expression of CD14 protein	10799658
D002117	Calcitriol	Calcitriol promotes the reaction [MZF1 protein binds to CD14 promoter]	18495781
D002117	Calcitriol	Calcitriol results in increased expression of CD14 mRNA	11158396\|1450407
D002117	Calcitriol	Calcitriol results in increased expression of CD14 protein	11158396\|1150476
D002117	Calcitriol	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]"	20089671
D002117	Calcitriol	parthenolide promotes the reaction [Calcitriol results in increased expression of CD14 protein]	20089671
D002117	Calcitriol	"parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
D002117	Calcitriol	pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
D002117	Calcitriol	"pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
D002117	Calcitriol	salvin promotes the reaction [Calcitriol results in increased expression of CD14 protein]	11504768
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of CD14 mRNA	21592394
D002117	Calcitriol	U 0126 inhibits the reaction [[Cadmium co-treated with Calcitriol] results in increased expression of CD14 protein]	20868229
D002117	Calcitriol	"[Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
D002117	Calcitriol	ZK159222 inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
D002117	Calcitriol	Calcitriol results in increased expression of CD14 mRNA	18495781
D017259	Dimaprit	[Dimaprit binds to and results in increased activity of HRH2 protein] which affects the expression of CD14 protein	14499251
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide results in increased expression of CD14 protein	26036281
D004317	Doxorubicin	Doxorubicin results in increased expression of CD14 mRNA	19915844\|2021121
D004317	Doxorubicin	Razoxane inhibits the reaction [Doxorubicin results in increased expression of CD14 mRNA]	19915844
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased expression of CD14 mRNA"	26539117
D004391	Dust	Dust results in increased expression of CD14 mRNA	17805423
D004610	Ellagic Acid	Ellagic Acid results in decreased expression of CD14 mRNA	20816778
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CD14 mRNA	22079256
D000431	Ethanol	Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of CD14 mRNA]	24239723
D000431	Ethanol	Ethanol results in increased expression of CD14 mRNA	24239723
D000431	Ethanol	Silymarin inhibits the reaction [Ethanol results in increased expression of CD14 mRNA]	24239723
D000431	Ethanol	CD14 gene mutant form results in decreased susceptibility to Ethanol	21309947
D000431	Ethanol	[CD14 protein results in increased susceptibility to Lipopolysaccharides] which affects the susceptibility to Ethanol	21266194
D000431	Ethanol	Ethanol results in increased expression of CD14 mRNA	19167417
D000431	Ethanol	Ethanol results in increased expression of CD14 mRNA	20861358
D004997	Ethinyl Estradiol	Ethinyl Estradiol promotes the reaction [IL1B protein results in increased expression of CD14 mRNA]	12072388
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD14 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of CD14 mRNA	17351261
D011345	Fenofibrate	Fenofibrate results in increased expression of CD14 mRNA	25572481
C000499	ferric oxide	ferric oxide analog results in decreased expression of CD14 mRNA	25086211
C082360	fipronil	fipronil results in increased expression of CD14 mRNA	23962444
D005419	Flavonoids	Flavonoids results in increased expression of CD14 mRNA	18035473
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD14 mRNA	20938992
C021298	ganglioside, GD1a	"CD14 protein affects the reaction [ganglioside, GD1a results in increased secretion of Nitric Oxide]"	16651628
D005732	Gangliosides	CD14 protein affects the reaction [Gangliosides results in increased expression of IL1B mRNA]	16651628
D005732	Gangliosides	CD14 protein affects the reaction [Gangliosides results in increased expression of TNF mRNA]	16651628
D005732	Gangliosides	CD14 protein affects the reaction [Gangliosides results in increased secretion of Nitric Oxide]	16651628
C419708	gefitinib	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C419708	gefitinib	gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]	20226526
C419708	gefitinib	[gefitinib promotes the reaction arsenic trioxide] which results in increased expression of CD14 mRNA	20226526
C419708	gefitinib	SB 203580 inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C007834	genipin	genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	22687549
D019833	Genistein	Genistein results in increased expression of CD14 mRNA	15289156
D005839	Gentamicins	Gentamicins results in increased expression of CD14 mRNA	22061828
D005947	Glucose	CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]	18180316
D005947	Glucose	Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]	18180316
D005947	Glucose	Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
C475739	glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt	"glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt inhibits the reaction [Lipopolysaccharides results in increased localization of CD14 protein]"	21276822
D005978	Glutathione	Glutathione deficiency results in increased expression of CD14 mRNA	15345336
D006118	Griseofulvin	Griseofulvin affects the expression of CD14 mRNA	12735108
D006581	Hexachlorobenzene	Hexachlorobenzene results in increased expression of CD14 mRNA	15159207
D006632	Histamine	Histamine affects the expression of CD14 protein	14499251
D006632	Histamine	HRH2 protein affects the reaction [Histamine affects the expression of CD14 protein]	14499251
D017313	Fenretinide	Fenretinide results in increased expression of CD14 mRNA	28973697
D006854	Hydrocortisone	Hydrocortisone results in decreased expression of CD14 mRNA	17033190
C016517	indole-3-carbinol	indole-3-carbinol affects the expression of CD14 mRNA	21396975
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CD14 mRNA	25613284
D007501	Iron	Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D007501	Iron	Iron deficiency results in increased expression of CD14 protein	20368581
D007501	Iron	pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D007501	Iron	Vitamin D promotes the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D007545	Isoproterenol	Isoproterenol results in increased expression of CD14 mRNA	20003209
D007545	Isoproterenol	Isoproterenol results in increased expression of CD14 mRNA	20211217
C098607	JP8 aviation fuel	JP8 aviation fuel results in increased expression of CD14 protein	17337753
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of CD14 mRNA	25982114
C006552	kaempferol	kaempferol inhibits the reaction [IL32 protein results in increased expression of CD14 mRNA]	28711657
C006552	kaempferol	kaempferol inhibits the reaction [IL32 protein results in increased expression of CD14 protein]	28711657
C014643	lipopeptidophosphoglycan	CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR2 protein]	15910421
C014643	lipopeptidophosphoglycan	CD14 protein promotes the reaction [lipopeptidophosphoglycan results in increased activity of TLR4 protein]	15910421
C482199	lipopolysaccharide, E coli O55-B5	"[lipopolysaccharide, E coli O55-B5 co-treated with FSHB protein] results in decreased expression of CD14 mRNA"	22771338
C482199	lipopolysaccharide, E coli O55-B5	"lipopolysaccharide, E coli O55-B5 results in increased expression of CD14 protein"	20035708
C482199	lipopolysaccharide, E coli O55-B5	"resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CD14 protein]"	20035708
C440499	lipopolysaccharide, Escherichia coli O111 B4	"[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to lipopolysaccharide, Escherichia coli O111 B4"	23680697
C440499	lipopolysaccharide, Escherichia coli O111 B4	"[[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to lipopolysaccharide, Escherichia coli O111 B4] which results in increased expression of CXCL8 mRNA"	23680697
D008070	Lipopolysaccharides	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	[alfacalcidol co-treated with Lipopolysaccharides] results in increased expression of CD14 protein	15946915
D008070	Lipopolysaccharides	BAY 11-7085 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]	18180316
D008070	Lipopolysaccharides	Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]	18180316
D008070	Lipopolysaccharides	Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of CD14 protein	18390722
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 mRNA	18180316
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 protein	12176910\|1818031
D008070	Lipopolysaccharides	[LY96 protein results in increased expression of CD14 mRNA] which results in increased susceptibility to Lipopolysaccharides	20700758
D008070	Lipopolysaccharides	pyrazolanthrone inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	[resveratrol co-treated with Lipopolysaccharides] results in increased expression of CD14 protein	15135313
D008070	Lipopolysaccharides	SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D008070	Lipopolysaccharides	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
D008070	Lipopolysaccharides	[Aflatoxin B1 co-treated with aflatoxin B2] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	22445859
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]	11123339
D008070	Lipopolysaccharides	CD14 protein affects the susceptibility to Lipopolysaccharides	11581577
D008070	Lipopolysaccharides	CD14 protein results in increased susceptibility to Lipopolysaccharides	21266194
D008070	Lipopolysaccharides	[CD14 protein results in increased susceptibility to Lipopolysaccharides] which affects the susceptibility to Ethanol	21266194
D008070	Lipopolysaccharides	genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	22687549
D008070	Lipopolysaccharides	"glutamyl-(2-(((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)carbonyl)-3-((2-(1H-indol-3-yl)ethyl)amino)-3-oxopropyl)-cysteinyl-glycine sodium salt inhibits the reaction [Lipopolysaccharides results in increased localization of CD14 protein]"	21276822
D008070	Lipopolysaccharides	[Lipopolysaccharides co-treated with CD14 protein] results in increased phosphorylation of RELA protein	28411859
D008070	Lipopolysaccharides	[Lipopolysaccharides co-treated with CD14 protein] results in increased secretion of IL6 protein	28411859
D008070	Lipopolysaccharides	Lipopolysaccharides promotes the reaction [LPAR1 protein binds to CD14 protein]	21821728
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of CD14 mRNA	12057914
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 mRNA	10223745\|1097585
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 protein	22445859\|2318295
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased localization of CD14 protein	21276822
D008070	Lipopolysaccharides	methyl-beta-cyclodextrin inhibits the reaction [Lipopolysaccharides promotes the reaction [LPAR1 protein binds to CD14 protein]]	21821728
D008070	Lipopolysaccharides	PCB 180 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	26141388
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of CD14 mRNA	25613284
D008070	Lipopolysaccharides	CD14 protein affects the reaction [Lipopolysaccharides results in increased secretion of Nitric Oxide]	16651628
D008070	Lipopolysaccharides	CD14 protein promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of NOS2 protein]	12133974
D008070	Lipopolysaccharides	CD14 protein promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]	12133974
D008070	Lipopolysaccharides	Lipopolysaccharides binds to CD14 protein	11343695
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 mRNA	16309824\|1871032
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of CD14 protein	18710323
D008070	Lipopolysaccharides	Tretinoin promotes the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	16309824
D008070	Lipopolysaccharides	[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in decreased expression of CD14 mRNA	20816778
D008095	Lithocholic Acid	Benzo(a)pyrene promotes the reaction [Lithocholic Acid results in increased expression of CD14 mRNA]	19244278
D008095	Lithocholic Acid	Lithocholic Acid analog results in increased expression of CD14 mRNA	18180267
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of CD14 mRNA	19244278
C502354	lithocholic acid acetate	lithocholic acid acetate results in increased expression of CD14 mRNA	18180267
C502354	lithocholic acid acetate	lithocholic acid acetate results in increased expression of CD14 protein	15489543
D008550	Melatonin	Melatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of CD14 protein]	28238930
D008550	Melatonin	Melatonin inhibits the reaction [TLR4 protein promotes the reaction [MYD88 protein binds to LY96 protein binds to CD14 protein]]	28238930
D008687	Metformin	Metformin results in increased expression of CD14 protein	26036281
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD14 mRNA	20938992
C108732	methyl-beta-cyclodextrin	methyl-beta-cyclodextrin inhibits the reaction [Lipopolysaccharides promotes the reaction [LPAR1 protein binds to CD14 protein]]	21821728
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of CD14 mRNA	21628967
C008493	methylselenic acid	methylselenic acid results in decreased expression of CD14 mRNA	18548127
C089950	MF59 oil emulsion	MF59 oil emulsion promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in decreased expression of CD14 protein]	18390722
C089950	MF59 oil emulsion	MF59 oil emulsion promotes the reaction [CSF2 protein results in decreased expression of CD14 protein]	18390722
C089950	MF59 oil emulsion	MF59 oil emulsion results in decreased expression of CD14 protein	18390722
D005677	G(M1) Ganglioside	CD14 protein affects the reaction [G(M1) Ganglioside results in increased secretion of Nitric Oxide]	16651628
D009151	Mustard Gas	Mustard Gas results in increased expression of CD14 mRNA	15674843\|1895507
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of CD14 protein"	27475286
D037742	Nanotubes, Carbon	"Nanotubes, Carbon affects the expression of CD14 mRNA"	23845593
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of CD14 mRNA"	25554681\|2562005
D037742	Nanotubes, Carbon	"[Nanotubes, Carbon co-treated with Aluminum Oxide] results in increased secretion of CD14 protein"	25598225
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of CD14 mRNA"	25554681\|2562005
C051752	nefazodone	nefazodone results in increased expression of CD14 mRNA	24136188
D009532	Nickel	Nickel results in decreased expression of CD14 mRNA	23195993
D009532	Nickel	Nickel results in increased expression of CD14 mRNA	24768652\|2558310
C012655	nimesulide	nimesulide results in decreased expression of CD14 mRNA	24136188
D009569	Nitric Oxide	"CD14 protein affects the reaction [ganglioside, GD1a results in increased secretion of Nitric Oxide]"	16651628
D009569	Nitric Oxide	CD14 protein affects the reaction [Gangliosides results in increased secretion of Nitric Oxide]	16651628
D009569	Nitric Oxide	CD14 protein affects the reaction [G(M1) Ganglioside results in increased secretion of Nitric Oxide]	16651628
D009569	Nitric Oxide	CD14 protein affects the reaction [Lipopolysaccharides results in increased secretion of Nitric Oxide]	16651628
D009569	Nitric Oxide	CD14 protein affects the reaction [trisialoganglioside GT1 results in increased secretion of Nitric Oxide]	16651628
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]"	20089671
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein]"	20089671
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CD14 protein"	20089671
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"[Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C570897	NSC668394	NSC668394 results in decreased expression of CD14 mRNA	27137931
C464660	obeticholic acid	obeticholic acid results in decreased expression of CD14 mRNA	27939613
C031004	oligomycin A	oligomycin A results in increased expression of CD14 protein	26036281
D009840	Oligomycins	Oligomycins results in increased expression of CD14 mRNA	10491287
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of CD14 mRNA	25729387
D010126	Ozone	[Ozone co-treated with NOTCH3 gene mutant form] results in increased expression of CD14 mRNA	25658374
D010126	Ozone	Ozone results in increased expression of CD14 mRNA	17095637
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased expression of IL12A mRNA]	11123339
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased expression of IL12B mRNA]	11123339
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased expression of PTGS2 mRNA]	11123339
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK1 protein]	11123339
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK3 protein]	11123339
D017239	Paclitaxel	CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein]	11123339
D017239	Paclitaxel	CD14 protein affects the susceptibility to Paclitaxel	11581577
D017239	Paclitaxel	Paclitaxel results in increased expression of CD14 mRNA	18754875
D000073878	Palm Oil	Palm Oil results in decreased expression of CD14 mRNA	18042831
C016030	pantogab	pantogab results in increased expression of CD14 mRNA	17379144
C084656	paricalcitol	paricalcitol results in increased expression of CD14 protein	12618899
C084656	paricalcitol	[Phosphorus co-treated with paricalcitol] results in increased expression of CD14 mRNA	17715259
C002669	parthenolide	parthenolide promotes the reaction [Calcitriol results in increased expression of CD14 protein]	20089671
C002669	parthenolide	"parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
D052638	Particulate Matter	Particulate Matter results in decreased methylation of CD14 gene	27838013
C410127	PCB 180	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with 2,4,5,2',5'-pentachlorobiphenyl] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C410127	PCB 180	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C410127	PCB 180	"[2,4,5,2',5'-pentachlorobiphenyl co-treated with PCB 180] inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]"	26141388
C410127	PCB 180	PCB 180 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	26141388
D010396	Penicillamine	Penicillamine results in decreased expression of CD14 mRNA	19575532
D010396	Penicillamine	Penicillamine results in increased expression of CD14 mRNA	19575532
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased expression of CD14 mRNA	19162173
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of CD14 protein	26879310
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of CD14 mRNA	19162173
D010634	Phenobarbital	Phenobarbital results in increased expression of CD14 mRNA	19084549
D010758	Phosphorus	[Phosphorus co-treated with paricalcitol] results in increased expression of CD14 mRNA	17715259
C006253	pirinixic acid	pirinixic acid results in increased expression of CD14 mRNA	18301758\|1844570
C006253	pirinixic acid	pirinixic acid results in decreased expression of CD14 mRNA	19162173
D010936	Plant Extracts	Plant Extracts results in increased expression of CD14 mRNA	23557933
D028321	Plant Preparations	Plant Preparations inhibits the reaction [Air Pollutants results in increased expression of CD14 mRNA]	21030725
C060540	polyhexamethyleneguanidine	polyhexamethyleneguanidine results in increased expression of CD14 mRNA	27989595
C443641	poly(propyleneimine)	poly(propyleneimine) analog results in increased expression of CD14 mRNA	16308212
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CD14 mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in decreased expression of CD14 mRNA	22079256
D011374	Progesterone	Progesterone results in decreased expression of CD14 mRNA	21549006
C045950	propiconazole	propiconazole results in increased expression of CD14 mRNA	21278054
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
C008704	pyrithione	"pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C008704	pyrithione	"[Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D011929	Razoxane	Razoxane inhibits the reaction [Doxorubicin results in increased expression of CD14 mRNA]	19915844
C059514	resveratrol	[resveratrol co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CD14 mRNA	16267019
C059514	resveratrol	[resveratrol co-treated with Lipopolysaccharides] results in increased expression of CD14 protein	15135313
C059514	resveratrol	resveratrol results in increased expression of CD14 protein	15135313
C059514	resveratrol	"resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CD14 protein]"	20035708
C059514	resveratrol	resveratrol results in decreased expression of CD14 protein	20035708
C059514	resveratrol	resveratrol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]	15135313
D012402	Rotenone	Rotenone results in increased expression of CD14 mRNA	10491287
C064116	S-(1,1,2,2-tetrafluoroethyl)cysteine	"S-(1,1,2,2-tetrafluoroethyl)cysteine results in decreased expression of CD14 mRNA"	16678137
C018381	salvin	[salvin co-treated with Tretinoin] results in increased expression of CD14 protein	11504768
C018381	salvin	salvin promotes the reaction [Calcitriol results in increased expression of CD14 protein]	11504768
C093642	SB 203580	SB 203580 inhibits the reaction [gefitinib promotes the reaction [arsenic trioxide results in increased expression of CD14 protein]]	20226526
C093642	SB 203580	SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein]	18180316
D012643	Selenium	[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CD14 mRNA	21481475
C078903	seocalcitol	seocalcitol results in increased expression of CD14 mRNA	12040012
D020280	Sertraline	Sertraline results in decreased expression of CD14 mRNA	24865413
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of CD14 mRNA	25351596
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of CD14 mRNA	23221170
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of CD14 mRNA	22431001
D012834	Silver	Silver results in increased expression of CD14 mRNA	27131904
D012838	Silymarin	Silymarin inhibits the reaction [Ethanol results in increased expression of CD14 mRNA]	24239723
D019821	Simvastatin	Simvastatin results in decreased expression of CD14 mRNA	16414398
D012906	Smoke	Smoke results in decreased nitrosation of CD14 protein	21652289
C017947	sodium arsenite	sodium arsenite affects the methylation of CD14 gene	28589171
C017947	sodium arsenite	sodium arsenite results in increased expression of CD14	15710175
C017947	sodium arsenite	sodium arsenite results in increased expression of CD14 mRNA	28595984
C017947	sodium arsenite	sodium arsenite results in increased expression of CD14 mRNA	21134390
C016104	sodium bichromate	sodium bichromate results in decreased expression of CD14 mRNA	17685462
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of CD14 mRNA	27862939
D018038	Sodium Selenite	Sodium Selenite results in increased expression of CD14 mRNA	18175754
D018038	Sodium Selenite	Sodium Selenite results in decreased expression of CD14 mRNA	23274088
D012999	Soman	Soman results in increased expression of CD14 mRNA	19281266
D053260	Soot	Soot results in increased expression of CD14 mRNA	22461453\|2655175
C016766	sulforafan	sulforafan results in increased expression of CD14 mRNA	26833863
C501413	tesaglitazar	tesaglitazar results in decreased expression of CD14 mRNA	21515302
C043062	tesmilifene	tesmilifene results in decreased expression of CD14 protein	11556524
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of CD14 mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of CD14 mRNA	21592394
D013739	Testosterone	Testosterone results in decreased expression of CD14 mRNA	19693291
C000591600	tetrachlorobenzoquinone	Melatonin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of CD14 protein]	28238930
C000591600	tetrachlorobenzoquinone	tetrachlorobenzoquinone results in increased expression of CD14 protein	28238930
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CD14 mRNA	21570461\|2892240
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD14 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CD14 mRNA	11804338\|1187996
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CD14 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CD14 mRNA	21215274
D013755	Tetradecanoylphorbol Acetate	"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein]"	20089671
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of CD14 protein	16430862\|1913503
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CD14 mRNA	25613284
D013853	Thioacetamide	Thioacetamide results in decreased expression of CD14 mRNA	23411599
C009495	titanium dioxide	titanium dioxide affects the expression of CD14 mRNA	23557971
C009495	titanium dioxide	titanium dioxide results in increased expression of CD14 mRNA	27760801
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution affects the expression of CD14 mRNA	20133372
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of CD14 mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of CD14 mRNA	25729387
D014118	Toxins, Biological	"Toxins, Biological affects the expression of CD14 mRNA"	19682533
D014212	Tretinoin	caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of CD14 protein]	16766008
D014212	Tretinoin	[salvin co-treated with Tretinoin] results in increased expression of CD14 protein	11504768
D014212	Tretinoin	Tretinoin promotes the reaction [HOXC4 protein results in increased expression of CD14 mRNA]	16019559
D014212	Tretinoin	Tretinoin results in increased expression of CD14 mRNA	14646600\|1598804
D014212	Tretinoin	Tretinoin results in increased expression of CD14 protein	16766008
D014212	Tretinoin	Tretinoin promotes the reaction [Lipopolysaccharides results in increased expression of CD14 mRNA]	16309824
C012589	trichostatin A	decitabine promotes the reaction [trichostatin A results in increased expression of CD14 mRNA]	18718068
C012589	trichostatin A	trichostatin A results in increased expression of CD14 mRNA	18718068
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of CD14 mRNA	19042947
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in increased expression of CD14 mRNA	17982090
C030665	triphenyltin	triphenyltin results in increased expression of CD14 mRNA	12788061
D014311	Triprolidine	Triprolidine results in decreased expression of CD14 protein	11556524
C016481	trisialoganglioside GT1	CD14 protein affects the reaction [trisialoganglioside GT1 results in increased secretion of Nitric Oxide]	16651628
C057693	troglitazone	troglitazone results in decreased expression of CD14 mRNA	19140230
C057693	troglitazone	troglitazone results in increased expression of CD14 mRNA	25572481
C057693	troglitazone	troglitazone results in increased expression of CD14 protein	12649303
C113580	U 0126	U 0126 inhibits the reaction [[Cadmium co-treated with Calcitriol] results in increased expression of CD14 protein]	20868229
C022884	undecane	undecane results in increased expression of CD14 protein	17337753
D014520	Urethane	Urethane results in decreased expression of CD14 mRNA	28818685
D014580	Ursodeoxycholic Acid	Ursodeoxycholic Acid results in increased expression of CD14 mRNA	15885361
D014640	Vancomycin	Vancomycin results in decreased expression of CD14 mRNA	18930951
D001335	Vehicle Emissions	Vehicle Emissions affects the expression of CD14 mRNA	18192680
D014747	Vinblastine	Vinblastine results in increased expression of CD14 mRNA	20624997
D014750	Vincristine	Vincristine results in increased expression of CD14 mRNA	20624997
C029297	vinylidene chloride	vinylidene chloride results in increased expression of CD14 mRNA	26682919
D014800	Vitallium	[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to Vitallium analog	23680697
D014800	Vitallium	[[TLR4 protein co-treated with LY96 protein co-treated with CD14 protein] results in increased susceptibility to Vitallium analog] which results in increased expression of CXCL8 mRNA	23680697
D014801	Vitamin A	Vitamin A results in increased expression of CD14 mRNA	17033190
D014807	Vitamin D	Vitamin D promotes the reaction [Iron deficiency results in increased expression of CD14 protein]	20368581
D002762	Cholecalciferol	[Cholecalciferol co-treated with TGFB1 protein] results in increased expression of CD14 mRNA	15988048
D002762	Cholecalciferol	Cholecalciferol results in increased expression of CD14 protein	18628207
D002762	Cholecalciferol	PML protein mutant form inhibits the reaction [[Cholecalciferol co-treated with TGFB1 protein] results in increased expression of CD14 mRNA]	15988048
D002762	Cholecalciferol	RAF1 mutant form inhibits the reaction [Cholecalciferol results in increased expression of CD14 protein]	18628207
D002762	Cholecalciferol	RARA protein mutant form inhibits the reaction [[Cholecalciferol co-treated with TGFB1 protein] results in increased expression of CD14 mRNA]	15988048
C511704	xestospongin C	xestospongin C results in increased expression of CD14 protein	23395717
D015032	Zinc	"[Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]"	20089671
C031238	zinc sulfide	[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CD14 mRNA	21481475
C410228	ZK159222	ZK159222 inhibits the reaction [Calcitriol results in increased expression of CD14 protein]	14729647
C088658	zoledronic acid	zoledronic acid results in increased expression of CD14 mRNA	24714768
C088658	zoledronic acid	zoledronic acid results in increased expression of CD14 protein	28871336

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001530	lipopolysaccharide binding	-	IBA	21873635
GO:0001530	lipopolysaccharide binding	-	IDA	12594207
GO:0001847	opsonin receptor activity	-	TAS	2402637
GO:0005515	protein binding	-	IPI	16880211 20860622 22265692 25965346
GO:0016019	peptidoglycan receptor activity	-	TAS	8798531
GO:0070891	lipoteichoic acid binding	-	IDA	12594207
GO:0071723	lipopeptide binding	-	IDA	15294986

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0002224	toll-like receptor signaling pathway	-	TAS	-
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	-	TAS	-
GO:0002756	MyD88-independent toll-like receptor signaling pathway	-	TAS	-
GO:0006898	receptor-mediated endocytosis	-	IEA	-
GO:0006909	phagocytosis	-	TAS	9548256
GO:0006915	apoptotic process	-	TAS	9548256
GO:0006954	inflammatory response	-	IBA	21873635
GO:0006954	inflammatory response	-	IEA	-
GO:0007166	cell surface receptor signaling pathway	-	TAS	8798531
GO:0007249	I-kappaB kinase/NF-kappaB signaling	-	TAS	-
GO:0009408	response to heat	-	IEA	-
GO:0031663	lipopolysaccharide-mediated signaling pathway	-	IBA	21873635
GO:0031663	lipopolysaccharide-mediated signaling pathway	-	IEA	-
GO:0032026	response to magnesium ion	-	IEA	-
GO:0032481	positive regulation of type I interferon production	-	IBA	21873635
GO:0032481	positive regulation of type I interferon production	-	IEA	-
GO:0032729	positive regulation of interferon-gamma production	-	IBA	21873635
GO:0032729	positive regulation of interferon-gamma production	-	ISS	-
GO:0032760	positive regulation of tumor necrosis factor production	-	IDA	12594207 15294986
GO:0032760	positive regulation of tumor necrosis factor production	-	IMP	8612135
GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway	-	TAS	-
GO:0034142	toll-like receptor 4 signaling pathway	-	IBA	21873635
GO:0034142	toll-like receptor 4 signaling pathway	-	ISS	-
GO:0034142	toll-like receptor 4 signaling pathway	-	TAS	-
GO:0034612	response to tumor necrosis factor	-	IEA	-
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	-	TAS	-
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	-	TAS	-
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	-	TAS	-
GO:0043312	neutrophil degranulation	-	TAS	-
GO:0045087	innate immune response	-	IEA	-
GO:0045471	response to ethanol	-	IEA	-
GO:0045807	positive regulation of endocytosis	-	IEA	-
GO:0050715	positive regulation of cytokine secretion	-	IBA	21873635
GO:0051602	response to electrical stimulus	-	IEA	-
GO:0070266	necroptotic process	-	TAS	-
GO:0071219	cellular response to molecule of bacterial origin	-	IDA	15039339
GO:0071222	cellular response to lipopolysaccharide	-	IBA	21873635
GO:0071222	cellular response to lipopolysaccharide	-	IDA	12594207
GO:0071222	cellular response to lipopolysaccharide	-	IMP	8612135
GO:0071223	cellular response to lipoteichoic acid	-	IDA	12594207
GO:0071726	cellular response to diacyl bacterial lipopeptide	-	IDA	16880211
GO:0071727	cellular response to triacyl bacterial lipopeptide	-	IDA	16880211
GO:0097190	apoptotic signaling pathway	-	TAS	-
GO:1901224	positive regulation of NIK/NF-kappaB signaling	-	IBA	21873635
GO:1901224	positive regulation of NIK/NF-kappaB signaling	-	IDA	15294986
GO:2000484	positive regulation of interleukin-8 secretion	-	IBA	21873635
GO:2000484	positive regulation of interleukin-8 secretion	-	IMP	15039339

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	TAS	-
GO:0005615	extracellular space	-	HDA	16502470
GO:0005794	Golgi apparatus	-	IDA	16880211
GO:0005886	plasma membrane	-	TAS	-
GO:0009897	external side of plasma membrane	-	IBA	21873635
GO:0009986	cell surface	-	IBA	21873635
GO:0010008	endosome membrane	-	TAS	-
GO:0030667	secretory granule membrane	-	TAS	-
GO:0031362	anchored component of external side of plasma membrane	-	IDA	3385210
GO:0045121	membrane raft	-	IBA	21873635
GO:0045121	membrane raft	-	IDA	16880211
GO:0046696	lipopolysaccharide receptor complex	-	IBA	21873635
GO:0046696	lipopolysaccharide receptor complex	-	IDA	11274165
GO:0070062	extracellular exosome	-	HDA	19056867 19199708 23533145

KEGG ID	KEGG Term
hsa04010	MAPK signaling pathway
hsa04145	Phagosome
hsa04620	Toll-like receptor signaling pathway
hsa04640	Hematopoietic cell lineage
hsa04810	Regulation of actin cytoskeleton
hsa05130	Pathogenic Escherichia coli infection
hsa05146	Amoebiasis

Reactome ID	Reactome Term	Evidence
R-HSA-109581	Apoptosis	TAS
R-HSA-1236974	ER-Phagosome pathway	TAS
R-HSA-1236975	Antigen processing-Cross presentation	TAS
R-HSA-1280218	Adaptive Immune System	TAS
R-HSA-140534	Ligand-dependent caspase activation	TAS
R-HSA-1643685	Disease	TAS
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	TAS
R-HSA-166020	Transfer of LPS from LBP carrier to CD14	TAS
R-HSA-166058	MyD88:Mal cascade initiated on plasma membrane	TAS
R-HSA-166166	MyD88-independent TLR4 cascade	TAS
R-HSA-168138	Toll Like Receptor 9 (TLR9) Cascade	TAS
R-HSA-168164	Toll Like Receptor 3 (TLR3) Cascade	TAS
R-HSA-168179	Toll Like Receptor TLR1:TLR2 Cascade	TAS
R-HSA-168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	TAS
R-HSA-168188	Toll Like Receptor TLR6:TLR2 Cascade	TAS
R-HSA-168249	Innate Immune System	TAS
R-HSA-168256	Immune System	TAS
R-HSA-168898	Toll-Like Receptors Cascades	TAS
R-HSA-181438	Toll Like Receptor 2 (TLR2) Cascade	TAS
R-HSA-2562578	TRIF-mediated programmed cell death	TAS
R-HSA-5260271	Diseases of Immune System	TAS
R-HSA-5357769	Caspase activation via extrinsic apoptotic signalling pathway	TAS
R-HSA-5357801	Programmed Cell Death	TAS
R-HSA-5602358	Diseases associated with the TLR signaling cascade	TAS
R-HSA-5602498	MyD88 deficiency (TLR2/4)	TAS
R-HSA-5603041	IRAK4 deficiency (TLR2/4)	TAS
R-HSA-5686938	Regulation of TLR by endogenous ligand	TAS
R-HSA-6798695	Neutrophil degranulation	TAS
R-HSA-9014325	TICAM1,TRAF6-dependent induction of TAK1 complex	TAS
R-HSA-936964	Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	TAS
R-HSA-937041	IKK complex recruitment mediated by RIP1	TAS
R-HSA-937061	TRIF(TICAM1)-mediated TLR4 signaling	TAS
R-HSA-937072	TRAF6-mediated induction of TAK1 complex within TLR4 complex	TAS
R-HSA-975138	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	TAS
R-HSA-975155	MyD88 dependent cascade initiated on endosome	TAS
R-HSA-975163	IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	TAS
R-HSA-983169	Class I MHC mediated antigen processing & presentation	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
21439805	Toll-like receptor expression in smokers with and without COPD. (2011 Aug)	von Scheele I	Respir Med
28463881	Emphysema and soluble CD14 are associated with pulmonary nodules in HIV-infected patients: implications for lung cancer screening. (2017 Jul 31)	Triplette M	AIDS
27633722	Red Wine Prevents the Acute Negative Vascular Effects of Smoking. (2017 Jan)	Schwarz V	Am J Med
28302109	Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers. (2017 Mar 16)	LeVan TD	Respir Res
18157711	Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. (2009 Jan)	Banerjee I	J Thromb Thrombolysis
11257272	A prospective evaluation of the CD14 C(-260)T gene polymorphism and the risk of myocardial infarction. (2001 Feb 15)	Zee RY	Atherosclerosis
8586328	[Characterization of bronchoalveolar space cells in pulmonary sarcoidosis]. (1994)	Czarnobilska E	Folia Med Cracov
22399514	Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production. (2012 May)	Gillespie EF	J Clin Endocrinol Metab
16246938	CD14 and TLR4 gene polymorphisms in adult periodontitis. (2005 Nov)	Laine ML	J Dent Res
15289211	Chronic alcoholism causes deleterious conditioning of innate immunity. (2004 Sep-Oct)	Frank J	Alcohol Alcohol
12480498	The relation of aggression, hostility, and anger to lipopolysaccharide-stimulated tumor necrosis factor (TNF)-alpha by blood monocytes from normal men. (2002 Dec)	Suarez EC	Brain Behav Immun
8181314	Expression of surface markers on alveolar macrophages from symptomatic patients with HIV infection as detected by flow cytometry. (1994 May)	Wasserman K	Chest
1892301	T cell subsets in healthy black smokers and nonsmokers. Evidence for ethnic group as an important response modifier. (1991 Sep)	Tollerud DJ	Am Rev Respir Dis
27019552	Systemic Immune Activation Profiles of HIV-1 Subtype C-Infected Children and Their Mothers. (2016)	Makhubele TG	Mediators Inflamm
27693003	Electronic cigarettes increase endothelial progenitor cells in the blood of healthy volunteers. (2016 Dec)	Antoniewicz L	Atherosclerosis
26474031	Correlation Between High-Density Lipoprotein and Monocyte Subsets in Patients with Stable Coronary Heart Disease. (2015 Jun 2)	Jiang S	Med Sci Monit
25479137	Blockade of PD1 and TIM3 restores innate and adaptive immunity in patients with acute alcoholic hepatitis. (2015 Mar)	Markwick LJ	Gastroenterology
28434814	Novel protein biomarkers associated with coronary artery disease in statin-treated patients with familial hypercholesterolemia. (2017 May - Jun)	Bos S	J Clin Lipidol
15292769	Promoter polymorphism of the gene for CD14 receptor is not associated with sub-clinical carotid atherosclerosis in a community population. (2004 Aug)	Hung J	Eur J Cardiovasc Prev Rehabil
15257175	CD14 C(-260)T gene polymorphism, circulating soluble CD14 levels and arteriosclerosis. (2004 Aug)	Amar J	J Hypertens
27343547	Inflammatory Biomarkers and Mortality Risk Among HIV-Suppressed Men: A Multisite Prospective Cohort Study. (2016 Oct 1)	Wada NI	Clin Infect Dis
16771785	Soluble CD14 at 2 yr of age: gender-related effects of tobacco smoke exposure, recurrent infections and atopic diseases. (2006 Jun)	Lodrup Carlsen KC	Pediatr Allergy Immunol
24594088	Circulating endothelial progenitor cells as markers for severity of ischemic chronic heart failure. (2014 Jun)	Berezin AE	J Card Fail
11935032	A prospective evaluation of the CD14 and CD18 gene polymorphisms and risk of stroke. (2002 Apr)	Zee RY	Stroke
17086603	Association of rheumatoid arthritis with ergothioneine levels in red blood cells: a case control study. (2006 Nov)	Taubert D	J Rheumatol
27613907	Secondhand Tobacco Smoke Exposure Associations With DNA Methylation of the Aryl Hydrocarbon Receptor Repressor. (2017 Apr 1)	Reynolds LM	Nicotine Tob Res
11852118	Lymphocyte phenotype analysis and chromosome aberration frequency of workers occupationally exposed to styrene, benzene, polycyclic aromatic hydrocarbons or mixed solvents. (2002 Apr 22)	Biro A	Immunol Lett
29287311	Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. (2018 Apr)	Mok A	Arthritis Rheumatol
27153514	Semen leukocytes and oxidative-dependent DNA damage of spermatozoa in male partners of subfertile couples with no symptoms of genital tract infection. (2016 Sep)	Micillo A	Andrology
19218648	Role of bronchoalveolar lavage in the initial diagnosis of smoking-related interstitial lung diseases. (2008 Dec)	Domagala-Kulawik J	J Physiol Pharmacol
22955940	Local inflammation is associated with aortic thrombus formation in abdominal aortic aneurysms. Relationship to clinical risk factors. (2012 Nov)	Sagan A	Thromb Haemost
9373224	Pre-operative neutrophil and monocyte activation state predicts post-operative neutrophil and monocyte function. (1997 Oct)	Barry MC	Eur J Surg
12624278	Promoter polymorphism in the endotoxin receptor (CD14) is associated with increased carotid atherosclerosis only in smokers: the Carotid Atherosclerosis Progression Study (CAPS). (2003 Mar)	Risley P	Stroke
15138625	Paradoxically decreased intracellular collagenase activity in macrophages from bronchoalveolar lavage fluid in current smokers and patients with obstructive ventilatory disorder. (2004 Jun)	Hakoda Y	Int J Mol Med
27144407	Cord Blood Soluble CD14 Predicts Wheeze and Prolonged Cough in Young Children: The PATCH Study. (2016)	Su KW	Int Arch Allergy Immunol
19165564	Chronic systemic inflammation accompanies impaired ventricular diastolic function, detected by Doppler imaging, in patients with newly diagnosed systolic heart failure (Hellenic Heart Failure Study). (2009 Jan)	Chrysohoou C	Heart Vessels
21239386	TLR-4+ peripheral blood monocytes and cardiovascular events in patients with chronic kidney disease--a prospective follow-up study. (2011 Apr)	Lorenzen JM	Nephrol Dial Transplant
19244278	The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. (2009 May)	Matsunawa M	Toxicol Sci
19010986	Lipopolysaccharide-binding protein and CD14 are increased in the bronchoalveolar lavage fluid of smokers. (2009 Feb)	Regueiro V	Eur Respir J
12849800	Blood leukocyte subsets are modulated in patients with endometriosis. (2003 Jul)	Gagne D	Fertil Steril
16423536	Platelet-monocyte pro-coagulant interactions in on-pump coronary surgery. (2006 Mar)	Weerasinghe A	Eur J Cardiothorac Surg
26957492	Association of cytokine gene polymorphisms and risk factors with otitis media proneness in children. (2016 Jun)	Miljanovic O	Eur J Pediatr
2570147	Decreased levels of circulating CD4+ T lymphocytes during normal human pregnancy. (1989 May)	Castilla JA	J Reprod Immunol
23748423	Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling. (2013 Aug 15)	Zhou MS	Am J Physiol Heart Circ Physiol
27882430	Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials. (2017 Jan)	Contreras A	Basic Res Cardiol
11223444	Levels of expression of Fcgamma receptor IIA (CD32) are decreased on peripheral blood monocytes in patients with severe atherosclerosis. (2001 Mar)	Pfeiffer JR	Atherosclerosis
19675120	Altered innate immune response in farmers and smokers. (2010 Feb)	Sahlander K	Innate Immun
15472098	Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers. (2004 Nov)	Jerrard-Dunne P	Stroke
16297172	The immune responses to human and microbial heat shock proteins in periodontal disease with and without coronary heart disease. (2005 Dec)	Hasan A	Clin Exp Immunol
27033574	[Effect of CD14 promoter variants on the susceptibility to laryngeal cancer]. (2016 Mar)	Yang L	Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
16295318	Ethanol-induced dysfunction of hepatocytes and leukocytes in patients without liver failure. (2004 Jan-Jun)	Gheorghiu M	Roum Arch Microbiol Immunol
12684293	The cellular composition and macrophage phenotype in induced sputum in smokers and ex-smokers with COPD. (2003 Apr)	Domagala-Kulawik J	Chest
25430025	[Identification and clinical significance of myeloid-derived suppressor cells in peripheral blood of small-cell lung cancer patients]. (2014 Aug)	Cheng Y	Zhonghua Zhong Liu Za Zhi
14639920	[Ethanol changes sensitivity of Kupffer cells to endotoxin]. (2003 Oct)	Yamashina S	Nihon Arukoru Yakubutsu Igakkai Zasshi
16844729	Innate immune activation in neutrophilic asthma and bronchiectasis. (2007 Mar)	Simpson JL	Thorax
17436151	CD14 gene polymorphism 159C/T in a group of patients with coronary artery disease from a population with high morbidity of cardiovascular diseases. (2007 Mar)	Rechcinski T	Kardiol Pol
12011764	Is the CD14 receptor gene a marker for smoking dependence? (2002 May)	Hubacek J	Med Sci Monit
27156912	Cadmium exposure as measured in blood in relation to macrophage density in symptomatic atherosclerotic plaques from human carotid artery. (2016 Jun)	Fagerberg B	Atherosclerosis
25689051	Beryllium increases the CD14(dim)CD16+ subset in the lung of chronic beryllium disease. (2015)	Li L	PLoS One
17973582	[Life-threatening acute lower gastrointestinal bleeding in patients with Crohn's disease]. (2007 Jul)	Barreiro de Acosta M	Rev Esp Enferm Dig
2786361	The effects of cigarette smoking on T cell subsets. A population-based survey of healthy caucasians. (1989 Jun)	Tollerud DJ	Am Rev Respir Dis
19361972	Influence of C-159T SNP of the CD14 gene promoter on lung function in smokers. (2009 Sep)	Zhou H	Respir Med
12928151	Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects. (2003 Aug)	Wu MM	Environ Health Perspect
28906511	Association of Cytokine Gene Polymorphism with Peri-implantitis Risk. (2017 Sep/Oct)	Petkovic-Curcin A	Int J Oral Maxillofac Implants
26629252	Correlation between high density lipoprotein and monocyte subpopulations among stable coronary atherosclerotic heart disease patients. (2015)	Yang RH	Int J Clin Exp Med
24454004	Effects of polymorphisms of innate immunity genes and environmental factors on the risk of noncardia gastric cancer. (2013 Dec)	Kim J	Cancer Res Treat
16907910	Different inflammatory cell pattern and macrophage phenotype in chronic obstructive pulmonary disease patients, smokers and non-smokers. (2006 Sep)	Lofdahl JM	Clin Exp Immunol
23349936	Determinants of serum concentrations of lipopolysaccharide-binding protein (LBP) in the adult population: the role of obesity. (2013)	Gonzalez-Quintela A	PLoS One
27242060	Alcohol use predicts elevation in inflammatory marker soluble CD14 in men living with HIV. (2016 Nov)	Monnig MA	AIDS Care
17653770	Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease. (2007 Nov)	Chen Z	Hum Genet
17617027	High-sensitivity C-reactive protein concentration in patients with myocardial infarction-environmental factors, and polymorphisms in interleukin-10 and CD14 genes. (2007)	Lorenzova A	Clin Chem Lab Med
8870707	Chronic smoke exposure alters the phenotype pattern and the metabolic response in human alveolar macrophages. (1996 Oct)	Skold CM	Clin Exp Immunol
27355513	Plasma CXCL10, sCD163 and sCD14 Levels Have Distinct Associations with Antiretroviral Treatment and Cardiovascular Disease Risk Factors. (2016)	Castley A	PLoS One
24401216	Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. (2014 Jan)	Barbour JD	Atherosclerosis
29791013	Frontline Science: Buprenorphine decreases CCL2-mediated migration of CD14(+) CD16(+) monocytes. (2018 May 23)	Jaureguiberry-Bravo M	J Leukoc Biol
23748193	An association between adiposity and serum levels of macrophage inflammatory protein-1alpha and soluble CD14 in HIV-infected adults: results from a cross-sectional study. (2013)	Koethe JR	Antivir Ther
12679473	CD14 monocyte receptor, involved in the inflammatory cascade, and insulin sensitivity. (2003 Apr)	Fernandez-Real JM	J Clin Endocrinol Metab
18475731	Cell surface antigen expression by peripheral blood monocytes in allergic asthma: results of 2.5 years therapy with inhaled beclomethasone dipropionate. (1996)	Slieker WA	Mediators Inflamm
23046822	Clinical application of human beta-defensin and CD14 gene polymorphism in evaluating the status of chronic inflammation. (2012 Sep 19)	Loo WT	J Transl Med
19046305	Impact of genetic variants of CD14 and TLR4 on subgingival periodontopathogens. (2008 Dec)	Schulz S	Int J Immunogenet
9926990	Even moderate cigarette smoking influences the pattern of circulating monocytes and the concentration of sICAM-1. (1998 Dec)	Bergmann S	Respir Physiol
24651679	Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection. (2014 May)	Shaked I	Arterioscler Thromb Vasc Biol
17072032	Expression of macrophage surface markers in induced sputum of patients with chronic obstructive pulmonary disease. (2006 Sep)	Domagala-Kulawik J	J Physiol Pharmacol
26181818	Elevated Soluble CD14 and Lower D-Dimer Are Associated With Cigarette Smoking and Heavy Episodic Alcohol Use in Persons Living With HIV. (2015 Dec 1)	Cioe PA	J Acquir Immune Defic Syndr
12390313	Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells. (2002 Nov)	Woollard KJ	Clin Exp Immunol
25733587	Increased systemic immune activation and inflammatory profile of long-term HIV-infected ART-controlled patients is related to personal factors, but not to markers of HIV infection severity. (2015)	Bastard JP	J Antimicrob Chemother
24842313	Tobacco smoking increases immune activation and impairs T-cell function in HIV infected patients on antiretrovirals: a cross-sectional pilot study. (2014)	Valiathan R	PLoS One
16520888	ALDH2 polymorphisms and bone mineral density in an elderly Japanese population. (2006)	Yamaguchi J	Osteoporos Int
24776844	Associations between functional polymorphisms in the NFkappaB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease. (2014 Dec)	Bank S	Pharmacogenomics J
17043800	Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males. (2007 Feb)	Bonaterra GA	J Mol Med (Berl)
27919931	Low MT-CO1 in Monocytes and Microvesicles Is Associated With Outcome in Patients With Coronary Artery Disease. (2016 Dec 5)	Holvoet P	J Am Heart Assoc
18727828	Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study. (2008 Aug 26)	Cole JW	Thromb J
29140561	Interaction among smoking status, single nucleotide polymorphisms and markers of systemic inflammation in healthy individuals. (2018 May)	Luetragoon T	Immunology
26509359	Unhealthy Alcohol Use is Associated with Monocyte Activation Prior to Starting Antiretroviral Therapy. (2015 Dec)	Carrico AW	Alcohol Clin Exp Res
19795323	CD14 promoter polymorphism (- 159C-->t) is not associated with myocardial infarction or coronary artery disease in patients with assumed high genetic risk. (2009 Oct)	Haberbosch W	Thorac Cardiovasc Surg