| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| CDY2A | 0.938 |
| OR5F1 | 0.938 |
| TSPY3 | 0.938 |
| OR5M1 | 0.938 |
| OR5T2 | 0.938 |
| KRTAP6-2 | 0.938 |
| OR4C12 | 0.938 |
| KRTAP27-1 | 0.938 |
| OR5W2 | 0.938 |
| MAGEB5 | 0.938 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| ADCY2 | -0.267 |
| SLC1A4 | -0.261 |
| TMEM221 | -0.245 |
| FUT9 | -0.242 |
| B3GALT1 | -0.241 |
| CADM1 | -0.241 |
| NTSR2 | -0.234 |
| LGI1 | -0.234 |
| CHST1 | -0.234 |
| CORO2B | -0.233 |
| ID | Drug Name | Drug Type | CAS Num | Status | Role |
|---|---|---|---|---|---|
| DB00786 | Marimastat | Small Molecule | 154039-60-8 | Approved|Investigational | Target |
| DB08271 | N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID | Small Molecule | Experimental | Target |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased methylation of MMP20 gene | 27153756 |
| D004958 | Estradiol | [bisphenol A co-treated with Estradiol] results in increased expression of MMP20 mRNA | 26496021 |
| D004958 | Estradiol | Estradiol results in increased expression of MMP20 mRNA | 26945725 |
| C006780 | bisphenol A | [bisphenol A co-treated with Estradiol] results in increased expression of MMP20 mRNA | 26496021 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of MMP20 mRNA | 25181051 |
| D005473 | Fluoxetine | Fluoxetine results in decreased expression of MMP20 mRNA | 21083617 |
| D012701 | Serotonin | Serotonin results in decreased expression of MMP20 mRNA | 21083617 |
| D016226 | Phosphorus, Dietary | "Phosphorus, Dietary affects the expression of MMP20 mRNA" | 17651324 |
| D017632 | Asbestos, Serpentine | "Asbestos, Serpentine results in increased expression of MMP20 mRNA" | 21514415 |
| D012969 | Sodium Fluoride | Sodium Fluoride results in decreased secretion of MMP20 protein | 21626649 |
| D013853 | Thioacetamide | Thioacetamide results in increased expression of MMP20 mRNA | 23411599 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of MMP20 mRNA | 28001369 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0004222 | metalloendopeptidase activity | - | IDA | 9398237 |
| GO:0004252 | serine-type endopeptidase activity | - | TAS | - |
| GO:0005515 | protein binding | - | IPI | 18434575 |
| GO:0008270 | zinc ion binding | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0006508 | proteolysis | - | IEA | - |
| GO:0022617 | extracellular matrix disassembly | - | IEA | - |
| GO:0030163 | protein catabolic process | - | IEA | - |
| GO:0030574 | collagen catabolic process | - | TAS | - |
| GO:0070173 | regulation of enamel mineralization | - | TAS | 18434575 |
| GO:0097186 | amelogenesis | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0005576 | extracellular region | - | TAS | - |
| GO:0005615 | extracellular space | - | TAS | 9398237 |
| GO:0031012 | extracellular matrix | - | IEA | - |
| KEGG ID | KEGG Term |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-1442490 | Collagen degradation | TAS |
| R-HSA-1474228 | Degradation of the extracellular matrix | IEA |
| R-HSA-1474228 | Degradation of the extracellular matrix | TAS |
| R-HSA-1474244 | Extracellular matrix organization | IEA |
| R-HSA-1474244 | Extracellular matrix organization | TAS |
| R-HSA-1474290 | Collagen formation | TAS |
| R-HSA-2022090 | Assembly of collagen fibrils and other multimeric structures | TAS |
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 28266114 | Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. (2017 Mar) | Chapple IL | J Clin Periodontol |