| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| C9orf135 | 0.551 |
| CALCR | 0.531 |
| SPARC | 0.528 |
| IGF2BP2 | 0.524 |
| AGTR1 | 0.521 |
| PIRT | 0.521 |
| CCDC140 | 0.515 |
| C1QL4 | 0.511 |
| CRNDE | 0.507 |
| GSC | 0.503 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| TBR1 | -0.365 |
| SLC22A9 | -0.355 |
| FEZF2 | -0.332 |
| RORB | -0.331 |
| KCNA2 | -0.33 |
| FUT9 | -0.329 |
| EXTL1 | -0.324 |
| NEUROD2 | -0.323 |
| IPCEF1 | -0.319 |
| SKIDA1 | -0.316 |
| ID | Drug Name | Drug Type | CAS Num | Status | Role |
|---|---|---|---|---|---|
| DB00130 | L-Glutamine | Small Molecule | 56-85-9 | Approved|Investigational|Nutraceutical | Enzyme |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of TGM5 mRNA | 17562736 |
| D000117 | Acetylglucosamine | Acetylglucosamine results in increased expression of TGM5 mRNA | 18047607 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of TGM5 mRNA | 21641981|2210060 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in increased expression of TGM5 mRNA" | 25351596 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of TGM5 mRNA | 21632981|2187194 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of TGM5 mRNA | 25181051 |
| C480342 | clothianidin | clothianidin results in decreased expression of TGM5 mRNA | 29044138 |
| D002945 | Cisplatin | Cisplatin results in increased expression of TGM5 mRNA | 27594783 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of TGM5 mRNA | 26752646 |
| D058185 | Magnetite Nanoparticles | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of TGM5 mRNA | 26378955 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of TGM5 mRNA | 23103053 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of TGM5 mRNA | 23811191 |
| C059514 | resveratrol | resveratrol results in increased expression of TGM5 mRNA | 16985168 |
| D004113 | Succimer | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of TGM5 mRNA | 26378955 |
| C061133 | tamibarotene | tamibarotene results in increased expression of TGM5 mRNA | 15498508 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of TGM5 mRNA | 16985168|2315218 |
| D014212 | Tretinoin | Tretinoin results in increased expression of TGM5 mRNA | 15498508 |
| C013320 | tris(2-butoxyethyl) phosphate | tris(2-butoxyethyl) phosphate affects the expression of TGM5 mRNA | 29024780 |
| D014520 | Urethane | Urethane results in decreased expression of TGM5 mRNA | 28818685 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in decreased methylation of TGM5 gene | 25560391 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0003810 | protein-glutamine gamma-glutamyltransferase activity | - | TAS | - |
| GO:0046872 | metal ion binding | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0006464 | cellular protein modification process | - | TAS | 9452468 |
| GO:0008544 | epidermis development | - | TAS | 9452468 |
| GO:0018149 | peptide cross-linking | - | IEA | - |
| GO:0070268 | cornification | - | TAS | - |
| KEGG ID | KEGG Term |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-1266738 | Developmental Biology | TAS |
| R-HSA-6805567 | Keratinization | TAS |
| R-HSA-6809371 | Formation of the cornified envelope | TAS |
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 24518713 | Association between TGM5, PPAP2B and PSMA4 polymorphisms and NSCLC in never-smoking Chinese population. (2013 Oct-Dec) | Yongjun Zhang MM | J Cancer Res Ther |