Gene: SNAP29

9342
CEDNIK|SNAP-29
synaptosome associated protein 29
protein-coding
22q11.21
Ensembl:ENSG00000099940 MIM:604202 Vega:OTTHUMG00000150765 UniprotKB:O95721
NG_012152.1
PubMed
0   ANCO-SNPs
AD
1   
5.541e-1 (AD)  5.007e-1 (ND)   (Frontal_Cortex)
2.870e-1 (AD)  3.379e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADIPOR10.892
PPP1R80.883
RAB100.88
TSN0.877
GLO10.876
SAR1A0.875
TMED20.875
COPZ10.874
CAP10.872
CANX0.872

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.755
OR4F29-0.729
MTRNR2L6-0.243
MS4A1-0.237
IFNG-0.233
MTRNR2L9-0.228
PPBP-0.218
NANOGNB-0.213
OR4F16-0.212
C8orf74-0.206

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of SNAP29 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SNAP29 mRNA"21346803
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of SNAP29 mRNA"25380136
D000082AcetaminophenAcetaminophen results in increased expression of SNAP29 mRNA22230336
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SNAP29 mRNA16483693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SNAP29 mRNA22228805
C006780bisphenol Abisphenol A affects the expression of SNAP29 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of SNAP29 mRNA25181051
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SNAP29 gene20938992
C018021cobaltous chloridecobaltous chloride results in increased expression of SNAP29 mRNA19376846
D016572CyclosporineCyclosporine results in increased expression of SNAP29 mRNA19770486
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of SNAP29 mRNA23914054
D002945CisplatinCisplatin results in increased expression of SNAP29 protein16803524
D004041Dietary FatsDietary Fats affects the expression of SNAP29 mRNA19680557
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SNAP29 mRNA17942748
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of SNAP29 mRNA23649840
D005411Flame RetardantsFlame Retardants results in increased expression of SNAP29 protein18550172
D005472FluorouracilFluorouracil results in increased expression of SNAP29 protein16803524
D005485FlutamideFlutamide results in increased expression of SNAP29 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SNAP29 gene20938992
D008713MethimazoleMethimazole results in increased expression of SNAP29 mRNA22504374
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SNAP29 gene20938992
D008727MethotrexateMethotrexate affects the expression of SNAP29 mRNA18502557
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of SNAP29 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SNAP29 mRNA23649840
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of SNAP29 mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of SNAP29 mRNA25380136
C051752nefazodonenefazodone results in increased expression of SNAP29 mRNA24136188
C028007nickel monoxidenickel monoxide results in increased expression of SNAP29 mRNA19167457
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of SNAP29 protein18550172
C006253pirinixic acidpirinixic acid results in increased expression of SNAP29 mRNA18301758
D011441PropylthiouracilPropylthiouracil results in increased expression of SNAP29 mRNA22504374
C502851quinocetonequinocetone results in decreased expression of SNAP29 protein27046791
D012999SomanSoman results in decreased expression of SNAP29 mRNA19281266
C013698tallowtallow affects the expression of SNAP29 mRNA19680557
C004648testosterone enanthatetestosterone enanthate affects the expression of SNAP29 mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SNAP29 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SNAP29 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SNAP29 mRNA19770486
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of SNAP29 mRNA19042947
D014635Valproic AcidValproic Acid results in increased expression of SNAP29 mRNA23179753|2800136
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SNAP29 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005484SNAP receptor activity-IBA21873635  
GO:0005484SNAP receptor activity-TAS10839363  
GO:0005515protein binding-IPI23217709  25416956  25419848  26359495  
GO:0019905syntaxin binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006887exocytosis-IBA21873635  
GO:0006887exocytosis-TAS10839363  
GO:0006903vesicle targeting-TAS9852078  
GO:0006906vesicle fusion-IBA21873635  
GO:0015031protein transport-IEA-  
GO:0016082synaptic vesicle priming-IBA21873635  
GO:0016240autophagosome membrane docking-IDA25686604  
GO:0031629synaptic vesicle fusion to presynaptic active zone membrane-IBA21873635  
GO:0043312neutrophil degranulation-TAS-  
GO:0060271cilium assembly-IMP25686250  
GO:0061025membrane fusion-TAS10839363  
GO:0097352autophagosome maturation-IMP23217709  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-TAS-  
GO:0000421autophagosome membrane-IEA-  
GO:0005654nucleoplasm-IDA-  
GO:0005737cytoplasm-IDA25468996  
GO:0005776autophagosome-ISS-  
GO:0005813centrosome-IDA-  
GO:0005829cytosol-IDA-  
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-TAS-  
GO:0020018ciliary pocket membrane-IDA25686250  
GO:0031201SNARE complex-IBA21873635  
GO:0031201SNARE complex-IDA23217709  
GO:0035577azurophil granule membrane-TAS-  
GO:0098793presynapse-IEA-  
KEGG ID KEGG Term
hsa04130SNARE interactions in vesicular transport
Reactome ID Reactome Term Evidence
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-199991Membrane TraffickingTAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-6811438Intra-Golgi trafficTAS
R-HSA-6811442Intra-Golgi and retrograde Golgi-to-ER trafficTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27490364High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model. (2016 Aug)Lo CLPLoS Genet