Gene: ZNF264

9422
-
zinc finger protein 264
protein-coding
19q13.43
Ensembl:ENSG00000083844 MIM:604668 Vega:OTTHUMG00000183104 UniprotKB:O43296
NG_016432.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.331e-1 (AD)  5.986e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg12096988chr19:57702809ZNF2646.750e-13Alcohol consumption per day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PHC30.84
RNF1690.832
CDK120.795
USP370.792
AGO20.786
DENND4A0.779
ZNF8080.778
ZNF810.775
ATF7IP0.772
SHPRH0.769

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NEU4-0.272
OR4F5-0.25
RBM34-0.243
ALG1L-0.24
OR4F29-0.235
REN-0.235
HES5-0.23
KLRC2-0.225
C8G-0.224
NANOGNB-0.216

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C447119bazedoxifenebazedoxifene results in increased expression of ZNF264 mRNA19914376
C584509C646 compoundC646 compound results in increased expression of ZNF264 mRNA26191083
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of ZNF264 mRNA20971185
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of ZNF264 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of ZNF264 mRNA27392435
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of ZNF264 mRNA23649840
D004397FonofosFonofos results in increased methylation of ZNF264 promoter22847954
D005557FormaldehydeFormaldehyde results in decreased expression of ZNF264 mRNA20655997
C492448ICG 001ICG 001 results in increased expression of ZNF264 mRNA26191083
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of ZNF264 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of ZNF264 mRNA27392435
D007854LeadLead results in decreased expression of ZNF264 mRNA19921347
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZNF264 mRNA23649840
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of ZNF264 mRNA20971185
D010278ParathionParathion results in increased methylation of ZNF264 promoter22847954
D010936Plant ExtractsPlant Extracts results in increased expression of ZNF264 mRNA23557933
D012643SeleniumSelenium results in decreased expression of ZNF264 mRNA19244175
C012568terbufosterbufos results in increased methylation of ZNF264 promoter22847954
C004648testosterone enanthatetestosterone enanthate affects the expression of ZNF264 mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZNF264 mRNA22574217
D014520UrethaneUrethane results in increased expression of ZNF264 mRNA28818685
D014635Valproic AcidValproic Acid results in decreased expression of ZNF264 mRNA28001369

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27113098CPEB4 and IRF4 expression in peripheral mononuclear cells are potential prognostic factors for advanced lung cancer. (2017 Feb)Wu YYJ Formos Med Assoc