Gene info: ID 9429

Gene: ABCG2

GENE ID: 9429

Synonyms: ABC15|ABCP|BCRP|BCRP1|BMDP|CD338|CDw338|EST157481|GOUT1|MRX|MXR|MXR-1|MXR1|UAQTL1

Description: ATP binding cassette subfamily G member 2 (Junior blood group)

Gene type: protein-coding

Location: 4q22.1

dbXrefs: Ensembl:ENSG00000118777 MIM:603756 Vega:OTTHUMG00000130601 UniprotKB:Q9UNQ0

RefSeq: NG_032067.2

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: OD|ND|AD

# Publications: 17

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 3.219e-1 (AD) 8.531e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
A2M	0.853
ABCB1	0.851
PTPRB	0.85
COBLL1	0.82
EMCN	0.812
CD34	0.809
CLEC14A	0.807
USHBP1	0.8
LEF1	0.793
CYYR1	0.789

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
TEPP	-0.325
FAM43B	-0.312
BCL2L10	-0.303
CHST8	-0.291
GNB1L	-0.289
MESP1	-0.285
TNFSF9	-0.284
CILP2	-0.276
KISS1R	-0.276
GGN	-0.269

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00091	Cyclosporine	Small Molecule	59865-13-3	Approved\|Investigational	Transporter
DB00158	Folic Acid	Small Molecule	59-30-3	Approved\|Nutraceutical	Transporter
DB00175	Pravastatin	Small Molecule	81093-37-0	Approved	Transporter
DB00213	Pantoprazole	Small Molecule	102625-70-7	Approved	Transporter
DB00220	Nelfinavir	Small Molecule	159989-64-7	Approved	Transporter
DB00242	Cladribine	Small Molecule	4291-63-8	Approved\|Investigational	Transporter
DB00255	Diethylstilbestrol	Small Molecule	56-53-1	Approved\|Investigational	Transporter
DB00285	Venlafaxine	Small Molecule	93413-69-5	Approved	Transporter
DB00286	Conjugated estrogens	Small Molecule	12126-59-9	Approved	Transporter
DB00317	Gefitinib	Small Molecule	184475-35-2	Approved\|Investigational	Transporter
DB00338	Omeprazole	Small Molecule	73590-58-6	Approved\|Investigational	Transporter
DB00398	Sorafenib	Small Molecule	284461-73-0	Approved\|Investigational	Transporter
DB00439	Cerivastatin	Small Molecule	145599-86-6	Approved\|Withdrawn	Transporter
DB00444	Teniposide	Small Molecule	29767-20-2	Approved	Transporter
DB00448	Lansoprazole	Small Molecule	103577-45-3	Approved\|Investigational	Transporter
DB00457	Prazosin	Small Molecule	19216-56-9	Approved	Transporter
DB00470	Dronabinol	Small Molecule	1972-08-3	Approved\|Illicit	Transporter
DB00495	Zidovudine	Small Molecule	30516-87-1	Approved	Transporter
DB00503	Ritonavir	Small Molecule	155213-67-5	Approved\|Investigational	Transporter
DB00515	Cisplatin	Small Molecule	15663-27-1	Approved	Transporter
DB00526	Oxaliplatin	Small Molecule	61825-94-3	Approved\|Investigational	Transporter
DB00530	Erlotinib	Small Molecule	183321-74-6	Approved\|Investigational	Transporter
DB00541	Vincristine	Small Molecule	57-22-7	Approved\|Investigational	Transporter
DB00544	Fluorouracil	Small Molecule	51-21-8	Approved	Transporter
DB00549	Zafirlukast	Small Molecule	107753-78-6	Approved\|Investigational	Transporter
DB00563	Methotrexate	Small Molecule	59-05-2	Approved	Transporter
DB00602	Ivermectin	Small Molecule	70288-86-7	Approved\|Investigational	Transporter
DB00619	Imatinib	Small Molecule	152459-95-5	Approved	Transporter
DB00624	Testosterone	Small Molecule	58-22-0	Approved\|Investigational	Transporter
DB00631	Clofarabine	Small Molecule	123318-82-1	Approved\|Investigational	Transporter
DB00655	Estrone	Small Molecule	53-16-7	Approved	Transporter
DB00661	Verapamil	Small Molecule	52-53-9	Approved	Transporter
DB00669	Sumatriptan	Small Molecule	103628-46-2	Approved\|Investigational	Transporter
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Transporter
DB00688	Mycophenolate mofetil	Small Molecule	128794-94-5	Approved\|Investigational	Transporter
DB00694	Daunorubicin	Small Molecule	20830-81-3	Approved	Transporter
DB00698	Nitrofurantoin	Small Molecule	67-20-9	Approved	Transporter
DB00709	Lamivudine	Small Molecule	134678-17-4	Approved\|Investigational	Transporter
DB00740	Riluzole	Small Molecule	1744-22-5	Approved\|Investigational	Transporter
DB00741	Hydrocortisone	Small Molecule	50-23-7	Approved	Transporter
DB00762	Irinotecan	Small Molecule	97682-44-5	Approved\|Investigational	Transporter
DB00773	Etoposide	Small Molecule	33419-42-0	Approved	Transporter
DB00783	Estradiol	Small Molecule	50-28-2	Approved\|Investigational	Transporter
DB00795	Sulfasalazine	Small Molecule	599-79-1	Approved	Transporter
DB00921	Buprenorphine	Small Molecule	52485-79-7	Approved\|Illicit\|Investigational	Transporter
DB00958	Carboplatin	Small Molecule	41575-94-4	Approved	Transporter
DB00966	Telmisartan	Small Molecule	144701-48-4	Approved\|Investigational	Transporter
DB00970	Dactinomycin	Small Molecule	50-76-0	Approved\|Investigational	Transporter
DB00973	Ezetimibe	Small Molecule	163222-33-1	Approved	Transporter
DB00997	Doxorubicin	Small Molecule	23214-92-8	Approved\|Investigational	Transporter
DB01016	Glyburide	Small Molecule	10238-21-8	Approved	Transporter
DB01030	Topotecan	Small Molecule	123948-87-8	Approved\|Investigational	Transporter
DB01051	Novobiocin	Small Molecule	303-81-1	Approved\|Investigational	Transporter
DB01094	Hesperetin	Small Molecule	520-33-2	Approved	Transporter
DB01097	Leflunomide	Small Molecule	75706-12-6	Approved\|Investigational	Transporter
DB01098	Rosuvastatin	Small Molecule	287714-41-4	Approved	Transporter
DB01129	Rabeprazole	Small Molecule	117976-89-3	Approved\|Investigational	Transporter
DB01204	Mitoxantrone	Small Molecule	65271-80-9	Approved\|Investigational	Transporter
DB01229	Paclitaxel	Small Molecule	33069-62-4	Approved	Transporter
DB01232	Saquinavir	Small Molecule	127779-20-8	Approved\|Investigational	Transporter
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Transporter
DB01248	Docetaxel	Small Molecule	114977-28-5	Approved\|Investigational	Transporter
DB01254	Dasatinib	Small Molecule	302962-49-8	Approved\|Investigational	Transporter
DB01268	Sunitinib	Small Molecule	557795-19-4	Approved\|Investigational	Transporter
DB01645	Genistein	Small Molecule	446-72-0	Investigational	Transporter
DB01685	Topiroxostat	Small Molecule	577778-58-6	Approved\|Investigational	Transporter
DB02115	Daidzin	Small Molecule	552-66-9	Experimental	Transporter
DB03467	Naringenin	Small Molecule	480-41-1	Experimental	Transporter
DB03496	Alvocidib	Small Molecule	146426-40-6	Experimental\|Investigational	Transporter
DB04216	Quercetin	Small Molecule	117-39-5	Experimental\|Investigational	Transporter
DB04348	Taurocholic Acid	Small Molecule	81-24-3	Experimental	Transporter
DB04540	Cholesterol	Small Molecule	57-88-5	Approved\|Experimental\|Investigational	Transporter
DB04690	Camptothecin	Small Molecule	7689-03-4	Experimental	Transporter
DB04868	Nilotinib	Small Molecule	641571-10-0	Approved\|Investigational	Transporter
DB04881	Elacridar	Small Molecule	143664-11-3	Investigational	Transporter
DB05239	Cobimetinib	Small Molecule	934660-93-2	Approved\|Investigational	Transporter
DB05294	Vandetanib	Small Molecule	443913-73-3	Approved	Transporter
DB06290	Simeprevir	Small Molecule	923604-59-5	Approved	Transporter
DB06589	Pazopanib	Small Molecule	444731-52-6	Approved	Transporter
DB06605	Apixaban	Small Molecule	503612-47-3	Approved	Transporter
DB06654	Safinamide	Small Molecule	133865-89-1	Approved\|Investigational	Transporter
DB06772	Cabazitaxel	Small Molecule	183133-96-2	Approved	Transporter
DB08828	Vismodegib	Small Molecule	879085-55-9	Approved\|Investigational	Transporter
DB08860	Pitavastatin	Small Molecule	147511-69-1	Approved	Transporter
DB08864	Rilpivirine	Small Molecule	500287-72-9	Approved	Transporter
DB08880	Teriflunomide	Small Molecule	163451-81-8	Approved	Transporter
DB08881	Vemurafenib	Small Molecule	918504-65-1	Approved	Transporter
DB08896	Regorafenib	Small Molecule	755037-03-7	Approved	Transporter
DB08901	Ponatinib	Small Molecule	943319-70-8	Approved\|Investigational	Transporter
DB08912	Dabrafenib	Small Molecule	-	Approved\|Investigational	Transporter
DB08916	Afatinib	Small Molecule	850140-72-6	Approved	Transporter
DB08930	Dolutegravir	Small Molecule	1051375-16-6	Approved	Transporter
DB08931	Riociguat	Small Molecule	625115-55-1	Approved	Transporter
DB08934	Sofosbuvir	Small Molecule	1190307-88-0	Approved	Transporter
DB09027	Ledipasvir	Small Molecule	1256388-51-8	Approved	Transporter
DB09054	Idelalisib	Small Molecule	870281-82-6	Approved	Transporter
DB09061	Cannabidiol	Small Molecule	13956-29-1	Approved\|Investigational	Transporter
DB09065	Cobicistat	Small Molecule	1004316-88-4	Approved	Transporter
DB09078	Lenvatinib	Small Molecule	417716-92-8	Approved\|Investigational	Transporter
DB09102	Daclatasvir	Small Molecule	1009119-64-5	Approved\|Investigational	Transporter
DB09183	Dasabuvir	Small Molecule	1132935-63-7	Approved	Transporter
DB09291	Rolapitant	Small Molecule	552292-08-7	Approved\|Investigational	Transporter
DB09296	Ombitasvir	Small Molecule	1258226-87-7	Approved\|Investigational	Transporter
DB09330	Osimertinib	Small Molecule	1421373-65-0	Approved	Transporter
DB11363	Alectinib	Small Molecule	-	Approved\|Investigational	Transporter
DB11581	Venetoclax	Small Molecule	1257044-40-8	Approved\|Investigational	Transporter
DB11613	Velpatasvir	Small Molecule	1377049-84-7	Approved\|Investigational	Transporter
DB11633	Isavuconazole	Small Molecule	241479-67-4	Approved\|Investigational	Transporter
DB11817	Baricitinib	Small Molecule	1187594-09-7	Approved\|Investigational	Transporter
DB11827	Ertugliflozin	Small Molecule	1210344-57-2	Approved\|Investigational	Transporter
DB11901	Apalutamide	Small Molecule	956104-40-8	Approved\|Investigational	Transporter
DB11943	Delafloxacin	Small Molecule	189279-58-1	Approved\|Investigational	Transporter
DB12001	Abemaciclib	Small Molecule	1231929-97-7	Approved\|Investigational	Transporter
DB12026	Voxilaprevir	Small Molecule	1535212-07-7	Approved\|Investigational	Transporter
DB12070	Letermovir	Small Molecule	917389-32-3	Approved\|Investigational	Transporter
DB12267	Brigatinib	Small Molecule	1197953-54-0	Approved\|Investigational	Transporter
DB12332	Rucaparib	Small Molecule	283173-50-2	Approved\|Investigational	Transporter
DB12483	Copanlisib	Small Molecule	1032568-63-0	Approved\|Investigational	Transporter
DB13874	Enasidenib	Small Molecule	1446502-11-9	Approved\|Investigational	Transporter
DB13878	Pibrentasvir	Small Molecule	1353900-92-1	Approved\|Investigational	Transporter
DB13879	Glecaprevir	Small Molecule	1365970-03-1	Approved\|Investigational	Transporter
DB13943	Testosterone cypionate	Small Molecule	58-20-8	Approved	Transporter
DB13944	Testosterone enanthate	Small Molecule	315-37-7	Approved	Transporter
DB13946	Testosterone undecanoate	Small Molecule	5949-44-0	Approved\|Investigational	Transporter
DB13952	Estradiol acetate	Small Molecule	4245-41-4	Approved\|Investigational	Transporter
DB13953	Estradiol benzoate	Small Molecule	50-50-0	Approved\|Investigational	Transporter
DB13954	Estradiol cypionate	Small Molecule	313-06-4	Approved\|Investigational	Transporter
DB13955	Estradiol dienanthate	Small Molecule	7732-97-0	Approved\|Investigational	Transporter
DB13956	Estradiol valerate	Small Molecule	979-32-8	Approved\|Investigational	Transporter
DB04851	Biricodar dicitrate	Small Molecule	174254-13-8	Investigational	Target

ID	Drug Name	Action	PubMed
C569670	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	"ABCG2 protein results in increased transport of 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one"	22696419
C569670	1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one	"ABCG2 protein results in increased transport of 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one"	22696419
C033146	1-hydroxypyrene	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite]"	24140465
C033146	1-hydroxypyrene	ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite	24140465
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"ABCG2 protein affects the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased phosphorylation of AKT1 protein]"	20522663
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"ABCG2 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"	20522663
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]"	20522663
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCG2 mRNA"	25542188
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased activity of ABCG2 protein"	28031414
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA]"	15917307
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 protein]"	15917307
C016403	2,4-dinitrotoluene	"2,4-dinitrotoluene affects the expression of ABCG2 mRNA"	21346803
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in increased expression of ABCG2 mRNA]	21712253
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in increased expression of ABCG2 protein]	21712253
C107497	2',5'-dihydroxychalcone	"2',5'-dihydroxychalcone promotes the reaction [ABCG2 protein results in increased export of Glutathione]"	20332504
C107497	2',5'-dihydroxychalcone	"ABCG2 protein results in increased susceptibility to 2',5'-dihydroxychalcone"	20332504
C023514	2,6-dinitrotoluene	"2,6-dinitrotoluene affects the expression of ABCG2 mRNA"	21346803
C077584	2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine	"ABCG2 protein affects the transport of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"	18322075
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Equol inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"tryptoquivaline inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Equol inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"tryptoquivaline inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ABCG2 protein"	18680760
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ABCG2 mRNA"	18680760
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	18680760
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 gene polymorphism results in decreased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	18710444
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in decreased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	18680760
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in increased secretion of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	23081912
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	22892056
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Beclomethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Cadmium Chloride inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	22892056
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Dexamethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Estradiol inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Methylprednisolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"Triamcinolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	14559835
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein affects the abundance of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	21544799
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	15722455\|1832207
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in increased secretion of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	23081912
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	14559835
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein results in decreased uptake of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	15917307
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	"ABCG2 protein affects the transport of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"	18322075
C060533	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"ABCG2 protein affects the transport of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	18322075
C521104	2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide	ABCG2 protein affects the transport of 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide	19223659
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased expression of ABCG2 mRNA]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	24389113
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	23625689
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased expression of ABCG2 mRNA	23625689
C018855	2-tert-butylhydroquinone	2-tert-butylhydroquinone results in increased expression of ABCG2 mRNA	17077187
C018855	2-tert-butylhydroquinone	2-tert-butylhydroquinone results in increased expression of ABCG2 protein	17077187
C018855	2-tert-butylhydroquinone	AHR protein promotes the reaction [2-tert-butylhydroquinone results in increased expression of ABCG2 protein]	17077187
C524256	3-(4-chloro-3-nitrolphenyl)-1,2,3-oxadiazolium-5-olate	"3-(4-chloro-3-nitrolphenyl)-1,2,3-oxadiazolium-5-olate inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	27417255
C434003	3-(4-methylphenylsulfonyl)-2-propenenitrile	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in increased expression of ABCG2 mRNA]	21712253
C434003	3-(4-methylphenylsulfonyl)-2-propenenitrile	3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in increased expression of ABCG2 protein]	21712253
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of danofloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of difloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of enrofloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of Mitoxantrone]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of Nitrofurantoin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of danofloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of difloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of enrofloxacin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Nitrofurantoin]"	21821808
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine"	23200901
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of mesaconitine"	23200901
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein"	24389113
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Glyburide]"	26850786
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	16442095
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased secretion of 1-hydroxypyrene metabolite]"	24140465
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]"	18834354
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide]"	26850786
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein"	18623116\|1868076
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] inhibits the reaction [Folic Acid deficiency results in decreased susceptibility to Mitoxantrone]"	18623116
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of Benzo(a)pyrene metabolite"	15917307
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of benzoylhypaconine"	23200901
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine"	23200901
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of mesaconitine"	23200901
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	18680760
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in increased expression of ABCG2 protein"	27879033
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]"	17437964
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of abacavir]"	19056916
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]"	19056916
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Prazosin]"	19056916
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]"	19056916
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased secretion of diferuloylputrescine metabolite"	20089784
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	27417255
C541506	3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein"	15917307\|2008978
C542465	3-keto-N-aminoethylaminoethylcaproyldihydrocinnamoyl cyclopamine	3-keto-N-aminoethylaminoethylcaproyldihydrocinnamoyl cyclopamine results in decreased expression of ABCG2 mRNA	21625222
C542465	3-keto-N-aminoethylaminoethylcaproyldihydrocinnamoyl cyclopamine	3-keto-N-aminoethylaminoethylcaproyldihydrocinnamoyl cyclopamine results in decreased expression of ABCG2 protein	21625222
C583126	4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid	"4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]"	27423937
C583126	4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid	"4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid results in decreased expression of ABCG2 protein"	27423937
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C064297	4-hydroxystilbene	4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C000603500	4'-methoxy-1-naphthylfenoterol	4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]	27423937
C000603500	4'-methoxy-1-naphthylfenoterol	4'-methoxy-1-naphthylfenoterol results in decreased expression of ABCG2 protein	27423937
C498826	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	ABCG2 protein affects the susceptibility to 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	24954033
C041594	4-nonylphenol	4-nonylphenol results in decreased expression of ABCG2 protein	27036933
C041594	4-nonylphenol	fulvestrant affects the reaction [4-nonylphenol results in decreased expression of ABCG2 protein]	27036933
C022909	5-methoxypsoralen	5-methoxypsoralen results in decreased activity of ABCG2 protein	29079042
C022909	5-methoxypsoralen	[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone	29079042
C022909	5-methoxypsoralen	5-methoxypsoralen results in increased expression of ABCG2 mRNA	29079042
C022909	5-methoxypsoralen	Novobiocin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCG2 protein]	29079042
C022909	5-methoxypsoralen	Novobiocin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
C546607	6,2',4'-trimethoxyflavone	"6,2',4'-trimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of ABCG2 protein]"	22912337
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C475093	6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime	"[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with NR1I3 protein] results in increased expression of ABCG2 mRNA"	22093699
C475093	6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime	"6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]"	22093699
C475093	6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime	"[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime promotes the reaction [[NR1I3 protein binds to RXRA protein] which binds to ABCG2 promoter]] which results in increased expression of ABCG2 mRNA"	22093699\|2209369
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of ABCG2 mRNA	18624906
C483321	6-bromoindirubin-3'-oxime	6-bromoindirubin-3'-oxime results in increased expression of ABCG2 protein	18624906
C580599	6-OH-BDE-47	6-OH-BDE-47 inhibits the reaction [ABCG2 protein results in increased export of Prazosin]	28031414
C580599	6-OH-BDE-47	6-OH-BDE-47 results in decreased activity of ABCG2 protein	28031414
C502336	6-prenylchrysin	6-prenylchrysin results in decreased activity of ABCG2 protein	15930306
C011864	7-hydroxymethotrexate	ABCG2 protein affects the transport of 7-hydroxymethotrexate	17032904
C011864	7-hydroxymethotrexate	ABCG2 protein results in increased export of 7-hydroxymethotrexate	17032904
C011864	7-hydroxymethotrexate	pantoprazole inhibits the reaction [ABCG2 protein affects the transport of 7-hydroxymethotrexate]	17032904
C011864	7-hydroxymethotrexate	Protons promotes the reaction [ABCG2 protein results in increased export of 7-hydroxymethotrexate]	17032904
C015929	8-((4-chlorophenyl)thio)cyclic-3',5'-AMP	"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCG2 mRNA"	27160211
C063380	9-((2-phosphonylmethoxy)ethyl)guanine	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C106538	abacavir	[Estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir	25844889
C106538	abacavir	"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir"	25844889
C106538	abacavir	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of abacavir]"	19056916
C106538	abacavir	ABCG2 protein results in decreased export of abacavir	17437964
C106538	abacavir	ABCG2 protein results in increased export of abacavir	19056916
C106538	abacavir	Elacridar inhibits the reaction [ABCG2 protein results in decreased export of abacavir]	17437964
C106538	abacavir	Elacridar inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
C106538	abacavir	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
C106538	abacavir	pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
D000082	Acetaminophen	Acetaminophen results in decreased expression of ABCG2 mRNA	21420995\|2463134
D000082	Acetaminophen	Acetaminophen results in decreased expression of and results in decreased activity of ABCG2 protein	24631341
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCG2 protein	17627974
D000082	Acetaminophen	Acetaminophen affects the expression of ABCG2 mRNA	17562736
D000082	Acetaminophen	[Clofibrate co-treated with Acetaminophen] affects the expression of ABCG2 mRNA	17585979
D000082	Acetaminophen	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ABCG2 mRNA]	17585979
D000082	Acetaminophen	ABCG2 protein affects the export of Acetaminophen analog	15860656
D000082	Acetaminophen	Acetaminophen results in decreased expression of ABCG2 protein	24631341
D000082	Acetaminophen	Acetaminophen results in increased expression of ABCG2 mRNA	24631341
D000212	Acyclovir	ABCG2 protein affects the transport of Acyclovir	21859328
D000212	Acyclovir	tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of Acyclovir]	21859328
D000212	Acyclovir	ABCG2 protein affects the transport of Acyclovir	21859328
D000255	Adenosine Triphosphate	ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate	18829547
D000255	Adenosine Triphosphate	lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of ABCG2 protein	20106945
D016604	Aflatoxin B1	[Aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCG2 protein	23402939
D016604	Aflatoxin B1	[Aflatoxin B1 co-treated with finrozole] results in increased expression of ABCG2 mRNA	23402939
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of ABCG2 protein	23402939
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of ABCG2 mRNA	23402939
D000393	Air Pollutants	Air Pollutants analog results in decreased expression of ABCG2 mRNA	21757418
C027186	albendazole sulfoxide	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C027186	albendazole sulfoxide	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C027186	albendazole sulfoxide	ABCG2 protein affects the transport of albendazole sulfoxide	15703302
C027186	albendazole sulfoxide	ABCG2 protein affects the transport of albendazole sulfoxide	15703302
C027186	albendazole sulfoxide	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
D000493	Allopurinol	Allopurinol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in decreased activity of ABCG2 protein	18257033
C103505	AM 251	"4-(4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-5-yl)benzoic acid inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]"	27423937
C103505	AM 251	4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of ABCG2 protein]	27423937
C103505	AM 251	AM 251 results in increased expression of ABCG2 protein	27423937
C068073	Am 580	Am 580 promotes the reaction [Tretinoin results in increased expression of ABCG2 mRNA]	20562004
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of ABCG2 mRNA	16483693
D000735	Androstenedione	Androstenedione inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
D000735	Androstenedione	Androstenedione results in decreased activity of ABCG2 protein	22581381
D000927	Anticonvulsants	ABCG2 protein results in decreased susceptibility to Anticonvulsants	15581025
C006632	arsenic trioxide	arsenic trioxide affects the expression of ABCG2 mRNA	22214486
C006632	arsenic trioxide	arsenic trioxide results in increased expression of ABCG2 mRNA	17547211\|2252195
D000069059	Atorvastatin Calcium	Atorvastatin Calcium results in increased expression of ABCG2 mRNA	25278499
C406592	azaspiracid	azaspiracid results in increased expression of ABCG2 mRNA	28939011
D001379	Azathioprine	Azathioprine results in decreased expression of ABCG2 mRNA	27765674
C041552	azidoprazosin	azidoprazosin binds to ABCG2 protein	18829547
C041552	azidoprazosin	lapatinib inhibits the reaction [azidoprazosin binds to ABCG2 protein]	18829547
C087670	azoxystrobin	azoxystrobin inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D001507	Beclomethasone	"Beclomethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
D001507	Beclomethasone	Beclomethasone inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
D001507	Beclomethasone	Beclomethasone results in increased activity of ABCG2 protein	16442095
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in decreased expression of ABCG2 mRNA	26377693
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of ABCG2 mRNA	19737606
C022921	benzo(k)fluoranthene	AHR protein promotes the reaction [benzo(k)fluoranthene results in increased expression of ABCG2 protein]	17077187
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]	15917307
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of ABCG2 mRNA	15917307
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of ABCG2 protein	17077187
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of and results in increased activity of ABCG2 protein	15917307
D001564	Benzo(a)pyrene	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of Benzo(a)pyrene metabolite"	15917307
D001564	Benzo(a)pyrene	"6,2',4'-trimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of ABCG2 protein]"	22912337
D001564	Benzo(a)pyrene	ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite	15917307
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased activity of ABCG2 protein	27475308
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCG2 mRNA	15917307\|2010694
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCG2 protein	15917307\|2291233
D001564	Benzo(a)pyrene	benzo(k)fluoranthene promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]	15917307
D001564	Benzo(a)pyrene	"indolo(3,2-b)carbazole promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]"	15917307
D001564	Benzo(a)pyrene	N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Benzo(a)pyrene results in increased expression of ABCG2 protein]	22912337
D001564	Benzo(a)pyrene	oltipraz promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]	15917307
D001564	Benzo(a)pyrene	ABCG2 protein results in increased transport of Benzo(a)pyrene	25451572
D001564	Benzo(a)pyrene	ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite	25451572
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of ABCG2 mRNA	28651000
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ABCG2 mRNA	22227637
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ABCG2 mRNA"	20382639
C479202	benzoylhypaconine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of benzoylhypaconine"	23200901
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	"benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA]"	17077187
D004958	Estradiol	ESR1 protein promotes the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D004958	Estradiol	Estradiol affects the expression of ABCG2 protein	17823853
D004958	Estradiol	[Estradiol binds to ESR1 protein] which results in decreased expression of ABCG2	15695404
D004958	Estradiol	[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA	17823853
D004958	Estradiol	[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein	17823853
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCG2 mRNA	19619570
D004958	Estradiol	"Estradiol inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
D004958	Estradiol	Estradiol inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
D004958	Estradiol	Estradiol results in decreased activity of ABCG2 protein	22581381\|2584488
D004958	Estradiol	[Estradiol results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir	25844889
D004958	Estradiol	Estradiol results in decreased expression of ABCG2	15695404
D004958	Estradiol	Estradiol results in decreased expression of ABCG2 protein	27036933
D004958	Estradiol	Estradiol results in increased expression of ABCG2 mRNA	16849015\|1958084
D004958	Estradiol	Estradiol results in increased expression of ABCG2 protein	16849015
D004958	Estradiol	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D004958	Estradiol	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
D004958	Estradiol	fulvestrant affects the reaction [Estradiol results in decreased expression of ABCG2 protein]	27036933
D004958	Estradiol	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D004958	Estradiol	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
D004958	Estradiol	Progesterone inhibits the reaction [Estradiol results in increased expression of ABCG2]	16849015
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCG2]	15695404
D004958	Estradiol	Estradiol results in decreased expression of ABCG2 protein	21360409
C002887	bis(4-nitrophenyl)phosphate	bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]	24727322
C002887	bis(4-nitrophenyl)phosphate	bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the stability of Everolimus]	24727322
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	24389113
C017807	bisbenzimide ethoxide trihydrochloride	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	monepantel inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]"	24389113
C017807	bisbenzimide ethoxide trihydrochloride	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
C017807	bisbenzimide ethoxide trihydrochloride	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	24389113
C017807	bisbenzimide ethoxide trihydrochloride	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	monepantel inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	salicylamide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C017807	bisbenzimide ethoxide trihydrochloride	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride	26850786
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in decreased abundance of bisbenzimide ethoxide trihydrochloride	12869632
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride	26850786\|2690737
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	12869632
C017807	bisbenzimide ethoxide trihydrochloride	bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCG2 protein	27475308
C017807	bisbenzimide ethoxide trihydrochloride	Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
C017807	bisbenzimide ethoxide trihydrochloride	danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26850786
C017807	bisbenzimide ethoxide trihydrochloride	Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]	26850786
C017807	bisbenzimide ethoxide trihydrochloride	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	[MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride	19239227
C017807	bisbenzimide ethoxide trihydrochloride	Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
C017807	bisbenzimide ethoxide trihydrochloride	Tobacco Smoke Pollution inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	27450509
C017807	bisbenzimide ethoxide trihydrochloride	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	27450509
C017807	bisbenzimide ethoxide trihydrochloride	verlukast inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
C017807	bisbenzimide ethoxide trihydrochloride	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C017807	bisbenzimide ethoxide trihydrochloride	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]"	26907376
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride	26907376
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride	27288731
C017807	bisbenzimide ethoxide trihydrochloride	azoxystrobin inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	carbendazim inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Chlormequat inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Chlorpyrifos inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	diflufenican inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Dimethoate inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	dimethomorph inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	dithianone inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	ioxynil inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Methiocarb inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C017807	bisbenzimide ethoxide trihydrochloride	propamocarb inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	rimsulfuron inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	tolclofos-methyl inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	tryptoquivaline inhibits the reaction [Chlorpyrifos inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]]	27288731
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	24389113
C017807	bisbenzimide ethoxide trihydrochloride	albendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C017807	bisbenzimide ethoxide trihydrochloride	9-((2-phosphonylmethoxy)ethyl)guanine analog inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C017807	bisbenzimide ethoxide trihydrochloride	ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride	23856525
C017807	bisbenzimide ethoxide trihydrochloride	zosuquidar trihydrochloride inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C006780	bisphenol A	ABCG2 protein results in increased transport of bisphenol A	24014645
C006780	bisphenol A	bisphenol A results in decreased activity of ABCG2 protein	24014645
C006780	bisphenol A	bisphenol A results in decreased expression of ABCG2 mRNA	27036933
C006780	bisphenol A	bisphenol A results in decreased expression of ABCG2 protein	27036933
C006780	bisphenol A	fulvestrant affects the reaction [bisphenol A results in decreased expression of ABCG2 protein]	27036933
C006780	bisphenol A	bisphenol A results in decreased expression of ABCG2 mRNA	25181051
C006780	bisphenol A	bisphenol A results in decreased expression of and results in decreased activity of ABCG2 protein	24945792
D002065	Buspirone	Buspirone results in decreased expression of ABCG2 mRNA	24136188
D002104	Cadmium	Cadmium results in increased expression of ABCG2 mRNA	17547211
D019256	Cadmium Chloride	"Cadmium Chloride inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	22892056
D019256	Cadmium Chloride	Cadmium Chloride inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	22892056
D019256	Cadmium Chloride	Cadmium Chloride results in decreased activity of ABCG2 protein	22892056
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCG2 mRNA	17547211
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ABCG2 mRNA	23741332
D002220	Carbamazepine	Carbamazepine results in increased expression of ABCG2 mRNA	17112801
C006698	carbendazim	carbendazim inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C010063	carbonyl sulfide	carbonyl sulfide results in decreased expression of ABCG2 mRNA	19395590
D002392	Catechin	Catechin results in decreased expression of ABCG2 protein	17077187
C104000	CD 2608	CD 2608 promotes the reaction [Tretinoin results in increased expression of ABCG2 mRNA]	20562004
D000068579	Celecoxib	Celecoxib results in decreased expression of ABCG2 mRNA	18202791
C086276	cerivastatin	ABCG2 protein affects the export of cerivastatin	15901800
D002706	Chlordan	Chlordan results in decreased activity of ABCG2 protein	24464585
D002706	Chlordan	Chlordan results in increased expression of ABCG2 mRNA	24464585
D007631	Chlordecone	Chlordecone results in decreased activity of ABCG2 protein	24464585
D002716	Chlormequat	Chlormequat inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D020245	p-Chloromercuribenzoic Acid	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
D020245	p-Chloromercuribenzoic Acid	p-Chloromercuribenzoic Acid results in increased expression of ABCG2 mRNA	26272509
D002737	Chloroprene	Chloroprene results in increased expression of ABCG2 mRNA	23125180
D002738	Chloroquine	Chloroquine results in decreased expression of ABCG2 mRNA	27692344
D002738	Chloroquine	Chloroquine results in decreased expression of ABCG2 protein	27692344
D002746	Chlorpromazine	Chlorpromazine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCG2 mRNA	22285354\|2854982
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ABCG2 protein	28549829
D004390	Chlorpyrifos	Chlorpyrifos inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D004390	Chlorpyrifos	tryptoquivaline inhibits the reaction [Chlorpyrifos inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]]	27288731
D002784	Cholesterol	Cholesterol results in increased activity of ABCG2 protein	27475308
D002784	Cholesterol	Sulfasalazine promotes the reaction [Cholesterol results in increased activity of ABCG2 protein]	27475308
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABCG2 gene	20938992
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCG2 mRNA	17640958\|2438491
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCG2 protein	17640958
D002857	Chromium	Chromium results in increased expression of ABCG2 mRNA	17547211
C074702	chromium hexavalent ion	chromium hexavalent ion affects the expression of ABCG2 mRNA	28472532
C043561	chrysin	chrysin inhibits the reaction [ABCG2 protein results in increased secretion of Mitoxantrone]	17093006
C043561	chrysin	chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	17093006
C043561	chrysin	chrysin results in decreased activity of ABCG2 protein	20457140
C043561	chrysin	[chrysin results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan	20457140
C043561	chrysin	chrysin results in decreased expression of ABCG2 mRNA	20816778
C043561	chrysin	chrysin results in increased expression of ABCG2 mRNA	17077187
C043561	chrysin	chrysin results in increased expression of ABCG2 protein	20457140
C043561	chrysin	chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	17093006
C043561	chrysin	chrysin inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]	19732493
C043561	chrysin	chrysin results in decreased activity of ABCG2 protein	17093006
D002927	Cimetidine	ABCG2 protein affects the transport of Cimetidine	15365089
D002927	Cimetidine	Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D002927	Cimetidine	ABCG2 protein affects the transport of Cimetidine	15365089\|1572245
D002927	Cimetidine	Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D002939	Ciprofloxacin	Ciprofloxacin results in increased expression of ABCG2 protein	26947806
D002994	Clofibrate	[Clofibrate co-treated with Acetaminophen] affects the expression of ABCG2 mRNA	17585979
D002994	Clofibrate	Clofibrate results in increased expression of ABCG2 mRNA	16467456\|1758597
D002994	Clofibrate	Clofibrate results in increased expression of ABCG2 protein	16467456
D002994	Clofibrate	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ABCG2 mRNA]	17585979
D002994	Clofibrate	PPARA promotes the reaction [Clofibrate results in increased expression of ABCG2 mRNA]	16467456
D002994	Clofibrate	PPARA promotes the reaction [Clofibrate results in increased expression of ABCG2 protein]	16467456
D003024	Clozapine	Clozapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of ABCG2 mRNA	19376846
D005576	Colforsin	Colforsin results in increased expression of ABCG2 mRNA	19580841
D003345	Corticosterone	Corticosterone results in decreased activity of ABCG2 protein	15365089
C551994	crizotinib	crizotinib results in decreased activity of ABCG2 protein	28369651
D003474	Curcumin	AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein]	17077187
D003474	Curcumin	Curcumin results in increased expression of ABCG2 protein	17077187
D003520	Cyclophosphamide	ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D016572	Cyclosporine	Cyclosporine affects the expression of ABCG2 mRNA	24973091
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16636798
D016572	Cyclosporine	Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
D016572	Cyclosporine	Cyclosporine results in decreased activity of ABCG2 protein	18581209
D016572	Cyclosporine	Cyclosporine results in increased expression of ABCG2 mRNA	27989131
D016572	Cyclosporine	Cyclosporine results in decreased expression of ABCG2 mRNA	19770486
D003524	Cyclosporins	Cyclosporins affects the activity of ABCG2 protein	15788683
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Daunorubicin results in increased expression of ABCG2 mRNA]	20019844
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Doxorubicin results in increased expression of ABCG2 mRNA]	20019844
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Mitoxantrone results in increased expression of ABCG2 mRNA]	20019844
D003609	Dactinomycin	Dactinomycin inhibits the reaction [SHH protein alternative form results in increased expression of ABCG2 protein]	21625222
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Sulfasalazine results in increased expression of ABCG2 mRNA]	20019844
C004742	daidzein	ABCG2 protein affects the transport of daidzein	18322075
C004742	daidzein	[Genistein co-treated with daidzein] inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	19754918
C068581	danofloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of danofloxacin]"	21821808
C068581	danofloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of danofloxacin]"	21821808
C068581	danofloxacin	ABCG2 protein polymorphism results in increased export of danofloxacin	21821808
C068581	danofloxacin	ABCG2 protein results in increased export of danofloxacin	21821808
C068581	danofloxacin	danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
C068581	danofloxacin	danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D003620	Dantrolene	ABCG2 protein affects the transport of Dantrolene	18322075
C523797	danusertib	ABCG2 protein results in decreased susceptibility to danusertib	21541334
D003630	Daunorubicin	Dactinomycin inhibits the reaction [Daunorubicin results in increased expression of ABCG2 mRNA]	20019844
D003630	Daunorubicin	Daunorubicin results in increased expression of ABCG2 mRNA	20019844
D003634	DDT	DDT metabolite results in decreased activity of ABCG2 protein	23169446
C014347	decitabine	decitabine affects the expression of ABCG2 mRNA	16954373
C014347	decitabine	decitabine affects the expression of ABCG2 protein	16954373
C014347	decitabine	decitabine inhibits the reaction [HDAC1 protein binds to ABCG2 promoter]	16954373
C014347	decitabine	decitabine inhibits the reaction [SIN3A protein binds to ABCG2 promoter]	16954373
C014347	decitabine	decitabine inhibits the reaction [Smoke results in decreased expression of ABCG2 mRNA]	21095227
C014347	decitabine	VHL protein promotes the reaction [decitabine results in increased expression of ABCG2 mRNA]	16954373
C014347	decitabine	VHL protein promotes the reaction [decitabine results in increased expression of ABCG2 protein]	16954373
D047630	Depsipeptides	Depsipeptides affects the expression of ABCG2 mRNA	16954373
D047630	Depsipeptides	Depsipeptides affects the expression of ABCG2 protein	16954373
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
C494355	desisobutyrylciclesonide	desisobutyrylciclesonide results in increased activity of ABCG2 protein	16442095
D003907	Dexamethasone	"Dexamethasone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
D003907	Dexamethasone	Dexamethasone results in decreased expression of ABCG2 mRNA	20607812
D016190	Carboplatin	Carboplatin results in decreased expression of ABCG2 mRNA	27692344
D016190	Carboplatin	Carboplatin results in decreased expression of ABCG2 protein	27692344
C061481	dibenzoylmethane	dibenzoylmethane results in increased expression of ABCG2 protein	17077187
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of ABCG2 mRNA	17361019\|2126653
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of ABCG2 mRNA	28962523
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in increased expression of ABCG2 mRNA	27392435
D002945	Cisplatin	[Cisplatin co-treated with Paclitaxel] results in increased expression of ABCG2 mRNA	20705681
D002945	Cisplatin	[Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 protein	21342274
D002945	Cisplatin	Cisplatin results in increased expression of ABCG2 mRNA	27392435
D002945	Cisplatin	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Cisplatin	21712253
D002945	Cisplatin	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Cisplatin	21833476
D002945	Cisplatin	[Proadifen co-treated with Cisplatin] results in increased expression of ABCG2 protein	26721606
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene metabolite results in decreased activity of ABCG2 protein	23169446
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate results in increased expression of ABCG2 mRNA	26924002
D004026	Dieldrin	Dieldrin results in increased expression of ABCG2 mRNA	24464585
D004041	Dietary Fats	Dietary Fats results in increased expression of ABCG2 mRNA	15238619
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of ABCG2 mRNA	19850644
D004051	Diethylhexyl Phthalate	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of ABCG2 mRNA]	19850644
C449540	diferuloylputrescine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased secretion of diferuloylputrescine metabolite"	20089784
C047225	difloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of difloxacin]"	21821808
C047225	difloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of difloxacin]"	21821808
C047225	difloxacin	ABCG2 protein polymorphism results in increased export of difloxacin	21821808
C047225	difloxacin	ABCG2 protein results in increased export of difloxacin	21821808
C072847	diflufenican	diflufenican inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D004077	Digoxin	Digoxin results in decreased activity of ABCG2 protein	15365089
D004117	Dimethoate	Dimethoate inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C076154	dimethomorph	dimethomorph inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of ABCG2 mRNA	17547211
C024629	dimethyl phthalate	dimethyl phthalate results in increased expression of ABCG2 mRNA	26924002
C018529	dithianone	dithianone inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C067311	docetaxel	[docetaxel results in decreased susceptibility to docetaxel] which results in decreased expression of ABCG2 mRNA	19944135
D004317	Doxorubicin	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Doxorubicin]	21712253
D004317	Doxorubicin	ABCG2 protein affects the susceptibility to Doxorubicin	18382425
D004317	Doxorubicin	ABCG2 protein affects the transport of Doxorubicin	17273774
D004317	Doxorubicin	ABCG2 protein results in decreased susceptibility to Doxorubicin	17938326
D004317	Doxorubicin	ABCG2 results in decreased abundance of and results in decreased susceptibility to Doxorubicin	19232821
D004317	Doxorubicin	Dactinomycin inhibits the reaction [Doxorubicin results in increased expression of ABCG2 mRNA]	20019844
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCG2 mRNA	18382425\|2001984
D004317	Doxorubicin	Doxorubicin results in increased expression of ABCG2 protein	18382425
D004317	Doxorubicin	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Doxorubicin	21712253
D004317	Doxorubicin	gefitinib inhibits the reaction [ABCG2 protein results in decreased susceptibility to Doxorubicin]	17938326
D004317	Doxorubicin	[[gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin	17938326
D004317	Doxorubicin	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Doxorubicin	21833476
D004317	Doxorubicin	sunitinib inhibits the reaction [ABCG2 results in decreased abundance of and results in decreased susceptibility to Doxorubicin]	19232821
D004317	Doxorubicin	ABCG2 results in decreased susceptibility to Doxorubicin	18451141
C095803	E 3040	ABCG2 protein affects the export of E 3040 analog	15598971
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein affects the transport of resveratrol]	17032904
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in increased transport of Sulpiride]	28597291
C083501	Elacridar	Elacridar inhibits the reaction [Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]]	17032904
C083501	Elacridar	Elacridar results in decreased activity of ABCG2 protein	15930306
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in decreased export of abacavir]	17437964
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]	17437964
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]	19056916
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Prazosin]	19056916
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
C083501	Elacridar	Elacridar inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]	18799806
C083501	Elacridar	Elacridar results in decreased activity of ABCG2 protein	18799806\|1901322
D004726	Endosulfan	Endosulfan results in decreased activity of ABCG2 protein	24464585
C052904	enrofloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of enrofloxacin]"	21821808
C052904	enrofloxacin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of enrofloxacin]"	21821808
C052904	enrofloxacin	ABCG2 protein binds to and results in increased transport of enrofloxacin	23652544
C052904	enrofloxacin	ABCG2 protein polymorphism results in increased export of enrofloxacin	21821808
C052904	enrofloxacin	ABCG2 protein results in increased export of enrofloxacin	21821808
C052904	enrofloxacin	ABCG2 protein binds to and results in increased transport of enrofloxacin	23652544
D015251	Epirubicin	ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D015251	Epirubicin	ABCG2 protein results in decreased susceptibility to Epirubicin	10606239
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased activity of ABCG2 protein	20149610
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of ABCG2 mRNA	18851785
D060754	Equol	"Equol inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
D060754	Equol	"Equol inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
D000069347	Erlotinib Hydrochloride	Erlotinib Hydrochloride inhibits the reaction [ABCG2 gene mutant form results in decreased susceptibility to Mitoxantrone]	18829547
D000069347	Erlotinib Hydrochloride	Erlotinib Hydrochloride inhibits the reaction [ABCG2 protein results in decreased susceptibility to Mitoxantrone]	18829547
D000069347	Erlotinib Hydrochloride	Erlotinib Hydrochloride inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
D000069347	Erlotinib Hydrochloride	Erlotinib Hydrochloride inhibits the reaction [ABCG2 results in increased export of Methotrexate]	19232821
C025483	estradiol-17 beta-glucuronide	ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide	18436619\|1882954
C025483	estradiol-17 beta-glucuronide	Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]	18436619
C025483	estradiol-17 beta-glucuronide	lapatinib inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]	18829547
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in decreased expression of ABCG2 mRNA	23707492
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in decreased expression of ABCG2 protein	23707492
D004964	Estriol	Estriol results in increased expression of ABCG2 mRNA	16849015\|1782385
D004964	Estriol	Estriol results in increased expression of ABCG2 protein	17823853
D004964	Estriol	fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 mRNA]	17823853
D004964	Estriol	fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 protein]	17823853
D004967	Estrogens	ABCG2 protein affects the transport of Estrogens	14683478
D004970	Estrone	Estrone results in increased expression of ABCG2 mRNA	16849015
C017296	estrone sulfate	ABCG2 protein affects the export of estrone sulfate	15901800
C017296	estrone sulfate	ABCG2 protein affects the transport of estrone sulfate	19505989
C017296	estrone sulfate	ABCG2 protein results in increased export of estrone sulfate	21483698
C017296	estrone sulfate	ABCG2 protein results in increased uptake of estrone sulfate	18834354\|2258138
C017296	estrone sulfate	Androstenedione inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
C017296	estrone sulfate	Estradiol inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
C017296	estrone sulfate	hippuric acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
C017296	estrone sulfate	Indican inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
C017296	estrone sulfate	Kynurenic Acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
C017296	estrone sulfate	Progesterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
C017296	estrone sulfate	Risperidone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	18834354
C017296	estrone sulfate	Testosterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
D000431	Ethanol	Ethanol results in decreased expression of ABCG2 mRNA	19167417
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ABCG2 mRNA	27765674
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of and results in decreased activity of ABCG2 protein	24945792
D004997	Ethinyl Estradiol	fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCG2 protein]	24945792
C024565	ethylene dichloride	ethylene dichloride results in decreased expression of ABCG2 mRNA	28189721
D005047	Etoposide	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]	21712253
D005047	Etoposide	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide	21712253
D000068338	Everolimus	ABCG2 protein affects the stability of Everolimus	24727322
D000068338	Everolimus	bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the stability of Everolimus]	24727322
D000068338	Everolimus	Everolimus inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]	24727322
D015025	Zearalenone	Zearalenone results in increased expression of ABCG2 mRNA	19580841
D015025	Zearalenone	Zearalenone results in decreased expression of ABCG2 mRNA	23707492
D015025	Zearalenone	Zearalenone results in decreased expression of ABCG2 protein	23707492
D015025	Zearalenone	Zearalenone results in increased expression of ABCG2 mRNA	22521637
D015025	Zearalenone	Zearalenone results in increased expression of ABCG2 protein	22521637
C111409	finrozole	[Aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCG2 protein	23402939
C111409	finrozole	[Aflatoxin B1 co-treated with finrozole] results in increased expression of ABCG2 mRNA	23402939
C043562	flavone	flavone results in increased expression of ABCG2 mRNA	17077187
C043562	flavone	flavone results in increased expression of ABCG2 protein	17077187
D047309	Flavones	Flavones analog results in decreased activity of ABCG2 protein	15930306
D005419	Flavonoids	Flavonoids results in decreased activity of ABCG2 protein	17093006
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased activity of ABCG2 protein	27475308
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCG2 mRNA	16381673
D015073	2-Acetylaminofluorene	NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCG2 mRNA]	16381673
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCG2 mRNA	12819005\|1766924
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of ABCG2 protein	17538966
D005472	Fluorouracil	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Fluorouracil]	21712253
D005472	Fluorouracil	ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]	12576456
D005472	Fluorouracil	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Fluorouracil	21712253
D005472	Fluorouracil	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil	21833476
D005485	Flutamide	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D005485	Flutamide	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
D005492	Folic Acid	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] inhibits the reaction [Folic Acid deficiency results in decreased susceptibility to Mitoxantrone]"	18623116
D005492	Folic Acid	ABCG2 protein affects the transport of Folic Acid	17032904
D005492	Folic Acid	Folic Acid affects the localization of and affects the expression of ABCG2 protein	15657365
D005492	Folic Acid	Folic Acid deficiency results in increased expression of ABCG2 mRNA	18623116
D005492	Folic Acid	Folic Acid deficiency results in increased expression of ABCG2 protein	18623116
D005492	Folic Acid	[Folic Acid deficiency results in increased expression of ABCG2 protein] which results in decreased susceptibility to Mitoxantrone	18623116
D005492	Folic Acid	Protons promotes the reaction [ABCG2 protein results in increased transport of Folic Acid]	17032904
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABCG2 gene	20938992
D005492	Folic Acid	Folic Acid results in decreased expression of ABCG2 mRNA	19552531
D005492	Folic Acid	Folic Acid results in decreased expression of ABCG2 protein	19552531
C070081	fulvestrant	ABCG2 affects the susceptibility to fulvestrant	24169358
C070081	fulvestrant	fulvestrant affects the reaction [4-nonylphenol results in decreased expression of ABCG2 protein]	27036933
C070081	fulvestrant	fulvestrant affects the reaction [bisphenol A results in decreased expression of ABCG2 protein]	27036933
C070081	fulvestrant	fulvestrant affects the reaction [Estradiol results in decreased expression of ABCG2 protein]	27036933
C070081	fulvestrant	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
C070081	fulvestrant	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
C070081	fulvestrant	fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 mRNA]	17823853
C070081	fulvestrant	fulvestrant inhibits the reaction [Estriol results in increased expression of ABCG2 protein]	17823853
C070081	fulvestrant	fulvestrant inhibits the reaction [Genistein results in decreased expression of ABCG2 protein]	26850786
C070081	fulvestrant	fulvestrant inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCG2 protein]	24945792
C039281	furan	furan results in increased expression of ABCG2 mRNA	25539665
C419708	gefitinib	gefitinib inhibits the reaction [ABCG2 protein results in decreased susceptibility to Doxorubicin]	17938326
C419708	gefitinib	[gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein	17938326
C419708	gefitinib	[[gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin	17938326
D019833	Genistein	fulvestrant inhibits the reaction [Genistein results in decreased expression of ABCG2 protein]	26850786
D019833	Genistein	Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26850786
D019833	Genistein	Genistein inhibits the reaction [ABCG2 protein results in increased export of Glyburide]	26850786
D019833	Genistein	Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]	26850786
D019833	Genistein	Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide]	26850786
D019833	Genistein	Genistein results in decreased expression of ABCG2 mRNA	26850786
D019833	Genistein	Genistein results in decreased expression of ABCG2 protein	26850786
D019833	Genistein	[Genistein co-treated with daidzein] inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	19754918
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in increased expression of ABCG2 mRNA alternative form	20804740
C049864	ginsenoside Re	ABCG2 protein results in increased transport of ginsenoside Re	25297453
C049864	ginsenoside Re	ABCG2 protein results in increased transport of ginsenoside Re	25297453
C035054	ginsenoside Rg1	ABCG2 protein results in increased transport of ginsenoside Rg1	25297453
C035054	ginsenoside Rg1	ABCG2 protein results in increased transport of ginsenoside Rg1	25297453
D020719	Glucuronides	ABCG2 protein affects the export of Glucuronides	15749994
D005978	Glutathione	"2',5'-dihydroxychalcone promotes the reaction [ABCG2 protein results in increased export of Glutathione]"	20332504
D005978	Glutathione	ABCG2 protein results in increased export of Glutathione	20332504
D005978	Glutathione	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of Glutathione]	20332504
D005905	Glyburide	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Glyburide]"	26850786
D005905	Glyburide	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide]"	26850786
D005905	Glyburide	ABCG2 protein polymorphism results in decreased export of Glyburide	26850786
D005905	Glyburide	ABCG2 protein results in increased export of Glyburide	26850786
D005905	Glyburide	Genistein inhibits the reaction [ABCG2 protein results in increased export of Glyburide]	26850786
D005905	Glyburide	Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide]	26850786
D006034	Glycyrrhetinic Acid	Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]	18436619
D006220	Haloperidol	Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D006533	Heptachlor	Heptachlor results in decreased activity of ABCG2 protein	24464585
C030514	hippuric acid	hippuric acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
D017313	Fenretinide	Fenretinide results in increased expression of ABCG2 mRNA	28973697
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of ABCG2 mRNA	26519223
D006923	Hymecromone	ABCG2 protein affects the export of Hymecromone analog	15598971
C058309	hypaconitine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine"	23200901
C058309	hypaconitine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of hypaconitine"	23200901
C058309	hypaconitine	ABCG2 protein results in increased transport of hypaconitine	23200901
D000068877	Imatinib Mesylate	ABCG2 protein results in decreased susceptibility to Imatinib Mesylate	24954033
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of ABCG2 mRNA	15970668
D000068877	Imatinib Mesylate	Imatinib Mesylate results in increased expression of and results in increased activity of ABCG2 protein	15970668
D000068877	Imatinib Mesylate	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]"	19056916
D000068877	Imatinib Mesylate	ABCG2 protein results in increased export of Imatinib Mesylate	19056916
D000068877	Imatinib Mesylate	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]	19056916
D000068877	Imatinib Mesylate	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]	19056916
D007200	Indican	Indican inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
C016517	indole-3-carbinol	indole-3-carbinol results in increased expression of ABCG2 mRNA	17077187
C075954	indolo(3,2-b)carbazole	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA]"	15917307
C075954	indolo(3,2-b)carbazole	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 protein]"	15917307
C075954	indolo(3,2-b)carbazole	"benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA]"	17077187
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]"	15917307
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA"	15917307\|1707718
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole results in increased expression of and results in increased activity of ABCG2 protein"	15917307
D007306	Insecticides	Insecticides results in decreased activity of ABCG2 protein	23169446
C008161	ioxynil	ioxynil inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
C051890	irinotecan	ABCG2 affects the susceptibility to irinotecan	16542215
C051890	irinotecan	ABCG2 gene polymorphism affects the susceptibility to and affects the metabolism of irinotecan	15801936
C051890	irinotecan	ABCG2 mRNA results in increased susceptibility to irinotecan	15239142
C051890	irinotecan	ABCG2 protein affects the export of irinotecan	15655543\|1569540
C051890	irinotecan	ABCG2 protein affects the metabolism of irinotecan	15801936
C051890	irinotecan	ABCG2 protein results in decreased susceptibility to irinotecan	10606239
C051890	irinotecan	ABCG2 protein results in increased susceptibility to irinotecan	16954373
C051890	irinotecan	ABCG2 protein results in increased transport of irinotecan	12869632
C051890	irinotecan	ABCG2 results in decreased susceptibility to irinotecan	12869632
C051890	irinotecan	Reserpine inhibits the reaction [ABCG2 protein results in increased transport of irinotecan]	12869632
C051890	irinotecan	ABCG2 protein affects the metabolism of irinotecan	24727322
C051890	irinotecan	bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]	24727322
C051890	irinotecan	Everolimus inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]	24727322
C051890	irinotecan	ABCG2 protein results in increased export of irinotecan	16271446
D007501	Iron	ABCG2 protein affects the metabolism of Iron	17194590
D019266	Iron, Dietary	"Iron, Dietary affects the expression of ABCG2 mRNA"	15637178
D007529	Isoflavones	Isoflavones inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	19754918
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	"isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein"	25844889
C000603302	isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate	"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCG2 protein] which results in increased uptake of abacavir"	25844889
D007545	Isoproterenol	Isoproterenol results in increased expression of ABCG2 mRNA	20003209
D007559	Ivermectin	ABCG2 protein polymorphism affects the susceptibility to Ivermectin	21821808
D007559	Ivermectin	[ABCG2 protein polymorphism affects the susceptibility to Ivermectin] which affects the export of Mitoxantrone	21821808
D007559	Ivermectin	Ivermectin inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	21821808
D007559	Ivermectin	Ivermectin results in increased expression of ABCG2 mRNA	24998875
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in increased expression of ABCG2 mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of ABCG2 mRNA	26752646
D007608	Kainic Acid	Kainic Acid results in increased expression of ABCG2 mRNA	17997037
D007736	Kynurenic Acid	Kynurenic Acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate]	21483698
C490728	lapatinib	lapatinib inhibits the reaction [ABCG2 gene mutant form results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [ABCG2 protein results in decreased susceptibility to Topotecan]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]	18829547
C490728	lapatinib	lapatinib inhibits the reaction [azidoprazosin binds to ABCG2 protein]	18829547
C490728	lapatinib	lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]	18829547
C008261	lead acetate	lead acetate results in increased expression of ABCG2 mRNA	22641619
D001556	Lindane	Lindane results in increased expression of ABCG2 mRNA	24464585
C433788	lipopolysaccharide, E. coli O26-B6	"lipopolysaccharide, E. coli O26-B6 results in decreased expression of ABCG2 mRNA"	22942241
C433788	lipopolysaccharide, E. coli O26-B6	"lipopolysaccharide, E. coli O26-B6 results in decreased expression of ABCG2 protein"	22942241
D008070	Lipopolysaccharides	Lipopolysaccharides affects the expression of ABCG2 mRNA	28070326
D008070	Lipopolysaccharides	Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of ABCG2 mRNA]	28070326
D008070	Lipopolysaccharides	[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in decreased expression of ABCG2 mRNA	20816778
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of ABCG2 mRNA	20977460
D008095	Lithocholic Acid	NFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCG2 mRNA]	20977460
C010480	lupeol	lupeol results in decreased expression of ABCG2 protein	20979057
D047311	Luteolin	Luteolin affects the activity of ABCG2 protein	20403331
C412309	ME 3229	ABCG2 protein affects the transport of ME 3229 metabolite	15846469
C117060	ME 3277	ABCG2 protein affects the transport of ME 3277	15846469
C042720	mercuric bromide	mercuric bromide results in increased expression of ABCG2 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of ABCG2 mRNA	24118919
D008627	Mercuric Chloride	ABCG2 gene mutant form results in increased susceptibility to Mercuric Chloride	25868844
D008627	Mercuric Chloride	ABCG2 protein affects the export of Mercuric Chloride	25868844
D008628	Mercury	Mercury results in increased expression of ABCG2 mRNA	17547211
C019470	mesaconitine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of mesaconitine"	23200901
C019470	mesaconitine	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] which results in decreased transport of mesaconitine"	23200901
C019470	mesaconitine	ABCG2 protein results in increased transport of mesaconitine	23200901
D008694	Methamphetamine	[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA	19564919
D008694	Methamphetamine	Methamphetamine results in decreased expression of ABCG2 mRNA	19564919
D008714	Methiocarb	Methiocarb inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ABCG2 gene	20938992
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCG2 mRNA	17640958\|2438491
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCG2 protein	17640958
D008727	Methotrexate	ABCG2 gene polymorphism affects the susceptibility to Methotrexate	21064136
D008727	Methotrexate	ABCG2 gene SNP affects the susceptibility to Methotrexate	18256692
D008727	Methotrexate	ABCG2 protein affects the transport of Methotrexate	17032904
D008727	Methotrexate	ABCG2 protein affects the transport of Methotrexate analog	17032904
D008727	Methotrexate	ABCG2 protein results in decreased susceptibility to Methotrexate	21971989
D008727	Methotrexate	ABCG2 protein results in increased export of and results in decreased susceptibility to Methotrexate	17032904
D008727	Methotrexate	ABCG2 protein results in increased export of Methotrexate	18829547\|2197198
D008727	Methotrexate	ABCG2 protein results in increased transport of Methotrexate	19114588
D008727	Methotrexate	ABCG2 results in increased export of Methotrexate	19232821
D008727	Methotrexate	Erlotinib Hydrochloride inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
D008727	Methotrexate	Erlotinib Hydrochloride inhibits the reaction [ABCG2 results in increased export of Methotrexate]	19232821
D008727	Methotrexate	lapatinib inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
D008727	Methotrexate	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D008727	Methotrexate	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of Glutathione]	20332504
D008727	Methotrexate	Methotrexate results in increased expression of ABCG2 mRNA	24736981
D008727	Methotrexate	Methotrexate results in increased expression of ABCG2 protein	24736981
D008727	Methotrexate	Protons promotes the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Methotrexate]	17032904
D008727	Methotrexate	resveratrol-4'-O-glucuronide inhibits the reaction [ABCG2 protein results in increased transport of Methotrexate]	19114588
D008727	Methotrexate	resveratrol analog inhibits the reaction [ABCG2 protein results in increased transport of Methotrexate]	19114588
D008727	Methotrexate	sunitinib inhibits the reaction [ABCG2 results in increased export of Methotrexate]	19232821
D008727	Methotrexate	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
D008727	Methotrexate	ABCG2 mRNA results in decreased susceptibility to Methotrexate	16918715
D008727	Methotrexate	Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D008727	Methotrexate	ABCG2 protein results in increased transport of Methotrexate	21737571
C042921	methotrexate-alpha glutamate	Protons promotes the reaction [ABCG2 protein results in increased export of methotrexate-alpha glutamate]	17032904
D008730	Methoxsalen	Methoxsalen results in decreased activity of ABCG2 protein	29079042
D008730	Methoxsalen	[Methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone	29079042
D008730	Methoxsalen	Methoxsalen results in increased expression of ABCG2 mRNA	29079042
D008730	Methoxsalen	Novobiocin inhibits the reaction [Methoxsalen results in decreased activity of ABCG2 protein]	29079042
D008730	Methoxsalen	Novobiocin inhibits the reaction [[Methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
D008748	Methylcholanthrene	ABCG2 5' UTR affects the susceptibility to Methylcholanthrene	20804740
D008748	Methylcholanthrene	AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]	20804740
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]	20804740
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCG2	23081912
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCG2 mRNA	20804740
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCG2 mRNA alternative form	20804740
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of ABCG2 protein	20804740
C004925	methylmercuric chloride	ABCG2 protein results in decreased susceptibility to methylmercuric chloride	24118919
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of ABCG2 mRNA	24118919
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of ABCG2 mRNA	28536007
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of ABCG2 protein"	19732497
D008775	Methylprednisolone	"Methylprednisolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
C027837	milbemycin	ABCG2 protein results in increased export of milbemycin	19428349
C027837	milbemycin	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of milbemycin]	19428349
C027837	milbemycin	ABCG2 protein results in increased export of milbemycin	19428349
D008942	Mitoxantrone	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of Mitoxantrone]"	21821808
D008942	Mitoxantrone	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	21821808
D008942	Mitoxantrone	[ABCG2 protein polymorphism affects the susceptibility to Ivermectin] which affects the export of Mitoxantrone	21821808
D008942	Mitoxantrone	ABCG2 protein polymorphism results in increased export of Mitoxantrone	21821808
D008942	Mitoxantrone	ABCG2 protein results in increased export of Mitoxantrone	21821808
D008942	Mitoxantrone	Ivermectin inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	21821808
D008942	Mitoxantrone	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	16442095
D008942	Mitoxantrone	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]"	18834354
D008942	Mitoxantrone	"[3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester results in decreased activity of ABCG2 protein] inhibits the reaction [Folic Acid deficiency results in decreased susceptibility to Mitoxantrone]"	18623116
D008942	Mitoxantrone	[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone	29079042
D008942	Mitoxantrone	ABCG2 gene mutant form results in increased export of and results in decreased susceptibility to Mitoxantrone	18829547
D008942	Mitoxantrone	ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Mitoxantrone]	21712253
D008942	Mitoxantrone	ABCG2 protein affects the export of Mitoxantrone	15695404
D008942	Mitoxantrone	ABCG2 protein affects the susceptibility to Mitoxantrone	24994473
D008942	Mitoxantrone	ABCG2 protein affects the transport of Mitoxantrone	15875186\|1703290
D008942	Mitoxantrone	ABCG2 protein affects the uptake of Mitoxantrone	15640379
D008942	Mitoxantrone	ABCG2 protein results in decreased abundance of Mitoxantrone	12869632
D008942	Mitoxantrone	ABCG2 protein results in decreased susceptibility to Mitoxantrone	10606239\|1703290
D008942	Mitoxantrone	ABCG2 protein results in increased export of and results in decreased susceptibility to Mitoxantrone	18829547
D008942	Mitoxantrone	ABCG2 protein results in increased export of Mitoxantrone	16442095\|1663679
D008942	Mitoxantrone	ABCG2 protein results in increased susceptibility to Mitoxantrone	16954373
D008942	Mitoxantrone	ABCG2 protein results in increased transport of Mitoxantrone	18834354\|2289205
D008942	Mitoxantrone	Beclomethasone inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
D008942	Mitoxantrone	Cadmium Chloride inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	22892056
D008942	Mitoxantrone	Chlorpromazine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	chrysin inhibits the reaction [ABCG2 protein results in increased secretion of Mitoxantrone]	17093006
D008942	Mitoxantrone	Clozapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	Cyclosporine inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16636798
D008942	Mitoxantrone	Dactinomycin inhibits the reaction [Mitoxantrone results in increased expression of ABCG2 mRNA]	20019844
D008942	Mitoxantrone	desisobutyrylciclesonide inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
D008942	Mitoxantrone	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Mitoxantrone	21712253
D008942	Mitoxantrone	Erlotinib Hydrochloride inhibits the reaction [ABCG2 gene mutant form results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	Erlotinib Hydrochloride inhibits the reaction [ABCG2 protein results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	[Folic Acid deficiency results in increased expression of ABCG2 protein] which results in decreased susceptibility to Mitoxantrone	18623116
D008942	Mitoxantrone	Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	lapatinib inhibits the reaction [ABCG2 gene mutant form results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	lapatinib inhibits the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	[Methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone	29079042
D008942	Mitoxantrone	Mitoxantrone results in increased expression of ABCG2 mRNA	15239124\|2001984
D008942	Mitoxantrone	Mitoxantrone results in increased expression of ABCG2 protein	15239124
D008942	Mitoxantrone	Mometasone Furoate inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
D008942	Mitoxantrone	Novobiocin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
D008942	Mitoxantrone	Novobiocin inhibits the reaction [[Methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
D008942	Mitoxantrone	olanzapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	oxfendazole inhibits the reaction [ABCG2 protein affects the transport of Mitoxantrone]	15703302
D008942	Mitoxantrone	Paliperidone Palmitate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	Protons promotes the reaction [ABCG2 protein results in decreased susceptibility to Mitoxantrone]	17032904
D008942	Mitoxantrone	Quetiapine Fumarate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	Risperidone inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D008942	Mitoxantrone	tryptoquivaline inhibits the reaction [ABCG2 gene mutant form results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	tryptoquivaline inhibits the reaction [ABCG2 protein affects the uptake of Mitoxantrone]	15640379
D008942	Mitoxantrone	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
D008942	Mitoxantrone	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	19428349
D008942	Mitoxantrone	oxfendazole inhibits the reaction [ABCG2 protein affects the transport of Mitoxantrone]	15703302
D008942	Mitoxantrone	ABCG2 protein affects the export of Mitoxantrone	15773906
D008942	Mitoxantrone	"3-(4-chloro-3-nitrolphenyl)-1,2,3-oxadiazolium-5-olate inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	27417255
D008942	Mitoxantrone	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]"	27417255
D008942	Mitoxantrone	ABCG2 protein results in increased export of Mitoxantrone	27417255
D000068656	Mometasone Furoate	Mometasone Furoate inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	16442095
D000068656	Mometasone Furoate	Mometasone Furoate results in increased activity of ABCG2 protein	16442095
C533978	monepantel	monepantel inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C533978	monepantel	monepantel inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C553923	monepantel sulfone	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C553923	monepantel sulfone	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C553923	monepantel sulfone	monepantel sulfone inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C091888	monoisoamyl-2,3-dimercaptosuccinate	"monoisoamyl-2,3-dimercaptosuccinate results in decreased expression of ABCG2 mRNA"	19615344
C517284	monomethyl phthalate	monomethyl phthalate results in increased expression of ABCG2 mRNA	26924002
D009020	Morphine	[Morphine co-treated with Naloxone] results in increased expression of ABCG2 mRNA	26554626
C420606	mulberroside A	mulberroside A inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C560625	N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine	N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Benzo(a)pyrene results in increased expression of ABCG2 protein]	22912337
D009270	Naloxone	[Morphine co-treated with Naloxone] results in increased expression of ABCG2 mRNA	26554626
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of ABCG2 mRNA"	25620056
D009288	Naproxen	Naproxen affects the activity of ABCG2 protein	18581209
D009288	Naproxen	Naproxen affects the expression of ABCG2 protein	18581209
C498045	NCX 4040	NCX 4040 results in increased expression of ABCG2 mRNA	20188076
D019888	Nelfinavir	Nelfinavir results in decreased activity of ABCG2 protein	16041239
D019888	Nelfinavir	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
D019888	Nelfinavir	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Imatinib Mesylate]	19056916
D019888	Nelfinavir	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
D009538	Nicotine	Nicotine results in increased expression of ABCG2 mRNA	17997037
C012655	nimesulide	nimesulide results in decreased activity of ABCG2 protein	18581209
C012655	nimesulide	nimesulide results in decreased expression of ABCG2 protein	18581209
D009582	Nitrofurantoin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein polymorphism results in increased export of Nitrofurantoin]"	21821808
D009582	Nitrofurantoin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Nitrofurantoin]"	21821808
D009582	Nitrofurantoin	ABCG2 protein polymorphism results in increased export of Nitrofurantoin	21821808
D009582	Nitrofurantoin	ABCG2 protein results in increased export of Nitrofurantoin	21821808
D009582	Nitrofurantoin	ABCG2 protein affects the transport of Nitrofurantoin	15709111
D009582	Nitrofurantoin	ABCG2 protein results in increased transport of Nitrofurantoin	17093006
D009582	Nitrofurantoin	chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	17093006
D009582	Nitrofurantoin	Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D009582	Nitrofurantoin	ABCG2 protein affects the abundance of Nitrofurantoin	17785426
D009582	Nitrofurantoin	ABCG2 protein affects the transport of Nitrofurantoin	15709111\|1572245
D009582	Nitrofurantoin	ABCG2 protein results in increased export of Nitrofurantoin	15709111
D009582	Nitrofurantoin	ABCG2 protein results in increased secretion of Nitrofurantoin	15709111
D009582	Nitrofurantoin	ABCG2 protein results in increased transport of Nitrofurantoin	17093006
D009582	Nitrofurantoin	chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	17093006
D009582	Nitrofurantoin	Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	26907376
D009582	Nitrofurantoin	ABCG2 protein results in increased transport of Nitrofurantoin	19754918
D009582	Nitrofurantoin	[Genistein co-treated with daidzein] inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	19754918
D009582	Nitrofurantoin	Isoflavones inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]	19754918
D009582	Nitrofurantoin	ABCG2 affects the susceptibility to Nitrofurantoin	19105722
D009582	Nitrofurantoin	ABCG2 protein affects the abundance of Nitrofurantoin	18799806
D009582	Nitrofurantoin	ABCG2 results in increased secretion of Nitrofurantoin	19105722
D009582	Nitrofurantoin	chrysin inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]	19732493
D009582	Nitrofurantoin	Elacridar inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]	18799806
C072936	notoginsenoside R1	ABCG2 protein results in increased transport of notoginsenoside R1	25297453
C072936	notoginsenoside R1	ABCG2 protein results in increased transport of notoginsenoside R1	25297453
D009675	Novobiocin	Novobiocin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCG2 protein]	29079042
D009675	Novobiocin	Novobiocin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
D009675	Novobiocin	Novobiocin inhibits the reaction [Methoxsalen results in decreased activity of ABCG2 protein]	29079042
D009675	Novobiocin	Novobiocin inhibits the reaction [[Methoxsalen results in decreased activity of ABCG2 protein] which results in decreased export of and results in increased abundance of Mitoxantrone]	29079042
D009675	Novobiocin	[Novobiocin results in decreased activity of ABCG2 protein] which results in decreased secretion of Rosuvastatin Calcium	19853032
C025589	ochratoxin A	ABCG2 protein affects the susceptibility to ochratoxin A	28532671
C025589	ochratoxin A	ABCG2 protein affects the transport of ochratoxin A	28532671
C025589	ochratoxin A	ABCG2 protein results in decreased susceptibility to ochratoxin A	28532671
C025589	ochratoxin A	ABCG2 protein results in decreased transport of ochratoxin A	28532671
C025589	ochratoxin A	ochratoxin A results in decreased expression of ABCG2 mRNA	29126803
C025589	ochratoxin A	ochratoxin A results in increased expression of ABCG2 mRNA	29126803
D019301	Oleic Acid	Oleic Acid results in increased expression of ABCG2 mRNA	22819932
C076029	olanzapine	olanzapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D009828	Oleanolic Acid	Oleanolic Acid results in increased expression of ABCG2 mRNA	23948738
C026209	oltipraz	oltipraz promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]	15917307
C026209	oltipraz	oltipraz results in increased activity of ABCG2 protein	15917307
C026209	oltipraz	oltipraz results in increased expression of ABCG2 mRNA	16837569
D009853	Omeprazole	Omeprazole results in increased expression of ABCG2 mRNA alternative form	20804740
D009853	Omeprazole	Omeprazole results in increased expression of ABCG2 protein	20804740
C016340	o,p'-DDT	"o,p'-DDT results in decreased activity of ABCG2 protein"	23169446
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of ABCG2 mRNA"	24464585
D008939	Mitotane	Mitotane results in increased expression of ABCG2 mRNA	25542188
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in decreased expression of ABCG2 mRNA	25729387
C030110	oxaliplatin	oxaliplatin results in decreased expression of ABCG2 mRNA	25729387
C011030	oxfendazole	ABCG2 protein affects the transport of oxfendazole	15703302
C011030	oxfendazole	oxfendazole inhibits the reaction [ABCG2 protein affects the transport of Mitoxantrone]	15703302
C011030	oxfendazole	oxfendazole results in decreased activity of ABCG2 protein	15703302
C011030	oxfendazole	ABCG2 protein affects the transport of oxfendazole	15703302
C011030	oxfendazole	oxfendazole inhibits the reaction [ABCG2 protein affects the transport of Mitoxantrone]	15703302
C011030	oxfendazole	oxfendazole results in decreased activity of ABCG2 protein	15703302
D010100	Oxygen	Oxygen deficiency results in increased expression of ABCG2 protein	23725749
D010126	Ozone	Ozone results in decreased expression of ABCG2 mRNA	16183385
D017239	Paclitaxel	[Cisplatin co-treated with Paclitaxel] results in increased expression of ABCG2 mRNA	20705681
D017239	Paclitaxel	[ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Paclitaxel	21712253
D017239	Paclitaxel	Paclitaxel results in decreased expression of ABCG2 mRNA	21833476
D017239	Paclitaxel	Paclitaxel results in decreased expression of ABCG2 protein	21833476
D017239	Paclitaxel	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Cisplatin	21833476
D017239	Paclitaxel	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Doxorubicin	21833476
D017239	Paclitaxel	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Fluorouracil	21833476
D017239	Paclitaxel	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine	21833476
D000068882	Paliperidone Palmitate	Paliperidone Palmitate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C064276	pantoprazole	pantoprazole inhibits the reaction [ABCG2 protein affects the transport of 7-hydroxymethotrexate]	17032904
D010269	Paraquat	Paraquat results in increased expression of ABCG2 mRNA	12595580
D052638	Particulate Matter	Particulate Matter results in increased expression of ABCG2 mRNA	25803276\|2884618
D052638	Particulate Matter	Particulate Matter results in increased expression of ABCG2 protein	25803276\|2884618
D052638	Particulate Matter	Particulate Matter results in increased expression of ABCG2 protein	18474546
C584865	perfluorononanoic acid	perfluorononanoic acid results in increased expression of ABCG2 mRNA	29112762
C101814	perfluoro-n-undecanoic acid	perfluoro-n-undecanoic acid results in increased expression of ABCG2 mRNA	23602845
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in increased expression of ABCG2 mRNA	19162173
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased activity of ABCG2 protein	24014645
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of ABCG2 mRNA	19162173
C023036	perfluorooctanoic acid	ABCG2 protein results in increased transport of perfluorooctanoic acid	24014645
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased activity of ABCG2 protein	23435180\|2401464
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of ABCG2 mRNA	23435180
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of ABCG2 protein	23435180
D026023	Permethrin	Permethrin results in decreased activity of ABCG2 protein	23169446
D010634	Phenobarbital	Phenobarbital affects the expression of ABCG2 mRNA	19159669
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCG2 mRNA	16837569\|1908454
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCG2 protein	16837569
D010634	Phenobarbital	Phenobarbital results in increased expression of ABCG2 mRNA	27160211
D010634	Phenobarbital	Phenobarbital results in decreased expression of ABCG2 mRNA	20607812
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of ABCG2 mRNA	26272509
C032623	pheophorbide a	ABCG2 protein results in increased export of pheophorbide a analog	25542188
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCG2 mRNA	19710929
C006253	pirinixic acid	pirinixic acid results in increased expression of ABCG2 mRNA	17426115\|1830175
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in increased expression of ABCG2 mRNA]	20059764
C108475	pitavastatin	ABCG2 protein affects the transport of pitavastatin	15955871
C108475	pitavastatin	ABCG2 protein affects the transport of pitavastatin	15955871
D010936	Plant Extracts	Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of ABCG2 mRNA]	28070326
C422648	pluronic block copolymer p85	pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of abacavir]	19056916
C422648	pluronic block copolymer p85	pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
C058229	polydatin	polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of ABCG2 mRNA	17547211
C489337	potassium oxonate	4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	Allopurinol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	mulberroside A inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	potassium oxonate results in increased expression of ABCG2 protein	22865646
C489337	potassium oxonate	Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C489337	potassium oxonate	resveratrol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
D017035	Pravastatin	ABCG2 protein affects the export of Pravastatin	15901800
D017035	Pravastatin	Pravastatin results in increased activity of ABCG2 protein	27475308
D011224	Prazosin	6-OH-BDE-47 inhibits the reaction [ABCG2 protein results in increased export of Prazosin]	28031414
D011224	Prazosin	ABCG2 protein results in increased export of Prazosin	28031414
D011224	Prazosin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Prazosin]"	19056916
D011224	Prazosin	ABCG2 protein affects the transport of Prazosin	18322075
D011224	Prazosin	ABCG2 protein results in increased export of Prazosin	19056916
D011224	Prazosin	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Prazosin]	19056916
D011335	Proadifen	[Proadifen co-treated with Cisplatin] results in increased expression of ABCG2 protein	26721606
D011339	Probenecid	Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C045362	prochloraz	prochloraz results in increased expression of ABCG2 mRNA	23081912
C045362	prochloraz	prochloraz results in increased expression of ABCG2 protein	23081912
C045362	prochloraz	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C045362	prochloraz	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]	24389113
C045362	prochloraz	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz results in increased expression of ABCG2 mRNA]	24389113
C045362	prochloraz	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
C045362	prochloraz	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]"	24389113
C045362	prochloraz	prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C045362	prochloraz	prochloraz results in increased activity of ABCG2 protein	24389113
C045362	prochloraz	prochloraz results in increased expression of ABCG2 mRNA	24389113
C045362	prochloraz	salicylamide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C045362	prochloraz	salicylamide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]	24389113
C045362	prochloraz	salicylamide inhibits the reaction [prochloraz results in increased expression of ABCG2 mRNA]	24389113
C045362	prochloraz	prochloraz results in decreased expression of ABCG2 mRNA	27028005
D011374	Progesterone	Progesterone results in decreased expression of ABCG2 mRNA	20631399
D011374	Progesterone	Progesterone affects the expression of ABCG2	18086804
D011374	Progesterone	Progesterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
D011374	Progesterone	Progesterone inhibits the reaction [Estradiol results in increased expression of ABCG2]	16849015
D011374	Progesterone	Progesterone results in decreased activity of ABCG2 protein	22581381
C033205	propamocarb	propamocarb inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D011522	Protons	Elacridar inhibits the reaction [Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in decreased susceptibility to Mitoxantrone]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased export of 7-hydroxymethotrexate]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Methotrexate]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased export of methotrexate-alpha glutamate]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased transport of Folic Acid]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased transport of Topotecan]	17032904
D011522	Protons	Protons promotes the reaction [ABCG2 protein results in increased transport of Topotecan]	17032904
C107773	pterostilbene	pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
D011794	Quercetin	AHR protein promotes the reaction [Quercetin results in increased expression of ABCG2 protein]	17077187
D011794	Quercetin	Quercetin affects the expression of ABCG2 mRNA	21632981
D011794	Quercetin	Quercetin results in decreased expression of ABCG2 mRNA	18624906
D011794	Quercetin	Quercetin results in decreased expression of ABCG2 protein	18624906
D011794	Quercetin	Quercetin results in increased expression of ABCG2 mRNA	17077187
D011794	Quercetin	Quercetin results in increased expression of ABCG2 protein	17077187
D011794	Quercetin	ABCG2 protein affects the export of Quercetin	15749994
D011794	Quercetin	ABCG2 protein affects the export of Quercetin metabolite	15749994
D000069348	Quetiapine Fumarate	Quetiapine Fumarate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D012110	Reserpine	Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
D012110	Reserpine	Reserpine inhibits the reaction [ABCG2 protein results in increased transport of irinotecan]	12869632
C100036	resmethrin	resmethrin results in decreased activity of ABCG2 protein	23169446
C059514	resveratrol	ABCG2 protein affects the transport of resveratrol	17032904
C059514	resveratrol	ABCG2 protein results in increased transport of resveratrol metabolite	19114588
C059514	resveratrol	AHR protein promotes the reaction [resveratrol results in increased expression of ABCG2 protein]	17077187
C059514	resveratrol	Elacridar inhibits the reaction [ABCG2 protein affects the transport of resveratrol]	17032904
C059514	resveratrol	Elacridar inhibits the reaction [Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]]	17032904
C059514	resveratrol	Protons promotes the reaction [ABCG2 protein results in increased export of resveratrol]	17032904
C059514	resveratrol	resveratrol analog inhibits the reaction [ABCG2 protein results in increased transport of Methotrexate]	19114588
C059514	resveratrol	resveratrol results in decreased expression of ABCG2 mRNA	21304978
C059514	resveratrol	resveratrol results in decreased expression of ABCG2 mRNA alternative form	20804740
C059514	resveratrol	resveratrol results in increased expression of ABCG2 mRNA	17077187\|2080474
C059514	resveratrol	resveratrol results in increased expression of ABCG2 protein	17077187
C059514	resveratrol	ABCG2 protein results in increased transport of resveratrol metabolite	19114588
C059514	resveratrol	resveratrol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]	22865646
C499731	resveratrol-4'-O-glucuronide	ABCG2 protein results in increased transport of resveratrol-4'-O-glucuronide	19114588
C499731	resveratrol-4'-O-glucuronide	resveratrol-4'-O-glucuronide inhibits the reaction [ABCG2 protein results in increased transport of Methotrexate]	19114588
D012293	Rifampin	Rifampin results in increased expression of ABCG2 mRNA	16837569\|2719975
C447879	rimsulfuron	rimsulfuron inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D018967	Risperidone	Risperidone inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]	18834354
D018967	Risperidone	Risperidone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	18834354
C089730	rosiglitazone	rosiglitazone inhibits the reaction [T 0070907 results in decreased expression of ABCG2 mRNA]	27879033
C089730	rosiglitazone	rosiglitazone results in increased expression of ABCG2 mRNA	27879033
C089730	rosiglitazone	rosiglitazone results in increased expression of ABCG2 protein	27879033
D000068718	Rosuvastatin Calcium	[Novobiocin results in decreased activity of ABCG2 protein] which results in decreased secretion of Rosuvastatin Calcium	19853032
C031060	salicylamide	salicylamide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C031060	salicylamide	salicylamide inhibits the reaction [prochloraz results in increased activity of ABCG2 protein]	24389113
C031060	salicylamide	salicylamide inhibits the reaction [prochloraz results in increased expression of ABCG2 mRNA]	24389113
C031060	salicylamide	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
C031060	salicylamide	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]	24389113
C031060	salicylamide	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	24389113
C534628	SCH 23390	[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA	19564919
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of ABCG2 mRNA	23806026
D012838	Silymarin	AHR protein promotes the reaction [Silymarin results in increased expression of ABCG2 protein]	17077187
D012838	Silymarin	Silymarin results in increased expression of ABCG2 protein	17077187
D012906	Smoke	decitabine inhibits the reaction [Smoke results in decreased expression of ABCG2 mRNA]	21095227
C009277	sodium arsenate	sodium arsenate results in increased expression of ABCG2 mRNA	21795629
C017947	sodium arsenite	sodium arsenite affects the expression of ABCG2 mRNA	20056578
C017947	sodium arsenite	sodium arsenite affects the splicing of ABCG2 mRNA	25879800
C017947	sodium arsenite	sodium arsenite results in decreased expression of ABCG2 mRNA	19615344
C017947	sodium arsenite	sodium arsenite results in increased expression of ABCG2 mRNA	25879800
D017693	Sodium Bicarbonate	Sodium Bicarbonate results in decreased expression of ABCG2 mRNA	29126803
D012980	Sodium Salicylate	ABCG2 protein binds to and results in increased transport of Sodium Salicylate	23652544
D012999	Soman	Soman results in decreased expression of ABCG2 mRNA	19281266
D053260	Soot	Soot results in increased expression of ABCG2 mRNA	26551751
D013311	Streptozocin	Streptozocin results in increased expression of ABCG2 mRNA	23319174
D013311	Streptozocin	Streptozocin results in increased expression of ABCG2 protein	23319174
D013427	Sulfapyridine	ABCG2 gene polymorphism affects the transport of Sulfapyridine	18167504
D013427	Sulfapyridine	ABCG2 protein results in increased transport of Sulfapyridine	18167504
D012460	Sulfasalazine	ABCG2 gene polymorphism affects the transport of Sulfasalazine	18167504\|1840856
D012460	Sulfasalazine	ABCG2 protein results in increased transport of Sulfasalazine	18167504\|1840856
D012460	Sulfasalazine	Dactinomycin inhibits the reaction [Sulfasalazine results in increased expression of ABCG2 mRNA]	20019844
D012460	Sulfasalazine	Sulfasalazine promotes the reaction [Cholesterol results in increased activity of ABCG2 protein]	27475308
D012460	Sulfasalazine	Sulfasalazine results in decreased methylation of ABCG2 promoter	20019844
D012460	Sulfasalazine	[Sulfasalazine results in decreased methylation of ABCG2 promoter] which results in increased expression of ABCG2 mRNA	20019844\|2001984
D012460	Sulfasalazine	Sulfasalazine results in increased activity of ABCG2 protein	27475308
C025462	sulindac sulfide	sulindac sulfide results in increased expression of ABCG2 mRNA	16184548
D013469	Sulpiride	ABCG2 protein results in increased transport of Sulpiride	28597291
D013469	Sulpiride	Elacridar inhibits the reaction [ABCG2 protein results in increased transport of Sulpiride]	28597291
C473478	sunitinib	sunitinib inhibits the reaction [ABCG2 results in decreased abundance of and results in decreased susceptibility to Doxorubicin]	19232821
C473478	sunitinib	sunitinib inhibits the reaction [ABCG2 results in decreased susceptibility to Topotecan]	19232821
C473478	sunitinib	sunitinib inhibits the reaction [ABCG2 results in increased export of Methotrexate]	19232821
C473478	sunitinib	sunitinib results in increased expression of ABCG2 mRNA	26797788
C473478	sunitinib	sunitinib results in increased expression of ABCG2 protein	26797788
C458508	T 0070907	rosiglitazone inhibits the reaction [T 0070907 results in decreased expression of ABCG2 mRNA]	27879033
C458508	T 0070907	T 0070907 results in decreased expression of ABCG2 mRNA	27879033
C458508	T 0070907	T 0070907 results in decreased expression of ABCG2 protein	27879033
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in decreased expression of ABCG2]	15695404
D013629	Tamoxifen	Tamoxifen metabolite results in increased expression of ABCG2 mRNA	29285606
D013629	Tamoxifen	ABCG2 affects the susceptibility to Tamoxifen	24169358
D013656	Taurocholic Acid	Taurocholic Acid results in increased expression of ABCG2 mRNA	27160211
C080625	taxane	taxane analog affects the activity of ABCG2 protein	15771464
C402729	tectochrysin	tectochrysin results in decreased activity of ABCG2 protein	15930306
D013739	Testosterone	ESR1 protein promotes the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D013739	Testosterone	[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA	17823853
D013739	Testosterone	[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein	17823853
D013739	Testosterone	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D013739	Testosterone	Flutamide inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
D013739	Testosterone	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 mRNA]	17823853
D013739	Testosterone	fulvestrant inhibits the reaction [[Estradiol co-treated with Testosterone] results in increased expression of ABCG2 protein]	17823853
D013739	Testosterone	Testosterone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate]	22581381
D013739	Testosterone	Testosterone results in decreased activity of ABCG2 protein	22581381
D013739	Testosterone	Testosterone results in increased expression of ABCG2 mRNA	21669218
C045037	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of ABCG2 mRNA	20189893
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased activity of ABCG2 protein	24014645
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA	23081912
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 protein	23081912
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]	24389113
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	24389113
D013749	Tetrachlorodibenzodioxin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]"	24389113
D013749	Tetrachlorodibenzodioxin	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]"	24389113
D013749	Tetrachlorodibenzodioxin	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]]	24389113
D013749	Tetrachlorodibenzodioxin	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein]	24389113
D013749	Tetrachlorodibenzodioxin	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	24389113
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased activity of ABCG2 protein	24389113
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA	24389113
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA]	23625689
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ABCG2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2	23081912
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 mRNA	15917307\|1683756
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 protein	15917307\|1707718
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of ABCG2 mRNA	21570461
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ABCG2 mRNA	28213091
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ABCG2 mRNA	21215274
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ABCG2 protein	21048045
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of ABCG2 protein	22472606
D013752	Tetracycline	Tetracycline results in decreased expression of ABCG2 mRNA	24489787
D013853	Thioacetamide	Thioacetamide results in increased expression of ABCG2 mRNA	23411599
D014028	Tobacco Smoke Pollution	AHR protein promotes the reaction [Tobacco Smoke Pollution results in increased expression of ABCG2 mRNA]	27450509
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	27450509
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of ABCG2 mRNA	27450509
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of ABCG2 protein	27450509
C426783	tolclofos-methyl	tolclofos-methyl inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]	27288731
D014050	Toluene	Toluene affects the expression of ABCG2 mRNA	18653662
D019772	Topotecan	ABCG2 protein affects the export of Topotecan	15695404
D019772	Topotecan	ABCG2 protein affects the transport of Topotecan	15875186\|1703290
D019772	Topotecan	ABCG2 protein results in decreased susceptibility to Topotecan	10606239\|1882954
D019772	Topotecan	ABCG2 protein results in increased export of Topotecan	10606239
D019772	Topotecan	ABCG2 protein results in increased susceptibility to Topotecan	16954373
D019772	Topotecan	ABCG2 protein results in increased transport of Topotecan	17032904
D019772	Topotecan	ABCG2 results in decreased susceptibility to Topotecan	19232821
D019772	Topotecan	[chrysin results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan	20457140
D019772	Topotecan	lapatinib inhibits the reaction [ABCG2 protein results in decreased susceptibility to Topotecan]	18829547
D019772	Topotecan	Protons promotes the reaction [ABCG2 protein results in increased transport of Topotecan]	17032904
D019772	Topotecan	sunitinib inhibits the reaction [ABCG2 results in decreased susceptibility to Topotecan]	19232821
D019772	Topotecan	Topotecan results in increased expression of ABCG2 protein	20457140
D019772	Topotecan	[tryptoquivaline results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan	20457140
D019772	Topotecan	ABCG2 protein affects the transport of Topotecan	15722455\|1703290
D019772	Topotecan	ABCG2 protein results in increased transport of Topotecan	17032904
D019772	Topotecan	Protons promotes the reaction [ABCG2 protein results in increased transport of Topotecan]	17032904
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in decreased expression of ABCG2 mRNA	25729387
D019772	Topotecan	Topotecan results in decreased expression of ABCG2 mRNA	25729387
D014212	Tretinoin	Am 580 promotes the reaction [Tretinoin results in increased expression of ABCG2 mRNA]	20562004
D014212	Tretinoin	CD 2608 promotes the reaction [Tretinoin results in increased expression of ABCG2 mRNA]	20562004
D014212	Tretinoin	Tretinoin results in increased expression of ABCG2 mRNA	20562004\|2193413
D014212	Tretinoin	Tretinoin results in increased expression of ABCG2 protein	20562004
D014221	Triamcinolone	"Triamcinolone inhibits the reaction [ABCG2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	15365089
D014223	Triamterene	ABCG2 protein affects the transport of Triamterene	18322075
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
C012589	trichostatin A	trichostatin A results in increased expression of ABCG2 mRNA	24935251\|2627250
C085104	triclabendazole sulfoxide	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C085104	triclabendazole sulfoxide	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C085104	triclabendazole sulfoxide	triclabendazole sulfoxide inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	24389113
C015559	trimellitic anhydride	trimellitic anhydride results in decreased expression of ABCG2 mRNA	19042947
C057693	troglitazone	troglitazone results in increased expression of ABCG2 mRNA	20804740
C010522	tryptoquivaline	"tryptoquivaline inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C010522	tryptoquivaline	"tryptoquivaline inhibits the reaction [ABCG2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"	23652544
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 gene mutant form results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of Acyclovir]	21859328
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein affects the uptake of Mitoxantrone]	15640379
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of and results in decreased susceptibility to Mitoxantrone]	18829547
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]	27450509
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of Methotrexate]	18829547
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of milbemycin]	19428349
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of Mitoxantrone]	19428349
C010522	tryptoquivaline	tryptoquivaline results in decreased activity of ABCG2 protein	19505989\|2045714
C010522	tryptoquivaline	[tryptoquivaline results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan	20457140
C010522	tryptoquivaline	"tryptoquivaline inhibits the reaction [ABCG2 protein affects the transport of 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine]"	20522663
C010522	tryptoquivaline	tryptoquivaline inhibits the reaction [Chlorpyrifos inhibits the reaction [ABCG2 protein results in increased secretion of bisbenzimide ethoxide trihydrochloride]]	27288731
C010522	tryptoquivaline	tryptoquivaline results in decreased activity of ABCG2 protein	15749994
C010522	tryptoquivaline	tryptoquivaline results in decreased activity of ABCG2 protein	21859328\|2365254
D014520	Urethane	Urethane results in decreased expression of ABCG2 mRNA	28818685
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCG2 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of ABCG2 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCG2 mRNA	23179753\|2438349
D014635	Valproic Acid	Valproic Acid results in increased expression of ABCG2 mRNA	27765674
D014638	Vanadates	Vanadates results in increased expression of ABCG2 mRNA	22714537
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of ABCG2 mRNA	25803276
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of ABCG2 protein	25803276
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of ABCG2 protein	18474546
C059141	verlukast	verlukast inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	12869632
C025643	vinclozolin	vinclozolin results in increased expression of ABCG2 mRNA	23034163
D014750	Vincristine	[Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine	21833476
D014750	Vincristine	[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCG2 mRNA	19944135
D014800	Vitallium	Vitallium analog results in decreased expression of ABCG2 mRNA	23825117
D024483	Vitamin K 3	Vitamin K 3 affects the expression of ABCG2 mRNA	20044591
C111237	vorinostat	ABCG2 protein affects the transport of vorinostat	23922875
D014859	Warfarin	ABCG2 SNP affects the susceptibility to Warfarin	25300812
C029659	zearalenol	zearalenol results in decreased expression of ABCG2 mRNA	22310176
C029659	zearalenol	zearalenol results in decreased expression of ABCG2 protein	22310176
C029659	zearalenol	zearalenol results in increased expression of ABCG2 mRNA	22310176
D015215	Zidovudine	Zidovudine results in increased expression of ABCG2 mRNA	24292225
D015215	Zidovudine	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]"	17437964
D015215	Zidovudine	"3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]"	19056916
D015215	Zidovudine	ABCG2 protein results in decreased export of Zidovudine	17437964
D015215	Zidovudine	ABCG2 protein results in increased export of Zidovudine	19056916
D015215	Zidovudine	Elacridar inhibits the reaction [ABCG2 protein results in decreased export of Zidovudine]	17437964
D015215	Zidovudine	Elacridar inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
D015215	Zidovudine	Nelfinavir inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
D015215	Zidovudine	pluronic block copolymer p85 inhibits the reaction [ABCG2 protein results in increased export of Zidovudine]	19056916
D015215	Zidovudine	Zidovudine results in decreased expression of ABCG2 mRNA	27765674
D015215	Zidovudine	Zidovudine results in increased expression of ABCG2 protein	28705594
C088658	zoledronic acid	zoledronic acid results in increased expression of ABCG2 mRNA	18225567
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]	23856525
C095179	zosuquidar trihydrochloride	zosuquidar trihydrochloride results in decreased activity of ABCG2 protein	23856525

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005215	transporter activity	-	TAS	9850061 9861027
GO:0005515	protein binding	-	IPI	18056989 19909340
GO:0005524	ATP binding	-	IEA	-
GO:0008559	xenobiotic transmembrane transporting ATPase activity	-	TAS	9861027
GO:0015232	heme transporter activity	-	TAS	-
GO:0015238	drug transmembrane transporter activity	-	IBA	21873635
GO:0017127	cholesterol transporter activity	CONTRIBUTES_TO	IBA	21873635
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	-	IBA	21873635
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	-	TAS	9850061
GO:0042802	identical protein binding	-	IPI	16870176 17098188 19506252 20399185
GO:0042803	protein homodimerization activity	-	IDA	16870176

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006855	drug transmembrane transport	-	IEA	-
GO:0006879	cellular iron ion homeostasis	-	TAS	-
GO:0015886	heme transport	-	IEA	-
GO:0033344	cholesterol efflux	-	IBA	21873635
GO:0042493	response to drug	-	TAS	9861027
GO:0042908	xenobiotic transport	-	IEA	-
GO:0046415	urate metabolic process	-	IMP	18834626 19503597 20053405
GO:0055085	transmembrane transport	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IDA	-
GO:0005886	plasma membrane	-	IBA	21873635
GO:0005886	plasma membrane	-	IDA	-
GO:0005886	plasma membrane	-	TAS	-
GO:0016324	apical plasma membrane	-	IBA	21873635
GO:0031966	mitochondrial membrane	-	IEA	-
GO:0043235	receptor complex	-	IBA	21873635

KEGG ID	KEGG Term
hsa02010	ABC transporters
hsa04976	Bile secretion

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	IEA
R-HSA-2161517	Abacavir transmembrane transport	IEA
R-HSA-2161522	Abacavir transport and metabolism	IEA
R-HSA-382551	Transport of small molecules	TAS
R-HSA-917937	Iron uptake and transport	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
23462698	Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver. (2013 May)	More VR	Drug Metab Dispos
23144836	Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population. (2012)	An Y	PLoS One
28111265	P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine. (2017 May)	Liao MZ	Pharmacol Res
15640379	Expression and function of ABCB1 and ABCG2 in human placental tissue. (2005 Apr)	Kolwankar D	Drug Metab Dispos
29307774	Liaison between heme metabolism and bioenergetics pathways-a multimodal elucidation for early diagnosis of oral cancer. (2018 Mar)	Sarkar R	Photodiagnosis Photodyn Ther
26109419	Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study. (2015)	Kopp TI	Scand J Gastroenterol
22751465	Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells. (2012 Aug 15)	Zhang M	Cancer Res
25288136	Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. (2015 May)	Cornelis MC	Mol Psychiatry
21678497	Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells. (2012 Jun)	To KK	Mol Carcinog
27974484	Buprenorphine, Norbuprenorphine, R-Methadone, and S-Methadone Upregulate BCRP/ABCG2 Expression by Activating Aryl Hydrocarbon Receptor in Human Placental Trophoblasts. (2017 Mar)	Neradugomma NK	Mol Pharmacol
23935829	Serum uric acid and non-alcoholic fatty liver disease in non-diabetic Chinese men. (2013)	Xie Y	PLoS One
21553932	Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on 4-anilinoquinazolines. (2011 Jun)	Scheffler M	Clin Pharmacokinet
26095139	Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR. (2015)	Toselli F	Xenobiotica
18819034	Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population. (2009)	Ostergaard M	Scand J Gastroenterol
19930591	Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study. (2009 Nov 21)	Andersen V	BMC Cancer
17505995	ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility, disease phenotype response to medical therapy or need for surgeryin Hungarian patients with inflammatory bowel diseases. (2007 Jun)	Fischer S	Scand J Gastroenterol
20570348	Toxicokinetics of the food-toxin IQ in human placental perfusion is not affected by ABCG2 or xenobiotic metabolism. (2010 Jul)	Immonen E	Placenta