Gene: CD44

960
CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1
CD44 molecule (Indian blood group)
protein-coding
11p13
Ensembl:ENSG00000026508 MIM:107269 Vega:OTTHUMG00000044388 UniprotKB:P16070
NG_008937.1
PubMed
ND|AD
39   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.497e-1 (AD)  2.417e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg23186333chr11:35161900CD441.180e-8Smoking28686328

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SERPINA30.869
GBP20.866
TIMP10.86
CHI3L20.858
S100A30.847
PIRT0.843
APOL40.841
C1R0.839
PDPN0.838
MMP140.832

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MARCH4-0.555
SLC7A4-0.55
EXTL1-0.546
KCNQ4-0.546
NEUROD6-0.546
SCRT1-0.538
F7-0.533
ABCC12-0.529
KIT-0.529
CHRM1-0.526

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB06550BivatuzumabBiotechDrugInvestigationalTarget
DB08818Hyaluronic acidSmall Molecule9004-61-9ApprovedTarget
ID Drug Name Action PubMed
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CD44 mRNA19933214
C1045642-(4-acetoxyphenyl)-2-chloro-N-methylethylamine2-(4-acetoxyphenyl)-2-chloro-N-methylethylamine results in decreased expression of CD44 protein19997594
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl affects the expression of CD44 mRNA"20638727
C5307733,5-diethoxycarbonyl-1,4-dihydrocollidine"3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of CD44 mRNA"27052460
C5307733,5-diethoxycarbonyl-1,4-dihydrocollidine"SULT2B1 protein promotes the reaction [3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of CD44 mRNA]"27052460
C0484603-deazaneplanocin[3-deazaneplanocin co-treated with trichostatin A] affects the expression of CD44 protein18538736
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of CD44 mRNA"18648102
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of CD44 mRNA"18289764
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CD44 mRNA19191707
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of CD44 mRNA20829426
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of CD44 mRNA25458485
D000082AcetaminophenAcetaminophen results in increased expression of CD44 mRNA27761495|2906747
D000082AcetaminophenCD44 gene polymorphism results in increased susceptibility to Acetaminophen19416960
D000082AcetaminophenAcetaminophen results in decreased expression of CD44 mRNA23358195
D000082AcetaminophenCD44 gene polymorphism results in increased susceptibility to Acetaminophen19416960
D000082AcetaminophenCD44 polymorphism results in increased susceptibility to Acetaminophen22940726
D000082Acetaminophen[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
D000171AcroleinAcrolein results in increased expression of CD44 mRNA18515264
D020106AcrylamideAcrylamide results in decreased expression of CD44 mRNA28959563
C096064acteinactein results in increased expression of CD44 mRNA19527300
D016604Aflatoxin B1Aflatoxin B1 affects the expression of CD44 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CD44 mRNA22100608|2715375
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of CD44 gene27153756
D000420AlbuterolAlbuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]18076728
D000420AlbuterolAlbuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]18076728
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of CD44 protein23936228
D013196DihydrotestosteroneSHBG affects the reaction [Dihydrotestosterone results in increased expression of CD44 protein]23936228
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CD44 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of CD44 mRNA"22863853
D000726Androgen Antagonists[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of CD44 mRNA24449571
D001151ArsenicArsenic results in decreased expression of CD44 mRNA16835338
C006632arsenic trioxidearsenic trioxide results in decreased expression of CD44 mRNA19804631
C006632arsenic trioxidearsenic trioxide results in decreased expression of CD44 mRNA alternative form22391160
C006632arsenic trioxidearsenic trioxide results in decreased expression of CD44 protein15553829
C006632arsenic trioxidearsenic trioxide results in decreased expression of CD44 protein alternative form22391160|2309847
C006632arsenic trioxide[Tretinoin co-treated with arsenic trioxide] results in increased expression of CD44 mRNA15894607
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CD44 mRNA"12839939|2416032
D017638Asbestos, Crocidolite"FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CD44 mRNA]"12839939
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CD44 mRNA"12839939
D017638Asbestos, Crocidolite"FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CD44 mRNA]"12839939
D001205Ascorbic Acid[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA23692848
D001205Ascorbic Acid[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein23692848
D001205Ascorbic AcidCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]23692848
D001205Ascorbic AcidCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]23692848
D001205Ascorbic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]"23692848
D001205Ascorbic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]"23692848
D001241AspirinAspirin results in decreased expression of CD44 protein alternative form16878161
D001241AspirinCTNNB1 affects the reaction [Aspirin results in decreased expression of CD44 protein alternative form]16878161
D001241AspirinAspirin results in decreased expression of CD44 mRNA12800193
C406592azaspiracidazaspiracid results in increased expression of CD44 mRNA28939011
D001414BacitracinBacitracin results in increased expression of CD44 mRNA18289764
C028559bathocuproine sulfonate[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]15477007
D001507BeclomethasoneAlbuterol promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]18076728
D001507BeclomethasoneAlbuterol promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]18076728
D001507BeclomethasoneBeclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]18076728
D001507BeclomethasoneBeclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]18076728
D001507BeclomethasoneFormoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]18076728
D001507BeclomethasoneFormoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]18076728
D001554BenzeneBenzene affects the expression of CD44 mRNA21147609
D001554BenzeneBenzene results in increased expression of CD44 mRNA15929907
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased splicing of CD44 mRNA20097212
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of CD44 mRNA26271895
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CD44 mRNA19770486
C020711beryllium sulfateberyllium sulfate results in increased expression of CD44 mRNA16314022
D004958EstradiolEstradiol affects the expression of CD44 mRNA25321415
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CD44 mRNA19619570
D004958EstradiolEstradiol results in increased expression of CD44 mRNA19167446|1961957
D004958EstradiolEstradiol results in increased expression of CD44 protein16912569
D004958Estradiol[Progesterone co-treated with Estradiol] results in increased expression of CD44 mRNA20226447
D001622BetaineBetaine results in decreased expression of CD44 mRNA26391144
C044887beta-methylcholinebeta-methylcholine affects the expression of CD44 mRNA21179406
C006780bisphenol Abisphenol A results in decreased expression of CD44 mRNA20678512|2257669
C006780bisphenol Abisphenol A results in increased expression of CD44 mRNA18007998|2654697
C006780bisphenol Abisphenol A affects the expression of CD44 mRNA25181051
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA25607892
C006780bisphenol Abisphenol A results in increased methylation of CD44 gene28505145
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of CD44 mRNA21601586
D002084Butylated Hydroxytoluene[Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of CD44 mRNA alternative form15390079
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA25607892
D020148Butyric AcidButyric Acid affects the expression of CD44 mRNA12800193
D002104CadmiumCadmium results in increased expression of CD44 mRNA22626610
D002104CadmiumCadmium results in increased expression of CD44 protein22626610
C459604candoxincandoxin results in increased expression of CD44 mRNA16309724
D002220CarbamazepineCarbamazepine affects the expression of CD44 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CD44 mRNA17484886|2733941
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG mRNA]18395288
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1A mRNA]18395288
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]18395288
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of LTB mRNA]18395288
D002251Carbon TetrachlorideCD44 protein affects the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]18395288
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of CD44 mRNA12734012
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CD44 protein12629582
D002330CarmustineCD44 mRNA affects the susceptibility to Carmustine16365179
D002713Chlorine[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA18636392
D002726Chlorogenic AcidChlorogenic Acid results in increased expression of CD44 mRNA20706672
D002746ChlorpromazineChlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD44 mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of CD44 mRNA28472532
D002939CiprofloxacinCiprofloxacin results in increased expression of CD44 protein26947806
C018021cobaltous chloridecobaltous chloride results in increased expression of CD44 mRNA19376846|2294125
C018021cobaltous chloridecobaltous chloride results in increased expression of CD44 protein16798617|2484233
C018021cobaltous chloride[EPAS1 protein results in increased susceptibility to cobaltous chloride] which results in increased expression of CD44 mRNA25805230
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of CD44 mRNA25805230
C018021cobaltous chloridetriptolide inhibits the reaction [cobaltous chloride results in increased expression of CD44 protein]24842335
D003042CocaineCocaine results in decreased expression of CD44 mRNA18000554
D003078ColchicineColchicine results in increased expression of CD44 mRNA20624997
D003300CopperCopper deficiency results in increased expression of CD44 mRNA26033743
D003300CopperCopper results in increased expression of CD44 mRNA22465980
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of CD44 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of CD44 mRNA19167446
C551994crizotinibcrizotinib results in decreased expression of CD44 mRNA22973962
C551994crizotinibcrizotinib results in decreased expression of CD44 protein22973962
D003471CuprizoneCuprizone results in increased expression of CD44 mRNA27523638
D003474CurcuminCurcumin results in increased expression of CD44 mRNA15713895
D003513CycloheximideCycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]9929743
D016572CyclosporineCyclosporine results in increased expression of CD44 mRNA20106945
D016572CyclosporineCyclosporine results in increased expression of CD44 mRNA19770486
D016572CyclosporineCyclosporine results in increased expression of CD44 mRNA21865292
D003561CytarabineCytarabine results in decreased expression of CD44 mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of CD44 mRNA23640034
C014347decitabinedecitabine affects the expression of CD44 mRNA23300844
C014347decitabinedecitabine results in increased expression of CD44 mRNA27915011
C107676deguelindeguelin results in decreased expression of CD44 mRNA26884827
C107676deguelindeguelin results in decreased expression of CD44 protein26884827
D003703DemecolcineDemecolcine results in increased expression of CD44 mRNA23649840
D016264Dextran Sulfate[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of CD44 mRNA26271895
D016190CarboplatinCarboplatin results in decreased expression of CD44 mRNA18172885
D003976DiazinonDiazinon results in increased methylation of CD44 gene22964155
D003993Dibutyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CD44 mRNA21266533
D002945CisplatinCD44 gene mutant form results in decreased susceptibility to Cisplatin21471434
D002945CisplatinCD44 protein results in decreased susceptibility to Cisplatin21124918
D002945CisplatinCisplatin affects the expression of CD44 mRNA23300844
D002945CisplatinCisplatin results in increased expression of CD44 mRNA27392435
D002945CisplatinCisplatin results in increased expression of CD44 protein21618587
D002945CisplatinCisplatin results in increased expression of CD44 mRNA21151649
D002945CisplatinCisplatin results in increased expression of CD44 mRNA18289764
D003633Dichlorodiphenyl Dichloroethylene[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D004008DiclofenacDiclofenac results in increased expression of CD44 mRNA26934552
D019259Lamivudine[Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA15784690
D004041Dietary FatsDietary Fats results in increased expression of CD44 mRNA18042831
D019422Dietary SucroseDietary Sucrose results in increased expression of CD44 mRNA26033743
D004051Diethylhexyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CD44 mRNA21527772
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CD44 protein27058323
D004052Diethylnitrosamineepigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]27058323
D004052Diethylnitrosaminetheaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]27058323
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CD44 mRNA19638242
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CD44 mRNA26865669
D002117CalcitriolCalcitriol results in decreased expression of CD4416051482
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of CD44 mRNA20886546
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CD44 protein14643895
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of CD44 mRNA28939011
D004237DiuronDiuron results in increased expression of CD44 mRNA21551480
D004317DoxorubicinDoxorubicin results in increased expression of CD44 mRNA16705698
D004317Doxorubicin[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin19047049
D004317Doxorubicin[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D004317Doxorubicin[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D004317Doxorubicin[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin19047049
D004317Doxorubicin[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D004317Doxorubicin[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D004317Doxorubicinresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]19047049
D004317Doxorubicinresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]19047049
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of CD44 mRNA"23262642
D004391DustDust results in increased expression of CD44 mRNA17805423
C118739entinostatentinostat results in increased expression of CD44 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA25607892
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CD44 protein23301498
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]27058323
C109476epoxiconazole[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CD44 mRNA12655037
D008656MestranolMestranol results in increased expression of CD44 mRNA26865669
D017308EtodolacEtodolac results in decreased expression of CD44 protein16046235
D005047EtoposideCD44 protein affects the susceptibility to Etoposide15215046
D005047Etoposide[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide19047049
D005047Etoposide[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D005047Etoposide[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D005047Etoposide[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide19047049
D005047Etoposide[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D005047Etoposide[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D005047Etoposideresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]19047049
D005047Etoposideresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]19047049
C020326ferric nitrilotriacetateferric nitrilotriacetate results in increased expression of CD44 mRNA18055543
C020326ferric nitrilotriacetateferric nitrilotriacetate results in increased expression of CD44 protein18055543
C020748ferrous sulfate[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA23692848
C020748ferrous sulfate[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein23692848
C020748ferrous sulfateCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]23692848
C020748ferrous sulfateCAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]23692848
C020748ferrous sulfate"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]"23692848
C020748ferrous sulfate"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]"23692848
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CD44 mRNA17187413|2258468
D005472Fluorouracil[gimeracil co-treated with Fluorouracil] results in decreased expression of CD4412364819
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD44 mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of CD44 mRNA20655997
D005557FormaldehydeFormaldehyde results in increased expression of CD44 mRNA23649840
D000068759Formoterol FumarateFormoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [FGF2 protein results in decreased expression of CD44 protein]]18076728
D000068759Formoterol FumarateFormoterol Fumarate promotes the reaction [Beclomethasone inhibits the reaction [IL4 protein results in decreased expression of CD44 protein]]18076728
C070081fulvestrantfulvestrant results in decreased expression of CD44 mRNA26865669
C070081fulvestrantfulvestrant inhibits the reaction [Genistein results in increased expression of CD44 mRNA]22553218
C039281furanfuran results in increased expression of CD44 mRNA27387713
D019833GenisteinGenistein results in decreased expression of CD44 mRNA16705744
D019833GenisteinGenistein results in increased expression of CD44 mRNA20706672|2686566
D019833Genisteinfulvestrant inhibits the reaction [Genistein results in increased expression of CD44 mRNA]22553218
D019833GenisteinGenistein results in increased expression of CD44 mRNA22553218
D005839GentamicinsGentamicins results in increased expression of CD44 mRNA22061828
D005839GentamicinsGentamicins results in increased expression of CD44 protein11231351
C104201gimeracil[gimeracil co-treated with Fluorouracil] results in decreased expression of CD4412364819
D005947GlucoseGlucose results in increased expression of CD44 mRNA17178593
C004312glycidolglycidol results in decreased expression of CD44 mRNA24915197
C010974glyphosateglyphosate results in increased expression of CD44 mRNA28711546
C010176halofuginonehalofuginone results in increased expression of CD44 mRNA17180598
C014026hexamethylene bisacetamidehexamethylene bisacetamide results in decreased expression of CD44 mRNA17349212
D006589HexestrolHexestrol results in increased expression of CD44 mRNA26865669
D006820Hyaluronic AcidHyaluronic Acid analog binds to and results in increased activity of CD44 protein12402308
D006820Hyaluronic Acid[Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU mRNA12402308
D006820Hyaluronic Acid[Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAU protein12402308
D006820Hyaluronic Acid[Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR mRNA12402308
D006820Hyaluronic Acid[Hyaluronic Acid analog binds to and results in increased activity of CD44 protein] which results in increased expression of PLAUR protein12402308
D006820Hyaluronic AcidHyaluronic Acid binds to CD44 protein19047049
D006820Hyaluronic Acid[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein19047049
D006820Hyaluronic Acid[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA19047049
D006820Hyaluronic Acid[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acid[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]19047049
D006820Hyaluronic Acidresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]19047049
D006820Hyaluronic AcidHyaluronic Acid analog affects the localization of [MAP3K1 protein binds to CD44 protein]20159036
D006820Hyaluronic AcidHyaluronic Acid analog promotes the reaction [MAP3K1 protein binds to CD44 protein]20159036
D006820Hyaluronic AcidHyaluronic Acid metabolite results in increased expression of CD44 mRNA23692848
D006820Hyaluronic AcidHyaluronic Acid metabolite results in increased expression of CD44 protein23692848
D006820Hyaluronic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 mRNA]"23692848
D006820Hyaluronic Acid"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 protein]"23692848
D006820Hyaluronic AcidTetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]9929743
D006820Hyaluronic AcidVerapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]9929743
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CD44 mRNA20044591
D006861Hydrogen Peroxide[Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD44 mRNA24489904
C475919hydroxytamoxifenhydroxytamoxifen results in increased expression of CD44 mRNA16849584
D006923HymecromoneHymecromone results in decreased expression of CD44 mRNA23139787
D007213IndomethacinIndomethacin results in increased expression of CD44 mRNA16771604
D015759Ionomycin[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]15477007
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA15477007
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CD44 mRNA25613284
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CD44 mRNA25961927
C006552kaempferolkaempferol inhibits the reaction [IL32 protein results in increased expression of CD44 protein]28711657
C006552kaempferolkaempferol inhibits the reaction [APOE affects the expression of CD44 mRNA]22005275
C006552kaempferolkaempferol inhibits the reaction [APOE affects the expression of CD44 protein]22005275
D048628KetolidesKetolides analog results in increased expression of CD44 mRNA24967691
C490728lapatinib[lapatinib results in decreased susceptibility to lapatinib] which results in increased expression of CD44 protein26643609
C052901lemongrass oillemongrass oil affects the expression of CD44 mRNA25976427
C052901lemongrass oillemongrass oil results in decreased expression of CD44 mRNA25660481
D008044Linuron[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CD44 mRNA27339419
D018021Lithium ChlorideLithium Chloride results in increased expression of CD44 mRNA23527032
D008148LovastatinLovastatin results in decreased expression of CD44 mRNA21199873
D008148LovastatinLovastatin results in decreased expression of CD44 protein21199873
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CD44 mRNA26378955
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CD44 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CD44 mRNA26378955
C011907melaminemelamine results in increased expression of CD4423052191
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
D008701MethapyrileneMethapyrilene results in increased expression of CD44 protein28935588
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CD44 mRNA20938992
D008731MethoxychlorMethoxychlor affects the expression of CD44 mRNA20829426
D008748Methylcholanthrene[Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of CD44 mRNA alternative form15390079
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CD44 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CD44 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CD44 mRNA23649840
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CD44 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CD44 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CD44 mRNA]"20230807
C008493methylselenic acidmethylselenic acid results in decreased expression of CD44 mRNA12517777
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CD44 protein]21199873
D015735MifepristoneMifepristone results in increased expression of CD44 mRNA19439560
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 mRNA]"23692848
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Hyaluronic Acid metabolite results in increased expression of CD44 protein]"23692848
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of CD44 mRNA25145660
C500085muraglitazarmuraglitazar results in decreased expression of CD44 mRNA21515302
D009151Mustard GasMustard Gas results in increased expression of CD44 mRNA15674843|1895507
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of CD44 mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CD44 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CD44 mRNA"25554681
C000621033napabucasinnapabucasin results in decreased expression of CD44 mRNA25605917
D009532NickelNickel affects the expression of CD44 mRNA14575637
D009532NickelNickel results in increased expression of CD44 mRNA24768652|2558310
D009532Nickeltrichostatin A inhibits the reaction [Nickel affects the expression of CD44 mRNA]14575637
C022838nickel chloridenickel chloride results in increased expression of CD44 protein26962057
D009538Nicotine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CD44 mRNA"20230807
D009538Nicotine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CD44 mRNA]"20230807
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of CD44 mRNA17616710
C025589ochratoxin Aochratoxin A results in increased expression of CD44 mRNA23358140
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA25607892
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA25607892
D019319Okadaic AcidOkadaic Acid results in increased expression of CD44 mRNA28939011
C507134ON 01910ON 01910 results in increased expression of CD44 mRNA22351695
C485800osajinosajin results in increased expression of CD44 mRNA20706672
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of CD44 mRNA17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of CD44 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of CD44 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of CD44 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of CD44 mRNA]17655762
D010100OxygenOxygen deficiency results in decreased expression of CD44 protein25351418
D010100Oxygenvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of CD44 protein]26305601
D010126OzoneOzone results in increased expression of CD44 mRNA12763052
D010126Ozone[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA18636392
D000073878Palm OilPalm Oil results in increased expression of CD44 mRNA18042831
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of CD44 mRNA26272509
D010269ParaquatParaquat results in decreased expression of CD44 mRNA18198484
D052638Particulate Matteroxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of CD44 mRNA]17655762
D052638Particulate MatterParticulate Matter affects the expression of CD44 mRNA17655762
D052638Particulate MatterParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of CD44 mRNA]17655762
D052638Particulate MatterParticulate Matter results in increased expression of CD44 mRNA28846189
D052638Particulate MatterParticulate Matter results in increased expression of CD44 protein28846189
D052638Particulate MatterParticulate Matter results in increased expression of CD44 mRNA21708214
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of CD44 mRNA26705709
D010634PhenobarbitalPhenobarbital affects the expression of CD44 mRNA19159669
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of CD44 mRNA]19482888
D010634PhenobarbitalPhenobarbital affects the expression of CD44 mRNA23091169
D010634PhenobarbitalPhenobarbital results in increased expression of CD44 mRNA19482888
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CD44 mRNA26272509
D010862PilocarpinePilocarpine results in increased expression of CD44 protein15191797
C006253pirinixic acidpirinixic acid results in decreased expression of CD44 mRNA17426115|2081375
D010894PiroxicamPiroxicam results in increased expression of CD44 mRNA21858171
D010936Plant ExtractsHOTAIR mutant form inhibits the reaction [Plant Extracts analog results in increased expression of CD44 mRNA]25447409
D010936Plant ExtractsPlant Extracts analog results in increased expression of CD44 mRNA25447409
D010936Plant ExtractsPlant Extracts results in increased expression of CD44 mRNA23262642
C474837pomiferinpomiferin results in increased expression of CD44 mRNA20706672
C045362prochloraz[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
C035988procymidone[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D011374ProgesteroneProgesterone results in decreased expression of CD44 mRNA23012394
D011374Progesterone[Progesterone co-treated with Estradiol] results in increased expression of CD44 mRNA20226447
D011374ProgesteroneProgesterone results in decreased expression of CD44 mRNA18692832
D011374ProgesteroneProgesterone results in increased expression of CD44 mRNA22238285
D011374ProgesteroneProgesterone results in decreased expression of CD44 mRNA20726854
D011374ProgesteroneProgesterone results in increased expression of CD44 mRNA21770760
C045950propiconazolepropiconazole results in increased expression of CD44 mRNA21278054
D011429PropolisPropolis results in increased expression of CD44 mRNA20706672
D011441PropylthiouracilPropylthiouracil results in increased expression of CD44 mRNA24780913
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of CD44 protein8635280
C020972pyrrolidine dithiocarbamic acid[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]15477007
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of CD44 mRNA26865669
D017382Reactive Oxygen Species[Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD44 mRNA24489904
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in decreased expression of CD44 protein21833471
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of CD44 mRNA19167446
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Doxorubicin]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 mRNA]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 mRNA]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Doxorubicin]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 mRNA]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 mRNA]19047049
C059514resveratrolresveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein]19047049
C059514resveratrolresveratrol results in decreased expression of CD44 protein22692956
C059514resveratrolresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD44 protein]20715097
C059514resveratrolresveratrol results in decreased expression of CD44 protein25505154
C089730rosiglitazonerosiglitazone affects the expression of CD44 mRNA21515302
D012643SeleniumSelenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]18196609
D012643SeleniumSelenium results in increased expression of CD44 mRNA18196609
D012643SeleniumSelenium results in increased expression of CD44 protein18196609
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CD44 mRNA"21514415
C112356seryl-leucyl-isoleucyl-glycyl--arginyl-leucinamideseryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein]11717450
D012822Silicon DioxideSilicon Dioxide results in increased expression of CD44 mRNA19073995|2322117
D012822Silicon DioxideSilicon Dioxide results in increased expression of CD44 mRNA21602193
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CD44 protein]21199873
D019821SimvastatinSimvastatin promotes the reaction [TP53 protein binds to CD44 promoter]21199873
D019821SimvastatinSimvastatin results in decreased expression of CD44 mRNA21199873
D019821SimvastatinSimvastatin results in decreased expression of CD44 protein21199873
D012906SmokeHOTAIR mutant form inhibits the reaction [Smoke analog results in increased expression of CD44 mRNA]25447409
D012906SmokeSmoke analog results in increased expression of CD44 mRNA25447409|2552692
D012906SmokeSmoke results in increased expression of CD44 mRNA21095227
C017947sodium arsenitesodium arsenite affects the methylation of CD44 gene28589171
C017947sodium arsenitesodium arsenite results in decreased expression of CD44 mRNA25879800
C017947sodium arsenitesodium arsenite results in increased expression of CD44 protein23549458
C017947sodium arsenitesodium arsenite results in increased stability of CD44 mRNA25493608
C016104sodium bichromatesodium bichromate results in increased expression of CD44 mRNA22561333
D012999SomanSoman results in increased expression of CD44 mRNA19281266
D053260SootSoot results in increased expression of CD44 mRNA22461453
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CD44 mRNA26378955
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CD44 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CD44 mRNA26378955
D013605T-2 ToxinSelenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]18196609
D013605T-2 ToxinT-2 Toxin results in decreased expression of CD44 mRNA18196609
D013605T-2 ToxinT-2 Toxin results in decreased expression of CD44 protein18196609
D016559TacrolimusTacrolimus results in increased expression of CD44 mRNA21865292
C061133tamibarotenetamibarotene affects the expression of CD44 mRNA15498508
C061133tamibarotenetamibarotene results in decreased expression of CD44 mRNA17229644
D013629TamoxifenTamoxifen affects the expression of CD44 mRNA14699072
C047246temozolomideCD44 mRNA affects the susceptibility to temozolomide16365179
C501413tesaglitazartesaglitazar results in decreased expression of CD44 mRNA21515302
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CD44 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD44 mRNA19619570|2010694
D013749Tetrachlorodibenzodioxinresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD44 protein]20715097
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CD44 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which affects the expression of CD44 mRNA15135321
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which affects the expression of CD44 protein15135321
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CD44 mRNA alternative form15135321
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CD44 protein alternative form15135321
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD44 mRNA15800033|1869160
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD44 protein14718643|1597263
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CD44 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD44 mRNA22808131
D013755Tetradecanoylphorbol Acetate[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]15477007
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA15477007
D013755Tetradecanoylphorbol AcetateChlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
D013755Tetradecanoylphorbol AcetateCycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]9929743
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]9929743
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein9929743
D013755Tetradecanoylphorbol AcetateTrifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
D013755Tetradecanoylphorbol AcetateVerapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]9929743
D013755Tetradecanoylphorbol AcetateVerapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]9929743
D013755Tetradecanoylphorbol AcetateW 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CD44 mRNA25613284
C056068theaflavintheaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]27058323
D013853ThioacetamideThioacetamide results in increased expression of CD44 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of CD44 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CD44 mRNA27480279
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased methylation of CD44 gene26756918
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CD44 mRNA20133372
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CD44 mRNA28111298
D014118Toxins, Biological"Toxins, Biological affects the expression of CD44 mRNA"19682533
D014212Tretinoin[Tretinoin co-treated with arsenic trioxide] results in increased expression of CD44 mRNA15894607
D014212TretinoinTretinoin results in decreased expression of CD44 mRNA15498508|1734921
D014212TretinoinTretinoin results in decreased expression of CD44 mRNA alternative form22391160
D014212TretinoinTretinoin results in increased expression of CD44 mRNA15894607|2193413
D014212TretinoinTretinoin results in decreased expression of CD44 mRNA22498432
D014212TretinoinTretinoin results in increased expression of CD44 protein16724877
C012589trichostatin A[3-deazaneplanocin co-treated with trichostatin A] affects the expression of CD44 protein18538736
C012589trichostatin Atrichostatin A inhibits the reaction [Nickel affects the expression of CD44 mRNA]14575637
C012589trichostatin Atrichostatin A results in increased expression of CD44 mRNA24935251
C012589trichostatin Atrichostatin A results in decreased expression of CD44 mRNA15901671
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
C046488trimethyltintrimethyltin results in increased expression of CD44 mRNA24002884
D014302Trinitrobenzenesulfonic Acidseryl-leucyl-isoleucyl-glycyl--arginyl-leucinamide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD44 protein]11717450
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CD44 protein11717450
C001899triptolidetriptolide inhibits the reaction [cobaltous chloride results in increased expression of CD44 protein]24842335
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD44 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased methylation of CD44 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of CD44 mRNA23179753|2352703
D014635Valproic AcidValproic Acid results in decreased expression of CD44 mRNA15901671
C066075vanadium pentoxidevanadium pentoxide affects the expression of CD44 mRNA17459161
C066075vanadium pentoxidevanadium pentoxide affects the expression of CD44 mRNA26210822
D014640VancomycinVancomycin results in increased expression of CD44 mRNA18289764
D001335Vehicle Emissionsoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of CD44 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions affects the expression of CD44 mRNA17655762
D001335Vehicle EmissionsVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of CD44 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of CD44 gene25560391
D014700VerapamilVerapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]9929743
D014700VerapamilVerapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]9929743
D014747VinblastineVinblastine results in increased expression of CD44 mRNA20624997
C025643vinclozolin[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA25607892
D014750VincristineVincristine results in increased expression of CD44 mRNA23649840
C029297vinylidene chloridevinylidene chloride results in increased expression of CD44 mRNA26682919
D014801Vitamin AVitamin A results in increased expression of CD44 protein16724877
D014810Vitamin EVitamin E results in decreased expression of CD44 mRNA19244175
D024483Vitamin K 3Vitamin K 3 affects the expression of CD44 mRNA20829426
C111237vorinostatvorinostat inhibits the reaction [Oxygen deficiency results in increased expression of CD44 protein]26305601
C017967W 7W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]9929743
D015215Zidovudine[Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA15784690
C088658zoledronic acidzoledronic acid results in increased expression of CD44 mRNA24714768
D015054ZymosanZymosan results in increased expression of CD44 mRNA11361220
D015054ZymosanZymosan results in increased expression of CD44 mRNA alternative form11361220

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004888transmembrane signaling receptor activity-IBA21873635  
GO:0004896cytokine receptor activityCONTRIBUTES_TOIBA21873635  
GO:0004896cytokine receptor activitycontributes_toIDA17045821  
GO:0005515protein binding-IPI11207560  20146103  20549562  20962267  21397861  23855374  
29190904  
GO:0005518collagen binding-NAS2471973  
GO:0005540hyaluronic acid binding-IBA21873635  
GO:0005540hyaluronic acid binding-IDA17170110  17324121  
GO:0005540hyaluronic acid binding-NAS1991450  
GO ID GO Term Qualifier Evidence PubMed
GO:0006954inflammatory response-IBA21873635  
GO:0007155cell adhesion-IBA21873635  
GO:0007160cell-matrix adhesion-NAS1922057  
GO:0007166cell surface receptor signaling pathway-IBA21873635  
GO:0022617extracellular matrix disassembly-TAS-  
GO:0030198extracellular matrix organization-TAS-  
GO:0030214hyaluronan catabolic process-IDA17170110  
GO:0030214hyaluronan catabolic process-TAS-  
GO:0033138positive regulation of peptidyl-serine phosphorylation-IDA17045821  
GO:0034116positive regulation of heterotypic cell-cell adhesion-IMP15100360  
GO:0043066negative regulation of apoptotic process-IMP19047049  
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-IMP19047049  
GO:0043312neutrophil degranulation-TAS-  
GO:0043518negative regulation of DNA damage response, signal transduction by p53 class mediator-IDA17045821  
GO:0044319wound healing, spreading of cells-IMP20962267  
GO:0044344cellular response to fibroblast growth factor stimulus-IDA19577615  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-IDA17045821  
GO:0050900leukocyte migration-TAS-  
GO:0051216cartilage development-IEP11944887  
GO:0060333interferon-gamma-mediated signaling pathway-TAS-  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IBA21873635  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IDA17045821  
GO:0070487monocyte aggregation-IMP15100360  
GO:0098609cell-cell adhesion-NAS1922057  
GO:1900625positive regulation of monocyte aggregation-IMP20522558  
GO:1902166negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-IDA17045821  
GO:2000392regulation of lamellipodium morphogenesis-IMP20962267  
GO ID GO Term Qualifier Evidence PubMed
GO:0005794Golgi apparatus-IDA-  
GO:0005829cytosol-IDA-  
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-IDA20962267  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-NAS1991450  
GO:0005902microvillus-ISS-  
GO:0005925focal adhesion-HDA21423176  
GO:0009986cell surface-IDA16809613  17170110  
GO:0016323basolateral plasma membrane-IBA21873635  
GO:0016324apical plasma membrane-IDA20962267  
GO:0030667secretory granule membrane-TAS-  
GO:0031258lamellipodium membrane-IDA20962267  
GO:0035692macrophage migration inhibitory factor receptor complex-IBA21873635  
GO:0035692macrophage migration inhibitory factor receptor complex-IDA17045821  
GO:0042995cell projection-IDA20962267  
GO:0070062extracellular exosome-HDA19199708  20458337  23533145  
KEGG ID KEGG Term
hsa04512ECM-receptor interaction
hsa04640Hematopoietic cell lineage
hsa05131Shigellosis
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1430728MetabolismTAS
R-HSA-1474228Degradation of the extracellular matrixTAS
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1630316Glycosaminoglycan metabolismTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-202733Cell surface interactions at the vascular wallTAS
R-HSA-2142845Hyaluronan metabolismTAS
R-HSA-216083Integrin cell surface interactionsTAS
R-HSA-2160916Hyaluronan uptake and degradationTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-71387Metabolism of carbohydratesTAS
R-HSA-877300Interferon gamma signalingTAS
R-HSA-913531Interferon SignalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21514878Significance of site-specific prognosis of cancer stem cell marker CD44 in head and neck squamous-cell carcinoma. (2011 Jun)Kokko LLOral Oncol
10980691Thyroid-associated eye disease. (2000 Jun)Heufelder AEStrabismus
20529829Targeting novel antigens in the arterial wall in thromboangiitis obliterans. (2010 Jan 1)Guzel EFolia Histochem Cytobiol
11704996Pathogenesis of ophthalmopathy in autoimmune thyroid disease. (2000 Jan)Heufelder AERev Endocr Metab Disord
26025766A model for predicting clinical outcome in patients with human papillomavirus-positive tonsillar and base of tongue cancer. (2015 Aug)Tertipis NEur J Cancer
29416638Nicotine-enhanced stemness and epithelial-mesenchymal transition of human umbilical cord mesenchymal stem cells promote tumor formation and growth in nude mice. (2018 Jan 2)Li TOncotarget
18570728[Expression and significance of CD44(+)ESA(+)CD24(-/low), stem cell markers for breast cancer, in non-small-cell lung carcinoma]. (2008 Jun)Lu ZQAi Zheng
20020508Human cleft lip and palate fibroblasts and normal nicotine-treated fibroblasts show altered in vitro expressions of genes related to molecular signaling pathways and extracellular matrix metabolism. (2010 Mar)Baroni TJ Cell Physiol
29540668Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway. (2018 Mar 13)Qian WOncogenesis
27442811Combined CD44, c-MET, and EGFR expression in p16-positive and p16-negative head and neck squamous cell carcinomas. (2017 Mar)Baschnagel AMJ Oral Pathol Med
23974104High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors. (2013 Sep 15)Robinson TJCell Cycle
24178866CD44+/CD133+ immunophenotype and matrix metalloproteinase-9: Influence on prognosis in early-stage oral squamous cell carcinoma. (2014 Dec)Oliveira LRHead Neck
21073537Cancer stem cell immunophenotypes in oral squamous cell carcinoma. (2011 Feb)Oliveira LRJ Oral Pathol Med
27100677Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. (2016)Sato KPLoS One
9056747Significant elevation of tumour-associated isoforms of soluble CD44 in serum of normal individuals caused by cigarette smoking. (1997 Feb)Kittl EMEur J Clin Chem Clin Biochem
29029509Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations. (2017 Sep 12)Svobodova MOncotarget
24699672CD44 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan. (2014)Chou YEPLoS One
17595754Associations between ten biological tumor markers in squamous cell cervical cancer and serum estradiol, serum progesterone and smoking. (2007 May-Jun)Lindstrom AKAnticancer Res
27628948The Emerging Role of the Hippo Pathway in Lung Cancers: Clinical Implications. (2017 Nov 30)Teoh SLCurr Drug Targets
25439508Cyclic tensile strain on vocal fold fibroblasts inhibits cigarette smoke-induced inflammation: implications for Reinke edema. (2015 Jan)Zhang HJ Voice
24971320CD44 gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic features. (2014)Chou YEBiomed Res Int
23876628Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer. (2013 Sep)Sinha NOral Oncol
11668200Low serum levels of CD44, CD44v6, and neopterin indicate immune dysfunction in chronic pancreatitis. (2001 Nov)Schlosser WPancreas
11097229Plasma concentrations of reputed tumor-associated soluble CD44 isoforms (v5 and v6) in smokers are dose related and decline on smoking cessation. (2000 Nov)Scott DACancer Epidemiol Biomarkers Prev
23148928An investigation of the resolution of inflammation (catabasis) in COPD. (2012 Nov 13)Noguera ARespir Res
22699785Salivary markers and risk factor data: a multivariate modeling approach for head and neck squamous cell carcinoma detection. (2011)Pereira LHCancer Biomark
25624630Comparative evaluation of salivary soluble CD44 levels in periodontal health and disease. (2014 Nov-Dec)Kaur SJ Indian Soc Periodontol
28959653p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C. (2017)Ganguly SToxicol Rep
12849800Blood leukocyte subsets are modulated in patients with endometriosis. (2003 Jul)Gagne DFertil Steril
26999446Aggravation of Allergic Airway Inflammation by Cigarette Smoke in Mice Is CD44-Dependent. (2016)Kumar SPLoS One
28008391Evaluation of the Correlation between CD44, Tumor Prognosis and the 5-Year Survival Rate in Patients with Oral Tongue SCC. (2016 Nov)Kaboodkhani RIran J Otorhinolaryngol
27222041A proteomic signature of ovarian cancer tumor fluid identified by highthroughput and verified by targeted proteomics. (2016 Aug 11)Poersch AJ Proteomics
11593897[Interactions of fibroblasts, adipocytes and immunocompeent cells in the pathogenesis of endocrine ophthalmopathy]. (2001)Heufelder AEActa Med Austriaca
17513004Elevated circulating level of osteopontin is associated with advanced disease state of non-small cell lung cancer. (2007 Sep)Chang YSLung Cancer
24676623Human papillomavirus and oropharyngeal cancer, the epidemics, and significance of additional clinical biomarkers for prediction of response to therapy (Review). (2014 Jun)Dalianis TInt J Oncol
17630319Smoking alters alveolar macrophage recognition and phagocytic ability: implications in chronic obstructive pulmonary disease. (2007 Dec)Hodge SAm J Respir Cell Mol Biol
21487404Disulfiram modulated ROS-MAPK and NFkappaB pathways and targeted breast cancer cells with cancer stem cell-like properties. (2011 May 10)Yip NCBr J Cancer
22901197Elevated circulating CD19+ lymphocytes predict survival advantage in patients with gastric cancer. (2012)Yu QMAsian Pac J Cancer Prev
20429650Salivary-soluble CD44 levels in smokers and non-smokers with chronic periodontitis: a pilot study. (2010 May)Ghallab NJ Periodontol