Gene: CEP104

9731
CFAP256|GlyBP|JBTS25|KIAA0562|ROC22
centrosomal protein 104
protein-coding
1p36.32
Ensembl:ENSG00000116198 MIM:616690 Vega:OTTHUMG00000003507 UniprotKB:O60308
NG_046726.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.499e-1 (AD)  6.175e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7545274chr1:3827697 (GRCh38.p7)C>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
POGK0.891
BAZ1B0.871
DST0.854
TEX20.844
LIMCH10.843
TRMT10B0.826
CASC30.824
YTHDC10.824
COBL0.819
DENND5A0.817

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.576
OR4F5-0.524
OR4F16-0.281
RSPO1-0.247
SPRR2B-0.231
MTRNR2L10-0.221
C17orf112-0.218
TTLL10-AS1-0.214
MTRNR2L3-0.213
CACNG1-0.211

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of CEP104 mRNA26690555
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of CEP104 mRNA24449571
D001151ArsenicArsenic affects the methylation of CEP104 gene25304211
C006780bisphenol Abisphenol A results in decreased expression of CEP104 mRNA25181051
D019327Copper SulfateCopper Sulfate results in decreased expression of CEP104 mRNA19549813
D005038EthylnitrosoureaEthylnitrosourea results in increased mutagenesis of CEP104 gene27776689
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of CEP104 mRNA26846883
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of CEP104 mRNA24796395
C410337K 7174K 7174 results in increased expression of CEP104 mRNA24086573
D008694MethamphetamineMethamphetamine affects the expression of CEP104 mRNA19564919
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA19564919
D008727MethotrexateMethotrexate results in increased expression of CEP104 mRNA24449571
D011374ProgesteroneProgesterone results in increased expression of CEP104 mRNA23012394
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA19564919
C534628SCH 23390SCH 23390 affects the expression of CEP104 mRNA19564919
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of CEP104 mRNA"26680231
C004648testosterone enanthatetestosterone enanthate affects the expression of CEP104 mRNA17440010
C057693troglitazonetroglitazone results in decreased expression of CEP104 mRNA28973697
D014520UrethaneUrethane results in increased expression of CEP104 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of CEP104 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of CEP104 mRNA23179753
D014635Valproic AcidValproic Acid results in increased expression of CEP104 mRNA24935251
D014635Valproic AcidValproic Acid results in increased methylation of CEP104 gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of CEP104 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI26420826  
GO:0016594glycine binding-IEA-  
GO:0016595glutamate binding-IEA-  
GO:0016596thienylcyclohexylpiperidine binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0000922spindle pole-IEA-  
GO:0005814centriole-IDA21399614  
GO:0005929cilium-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal