Gene: CD151

977
GP27|MER2|PETA-3|RAPH|SFA1|TSPAN24
CD151 molecule (Raph blood group)
protein-coding
11p15.5
Ensembl:ENSG00000177697 MIM:602243 Vega:OTTHUMG00000133311 UniprotKB:P48509
NG_007478.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.594e-1 (AD)  3.427e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EHD20.844
ECE10.821
FLNA0.816
TLN10.81
PTBP10.804
MOB3A0.788
SORBS30.785
TCF30.784
HDAC70.778
ASCC20.776

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.545
OR4F5-0.538
SMIM18-0.325
KLHL14-0.317
PPEF1-0.306
VWC2-0.3
CNTN5-0.293
HAPLN1-0.288
TYRP1-0.287
NEK10-0.284

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of CD151 mRNA"26377693
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of CD151 mRNA"21346803
D000082AcetaminophenAcetaminophen results in increased expression of CD151 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of CD151 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of CD151 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CD151 mRNA]17585979
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CD151 mRNA19770486
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CD151 mRNA16483693
D001104ArbutinArbutin results in decreased expression of CD151 mRNA17103032
D001151ArsenicArsenic results in increased methylation of CD151 gene24525453
D001241AspirinAspirin results in decreased expression of CD151 protein15381054
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CD151 mRNA26377693
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CD151 mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CD151 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CD151 mRNA26377693
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CD151 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CD151 mRNA22228805|2261060
D004958EstradiolEstradiol results in increased expression of CD151 mRNA19693291
C044887beta-methylcholinebeta-methylcholine affects the expression of CD151 mRNA21179406
C006780bisphenol Abisphenol A affects the expression of CD151 mRNA21786754
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CD151 mRNA21457566
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CD151 mRNA20883709
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA20360939
D002220CarbamazepineCarbamazepine results in decreased expression of CD151 mRNA11682256
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CD151 mRNA17484886
D002330CarmustineCarmustine results in decreased expression of CD151 mRNA15980968
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CD151 mRNA23650126
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CD151 mRNA27858113
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of CD151 mRNA17585979
D002994ClofibrateClofibrate results in decreased expression of CD151 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CD151 mRNA]17585979
C018021cobaltous chloridecobaltous chloride results in decreased expression of CD151 mRNA19376846
D003520CyclophosphamideCyclophosphamide results in increased expression of CD151 mRNA21041162
D016572CyclosporineCyclosporine results in increased expression of CD151 mRNA25562108
D003907DexamethasoneDexamethasone results in increased expression of CD151 mRNA21041162
D003976DiazinonDiazinon results in increased methylation of CD151 gene22964155
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CD151 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CD151 mRNA21266533
D002945CisplatinCD151 protein results in decreased susceptibility to Cisplatin16734730
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA20360939
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CD151 mRNA21041162
C540355fenamidonefenamidone results in increased expression of CD151 mRNA27029645
D005419FlavonoidsFlavonoids results in increased expression of CD151 mRNA18035473
D005485FlutamideFlutamide results in increased expression of CD151 mRNA24136188
D005947GlucoseCD151 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
C492448ICG 001ICG 001 results in increased expression of CD151 mRNA26191083
C410337K 7174K 7174 results in increased expression of CD151 mRNA24086573
D048628KetolidesKetolides analog results in increased expression of CD151 mRNA24967691
D008094LithiumLithium results in decreased expression of CD151 mRNA11682256
D008727MethotrexateCD151 protein affects the susceptibility to Methotrexate16217747
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CD151 mRNA26011545
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CD151 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of CD151 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CD151 mRNA]"20230807
C568376MT19c compoundMT19c compound results in decreased expression of CD151 mRNA21781307
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CD151 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CD151 mRNA"25554681
C017557nickel subsulfidenickel subsulfide results in increased expression of CD151 mRNA21086188
D009538Nicotine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of CD151 mRNA"20230807
D009538Nicotine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of CD151 mRNA]"20230807
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of CD151 mRNA25729387
D010100OxygenCD151 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
D011374ProgesteroneProgesterone affects the expression of CD151 mRNA23012394
C513428pyrachlostrobinpyrachlostrobin results in increased expression of CD151 mRNA27029645
D011794QuercetinQuercetin results in increased expression of CD151 mRNA21632981
D019821SimvastatinSimvastatin results in decreased expression of CD151 mRNA16414398
C017947sodium arsenitesodium arsenite results in increased expression of CD151 mRNA20883709
D012999SomanSoman results in increased expression of CD151 mRNA19281266
D013739TestosteroneTestosterone results in increased expression of CD151 mRNA19693291
C004648testosterone enanthatetestosterone enanthate affects the expression of CD151 mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CD151 mRNA23152189
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD151 mRNA21632981
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CD151 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CD151 promoter]19654925
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CD151 mRNA27865774
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of CD151 mRNA25729387
D019772TopotecanTopotecan results in increased expression of CD151 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of CD151 mRNA"19682533
D014635Valproic AcidValproic Acid results in decreased expression of CD151 mRNA29154799
D014635Valproic AcidValproic Acid results in increased methylation of CD151 gene29154799
D014635Valproic AcidValproic Acid affects the expression of CD151 mRNA17292431
D014635Valproic AcidValproic Acid results in decreased expression of CD151 mRNA11682256
D014640VancomycinVancomycin results in decreased expression of CD151 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of CD151 gene25560391
C029297vinylidene chloridevinylidene chloride results in increased expression of CD151 mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005178integrin binding-IDA17716972  27993971  
GO:0005178integrin binding-IPI24220332  
GO:0005515protein binding-IPI14676841  25416956  25910212  
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-NAS9602068  
GO:0007166cell surface receptor signaling pathway-IBA21873635  
GO:0030335positive regulation of cell migration-IDA17716972  
GO:0030335positive regulation of cell migration-IMP17716972  
GO:0031581hemidesmosome assembly-TAS-  
GO:0042098T cell proliferation-IEA-  
GO:0044319wound healing, spreading of cells-IDA17716972  
GO:0044319wound healing, spreading of cells-IMP17716972  
GO:0045807positive regulation of endocytosis-IDA17716972  
GO:0045807positive regulation of endocytosis-IMP17716972  
GO ID GO Term Qualifier Evidence PubMed
GO:0005604basement membrane-IDA23302890  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0005887integral component of plasma membrane-TAS8627808  
GO:0005925focal adhesion-HDA21423176  
GO:0009986cell surface-IDA17716972  
GO:0016020membrane-TAS8627808  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1474290Collagen formationTAS
R-HSA-1500931Cell-Cell communicationTAS
R-HSA-2022090Assembly of collagen fibrils and other multimeric structuresTAS
R-HSA-446107Type I hemidesmosome assemblyTAS
R-HSA-446728Cell junction organizationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24201754Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. (2013 Nov 26)Nankivell PBr J Cancer