SNP Detail Info-rs10007934

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

LOC105377441 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0087 (2636/29978,GnomAD)
A=0088 (2577/29118,TOPMED)
A=0061 (304/5008,1000G)
A=0069 (265/3854,ALSPAC)
A=0070 (259/3708,TWINSUK)

Position: chr4:136903447 (GRCh38.p7) (4q28.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 12 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.136903447G>A
GRCh37.p13 chr 4	NC_000004.11:g.137824601G>A

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105377441 transcript variant X1	XR_001741835.1:n.	N/A	Intron Variant
LOC105377441 transcript variant X2	XR_001741836.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.888	A=0.112
1000Genomes	American	Sub	694	G=0.950	A=0.050
1000Genomes	East Asian	Sub	1008	G=1.000	A=0.000
1000Genomes	Europe	Sub	1006	G=0.893	A=0.107
1000Genomes	Global	Study-wide	5008	G=0.939	A=0.061
1000Genomes	South Asian	Sub	978	G=0.990	A=0.010
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.931	A=0.069
The Genome Aggregation Database	African	Sub	8714	G=0.898	A=0.102
The Genome Aggregation Database	American	Sub	838	G=0.950	A=0.050
The Genome Aggregation Database	East Asian	Sub	1622	G=1.000	A=0.000
The Genome Aggregation Database	Europe	Sub	18502	G=0.909	A=0.091
The Genome Aggregation Database	Global	Study-wide	29978	G=0.912	A=0.087
The Genome Aggregation Database	Other	Sub	302	G=0.930	A=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.911	A=0.088
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.930	A=0.070

PMID	Title	Author	Journal
23953852	Genome-wide association studies of maximum number of drinks.	Pan Y	J Psychiatr Res

SNP ID	p-value	Traits	Study
rs10007934	2.08E-05	alcohol consumption	23953852

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	137784912	137785321	E068	-39280
chr4	137786354	137786480	E070	-38121
chr4	137786541	137786658	E070	-37943
chr4	137829397	137829675	E070	4796
chr4	137830903	137831046	E070	6302
chr4	137831060	137831174	E070	6459
chr4	137784912	137785321	E072	-39280
chr4	137802706	137803370	E081	-21231
chr4	137786105	137786191	E082	-38410
chr4	137786354	137786480	E082	-38121
chr4	137786541	137786658	E082	-37943
chr4	137802706	137803370	E082	-21231

rs10007934