rs10009538

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0014 (444/29948,GnomAD)
T=0021 (622/29118,TOPMED)
T=0020 (101/5008,1000G)
T=0000 (1/3854,ALSPAC)
T=0000 (0/3708,TWINSUK)
chr4:184971361 (GRCh38.p7) (4q35.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.184971361C>A
GRCh38.p7 chr 4NC_000004.12:g.184971361C>T
GRCh37.p13 chr 4NC_000004.11:g.185892515C>A
GRCh37.p13 chr 4NC_000004.11:g.185892515C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.930T=0.070
1000GenomesAmericanSub694C=0.990T=0.010
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=0.999T=0.001
1000GenomesGlobalStudy-wide5008C=0.980T=0.020
1000GenomesSouth AsianSub978C=1.000T=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8714C=0.950T=0.050
The Genome Aggregation DatabaseAmericanSub838C=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1620C=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18474C=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29948C=0.985T=0.014
The Genome Aggregation DatabaseOtherSub302C=1.000T=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.978T=0.021
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=1.000T=0.000
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100095388.52E-05alcohol dependence21314694

eQTL of rs10009538 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10009538 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr49813647398137210E07149154
chr49813647398137210E07249154
chr49813647398137210E08249154