rs10017041

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0213 (6378/29932,GnomAD)
C=0235 (6860/29118,TOPMED)
C=0248 (1243/5008,1000G)
C=0229 (882/3854,ALSPAC)
C=0236 (875/3708,TWINSUK)
chr4:179545156 (GRCh38.p7) (4q34.3)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.179545156T>C
GRCh37.p13 chr 4NC_000004.11:g.180466309T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.766C=0.234
1000GenomesAmericanSub694T=0.750C=0.250
1000GenomesEast AsianSub1008T=0.871C=0.129
1000GenomesEuropeSub1006T=0.770C=0.230
1000GenomesGlobalStudy-wide5008T=0.752C=0.248
1000GenomesSouth AsianSub978T=0.590C=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.771C=0.229
The Genome Aggregation DatabaseAfricanSub8710T=0.773C=0.227
The Genome Aggregation DatabaseAmericanSub834T=0.770C=0.230
The Genome Aggregation DatabaseEast AsianSub1614T=0.884C=0.116
The Genome Aggregation DatabaseEuropeSub18472T=0.787C=0.212
The Genome Aggregation DatabaseGlobalStudy-wide29932T=0.786C=0.213
The Genome Aggregation DatabaseOtherSub302T=0.640C=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.764C=0.235
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.764C=0.236
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100170410.00027alcohol dependence(early age of onset)20201924
rs100170410.00098alcohol dependence20201924

eQTL of rs10017041 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10017041 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4180452200180452448E068-13861
chr4180452200180452448E074-13861
chr4180452698180452852E074-13457
chr4180452926180452989E074-13320
chr4180424942180425888E081-40421
chr4180452698180452852E081-13457
chr4180452926180452989E081-13320
chr4180464919180465597E082-712