rs10037107

Homo sapiens
A>G
PPP2R2B : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0018 (552/29972,GnomAD)
G=0030 (887/29118,TOPMED)
G=0028 (139/5008,1000G)
G=0000 (0/3854,ALSPAC)
G=0000 (1/3708,TWINSUK)
chr5:146849539 (GRCh38.p7) (5q32)
AD
GWASdb2
1   publication(s)
See rs on genome
211 Enhancers around
74 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.146849539A>G
GRCh37.p13 chr 5NC_000005.9:g.146229102A>G
PPP2R2B RefSeqGeneNG_011570.1:g.236932T>C

Gene: PPP2R2B, protein phosphatase 2 regulatory subunit B, beta(minus strand)

Molecule type Change Amino acid[Codon] SO Term
PPP2R2B transcript variant 9NM_001271899.1:c.N/AIntron Variant
PPP2R2B transcript variant 8NM_001271900.1:c.N/AIntron Variant
PPP2R2B transcript variant 10NM_001271948.1:c.N/AIntron Variant
PPP2R2B transcript variant 2NM_181674.2:c.N/AIntron Variant
PPP2R2B transcript variant 3NM_181675.3:c.N/AIntron Variant
PPP2R2B transcript variant 4NM_181676.2:c.N/AIntron Variant
PPP2R2B transcript variant 5NM_181677.2:c.N/AIntron Variant
PPP2R2B transcript variant 6NM_181678.2:c.N/AIntron Variant
PPP2R2B transcript variant 11NR_073526.1:n.N/AIntron Variant
PPP2R2B transcript variant 12NR_073527.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.928G=0.072
1000GenomesAmericanSub694A=0.990G=0.010
1000GenomesEast AsianSub1008A=0.999G=0.001
1000GenomesEuropeSub1006A=0.998G=0.002
1000GenomesGlobalStudy-wide5008A=0.972G=0.028
1000GenomesSouth AsianSub978A=0.960G=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=1.000G=0.000
The Genome Aggregation DatabaseAfricanSub8726A=0.938G=0.062
The Genome Aggregation DatabaseAmericanSub838A=1.000G=0.000
The Genome Aggregation DatabaseEast AsianSub1620A=1.000G=0.000
The Genome Aggregation DatabaseEuropeSub18486A=0.999G=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29972A=0.981G=0.018
The Genome Aggregation DatabaseOtherSub302A=1.000G=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.969G=0.030
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=1.000G=0.000
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100371070.00017alcohol dependence21314694

eQTL of rs10037107 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10037107 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5146181477146181529E067-47573
chr5146181793146181843E067-47259
chr5146184794146184983E067-44119
chr5146185031146185126E067-43976
chr5146185216146185266E067-43836
chr5146185314146185400E067-43702
chr5146193261146193341E067-35761
chr5146193459146193606E067-35496
chr5146197763146197838E067-31264
chr5146198451146198686E067-30416
chr5146201567146201956E067-27146
chr5146201985146202068E067-27034
chr5146204731146204859E067-24243
chr5146206951146207094E067-22008
chr5146207932146208280E067-20822
chr5146208285146208357E067-20745
chr5146215911146216055E067-13047
chr5146216117146216179E067-12923
chr5146219396146219549E067-9553
chr5146229443146229685E067341
chr5146231737146231861E0672635
chr5146240122146240419E06711020
chr5146245277146245403E06716175
chr5146247590146247920E06718488
chr5146248043146248211E06718941
chr5146251239146251393E06722137
chr5146251880146251993E06722778
chr5146268047146268168E06738945
chr5146268320146268383E06739218
chr5146268771146268977E06739669
chr5146181477146181529E068-47573
chr5146181793146181843E068-47259
chr5146184794146184983E068-44119
chr5146185031146185126E068-43976
chr5146185216146185266E068-43836
chr5146185314146185400E068-43702
chr5146193055146193109E068-35993
chr5146193261146193341E068-35761
chr5146193459146193606E068-35496
chr5146194430146194486E068-34616
chr5146194542146194945E068-34157
chr5146195066146195214E068-33888
chr5146196577146196913E068-32189
chr5146197763146197838E068-31264
chr5146198451146198686E068-30416
chr5146198725146198818E068-30284
chr5146201567146201956E068-27146
chr5146201985146202068E068-27034
chr5146206951146207094E068-22008
chr5146207932146208280E068-20822
chr5146208285146208357E068-20745
chr5146212906146213251E068-15851
chr5146229443146229685E068341
chr5146231737146231861E0682635
chr5146247590146247920E06818488
chr5146268047146268168E06838945
chr5146268320146268383E06839218
chr5146268771146268977E06839669
chr5146269846146269908E06840744
chr5146270409146270654E06841307
chr5146271205146271315E06842103
chr5146271511146271854E06842409
chr5146271942146272075E06842840
chr5146274798146274900E06845696
chr5146181477146181529E069-47573
chr5146181793146181843E069-47259
chr5146184794146184983E069-44119
chr5146185031146185126E069-43976
chr5146185216146185266E069-43836
chr5146185314146185400E069-43702
chr5146193055146193109E069-35993
chr5146193261146193341E069-35761
chr5146193459146193606E069-35496
chr5146194430146194486E069-34616
chr5146194542146194945E069-34157
chr5146195066146195214E069-33888
chr5146197763146197838E069-31264
chr5146198451146198686E069-30416
chr5146198725146198818E069-30284
chr5146206951146207094E069-22008
chr5146207932146208280E069-20822
chr5146208285146208357E069-20745
chr5146215911146216055E069-13047
chr5146216117146216179E069-12923
chr5146229443146229685E069341
chr5146231737146231861E0692635
chr5146240122146240419E06911020
chr5146268047146268168E06938945
chr5146268320146268383E06939218
chr5146268771146268977E06939669
chr5146270409146270654E06941307
chr5146271205146271315E06942103
chr5146271511146271854E06942409
chr5146271942146272075E06942840
chr5146181477146181529E071-47573
chr5146181793146181843E071-47259
chr5146184794146184983E071-44119
chr5146185031146185126E071-43976
chr5146185216146185266E071-43836
chr5146185314146185400E071-43702
chr5146186325146186418E071-42684
chr5146188336146188753E071-40349
chr5146193055146193109E071-35993
chr5146193261146193341E071-35761
chr5146193459146193606E071-35496
chr5146194430146194486E071-34616
chr5146194542146194945E071-34157
chr5146195066146195214E071-33888
chr5146196577146196913E071-32189
chr5146197763146197838E071-31264
chr5146198451146198686E071-30416
chr5146198725146198818E071-30284
chr5146201567146201956E071-27146
chr5146201985146202068E071-27034
chr5146215911146216055E071-13047
chr5146216117146216179E071-12923
chr5146231737146231861E0712635
chr5146240122146240419E07111020
chr5146242109146242159E07113007
chr5146248043146248211E07118941
chr5146268047146268168E07138945
chr5146268320146268383E07139218
chr5146268771146268977E07139669
chr5146269846146269908E07140744
chr5146270409146270654E07141307
chr5146271942146272075E07142840
chr5146273662146273833E07144560
chr5146274206146274722E07145104
chr5146274798146274900E07145696
chr5146181477146181529E072-47573
chr5146181793146181843E072-47259
chr5146184794146184983E072-44119
chr5146185031146185126E072-43976
chr5146185216146185266E072-43836
chr5146185314146185400E072-43702
chr5146186325146186418E072-42684
chr5146186892146186952E072-42150
chr5146189170146189253E072-39849
chr5146189257146189339E072-39763
chr5146193055146193109E072-35993
chr5146193261146193341E072-35761
chr5146193459146193606E072-35496
chr5146194430146194486E072-34616
chr5146194542146194945E072-34157
chr5146195066146195214E072-33888
chr5146206951146207094E072-22008
chr5146207932146208280E072-20822
chr5146208285146208357E072-20745
chr5146229443146229685E072341
chr5146231737146231861E0722635
chr5146242109146242159E07213007
chr5146268047146268168E07238945
chr5146268320146268383E07239218
chr5146268771146268977E07239669
chr5146274206146274722E07245104
chr5146274798146274900E07245696
chr5146184794146184983E073-44119
chr5146193055146193109E073-35993
chr5146193261146193341E073-35761
chr5146193459146193606E073-35496
chr5146194430146194486E073-34616
chr5146194542146194945E073-34157
chr5146195066146195214E073-33888
chr5146201985146202068E073-27034
chr5146206951146207094E073-22008
chr5146229443146229685E073341
chr5146240122146240419E07311020
chr5146242109146242159E07313007
chr5146242345146242474E07313243
chr5146251880146251993E07322778
chr5146268771146268977E07339669
chr5146274206146274722E07345104
chr5146181477146181529E074-47573
chr5146181793146181843E074-47259
chr5146184794146184983E074-44119
chr5146185031146185126E074-43976
chr5146185216146185266E074-43836
chr5146185314146185400E074-43702
chr5146193055146193109E074-35993
chr5146193261146193341E074-35761
chr5146193459146193606E074-35496
chr5146194430146194486E074-34616
chr5146198451146198686E074-30416
chr5146198725146198818E074-30284
chr5146204731146204859E074-24243
chr5146206951146207094E074-22008
chr5146207932146208280E074-20822
chr5146208285146208357E074-20745
chr5146215911146216055E074-13047
chr5146216117146216179E074-12923
chr5146240122146240419E07411020
chr5146256060146256260E07426958
chr5146268047146268168E07438945
chr5146268320146268383E07439218
chr5146268771146268977E07439669
chr5146269846146269908E07440744
chr5146270409146270654E07441307
chr5146271942146272075E07442840
chr5146274798146274900E07445696
chr5146206951146207094E081-22008
chr5146207932146208280E081-20822
chr5146208285146208357E081-20745
chr5146229443146229685E081341
chr5146268047146268168E08138945
chr5146268320146268383E08139218
chr5146193459146193606E082-35496
chr5146198451146198686E082-30416
chr5146206951146207094E082-22008
chr5146207932146208280E082-20822
chr5146208285146208357E082-20745
chr5146251880146251993E08222778









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5146254978146255136E06725876
chr5146255669146255806E06726567
chr5146255895146255957E06726793
chr5146256656146256991E06727554
chr5146257005146257087E06727903
chr5146257133146257208E06728031
chr5146257209146257272E06728107
chr5146257349146258797E06728247
chr5146254978146255136E06825876
chr5146255669146255806E06826567
chr5146255895146255957E06826793
chr5146256656146256991E06827554
chr5146257005146257087E06827903
chr5146257133146257208E06828031
chr5146257209146257272E06828107
chr5146257349146258797E06828247
chr5146254978146255136E06925876
chr5146255669146255806E06926567
chr5146255895146255957E06926793
chr5146256656146256991E06927554
chr5146257005146257087E06927903
chr5146257133146257208E06928031
chr5146257209146257272E06928107
chr5146257349146258797E06928247
chr5146255669146255806E07026567
chr5146255895146255957E07026793
chr5146256656146256991E07027554
chr5146257005146257087E07027903
chr5146257133146257208E07028031
chr5146257209146257272E07028107
chr5146257349146258797E07028247
chr5146255895146255957E07126793
chr5146256656146256991E07127554
chr5146257005146257087E07127903
chr5146257133146257208E07128031
chr5146257209146257272E07128107
chr5146257349146258797E07128247
chr5146254978146255136E07225876
chr5146255669146255806E07226567
chr5146255895146255957E07226793
chr5146256656146256991E07227554
chr5146257005146257087E07227903
chr5146257133146257208E07228031
chr5146257209146257272E07228107
chr5146257349146258797E07228247
chr5146254978146255136E07325876
chr5146255669146255806E07326567
chr5146255895146255957E07326793
chr5146256656146256991E07327554
chr5146257005146257087E07327903
chr5146257133146257208E07328031
chr5146257209146257272E07328107
chr5146257349146258797E07328247
chr5146256656146256991E07427554
chr5146257005146257087E07427903
chr5146257133146257208E07428031
chr5146257209146257272E07428107
chr5146257349146258797E07428247
chr5146254978146255136E08125876
chr5146255669146255806E08126567
chr5146255895146255957E08126793
chr5146256656146256991E08127554
chr5146257005146257087E08127903
chr5146257133146257208E08128031
chr5146257209146257272E08128107
chr5146257349146258797E08128247
chr5146254978146255136E08225876
chr5146255669146255806E08226567
chr5146255895146255957E08226793
chr5146256656146256991E08227554
chr5146257005146257087E08227903
chr5146257133146257208E08228031
chr5146257209146257272E08228107
chr5146257349146258797E08228247