SNP Detail Info-rs10042504

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0392 (11764/29944,GnomAD)
G=0422 (12308/29118,TOPMED)
G=0412 (2061/5008,1000G)
G=0363 (1398/3854,ALSPAC)
G=0362 (1343/3708,TWINSUK)

Position: chr5:50386329 (GRCh38.p7) (5q11.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.50386329A>G
GRCh37.p13 chr 5	NC_000005.9:g.49682163A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.491	G=0.509
1000Genomes	American	Sub	694	A=0.670	G=0.330
1000Genomes	East Asian	Sub	1008	A=0.527	G=0.473
1000Genomes	Europe	Sub	1006	A=0.669	G=0.331
1000Genomes	Global	Study-wide	5008	A=0.588	G=0.412
1000Genomes	South Asian	Sub	978	A=0.640	G=0.360
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.637	G=0.363
The Genome Aggregation Database	African	Sub	8710	A=0.478	G=0.522
The Genome Aggregation Database	American	Sub	836	A=0.660	G=0.340
The Genome Aggregation Database	East Asian	Sub	1616	A=0.485	G=0.515
The Genome Aggregation Database	Europe	Sub	18480	A=0.675	G=0.324
The Genome Aggregation Database	Global	Study-wide	29944	A=0.607	G=0.392
The Genome Aggregation Database	Other	Sub	302	A=0.680	G=0.320
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.577	G=0.422
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.638	G=0.362

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10042504	0.0000915	alcoholism	pha002891
rs10042504	0.0000915	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
cg15950743	chr5:49708521	EMB	-0.08883063749868	1.0654e-35

rs10042504