rs1004584

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0258 (7714/29862,GnomAD)
T=0243 (7085/29118,TOPMED)
T=0296 (1480/5008,1000G)
T=0315 (1213/3854,ALSPAC)
T=0313 (1159/3708,TWINSUK)
chr7:35430618 (GRCh38.p7) (7p14.2)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
3 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.35430618C>T
GRCh37.p13 chr 7NC_000007.13:g.35470228C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.886T=0.114
1000GenomesAmericanSub694C=0.650T=0.350
1000GenomesEast AsianSub1008C=0.662T=0.338
1000GenomesEuropeSub1006C=0.668T=0.332
1000GenomesGlobalStudy-wide5008C=0.704T=0.296
1000GenomesSouth AsianSub978C=0.580T=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.685T=0.315
The Genome Aggregation DatabaseAfricanSub8698C=0.862T=0.138
The Genome Aggregation DatabaseAmericanSub834C=0.630T=0.370
The Genome Aggregation DatabaseEast AsianSub1614C=0.696T=0.304
The Genome Aggregation DatabaseEuropeSub18414C=0.694T=0.305
The Genome Aggregation DatabaseGlobalStudy-wide29862C=0.741T=0.258
The Genome Aggregation DatabaseOtherSub302C=0.680T=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.756T=0.243
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.687T=0.313
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs10045840.000154alcohol consumption23743675

eQTL of rs1004584 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1004584 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr73550541035505516E07035182
chr73550646735506536E07036239
chr73550541035505516E08135182
chr73548969335491153E08219465
chr73550541035505516E08235182



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr73549394535494430E07023717
chr73549444135494565E07324213
chr73549463235494938E08224404