rs10052295

Homo sapiens
A>G
CTNND2 : Intron Variant
LOC105374654 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0298 (8942/29938,GnomAD)
G=0336 (9785/29118,TOPMED)
G=0272 (1360/5008,1000G)
G=0255 (983/3854,ALSPAC)
G=0263 (975/3708,TWINSUK)
chr5:10977210 (GRCh38.p7) (5p15.2)
OD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.10977210A>G
GRCh37.p13 chr 5NC_000005.9:g.10977322A>G
CTNND2 RefSeqGeneNG_023544.1:g.931789T>C

Gene: CTNND2, catenin delta 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
CTNND2 transcript variant 2NM_001288715.1:c.N/AIntron Variant
CTNND2 transcript variant 3NM_001288716.1:c.N/AIntron Variant
CTNND2 transcript variant 4NM_001288717.1:c.N/AIntron Variant
CTNND2 transcript variant 1NM_001332.3:c.N/AIntron Variant
CTNND2 transcript variant 5NR_109988.1:n.N/AIntron Variant
CTNND2 transcript variant X1XM_005248251.3:c.N/AIntron Variant
CTNND2 transcript variant X2XM_005248252.2:c.N/AIntron Variant
CTNND2 transcript variant X3XM_005248253.1:c.N/AIntron Variant
CTNND2 transcript variant X4XM_011513967.2:c.N/AIntron Variant
CTNND2 transcript variant X5XM_017009072.1:c.N/AIntron Variant
CTNND2 transcript variant X6XM_017009073.1:c.N/AIntron Variant
CTNND2 transcript variant X7XM_017009074.1:c.N/AIntron Variant
CTNND2 transcript variant X8XM_017009075.1:c.N/AIntron Variant
CTNND2 transcript variant X9XM_017009076.1:c.N/AIntron Variant

Gene: LOC105374654, uncharacterized LOC105374654(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105374654 transcriptXR_925791.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.522G=0.478
1000GenomesAmericanSub694A=0.790G=0.210
1000GenomesEast AsianSub1008A=0.784G=0.216
1000GenomesEuropeSub1006A=0.751G=0.249
1000GenomesGlobalStudy-wide5008A=0.728G=0.272
1000GenomesSouth AsianSub978A=0.890G=0.110
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.745G=0.255
The Genome Aggregation DatabaseAfricanSub8708A=0.573G=0.427
The Genome Aggregation DatabaseAmericanSub838A=0.820G=0.180
The Genome Aggregation DatabaseEast AsianSub1616A=0.753G=0.247
The Genome Aggregation DatabaseEuropeSub18474A=0.752G=0.247
The Genome Aggregation DatabaseGlobalStudy-wide29938A=0.701G=0.298
The Genome Aggregation DatabaseOtherSub302A=0.690G=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.664G=0.336
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.737G=0.263
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs100522950.000162Opioid sensitivity23183491

eQTL of rs10052295 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10052295 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr51098808110988335E06710759
chr51098837010988464E06711048
chr51098882110990667E06711499
chr51100750711007788E06730185
chr51100787511007929E06730553
chr51098689110987067E0689569
chr51098719810987313E0689876
chr51098753110987620E06810209
chr51098808110988335E06810759
chr51098837010988464E06811048
chr51098882110990667E06811499
chr51100750711007788E06830185
chr51100787511007929E06830553
chr51100807311008177E06830751
chr51098808110988335E06910759
chr51098837010988464E06911048
chr51098882110990667E06911499
chr51098808110988335E07110759
chr51098837010988464E07111048
chr51098882110990667E07111499
chr51101016711010217E07132845
chr51101068611010756E07133364
chr51101081711011272E07133495
chr51098292810982993E0725606
chr51098417210984226E0726850
chr51098428910984381E0726967
chr51098808110988335E07210759
chr51098837010988464E07211048
chr51098882110990667E07211499
chr51098837010988464E07311048
chr51098882110990667E07311499
chr51102350511023760E07346183
chr51098292810982993E0745606
chr51098808110988335E07410759
chr51098837010988464E07411048
chr51098882110990667E07411499
chr51100750711007788E07430185
chr51100787511007929E07430553
chr51100807311008177E07430751
chr51093426210934333E081-42989
chr51093498110935024E081-42298
chr51098417210984226E0816850
chr51098428910984381E0816967
chr51098447610984516E0817154
chr51098454110984683E0817219
chr51098808110988335E08110759
chr51098837010988464E08111048
chr51102397111024489E08246649