rs10063505

Homo sapiens
C>A
MYO10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0113 (3354/29648,GnomAD)
C==0155 (4527/29118,TOPMED)
C==0138 (693/5008,1000G)
C==0040 (156/3854,ALSPAC)
C==0039 (145/3708,TWINSUK)
chr5:16822062 (GRCh38.p7) (5p15.1)
AD
GWASdb2
1   publication(s)
See rs on genome
77 Enhancers around
16 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.16822062C>A
GRCh37.p13 chr 5NC_000005.9:g.16822171C>A

Gene: MYO10, myosin X(minus strand)

Molecule type Change Amino acid[Codon] SO Term
MYO10 transcriptNM_012334.2:c.N/AIntron Variant
MYO10 transcript variant X1XM_006714475.2:c.N/AIntron Variant
MYO10 transcript variant X2XM_005248306.4:c.N/AGenic Upstream Transcript Variant
MYO10 transcript variant X4XM_005248307.2:c.N/AGenic Upstream Transcript Variant
MYO10 transcript variant X3XM_011514046.2:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.352A=0.648
1000GenomesAmericanSub694C=0.160A=0.840
1000GenomesEast AsianSub1008C=0.040A=0.960
1000GenomesEuropeSub1006C=0.042A=0.958
1000GenomesGlobalStudy-wide5008C=0.138A=0.862
1000GenomesSouth AsianSub978C=0.030A=0.970
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.040A=0.960
The Genome Aggregation DatabaseAfricanSub8630C=0.286A=0.714
The Genome Aggregation DatabaseAmericanSub834C=0.150A=0.850
The Genome Aggregation DatabaseEast AsianSub1620C=0.036A=0.964
The Genome Aggregation DatabaseEuropeSub18262C=0.037A=0.962
The Genome Aggregation DatabaseGlobalStudy-wide29648C=0.113A=0.886
The Genome Aggregation DatabaseOtherSub302C=0.090A=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.155A=0.844
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.039A=0.961
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100635050.000886alcohol dependence20201924

eQTL of rs10063505 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10063505 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr51678533116785524E067-36647
chr51680933816810567E067-11604
chr51677422216774413E070-47758
chr51678047116780681E070-41490
chr51679191316792024E070-30147
chr51679209616792222E070-29949
chr51679226316792336E070-29835
chr51679235916792450E070-29721
chr51679245516792696E070-29475
chr51679273716793347E070-28824
chr51680933816810567E070-11604
chr51685531116855524E07033140
chr51685563116856123E07033460
chr51678533116785524E071-36647
chr51679122216791858E071-30313
chr51680933816810567E071-11604
chr51683599816836587E07113827
chr51683675816836808E07114587
chr51684136116841691E07119190
chr51678494816784998E072-37173
chr51678533116785524E072-36647
chr51678533116785524E073-36647
chr51680826416808457E073-13714
chr51680913616809322E073-12849
chr51680933816810567E073-11604
chr51684136116841691E07419190
chr51684173316842023E07419562
chr51685563116856123E07433460
chr51678237916782456E081-39715
chr51678308416783134E081-39037
chr51678494816784998E081-37173
chr51678533116785524E081-36647
chr51679122216791858E081-30313
chr51679191316792024E081-30147
chr51679209616792222E081-29949
chr51679226316792336E081-29835
chr51679235916792450E081-29721
chr51679245516792696E081-29475
chr51679273716793347E081-28824
chr51679412216794176E081-27995
chr51679437516794770E081-27401
chr51680002516800189E081-21982
chr51680136416801423E081-20748
chr51680152116801943E081-20228
chr51680678416808043E081-14128
chr51680913616809322E081-12849
chr51680933816810567E081-11604
chr51681077916810839E081-11332
chr51681940616820060E081-2111
chr51682026416820464E081-1707
chr51683880216839049E08116631
chr51684277416842844E08120603
chr51684290416843065E08120733
chr51684306616843411E08120895
chr51684359816843642E08121427
chr51685784416858042E08135673
chr51685807116858217E08135900
chr51686434716864441E08142176
chr51686464716865280E08142476
chr51686532016865535E08143149
chr51679122216791858E082-30313
chr51679191316792024E082-30147
chr51679209616792222E082-29949
chr51679226316792336E082-29835
chr51679235916792450E082-29721
chr51679245516792696E082-29475
chr51679273716793347E082-28824
chr51679437516794770E082-27401
chr51680678416808043E082-14128
chr51680913616809322E082-12849
chr51680933816810567E082-11604
chr51681940616820060E082-2111
chr51683880216839049E08216631
chr51686464716865280E08242476
chr51686532016865535E08243149
chr51686654816866876E08244377
chr51686694116867580E08244770








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr51682652916826787E0674358
chr51682696416827086E0674793
chr51682718816827268E0675017
chr51682652916826787E0684358
chr51682696416827086E0684793
chr51682696416827086E0694793
chr51682718816827268E0695017
chr51682652916826787E0724358
chr51682696416827086E0724793
chr51682718816827268E0725017
chr51682696416827086E0734793
chr51682718816827268E0735017
chr51682696416827086E0814793
chr51682652916826787E0824358
chr51682696416827086E0824793
chr51682718816827268E0825017