rs10065963

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0212 (6374/29944,GnomAD)
T=0156 (4541/29118,TOPMED)
T=0220 (1101/5008,1000G)
T=0253 (975/3854,ALSPAC)
T=0245 (908/3708,TWINSUK)
chr5:121441072 (GRCh38.p7) (5q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.121441072C>T
GRCh37.p13 chr 5NC_000005.9:g.120776767C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.976T=0.024
1000GenomesAmericanSub694C=0.810T=0.190
1000GenomesEast AsianSub1008C=0.489T=0.511
1000GenomesEuropeSub1006C=0.758T=0.242
1000GenomesGlobalStudy-wide5008C=0.780T=0.220
1000GenomesSouth AsianSub978C=0.820T=0.180
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.747T=0.253
The Genome Aggregation DatabaseAfricanSub8720C=0.951T=0.049
The Genome Aggregation DatabaseAmericanSub836C=0.840T=0.160
The Genome Aggregation DatabaseEast AsianSub1612C=0.512T=0.488
The Genome Aggregation DatabaseEuropeSub18474C=0.732T=0.267
The Genome Aggregation DatabaseGlobalStudy-wide29944C=0.787T=0.212
The Genome Aggregation DatabaseOtherSub302C=0.760T=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.844T=0.156
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.755T=0.245
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100659630.000556alcohol dependence20201924

eQTL of rs10065963 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10065963 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5120750901120751274E070-25493
chr5120751497120751556E070-25211