SNP Detail Info-rs10070748

Organism: Homo sapiens

Alleles: A>C

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C=0352 (10525/29822,GnomAD)
C=0449 (13085/29118,TOPMED)
C=0476 (2382/5008,1000G)
C=0199 (768/3854,ALSPAC)
C=0189 (701/3708,TWINSUK)

Position: chr5:26315360 (GRCh38.p7) (5p14.1)

Phenotype: CD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.26315360A>C
GRCh37.p13 chr 5	NC_000005.9:g.26315469A>C

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.196	C=0.804
1000Genomes	American	Sub	694	A=0.700	C=0.300
1000Genomes	East Asian	Sub	1008	A=0.507	C=0.493
1000Genomes	Europe	Sub	1006	A=0.781	C=0.219
1000Genomes	Global	Study-wide	5008	A=0.524	C=0.476
1000Genomes	South Asian	Sub	978	A=0.590	C=0.410
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.801	C=0.199
The Genome Aggregation Database	African	Sub	8682	A=0.290	C=0.710
The Genome Aggregation Database	American	Sub	834	A=0.690	C=0.310
The Genome Aggregation Database	East Asian	Sub	1572	A=0.534	C=0.466
The Genome Aggregation Database	Europe	Sub	18434	A=0.822	C=0.177
The Genome Aggregation Database	Global	Study-wide	29822	A=0.647	C=0.352
The Genome Aggregation Database	Other	Sub	300	A=0.640	C=0.360
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.550	C=0.449
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.811	C=0.189

PMID	Title	Author	Journal
23958962	Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.	Gelernter J	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs10070748	8.13E-06	cocaine dependence	23958962

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs10070748