rs10096565

Homo sapiens
A>C / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
C=0224 (6724/29912,GnomAD)
C=0272 (1361/5008,1000G)
C=0259 (998/3854,ALSPAC)
C=0252 (934/3708,TWINSUK)
chr8:57757793 (GRCh38.p7) (8q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
195 Enhancers around
40 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.57757793A>C
GRCh38.p7 chr 8NC_000008.11:g.57757793A>T
GRCh37.p13 chr 8NC_000008.10:g.58670352A>C
GRCh37.p13 chr 8NC_000008.10:g.58670352A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.870C=0.130
1000GenomesAmericanSub694A=0.750C=0.250
1000GenomesEast AsianSub1008A=0.596C=0.404
1000GenomesEuropeSub1006A=0.738C=0.262
1000GenomesGlobalStudy-wide5008A=0.728C=0.272
1000GenomesSouth AsianSub978A=0.650C=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.741C=0.259
The Genome Aggregation DatabaseAfricanSub8714A=0.863C=0.137
The Genome Aggregation DatabaseAmericanSub830A=0.720C=0.28,
The Genome Aggregation DatabaseEast AsianSub1602A=0.566C=0.434
The Genome Aggregation DatabaseEuropeSub18464A=0.753C=0.246
The Genome Aggregation DatabaseGlobalStudy-wide29912A=0.775C=0.224
The Genome Aggregation DatabaseOtherSub302A=0.790C=0.20,
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.748C=0.252
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs100965650.00041alcohol dependence24277619

eQTL of rs10096565 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10096565 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr81861328718614152E067-42198
chr81866344118663493E0677091
chr81866353918663672E0677189
chr81866747318667523E06711123
chr81866754718667671E06711197
chr81866772418667818E06711374
chr81869647818697636E06740128
chr81869772918697870E06741379
chr81869798918698335E06741639
chr81869835518698439E06742005
chr81869859018698914E06742240
chr81869895518699273E06742605
chr81869927818699343E06742928
chr81869941718699876E06743067
chr81870197618702082E06745626
chr81870210118702192E06745751
chr81870229018702517E06745940
chr81870269618702770E06746346
chr81870282118703189E06746471
chr81870509018705140E06748740
chr81861536418615411E068-40939
chr81861549518615539E068-40811
chr81861572018615770E068-40580
chr81861583918615883E068-40467
chr81861595318616111E068-40239
chr81861626618616680E068-39670
chr81862608618626167E068-30183
chr81866197418662151E0685624
chr81866217718662298E0685827
chr81866230118662363E0685951
chr81866344118663493E0687091
chr81866353918663672E0687189
chr81866382318663917E0687473
chr81866403418664112E0687684
chr81866411718664176E0687767
chr81866418718664238E0687837
chr81866430518664356E0687955
chr81866442618664504E0688076
chr81866453318664590E0688183
chr81869196318692120E06835613
chr81869647818697636E06840128
chr81869772918697870E06841379
chr81869798918698335E06841639
chr81869835518698439E06842005
chr81869859018698914E06842240
chr81869895518699273E06842605
chr81869927818699343E06842928
chr81869941718699876E06843067
chr81870197618702082E06845626
chr81870210118702192E06845751
chr81870229018702517E06845940
chr81870269618702770E06846346
chr81870282118703189E06846471
chr81870365718705062E06847307
chr81870509018705140E06848740
chr81862594418626031E069-30319
chr81862608618626167E069-30183
chr81862618218626343E069-30007
chr81864634218646451E069-9899
chr81866326018663312E0696910
chr81866344118663493E0697091
chr81866353918663672E0697189
chr81866382318663917E0697473
chr81866403418664112E0697684
chr81866411718664176E0697767
chr81866418718664238E0697837
chr81866430518664356E0697955
chr81866442618664504E0698076
chr81866453318664590E0698183
chr81866684018666911E06910490
chr81869647818697636E06940128
chr81869772918697870E06941379
chr81869798918698335E06941639
chr81869835518698439E06942005
chr81869859018698914E06942240
chr81869895518699273E06942605
chr81869927818699343E06942928
chr81869941718699876E06943067
chr81870229018702517E06945940
chr81870269618702770E06946346
chr81870282118703189E06946471
chr81870365718705062E06947307
chr81870509018705140E06948740
chr81861626618616680E070-39670
chr81861328718614152E071-42198
chr81861572018615770E071-40580
chr81862727518627355E071-28995
chr81862746818627824E071-28526
chr81864661118646727E071-9623
chr81866353918663672E0717189
chr81866382318663917E0717473
chr81866403418664112E0717684
chr81866411718664176E0717767
chr81866418718664238E0717837
chr81866430518664356E0717955
chr81866442618664504E0718076
chr81866453318664590E0718183
chr81866747318667523E07111123
chr81866754718667671E07111197
chr81867152718671668E07115177
chr81867173818672073E07115388
chr81867219018672444E07115840
chr81869160518691661E07135255
chr81869196318692120E07135613
chr81869647818697636E07140128
chr81869772918697870E07141379
chr81869798918698335E07141639
chr81869835518698439E07142005
chr81869859018698914E07142240
chr81869895518699273E07142605
chr81869927818699343E07142928
chr81869941718699876E07143067
chr81870197618702082E07145626
chr81870210118702192E07145751
chr81870229018702517E07145940
chr81870269618702770E07146346
chr81870282118703189E07146471
chr81870509018705140E07148740
chr81864709118647460E072-8890
chr81865633718656815E0720
chr81865682618656998E072476
chr81866747318667523E07211123
chr81866754718667671E07211197
chr81869196318692120E07235613
chr81869647818697636E07240128
chr81869772918697870E07241379
chr81869798918698335E07241639
chr81869835518698439E07242005
chr81869859018698914E07242240
chr81869895518699273E07242605
chr81869927818699343E07242928
chr81869941718699876E07243067
chr81869996818700018E07243618
chr81870197618702082E07245626
chr81870210118702192E07245751
chr81870229018702517E07245940
chr81870269618702770E07246346
chr81870282118703189E07246471
chr81870365718705062E07247307
chr81870509018705140E07248740
chr81861328718614152E073-42198
chr81867219018672444E07315840
chr81869196318692120E07335613
chr81869647818697636E07340128
chr81869772918697870E07341379
chr81869798918698335E07341639
chr81869835518698439E07342005
chr81869859018698914E07342240
chr81869895518699273E07342605
chr81869927818699343E07342928
chr81869941718699876E07343067
chr81869996818700018E07343618
chr81870197618702082E07345626
chr81870210118702192E07345751
chr81870229018702517E07345940
chr81870269618702770E07346346
chr81870282118703189E07346471
chr81870509018705140E07348740
chr81861536418615411E074-40939
chr81861626618616680E074-39670
chr81861719518617245E074-39105
chr81862608618626167E074-30183
chr81862618218626343E074-30007
chr81862746818627824E074-28526
chr81862790818628720E074-27630
chr81866353918663672E0747189
chr81866418718664238E0747837
chr81866430518664356E0747955
chr81866442618664504E0748076
chr81866453318664590E0748183
chr81866684018666911E07410490
chr81867173818672073E07415388
chr81867219018672444E07415840
chr81869196318692120E07435613
chr81869647818697636E07440128
chr81869772918697870E07441379
chr81869798918698335E07441639
chr81869835518698439E07442005
chr81869859018698914E07442240
chr81869895518699273E07442605
chr81869927818699343E07442928
chr81869941718699876E07443067
chr81869996818700018E07443618
chr81870229018702517E07445940
chr81870269618702770E07446346
chr81870282118703189E07446471
chr81870365718705062E07447307
chr81870509018705140E07448740
chr81860641118606479E081-49871
chr81861328718614152E081-42198
chr81861549518615539E081-40811
chr81861595318616111E081-40239
chr81865682618656998E082476
chr81869859018698914E08242240
chr81869895518699273E08242605










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr81866468418665063E0678334
chr81866515218665440E0678802
chr81866547918665586E0679129
chr81866568918665751E0679339
chr81866599918666112E0679649
chr81866627118666619E0679921
chr81866468418665063E0688334
chr81866515218665440E0688802
chr81866547918665586E0689129
chr81866568918665751E0689339
chr81866599918666112E0689649
chr81866627118666619E0689921
chr81866468418665063E0698334
chr81866515218665440E0698802
chr81866547918665586E0699129
chr81866568918665751E0699339
chr81866599918666112E0699649
chr81866627118666619E0699921
chr81866468418665063E0718334
chr81866515218665440E0718802
chr81866547918665586E0719129
chr81866568918665751E0719339
chr81866599918666112E0719649
chr81866627118666619E0719921
chr81866468418665063E0728334
chr81866515218665440E0728802
chr81866547918665586E0729129
chr81866568918665751E0729339
chr81866599918666112E0729649
chr81866627118666619E0729921
chr81866468418665063E0738334
chr81866515218665440E0738802
chr81866599918666112E0739649
chr81866627118666619E0739921
chr81866468418665063E0748334
chr81866515218665440E0748802
chr81866547918665586E0749129
chr81866568918665751E0749339
chr81866599918666112E0749649
chr81866627118666619E0749921