rs10097146

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0381 (11431/29934,GnomAD)
A=0215 (1077/5008,1000G)
A=0471 (1815/3854,ALSPAC)
A=0463 (1715/3708,TWINSUK)
chr8:16701221 (GRCh38.p7) (8p22)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.16701221G>A
GRCh37.p13 chr 8NC_000008.10:g.16558730G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.793A=0.207
1000GenomesAmericanSub694G=0.700A=0.300
1000GenomesEast AsianSub1008G=0.988A=0.012
1000GenomesEuropeSub1006G=0.548A=0.452
1000GenomesGlobalStudy-wide5008G=0.785A=0.215
1000GenomesSouth AsianSub978G=0.870A=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.529A=0.471
The Genome Aggregation DatabaseAfricanSub8724G=0.751A=0.249
The Genome Aggregation DatabaseAmericanSub838G=0.720A=0.280
The Genome Aggregation DatabaseEast AsianSub1614G=0.984A=0.016
The Genome Aggregation DatabaseEuropeSub18456G=0.518A=0.481
The Genome Aggregation DatabaseGlobalStudy-wide29934G=0.618A=0.381
The Genome Aggregation DatabaseOtherSub302G=0.600A=0.400
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.537A=0.463
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs100971460.00014alcohol dependence20201924

eQTL of rs10097146 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10097146 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr81654727516547419E070-11311
chr81654742616547751E070-10979