rs10112899

Homo sapiens
G>A / G>C
None
Check p-value
SNV (Single Nucleotide Variation)
A=0068 (2050/29980,GnomAD)
A=0063 (1860/29118,TOPMED)
A=0091 (457/5008,1000G)
A=0069 (267/3854,ALSPAC)
A=0070 (261/3708,TWINSUK)
chr8:52846326 (GRCh38.p7) (8q11.23)
AD
GWASdb2
1   publication(s)
See rs on genome
170 Enhancers around
75 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.52846326G>A
GRCh38.p7 chr 8NC_000008.11:g.52846326G>C
GRCh37.p13 chr 8NC_000008.10:g.53758886G>A
GRCh37.p13 chr 8NC_000008.10:g.53758886G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.932A=0.068
1000GenomesAmericanSub694G=0.950A=0.050
1000GenomesEast AsianSub1008G=0.988A=0.012
1000GenomesEuropeSub1006G=0.918A=0.082
1000GenomesGlobalStudy-wide5008G=0.909A=0.091
1000GenomesSouth AsianSub978G=0.760A=0.240
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.931A=0.069
The Genome Aggregation DatabaseAfricanSub8724G=0.942C=0.000
The Genome Aggregation DatabaseAmericanSub838G=0.950C=0.00,
The Genome Aggregation DatabaseEast AsianSub1614G=0.989C=0.000
The Genome Aggregation DatabaseEuropeSub18502G=0.921C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29980G=0.931C=0.000
The Genome Aggregation DatabaseOtherSub302G=0.910C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.936A=0.063
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.930A=0.070
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101128990.000797alcohol dependence21314694

eQTL of rs10112899 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10112899 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8630409630851E067-28385
chr8630954631776E067-27460
chr8652417652507E067-6729
chr8652741652876E067-6360
chr8676508676624E06717272
chr8676682676789E06717446
chr8676925677013E06717689
chr8677123677222E06717887
chr8677259677470E06718023
chr8677472677570E06718236
chr8677831677913E06718595
chr8679031679112E06719795
chr8679243679287E06720007
chr8679399679491E06720163
chr8652741652876E068-6360
chr8652910653004E068-6232
chr8677123677222E06817887
chr8677259677470E06818023
chr8703679703738E06844443
chr8630409630851E069-28385
chr8630954631776E069-27460
chr8643707643874E069-15362
chr8643885643965E069-15271
chr8644187644377E069-14859
chr8644439644503E069-14733
chr8642277642412E070-16824
chr8642505642588E070-16648
chr8642677643212E070-16024
chr8671354671850E07012118
chr8672940673020E07013704
chr8674399674627E07015163
chr8674710674770E07015474
chr8674775674869E07015539
chr8674889674969E07015653
chr8675081675216E07015845
chr8675250675304E07016014
chr8676306676404E07017070
chr8676508676624E07017272
chr8676682676789E07017446
chr8676925677013E07017689
chr8677123677222E07017887
chr8677259677470E07018023
chr8677472677570E07018236
chr8677831677913E07018595
chr8678089678459E07018853
chr8678630678680E07019394
chr8678694678744E07019458
chr8678829678884E07019593
chr8679031679112E07019795
chr8679243679287E07020007
chr8679399679491E07020163
chr8630409630851E071-28385
chr8630954631776E071-27460
chr8643707643874E071-15362
chr8643885643965E071-15271
chr8644187644377E071-14859
chr8670354670993E07111118
chr8678829678884E07119593
chr8679031679112E07119795
chr8679243679287E07120007
chr8679399679491E07120163
chr8630409630851E072-28385
chr8630954631776E072-27460
chr8644439644503E072-14733
chr8652741652876E072-6360
chr8652910653004E072-6232
chr8653126653205E072-6031
chr8676508676624E07217272
chr8676682676789E07217446
chr8676925677013E07217689
chr8677123677222E07217887
chr8677259677470E07218023
chr8677472677570E07218236
chr8677831677913E07218595
chr8678089678459E07218853
chr8678630678680E07219394
chr8678694678744E07219458
chr8678829678884E07219593
chr8679031679112E07219795
chr8679243679287E07220007
chr8704039704107E07244803
chr8676508676624E07317272
chr8676682676789E07317446
chr8676925677013E07317689
chr8677123677222E07317887
chr8677259677470E07318023
chr8677472677570E07318236
chr8679243679287E07320007
chr8679399679491E07320163
chr8703070703114E07343834
chr8630409630851E074-28385
chr8630954631776E074-27460
chr8644439644503E074-14733
chr8652417652507E074-6729
chr8614071614205E081-45031
chr8614297614400E081-44836
chr8614460614500E081-44736
chr8614585614684E081-44552
chr8614791615212E081-44024
chr8615299615375E081-43861
chr8615441615538E081-43698
chr8615678615821E081-43415
chr8615832615968E081-43268
chr8616499616610E081-42626
chr8616866616916E081-42320
chr8617313617363E081-41873
chr8617401617469E081-41767
chr8618256618833E081-40403
chr8618863618921E081-40315
chr8618990619069E081-40167
chr8619803619853E081-39383
chr8620087620137E081-39099
chr8620335620385E081-38851
chr8620521620575E081-38661
chr8620581620634E081-38602
chr8620726620776E081-38460
chr8624186624244E081-34992
chr8624761624815E081-34421
chr8624823624863E081-34373
chr8624988625104E081-34132
chr8630409630851E081-28385
chr8630954631776E081-27460
chr8636413636453E081-22783
chr8638888638971E081-20265
chr8638987639075E081-20161
chr8640566640633E081-18603
chr8641228641561E081-17675
chr8642277642412E081-16824
chr8642505642588E081-16648
chr8642677643212E081-16024
chr8643480643565E081-15671
chr8643707643874E081-15362
chr8643885643965E081-15271
chr8674399674627E08115163
chr8674710674770E08115474
chr8674775674869E08115539
chr8675826675876E08116590
chr8676925677013E08117689
chr8677123677222E08117887
chr8677259677470E08118023
chr8677472677570E08118236
chr8677831677913E08118595
chr8678089678459E08118853
chr8678630678680E08119394
chr8678694678744E08119458
chr8678829678884E08119593
chr8679031679112E08119795
chr8679243679287E08120007
chr8679399679491E08120163
chr8617313617363E082-41873
chr8617401617469E082-41767
chr8640566640633E082-18603
chr8642277642412E082-16824
chr8642505642588E082-16648
chr8642677643212E082-16024
chr8643480643565E082-15671
chr8673869674397E08214633
chr8674399674627E08215163
chr8674710674770E08215474
chr8674775674869E08215539
chr8674889674969E08215653
chr8676925677013E08217689
chr8677123677222E08217887
chr8677259677470E08218023
chr8677472677570E08218236
chr8677831677913E08218595
chr8678089678459E08218853
chr8678630678680E08219394
chr8678694678744E08219458
chr8678829678884E08219593










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8623469623941E067-35295
chr8636571638835E067-20401
chr8680455682058E06721219
chr8686866687059E06727630
chr8687138687201E06727902
chr8687270687798E06728034
chr8687907687957E06728671
chr8688024688187E06728788
chr8688198688289E06728962
chr8688330689405E06729094
chr8636571638835E068-20401
chr8680455682058E06821219
chr8687138687201E06827902
chr8687270687798E06828034
chr8687907687957E06828671
chr8688024688187E06828788
chr8688198688289E06828962
chr8688330689405E06829094
chr8689417689525E06830181
chr8623469623941E069-35295
chr8636571638835E069-20401
chr8680455682058E06921219
chr8686866687059E06927630
chr8687138687201E06927902
chr8687270687798E06928034
chr8687907687957E06928671
chr8688024688187E06928788
chr8688198688289E06928962
chr8688330689405E06929094
chr8689417689525E06930181
chr8636571638835E070-20401
chr8680455682058E07021219
chr8687138687201E07027902
chr8687270687798E07028034
chr8687907687957E07028671
chr8636571638835E071-20401
chr8680455682058E07121219
chr8687138687201E07127902
chr8687270687798E07128034
chr8687907687957E07128671
chr8688024688187E07128788
chr8689417689525E07130181
chr8623469623941E072-35295
chr8636571638835E072-20401
chr8680455682058E07221219
chr8686866687059E07227630
chr8687138687201E07227902
chr8687270687798E07228034
chr8687907687957E07228671
chr8688024688187E07228788
chr8688198688289E07228962
chr8688330689405E07229094
chr8689417689525E07230181
chr8623469623941E073-35295
chr8636571638835E073-20401
chr8680455682058E07321219
chr8686866687059E07327630
chr8687138687201E07327902
chr8687270687798E07328034
chr8687907687957E07328671
chr8688024688187E07328788
chr8688198688289E07328962
chr8688330689405E07329094
chr8689417689525E07330181
chr8680455682058E07421219
chr8623469623941E082-35295
chr8636571638835E082-20401
chr8680455682058E08221219
chr8686866687059E08227630
chr8687138687201E08227902
chr8687270687798E08228034
chr8687907687957E08228671
chr8688024688187E08228788
chr8688198688289E08228962
chr8688330689405E08229094