rs10113582

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0060 (1811/29872,GnomAD)
C=0050 (1461/29118,TOPMED)
C=0076 (381/5008,1000G)
C=0079 (304/3854,ALSPAC)
C=0070 (258/3708,TWINSUK)
chr8:117796654 (GRCh38.p7) (8q24.11)
AD
GWASdb2
1   publication(s)
See rs on genome
36 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.117796654T>C
GRCh37.p13 chr 8NC_000008.10:g.118808893T>C
EXT1 RefSeqGene LRG_493

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.988C=0.012
1000GenomesAmericanSub694T=0.960C=0.040
1000GenomesEast AsianSub1008T=0.806C=0.194
1000GenomesEuropeSub1006T=0.926C=0.074
1000GenomesGlobalStudy-wide5008T=0.924C=0.076
1000GenomesSouth AsianSub978T=0.930C=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.921C=0.079
The Genome Aggregation DatabaseAfricanSub8722T=0.980C=0.020
The Genome Aggregation DatabaseAmericanSub832T=0.930C=0.070
The Genome Aggregation DatabaseEast AsianSub1614T=0.809C=0.191
The Genome Aggregation DatabaseEuropeSub18404T=0.931C=0.068
The Genome Aggregation DatabaseGlobalStudy-wide29872T=0.939C=0.060
The Genome Aggregation DatabaseOtherSub300T=0.950C=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.949C=0.050
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.930C=0.070
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs101135824.3E-05alcoholism (heaviness of drinking)21529783

eQTL of rs10113582 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10113582 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8118806332118806706E069-2187
chr8118849506118849775E06940613
chr8118849853118849941E06940960
chr8118850253118850533E06941360
chr8118824709118825206E07015816
chr8118844782118844906E07035889
chr8118844930118845570E07036037
chr8118848731118848806E07039838
chr8118849409118849494E07040516
chr8118849506118849775E07040613
chr8118849853118849941E07040960
chr8118850253118850533E07041360
chr8118850611118850795E07041718
chr8118851020118851070E07042127
chr8118853922118853983E07045029
chr8118806332118806706E071-2187
chr8118849409118849494E07140516
chr8118849506118849775E07140613
chr8118849853118849941E07140960
chr8118806332118806706E072-2187
chr8118849853118849941E07240960
chr8118806332118806706E074-2187
chr8118849506118849775E07440613
chr8118849853118849941E07440960
chr8118809174118809313E081281
chr8118809373118809518E081480
chr8118819221118819354E08110328
chr8118819456118819616E08110563
chr8118819703118819793E08110810
chr8118822171118822379E08113278
chr8118822536118822936E08113643
chr8118823096118823239E08114203
chr8118824709118825206E08115816
chr8118808728118808904E0820
chr8118850253118850533E08241360
chr8118850611118850795E08241718