SNP Detail Info-rs10115971

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0168 (5053/29956,GnomAD)
G=0150 (4391/29118,TOPMED)
G=0160 (803/5008,1000G)
G=0186 (715/3854,ALSPAC)
G=0167 (618/3708,TWINSUK)

Position: chr9:98262605 (GRCh38.p7) (9q22.33)

Phenotype: AD

Dataset:

GWASdb2

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 39 Enhancers around

Promoter: 10 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.98262605A>G
GRCh37.p13 chr 9	NC_000009.11:g.101024887A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.885	G=0.115
1000Genomes	American	Sub	694	A=0.800	G=0.200
1000Genomes	East Asian	Sub	1008	A=0.839	G=0.161
1000Genomes	Europe	Sub	1006	A=0.816	G=0.184
1000Genomes	Global	Study-wide	5008	A=0.840	G=0.160
1000Genomes	South Asian	Sub	978	A=0.830	G=0.170
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.814	G=0.186
The Genome Aggregation Database	African	Sub	8718	A=0.876	G=0.124
The Genome Aggregation Database	American	Sub	838	A=0.790	G=0.210
The Genome Aggregation Database	East Asian	Sub	1616	A=0.855	G=0.145
The Genome Aggregation Database	Europe	Sub	18482	A=0.809	G=0.190
The Genome Aggregation Database	Global	Study-wide	29956	A=0.831	G=0.168
The Genome Aggregation Database	Other	Sub	302	A=0.850	G=0.150
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.849	G=0.150
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.833	G=0.167

PMID	Title	Author	Journal
22481050	Genetic influences on craving for alcohol.	Agrawal A	Addict Behav
25380769	Common variants in the MKL1 gene confer risk of schizophrenia.	Luo XJ	Schizophr Bull

SNP ID	p-value	Traits	Study
rs10115971	3.37E-05	alcohol craving with or without dependence	22481050

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	100977277	100977530	E067	-47357
chr9	100977643	100977889	E067	-46998
chr9	100977915	100978148	E067	-46739
chr9	100994198	100994367	E067	-30520
chr9	100994419	100994618	E067	-30269
chr9	100994659	100994741	E067	-30146
chr9	101015533	101015593	E068	-9294
chr9	101015624	101015707	E068	-9180
chr9	101015744	101016071	E068	-8816
chr9	100977643	100977889	E069	-46998
chr9	100977915	100978148	E069	-46739
chr9	101015533	101015593	E069	-9294
chr9	101015624	101015707	E069	-9180
chr9	101015744	101016071	E069	-8816
chr9	101016109	101016231	E069	-8656
chr9	101016287	101016374	E069	-8513
chr9	101019560	101019615	E069	-5272
chr9	101004830	101005051	E070	-19836
chr9	101005159	101005218	E070	-19669
chr9	100977090	100977159	E071	-47728
chr9	100977277	100977530	E071	-47357
chr9	100994198	100994367	E071	-30520
chr9	100994419	100994618	E071	-30269
chr9	100994659	100994741	E071	-30146
chr9	100994928	100995030	E071	-29857
chr9	101015744	101016071	E071	-8816
chr9	101016109	101016231	E071	-8656
chr9	101016287	101016374	E071	-8513
chr9	100977277	100977530	E072	-47357
chr9	100977643	100977889	E072	-46998
chr9	101016109	101016231	E072	-8656
chr9	101016287	101016374	E072	-8513
chr9	101015744	101016071	E073	-8816
chr9	101016109	101016231	E073	-8656
chr9	101016287	101016374	E073	-8513
chr9	101013406	101013655	E074	-11232
chr9	101013689	101014275	E074	-10612
chr9	101016109	101016231	E074	-8656
chr9	101016287	101016374	E074	-8513

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr9	101016455	101019486	E067	-5401
chr9	101016455	101019486	E068	-5401
chr9	101016455	101019486	E069	-5401
chr9	101016455	101019486	E070	-5401
chr9	101016455	101019486	E071	-5401
chr9	101016455	101019486	E072	-5401
chr9	101016455	101019486	E073	-5401
chr9	101016455	101019486	E074	-5401
chr9	101016455	101019486	E081	-5401
chr9	101016455	101019486	E082	-5401

rs10115971