rs10116484

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0215 (6455/29898,GnomAD)
T=0259 (7561/29118,TOPMED)
T=0197 (989/5008,1000G)
T=0170 (654/3854,ALSPAC)
T=0173 (642/3708,TWINSUK)
chr9:36741030 (GRCh38.p7) (9p13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
13 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.36741030C>T
GRCh37.p13 chr 9NC_000009.11:g.36741027C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.700T=0.300
1000GenomesAmericanSub694C=0.790T=0.210
1000GenomesEast AsianSub1008C=0.929T=0.071
1000GenomesEuropeSub1006C=0.836T=0.164
1000GenomesGlobalStudy-wide5008C=0.803T=0.197
1000GenomesSouth AsianSub978C=0.790T=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.830T=0.170
The Genome Aggregation DatabaseAfricanSub8694C=0.688T=0.312
The Genome Aggregation DatabaseAmericanSub834C=0.780T=0.220
The Genome Aggregation DatabaseEast AsianSub1620C=0.932T=0.068
The Genome Aggregation DatabaseEuropeSub18450C=0.816T=0.183
The Genome Aggregation DatabaseGlobalStudy-wide29898C=0.784T=0.215
The Genome Aggregation DatabaseOtherSub300C=0.810T=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.740T=0.259
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.827T=0.173
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101164840.00025alcohol dependence(early age of onset)20201924
rs101164840.00038alcohol dependence20201924

eQTL of rs10116484 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10116484 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr93673849736738607E067-2420
chr93673866836739240E067-1787
chr93673834536738456E069-2571
chr93673849736738607E069-2420
chr93673866836739240E069-1787
chr93673834536738456E071-2571
chr93673849736738607E071-2420
chr93676492236765357E07123895
chr93677971336779806E07238686
chr93678183536781915E07240808
chr93676492236765357E08123895
chr93675452436754592E08213497






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr93676552736766443E06724500
chr93676552736766443E06824500
chr93677007636770332E06829049
chr93676552736766443E06924500
chr93676552736766443E07024500
chr93673964436740080E071-947
chr93676552736766443E07124500
chr93676552736766443E07224500
chr93676552736766443E07324500
chr93676552736766443E07424500
chr93673927036739468E082-1559
chr93673964436740080E082-947
chr93676552736766443E08224500