rs10116586

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0430 (12841/29804,GnomAD)
C=0391 (11395/29118,TOPMED)
C=0324 (1624/5008,1000G)
C=0484 (1866/3854,ALSPAC)
C=0478 (1773/3708,TWINSUK)
chr9:14058549 (GRCh38.p7) (9p23)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.14058549A>C
GRCh37.p13 chr 9NC_000009.11:g.14058548A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.701C=0.299
1000GenomesAmericanSub694A=0.760C=0.240
1000GenomesEast AsianSub1008A=0.755C=0.245
1000GenomesEuropeSub1006A=0.522C=0.478
1000GenomesGlobalStudy-wide5008A=0.676C=0.324
1000GenomesSouth AsianSub978A=0.660C=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.516C=0.484
The Genome Aggregation DatabaseAfricanSub8678A=0.667C=0.333
The Genome Aggregation DatabaseAmericanSub838A=0.740C=0.260
The Genome Aggregation DatabaseEast AsianSub1616A=0.770C=0.230
The Genome Aggregation DatabaseEuropeSub18372A=0.498C=0.501
The Genome Aggregation DatabaseGlobalStudy-wide29804A=0.569C=0.430
The Genome Aggregation DatabaseOtherSub300A=0.520C=0.480
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.608C=0.391
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.522C=0.478
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101165860.000111alcohol dependence21314694

eQTL of rs10116586 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10116586 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr91409563914099075E06837091
chr91410237814102558E06843830
chr91410269514102844E06844147
chr91406242114063400E0703873
chr91410237814102558E07043830
chr91410269514102844E07044147
chr91409539414095602E07136846
chr91409563914099075E07137091
chr91410237814102558E07143830
chr91410269514102844E07144147
chr91409539414095602E07236846
chr91409563914099075E07337091
chr91408887914088944E08230331
chr91408911214089347E08230564
chr91408945614089730E08230908
chr91408996814090054E08231420
chr91409513014095290E08236582
chr91409539414095602E08236846
chr91409563914099075E08237091
chr91410269514102844E08244147