rs10135407

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0338 (10116/29856,GnomAD)
G=0290 (8446/29118,TOPMED)
G=0233 (1169/5008,1000G)
G=0420 (1619/3854,ALSPAC)
G=0414 (1536/3708,TWINSUK)
chr14:42175414 (GRCh38.p7) (14q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.42175414A>G
GRCh37.p13 chr 14NC_000014.8:g.42644617A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.860G=0.140
1000GenomesAmericanSub694A=0.770G=0.230
1000GenomesEast AsianSub1008A=0.965G=0.035
1000GenomesEuropeSub1006A=0.556G=0.444
1000GenomesGlobalStudy-wide5008A=0.767G=0.233
1000GenomesSouth AsianSub978A=0.650G=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.580G=0.420
The Genome Aggregation DatabaseAfricanSub8714A=0.824G=0.176
The Genome Aggregation DatabaseAmericanSub832A=0.770G=0.230
The Genome Aggregation DatabaseEast AsianSub1610A=0.939G=0.061
The Genome Aggregation DatabaseEuropeSub18400A=0.556G=0.443
The Genome Aggregation DatabaseGlobalStudy-wide29856A=0.661G=0.338
The Genome Aggregation DatabaseOtherSub300A=0.580G=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.709G=0.290
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.586G=0.414
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs101354072.9E-05alcoholism (heaviness of drinking)21529783

eQTL of rs10135407 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10135407 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144269233642692777E06747719
chr144269137042691639E07046753
chr144269205042692186E08247433
chr144269233642692777E08247719