rs10136042

Homo sapiens
C>A / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
A=0278 (8203/29484,GnomAD)
A=0371 (10829/29118,TOPMED)
A=0291 (1456/5008,1000G)
A=0135 (521/3854,ALSPAC)
A=0150 (557/3708,TWINSUK)
chr14:57199043 (GRCh38.p7) (14q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.57199043C>A
GRCh38.p7 chr 14NC_000014.9:g.57199043C>T
GRCh37.p13 chr 14NC_000014.8:g.57665761C>A
GRCh37.p13 chr 14NC_000014.8:g.57665761C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.227A=0.773
1000GenomesAmericanSub694C=0.880A=0.120
1000GenomesEast AsianSub1008C=0.886A=0.114
1000GenomesEuropeSub1006C=0.882A=0.118
1000GenomesGlobalStudy-wide5008C=0.709A=0.291
1000GenomesSouth AsianSub978C=0.880A=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.865A=0.135
The Genome Aggregation DatabaseAfricanSub8516C=0.349T=0.000
The Genome Aggregation DatabaseAmericanSub816C=0.890T=0.00,
The Genome Aggregation DatabaseEast AsianSub1614C=0.856T=0.001
The Genome Aggregation DatabaseEuropeSub18238C=0.874T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29484C=0.721T=0.000
The Genome Aggregation DatabaseOtherSub300C=0.860T=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.628A=0.371
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.850A=0.150
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs101360427.9E-05alcohol consumption23743675

eQTL of rs10136042 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10136042 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145764085457640986E081-24513
chr145764112257641684E081-23815
chr145764209457642148E081-23351
chr145764228557642434E081-23065