rs10145188

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0280 (8367/29822,GnomAD)
T=0372 (10831/29118,TOPMED)
T=0290 (1453/5008,1000G)
T=0135 (520/3854,ALSPAC)
T=0150 (557/3708,TWINSUK)
chr14:57201278 (GRCh38.p7) (14q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.57201278G>T
GRCh37.p13 chr 14NC_000014.8:g.57667996G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.228T=0.772
1000GenomesAmericanSub694G=0.880T=0.120
1000GenomesEast AsianSub1008G=0.886T=0.114
1000GenomesEuropeSub1006G=0.882T=0.118
1000GenomesGlobalStudy-wide5008G=0.710T=0.290
1000GenomesSouth AsianSub978G=0.880T=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.865T=0.135
The Genome Aggregation DatabaseAfricanSub8686G=0.348T=0.652
The Genome Aggregation DatabaseAmericanSub834G=0.890T=0.110
The Genome Aggregation DatabaseEast AsianSub1612G=0.855T=0.145
The Genome Aggregation DatabaseEuropeSub18388G=0.873T=0.127
The Genome Aggregation DatabaseGlobalStudy-wide29822G=0.719T=0.280
The Genome Aggregation DatabaseOtherSub302G=0.850T=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.628T=0.372
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.850T=0.150
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs101451887.46E-05alcohol consumption23743675

eQTL of rs10145188 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10145188 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145764085457640986E081-27010
chr145764112257641684E081-26312
chr145764209457642148E081-25848
chr145764228557642434E081-25562