rs10153975

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0121 (3643/29942,GnomAD)
C=0086 (2514/29118,TOPMED)
C=0113 (565/5008,1000G)
C=0117 (452/3854,ALSPAC)
C=0115 (427/3708,TWINSUK)
chr20:60815936 (GRCh38.p7) (20q13.33)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.60815936T>C
GRCh37.p13 chr 20NC_000020.10:g.59390992T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.955C=0.045
1000GenomesAmericanSub694T=0.910C=0.090
1000GenomesEast AsianSub1008T=0.801C=0.199
1000GenomesEuropeSub1006T=0.880C=0.120
1000GenomesGlobalStudy-wide5008T=0.887C=0.113
1000GenomesSouth AsianSub978T=0.880C=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.883C=0.117
The Genome Aggregation DatabaseAfricanSub8702T=0.932C=0.068
The Genome Aggregation DatabaseAmericanSub838T=0.900C=0.100
The Genome Aggregation DatabaseEast AsianSub1622T=0.821C=0.179
The Genome Aggregation DatabaseEuropeSub18478T=0.856C=0.143
The Genome Aggregation DatabaseGlobalStudy-wide29942T=0.878C=0.121
The Genome Aggregation DatabaseOtherSub302T=0.930C=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.913C=0.086
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.885C=0.115
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101539750.000833alcohol dependence20201924

eQTL of rs10153975 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10153975 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr205941539959415449E08124407
chr205941577459415974E08124782
chr205941601459416396E08125022