SNP Detail Info-rs10158534

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

LOC105371609 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0393 (11785/29950,GnomAD)
G=0391 (11399/29118,TOPMED)
G=0427 (2138/5008,1000G)
G=0402 (1550/3854,ALSPAC)
G=0402 (1491/3708,TWINSUK)

Position: chr1:170203276 (GRCh38.p7) (1q24.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.170203276T>G
GRCh37.p13 chr 1	NC_000001.10:g.170172417T>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105371609 transcript variant X1	XR_001738284.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X3	XR_001738285.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X4	XR_001738286.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X5	XR_001738287.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X7	XR_001738288.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X8	XR_001738289.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X10	XR_001738290.1:n.	N/A	Intron Variant
LOC105371609 transcript variant X2	XR_922266.2:n.	N/A	Intron Variant
LOC105371609 transcript variant X6	XR_922269.2:n.	N/A	Intron Variant
LOC105371609 transcript variant X9	XR_922275.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.595	G=0.405
1000Genomes	American	Sub	694	T=0.600	G=0.400
1000Genomes	East Asian	Sub	1008	T=0.737	G=0.263
1000Genomes	Europe	Sub	1006	T=0.556	G=0.444
1000Genomes	Global	Study-wide	5008	T=0.573	G=0.427
1000Genomes	South Asian	Sub	978	T=0.370	G=0.630
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.598	G=0.402
The Genome Aggregation Database	African	Sub	8716	T=0.608	G=0.392
The Genome Aggregation Database	American	Sub	834	T=0.630	G=0.370
The Genome Aggregation Database	East Asian	Sub	1620	T=0.745	G=0.255
The Genome Aggregation Database	Europe	Sub	18478	T=0.594	G=0.405
The Genome Aggregation Database	Global	Study-wide	29950	T=0.606	G=0.393
The Genome Aggregation Database	Other	Sub	302	T=0.470	G=0.530
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.608	G=0.391
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.598	G=0.402

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10158534	0.000461	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs10158534