rs10158534

Homo sapiens
T>G
LOC105371609 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0393 (11785/29950,GnomAD)
G=0391 (11399/29118,TOPMED)
G=0427 (2138/5008,1000G)
G=0402 (1550/3854,ALSPAC)
G=0402 (1491/3708,TWINSUK)
chr1:170203276 (GRCh38.p7) (1q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.170203276T>G
GRCh37.p13 chr 1NC_000001.10:g.170172417T>G

Gene: LOC105371609, uncharacterized LOC105371609(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105371609 transcript variant X1XR_001738284.1:n.N/AIntron Variant
LOC105371609 transcript variant X3XR_001738285.1:n.N/AIntron Variant
LOC105371609 transcript variant X4XR_001738286.1:n.N/AIntron Variant
LOC105371609 transcript variant X5XR_001738287.1:n.N/AIntron Variant
LOC105371609 transcript variant X7XR_001738288.1:n.N/AIntron Variant
LOC105371609 transcript variant X8XR_001738289.1:n.N/AIntron Variant
LOC105371609 transcript variant X10XR_001738290.1:n.N/AIntron Variant
LOC105371609 transcript variant X2XR_922266.2:n.N/AIntron Variant
LOC105371609 transcript variant X6XR_922269.2:n.N/AIntron Variant
LOC105371609 transcript variant X9XR_922275.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.595G=0.405
1000GenomesAmericanSub694T=0.600G=0.400
1000GenomesEast AsianSub1008T=0.737G=0.263
1000GenomesEuropeSub1006T=0.556G=0.444
1000GenomesGlobalStudy-wide5008T=0.573G=0.427
1000GenomesSouth AsianSub978T=0.370G=0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.598G=0.402
The Genome Aggregation DatabaseAfricanSub8716T=0.608G=0.392
The Genome Aggregation DatabaseAmericanSub834T=0.630G=0.370
The Genome Aggregation DatabaseEast AsianSub1620T=0.745G=0.255
The Genome Aggregation DatabaseEuropeSub18478T=0.594G=0.405
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.606G=0.393
The Genome Aggregation DatabaseOtherSub302T=0.470G=0.530
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.608G=0.391
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.598G=0.402
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101585340.000461alcohol dependence20201924

eQTL of rs10158534 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10158534 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.