rs10158567

Homo sapiens
G>A
RGS7 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0402 (12030/29882,GnomAD)
A=0491 (14295/29116,TOPMED)
A=0448 (2242/5008,1000G)
A=0260 (1001/3854,ALSPAC)
A=0258 (957/3708,TWINSUK)
chr1:241125210 (GRCh38.p7) (1q43)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.241125210G>A
GRCh37.p13 chr 1NC_000001.10:g.241288510G>A

Gene: RGS7, regulator of G-protein signaling 7(minus strand)

Molecule type Change Amino acid[Codon] SO Term
RGS7 transcript variant 2NM_001282773.1:c.N/AIntron Variant
RGS7 transcript variant 3NM_001282775.1:c.N/AIntron Variant
RGS7 transcript variant 4NM_001282778.1:c.N/AIntron Variant
RGS7 transcript variant 1NM_002924.5:c.N/AIntron Variant
RGS7 transcript variant X1XM_005273218.3:c.N/AIntron Variant
RGS7 transcript variant X5XM_011544246.2:c.N/AIntron Variant
RGS7 transcript variant X2XM_017002001.1:c.N/AIntron Variant
RGS7 transcript variant X3XM_017002002.1:c.N/AIntron Variant
RGS7 transcript variant X7XM_017002003.1:c.N/AIntron Variant
RGS7 transcript variant X8XM_017002004.1:c.N/AIntron Variant
RGS7 transcript variant X9XM_017002005.1:c.N/AIntron Variant
RGS7 transcript variant X10XM_017002006.1:c.N/AIntron Variant
RGS7 transcript variant X11XM_017002007.1:c.N/AIntron Variant
RGS7 transcript variant X12XM_017002008.1:c.N/AIntron Variant
RGS7 transcript variant X14XM_017002010.1:c.N/AIntron Variant
RGS7 transcript variant X4XM_006711800.3:c.N/AGenic Upstream Transcript Variant
RGS7 transcript variant X6XM_011544247.2:c.N/AGenic Upstream Transcript Variant
RGS7 transcript variant X10XM_017002009.1:c.N/AGenic Upstream Transcript Variant
RGS7 transcript variant X15XM_017002011.1:c.N/AGenic Upstream Transcript Variant
RGS7 transcript variant X16XM_017002012.1:c.N/AGenic Upstream Transcript Variant
RGS7 transcript variant X13XM_017002013.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.143A=0.857
1000GenomesAmericanSub694G=0.680A=0.320
1000GenomesEast AsianSub1008G=0.622A=0.378
1000GenomesEuropeSub1006G=0.745A=0.255
1000GenomesGlobalStudy-wide5008G=0.552A=0.448
1000GenomesSouth AsianSub978G=0.740A=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.740A=0.260
The Genome Aggregation DatabaseAfricanSub8698G=0.217A=0.783
The Genome Aggregation DatabaseAmericanSub836G=0.730A=0.270
The Genome Aggregation DatabaseEast AsianSub1610G=0.586A=0.414
The Genome Aggregation DatabaseEuropeSub18438G=0.769A=0.230
The Genome Aggregation DatabaseGlobalStudy-wide29882G=0.597A=0.402
The Genome Aggregation DatabaseOtherSub300G=0.750A=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.509A=0.491
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.742A=0.258
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs101585670.000716alcohol dependence21314694

eQTL of rs10158567 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10158567 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1241242355241242698E073-45812
chr1241307188241307332E08118678
chr1241321839241321911E08233329