SNP Detail Info-rs10167668

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0103 (3097/29962,GnomAD)
G=0114 (3336/29116,TOPMED)
G=0084 (419/5008,1000G)
G=0080 (307/3854,ALSPAC)
G=0074 (273/3708,TWINSUK)

Position: chr2:45355180 (GRCh38.p7) (2p21)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.45355180A>G
GRCh37.p13 chr 2	NC_000002.11:g.45582319A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.845	G=0.155
1000Genomes	American	Sub	694	A=0.900	G=0.100
1000Genomes	East Asian	Sub	1008	A=0.999	G=0.001
1000Genomes	Europe	Sub	1006	A=0.913	G=0.087
1000Genomes	Global	Study-wide	5008	A=0.916	G=0.084
1000Genomes	South Asian	Sub	978	A=0.950	G=0.050
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.920	G=0.080
The Genome Aggregation Database	African	Sub	8720	A=0.849	G=0.151
The Genome Aggregation Database	American	Sub	838	A=0.950	G=0.050
The Genome Aggregation Database	East Asian	Sub	1622	A=0.998	G=0.002
The Genome Aggregation Database	Europe	Sub	18480	A=0.907	G=0.092
The Genome Aggregation Database	Global	Study-wide	29962	A=0.896	G=0.103
The Genome Aggregation Database	Other	Sub	302	A=0.920	G=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.885	G=0.114
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.926	G=0.074

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs10167668	1.12E-06	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	45579658	45579708	E070	-2611
chr2	45579796	45580031	E070	-2288
chr2	45580037	45580146	E070	-2173
chr2	45580729	45580802	E070	-1517
chr2	45580938	45581483	E070	-836

rs10167668