rs1019233

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0164 (4925/29934,GnomAD)
T=0149 (4356/29118,TOPMED)
T=0207 (1036/5008,1000G)
T=0208 (802/3854,ALSPAC)
T=0196 (726/3708,TWINSUK)
chr7:21048964 (GRCh38.p7) (7p15.3)
ND
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.21048964C>T
GRCh37.p13 chr 7NC_000007.13:g.21088583C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.971T=0.029
1000GenomesAmericanSub694C=0.670T=0.330
1000GenomesEast AsianSub1008C=0.708T=0.292
1000GenomesEuropeSub1006C=0.790T=0.210
1000GenomesGlobalStudy-wide5008C=0.793T=0.207
1000GenomesSouth AsianSub978C=0.730T=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.792T=0.208
The Genome Aggregation DatabaseAfricanSub8724C=0.943T=0.057
The Genome Aggregation DatabaseAmericanSub832C=0.680T=0.320
The Genome Aggregation DatabaseEast AsianSub1614C=0.710T=0.290
The Genome Aggregation DatabaseEuropeSub18462C=0.805T=0.194
The Genome Aggregation DatabaseGlobalStudy-wide29934C=0.835T=0.164
The Genome Aggregation DatabaseOtherSub302C=0.710T=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.850T=0.149
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.804T=0.196
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs10192330.000886nicotine dependence17158188

eQTL of rs1019233 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs1019233 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr72106284221062926E070-25657
chr72106329021063434E070-25149
chr72106381521063992E070-24591
chr72106407821064159E070-24424
chr72106419621064326E070-24257
chr72106446021064590E070-23993
chr72106729321067357E070-21226
chr72106968121070377E070-18206
chr72107066621070752E070-17831
chr72108081721080910E070-7673
chr72108102621081364E070-7219
chr72108137221081770E070-6813
chr72108178621082156E070-6427
chr72108220521082350E070-6233
chr72108237221082422E070-6161
chr72108248221082952E070-5631
chr72108298021083175E070-5408
chr72108321521083259E070-5324
chr72108402821084283E070-4300
chr72108453521084770E070-3813
chr72108478121085029E070-3554
chr72108507521085180E070-3403
chr72108670621086756E070-1827
chr72106781821068363E081-20220
chr72106862221069136E081-19447
chr72106968121070377E081-18206
chr72106836521068595E082-19988
chr72106968121070377E082-18206
chr72108102621081364E082-7219
chr72108237221082422E082-6161
chr72108248221082952E082-5631
chr72108298021083175E082-5408