rs10198241

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0425 (12697/29850,GnomAD)
T==0406 (11829/29118,TOPMED)
T==0380 (1905/5008,1000G)
T==0495 (1909/3854,ALSPAC)
C=0495 (1834/3708,TWINSUK)
chr2:226115660 (GRCh38.p7) (2q36.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.226115660T>C
GRCh37.p13 chr 2NC_000002.11:g.226980376T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.258C=0.742
1000GenomesAmericanSub694T=0.510C=0.490
1000GenomesEast AsianSub1008T=0.308C=0.692
1000GenomesEuropeSub1006T=0.484C=0.516
1000GenomesGlobalStudy-wide5008T=0.380C=0.620
1000GenomesSouth AsianSub978T=0.420C=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.495C=0.505
The Genome Aggregation DatabaseAfricanSub8702T=0.298C=0.702
The Genome Aggregation DatabaseAmericanSub836T=0.550C=0.450
The Genome Aggregation DatabaseEast AsianSub1590T=0.317C=0.683
The Genome Aggregation DatabaseEuropeSub18420T=0.489C=0.510
The Genome Aggregation DatabaseGlobalStudy-wide29850T=0.425C=0.574
The Genome Aggregation DatabaseOtherSub302T=0.400C=0.600
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.406C=0.593
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.505C=0.495
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs101982411E-06alcohol dependence29071344

eQTL of rs10198241 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10198241 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2226931245226931333E074-49043
chr2226996019226996281E08115643
chr2226996333226996425E08115957