SNP Detail Info-rs10213966

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0177 (5319/29956,GnomAD)
G=0136 (3959/29118,TOPMED)
G=0193 (969/5008,1000G)
G=0213 (819/3854,ALSPAC)
G=0206 (765/3708,TWINSUK)

Position: chr5:121461456 (GRCh38.p7) (5q23.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 5 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.121461456A>G
GRCh37.p13 chr 5	NC_000005.9:g.120797151A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.974	G=0.026
1000Genomes	American	Sub	694	A=0.830	G=0.170
1000Genomes	East Asian	Sub	1008	A=0.500	G=0.500
1000Genomes	Europe	Sub	1006	A=0.792	G=0.208
1000Genomes	Global	Study-wide	5008	A=0.807	G=0.193
1000Genomes	South Asian	Sub	978	A=0.900	G=0.100
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.787	G=0.213
The Genome Aggregation Database	African	Sub	8726	A=0.952	G=0.048
The Genome Aggregation Database	American	Sub	836	A=0.850	G=0.150
The Genome Aggregation Database	East Asian	Sub	1616	A=0.520	G=0.480
The Genome Aggregation Database	Europe	Sub	18476	A=0.786	G=0.213
The Genome Aggregation Database	Global	Study-wide	29956	A=0.822	G=0.177
The Genome Aggregation Database	Other	Sub	302	A=0.800	G=0.200
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.864	G=0.136
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.794	G=0.206

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10213966	0.000744	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	120750901	120751274	E070	-45877
chr5	120751497	120751556	E070	-45595
chr5	120835961	120836037	E070	38810
chr5	120836114	120836231	E070	38963
chr5	120836251	120836332	E070	39100

rs10213966