rs10215376

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0300 (9011/29954,GnomAD)
T=0291 (8492/29118,TOPMED)
T=0399 (2000/5008,1000G)
T=0258 (994/3854,ALSPAC)
T=0281 (1041/3708,TWINSUK)
chr7:36038205 (GRCh38.p7) (7p14.2)
ND
GWASdb2
1   publication(s)
See rs on genome
108 Enhancers around
16 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.36038205C>T
GRCh37.p13 chr 7NC_000007.13:g.36077815C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.675T=0.325
1000GenomesAmericanSub694C=0.580T=0.420
1000GenomesEast AsianSub1008C=0.517T=0.483
1000GenomesEuropeSub1006C=0.750T=0.250
1000GenomesGlobalStudy-wide5008C=0.601T=0.399
1000GenomesSouth AsianSub978C=0.450T=0.550
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.742T=0.258
The Genome Aggregation DatabaseAfricanSub8708C=0.689T=0.311
The Genome Aggregation DatabaseAmericanSub838C=0.530T=0.470
The Genome Aggregation DatabaseEast AsianSub1618C=0.519T=0.481
The Genome Aggregation DatabaseEuropeSub18488C=0.727T=0.272
The Genome Aggregation DatabaseGlobalStudy-wide29954C=0.699T=0.300
The Genome Aggregation DatabaseOtherSub302C=0.710T=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.708T=0.291
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.719T=0.281
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs102153762.53E-05alcohol and nictotine co-dependence20158304

eQTL of rs10215376 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr7:36077815AC007551.3ENSG00000228878.3C>T4.5343e-3237589Cortex

meQTL of rs10215376 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr73607167236071760E067-6055
chr73607199736072385E067-5430
chr73607618336077449E067-366
chr73606170236062134E068-15681
chr73606230336062343E068-15472
chr73606236836062418E068-15397
chr73606283136062901E068-14914
chr73606293636063052E068-14763
chr73606307036063159E068-14656
chr73606323936063289E068-14526
chr73606334736063525E068-14290
chr73607476436074952E068-2863
chr73607498036075070E068-2745
chr73607507336075200E068-2615
chr73607523636075294E068-2521
chr73607530136075351E068-2464
chr73607543236075507E068-2308
chr73607560236075785E068-2030
chr73607597436076062E068-1753
chr73607618336077449E068-366
chr73608469836085976E0686883
chr73605025236050306E069-27509
chr73605035136051621E069-26194
chr73606100536061310E069-16505
chr73606134936061558E069-16257
chr73606170236062134E069-15681
chr73606293636063052E069-14763
chr73606307036063159E069-14656
chr73607167236071760E069-6055
chr73607199736072385E069-5430
chr73607498036075070E069-2745
chr73607507336075200E069-2615
chr73607523636075294E069-2521
chr73607530136075351E069-2464
chr73607543236075507E069-2308
chr73607560236075785E069-2030
chr73607597436076062E069-1753
chr73607618336077449E069-366
chr73605035136051621E070-26194
chr73606293636063052E070-14763
chr73606307036063159E070-14656
chr73606323936063289E070-14526
chr73606334736063525E070-14290
chr73607476436074952E070-2863
chr73607498036075070E070-2745
chr73607507336075200E070-2615
chr73607523636075294E070-2521
chr73607530136075351E070-2464
chr73607543236075507E070-2308
chr73607560236075785E070-2030
chr73607597436076062E070-1753
chr73607618336077449E070-366
chr73607760036077650E070-165
chr73607799736078098E070182
chr73607819436078264E070379
chr73606134936061558E071-16257
chr73606170236062134E071-15681
chr73606283136062901E071-14914
chr73606293636063052E071-14763
chr73606307036063159E071-14656
chr73607167236071760E071-6055
chr73607199736072385E071-5430
chr73607498036075070E071-2745
chr73607507336075200E071-2615
chr73607523636075294E071-2521
chr73607530136075351E071-2464
chr73607543236075507E071-2308
chr73607560236075785E071-2030
chr73607597436076062E071-1753
chr73607618336077449E071-366
chr73607760036077650E071-165
chr73607799736078098E071182
chr73607819436078264E071379
chr73606170236062134E072-15681
chr73607597436076062E072-1753
chr73607618336077449E072-366
chr73606134936061558E073-16257
chr73606170236062134E073-15681
chr73606230336062343E073-15472
chr73606236836062418E073-15397
chr73607199736072385E073-5430
chr73607597436076062E073-1753
chr73607618336077449E073-366
chr73608761736088268E0739802
chr73608828336088796E07310468
chr73606170236062134E074-15681
chr73606230336062343E074-15472
chr73606236836062418E074-15397
chr73606283136062901E074-14914
chr73606293636063052E074-14763
chr73606307036063159E074-14656
chr73607523636075294E074-2521
chr73607530136075351E074-2464
chr73607543236075507E074-2308
chr73607618336077449E074-366
chr73608469836085976E0746883
chr73602836336028806E081-49009
chr73602886436029127E081-48688
chr73605004136050109E081-27706
chr73605025236050306E081-27509
chr73605035136051621E081-26194
chr73605286236052958E081-24857
chr73605300236053676E081-24139
chr73605379536053953E081-23862
chr73606134936061558E081-16257
chr73608761736088268E0819802
chr73608828336088796E08110468
chr73608761736088268E0829802










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr73606807436068133E068-9682
chr73606820636068383E068-9432
chr73606753236067592E069-10223
chr73606807436068133E069-9682
chr73606711636067196E070-10619
chr73606735536067395E070-10420
chr73606753236067592E070-10223
chr73606807436068133E070-9682
chr73606735536067395E071-10420
chr73606753236067592E071-10223
chr73606807436068133E071-9682
chr73606820636068383E071-9432
chr73606807436068133E072-9682
chr73606820636068383E072-9432
chr73606807436068133E074-9682
chr73606820636068383E074-9432