SNP Detail Info-rs10219728

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0482 (14407/29862,GnomAD)
A==0482 (14060/29118,TOPMED)
A==0456 (2286/5008,1000G)
A==0488 (1879/3854,ALSPAC)
A==0483 (1792/3708,TWINSUK)

Position: chr12:17486887 (GRCh38.p7) (12p12.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 12	NC_000012.12:g.17486887A>G
GRCh37.p13 chr 12	NC_000012.11:g.17639821A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.495	G=0.505
1000Genomes	American	Sub	694	A=0.460	G=0.540
1000Genomes	East Asian	Sub	1008	A=0.432	G=0.568
1000Genomes	Europe	Sub	1006	A=0.503	G=0.497
1000Genomes	Global	Study-wide	5008	A=0.456	G=0.544
1000Genomes	South Asian	Sub	978	A=0.380	G=0.620
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.488	G=0.512
The Genome Aggregation Database	African	Sub	8698	A=0.484	G=0.516
The Genome Aggregation Database	American	Sub	838	A=0.430	G=0.570
The Genome Aggregation Database	East Asian	Sub	1608	A=0.392	G=0.608
The Genome Aggregation Database	Europe	Sub	18416	A=0.493	G=0.506
The Genome Aggregation Database	Global	Study-wide	29862	A=0.482	G=0.517
The Genome Aggregation Database	Other	Sub	302	A=0.410	G=0.590
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.482	G=0.517
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.483	G=0.517

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs10219728	0.00043	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs10219728