rs10225194

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0307 (9160/29828,GnomAD)
G=0303 (8843/29118,TOPMED)
G=0256 (1283/5008,1000G)
G=0379 (1460/3854,ALSPAC)
G=0393 (1459/3708,TWINSUK)
chr7:10239179 (GRCh38.p7) (7p21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.10239179T>G
GRCh37.p13 chr 7NC_000007.13:g.10278806T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.806G=0.194
1000GenomesAmericanSub694T=0.630G=0.370
1000GenomesEast AsianSub1008T=0.871G=0.129
1000GenomesEuropeSub1006T=0.631G=0.369
1000GenomesGlobalStudy-wide5008T=0.744G=0.256
1000GenomesSouth AsianSub978T=0.730G=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.621G=0.379
The Genome Aggregation DatabaseAfricanSub8694T=0.781G=0.219
The Genome Aggregation DatabaseAmericanSub830T=0.640G=0.360
The Genome Aggregation DatabaseEast AsianSub1586T=0.885G=0.115
The Genome Aggregation DatabaseEuropeSub18416T=0.636G=0.363
The Genome Aggregation DatabaseGlobalStudy-wide29828T=0.692G=0.307
The Genome Aggregation DatabaseOtherSub302T=0.710G=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.696G=0.303
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.607G=0.393
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs102251940.000297alcohol dependence20201924

eQTL of rs10225194 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10225194 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr71026487810265292E069-13514
chr71026487810265292E072-13514