SNP Detail Info-rs10249276

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0132 (3952/29834,GnomAD)
A==0184 (5372/29118,TOPMED)
A==0147 (737/5008,1000G)
A==0081 (312/3854,ALSPAC)
A==0080 (295/3708,TWINSUK)

Position: chr7:118938630 (GRCh38.p7) (7q31.31)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 2 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 7	NC_000007.14:g.118938630A>G
GRCh37.p13 chr 7	NC_000007.13:g.118578684A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.352	G=0.648
1000Genomes	American	Sub	694	A=0.100	G=0.900
1000Genomes	East Asian	Sub	1008	A=0.081	G=0.919
1000Genomes	Europe	Sub	1006	A=0.073	G=0.927
1000Genomes	Global	Study-wide	5008	A=0.147	G=0.853
1000Genomes	South Asian	Sub	978	A=0.050	G=0.950
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.081	G=0.919
The Genome Aggregation Database	African	Sub	8702	A=0.308	G=0.692
The Genome Aggregation Database	American	Sub	830	A=0.110	G=0.890
The Genome Aggregation Database	East Asian	Sub	1578	A=0.089	G=0.911
The Genome Aggregation Database	Europe	Sub	18422	A=0.054	G=0.945
The Genome Aggregation Database	Global	Study-wide	29834	A=0.132	G=0.867
The Genome Aggregation Database	Other	Sub	302	A=0.120	G=0.880
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.184	G=0.815
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.080	G=0.920

PMID	Title	Author	Journal
22613542	ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.	Chen XD	Chin Med J (Engl)

SNP ID	p-value	Traits	Study
rs10249276	7.99E-07	alcohol consumption	22613542

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr7	118614632	118614702	E081	35948
chr7	118614812	118615340	E081	36128

rs10249276