rs10253361

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0362 (10829/29908,GnomAD)
C==0353 (10292/29118,TOPMED)
C==0409 (2048/5008,1000G)
C==0454 (1750/3854,ALSPAC)
C==0430 (1594/3708,TWINSUK)
chr7:121635175 (GRCh38.p7) (7q31.32)
AD
GWASdb2 | GWASCatalog
2   publication(s)
See rs on genome
56 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.121635175C>T
GRCh37.p13 chr 7NC_000007.13:g.121275229C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.172T=0.828
1000GenomesAmericanSub694C=0.450T=0.550
1000GenomesEast AsianSub1008C=0.610T=0.390
1000GenomesEuropeSub1006C=0.442T=0.558
1000GenomesGlobalStudy-wide5008C=0.409T=0.591
1000GenomesSouth AsianSub978C=0.460T=0.540
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.454T=0.546
The Genome Aggregation DatabaseAfricanSub8718C=0.224T=0.776
The Genome Aggregation DatabaseAmericanSub834C=0.500T=0.500
The Genome Aggregation DatabaseEast AsianSub1602C=0.631T=0.369
The Genome Aggregation DatabaseEuropeSub18452C=0.395T=0.604
The Genome Aggregation DatabaseGlobalStudy-wide29908C=0.362T=0.637
The Genome Aggregation DatabaseOtherSub302C=0.500T=0.500
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.353T=0.646
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.430T=0.570
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry
22119407Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.Bostrom MAAm J Kidney Dis

P-Value

SNP ID p-value Traits Study
rs102533610.000006alcoholism (alcohol dependence factor score)21529783
rs102533616.00E-06alcohol dependence21529783

eQTL of rs10253361 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs10253361 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7121316481121316609E07041252
chr7121317220121317312E07041991
chr7121317531121317685E07042302
chr7121245809121245860E071-29369
chr7121245974121246116E071-29113
chr7121265098121265509E071-9720
chr7121260392121260570E074-14659
chr7121234630121234680E081-40549
chr7121235500121235607E081-39622
chr7121235657121236780E081-38449
chr7121237168121237315E081-37914
chr7121237457121237526E081-37703
chr7121241605121241655E081-33574
chr7121241864121242290E081-32939
chr7121242360121242426E081-32803
chr7121242448121242515E081-32714
chr7121242584121242750E081-32479
chr7121242961121243011E081-32218
chr7121243124121243197E081-32032
chr7121243575121243756E081-31473
chr7121243846121243896E081-31333
chr7121244059121244274E081-30955
chr7121244400121245784E081-29445
chr7121245809121245860E081-29369
chr7121245974121246116E081-29113
chr7121247936121248062E081-27167
chr7121248157121248541E081-26688
chr7121248900121249124E081-26105
chr7121249351121249488E081-25741
chr7121250007121250121E081-25108
chr7121250143121250249E081-24980
chr7121260392121260570E081-14659
chr7121260582121260885E081-14344
chr7121260909121261498E081-13731
chr7121261627121261937E081-13292
chr7121264892121264942E081-10287
chr7121241605121241655E082-33574
chr7121241864121242290E082-32939
chr7121242360121242426E082-32803
chr7121242448121242515E082-32714
chr7121242584121242750E082-32479
chr7121243846121243896E082-31333
chr7121244059121244274E082-30955
chr7121244400121245784E082-29445
chr7121245809121245860E082-29369
chr7121245974121246116E082-29113
chr7121247936121248062E082-27167
chr7121248157121248541E082-26688
chr7121248900121249124E082-26105
chr7121249351121249488E082-25741
chr7121250007121250121E082-25108
chr7121250143121250249E082-24980
chr7121263086121263137E082-12092
chr7121263230121263469E082-11760
chr7121263593121263776E082-11453
chr7121265861121265951E082-9278